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University of California-San Diego: Dataset Details, ID=GSE56080

Superfund Research Program

Toxicogenomic Analysis of Nuclear Xenobiotic Receptors

Project Leader: Ronald M. Evans (Salk Institute for Biological Studies)
Grant Number: P42ES010337
Funding Period: 2005-2017
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Title: Orphan Nuclear Receptor ERRγ is required for pancreatic islet beta-cell maturation

Accession Number: GSE56080

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE56080

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Mus musculus

Summary: We characterized the effect of loss of ERRγ expression in mouse pancreatic islets using adenoviral constructs.

Publication(s) associated with this dataset:
  • Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng TW, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. 2016. ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells. Cell Metab 23(4):622-634. doi:10.1016/j.cmet.2016.03.005 PMID:27076077 PMCID:PMC4832237
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