Superfund Research Program
Meta-Omics of Microbial Communities Involved in Bioremediation
Project Leader: Lisa Alvarez-Cohen
Grant Number: P42ES004705
Funding Period: 2000-2017
Project-Specific Links
Title: Sustainable syntrophic growth of Dehalococcoides ethenogenes strain 195 with Desulfovibrio vulgaris Hildenborough and Methanobacterium congolense: global transcriptomic and proteomic analysis
Accession Number: GSE26815
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE26815
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by array
Organism(s): Dehalococcoides
Summary: The syntrophic growth of strain 195 with Desulfovibrio vulgaris Hildenborough (DVH) and/or Methanobacterium congolense (MC) enhanced TCE dechlorination process by faster dechlorination rate and more robust growth. Transcriptomes of strain 195 grown in isolation, co- and tri-cultures were obtained by microarray experiments to find out the differential expressed genes corresponding to the syntrophic growth. Thus we can better understand the role of DVH and MC within this syntrophy.
Publication(s) associated with this dataset:- Men Y, Feil H, VerBerkmoes NC, Shah M, Johnson DR, Lee PH, West KA, Zinder SH, Andersen GL, Alvarez-Cohen L. 2012. Sustainable syntrophic growth of Dehalococcoides ethenogenes strain 195 with Desulfovibrio vulgaris Hildenborough and Methanobacterium congolense: global transcriptomic and proteomic analyses. ISME J 6:410-421. doi:10.1038/ismej.2011.111 PMID:21881617 PMCID:PMC3260503