Superfund Research Program
Effect of Underlying Liver Diseases on Fibrosis Induced by Superfund Toxicants
Project Leader: David A. Brenner
Grant Number: P42ES010337
Funding Period: 2011-2017
Project-Specific Links
- Project Summary
Title: Intestinally-biased FXR agonism browns white adipose tissue preventing obesity and insulin resistance
Accession Number: SRP048631
Link to Dataset: https://trace.ncbi.nlm.nih.gov/Traces/sra/?study=SRP048631
Repository: Sequence Read Archive (SRA)
Data Type(s): Nucleotide Sequence
Experiment Type(s): Transcriptome analysis
Organism(s): Mus musculus
Publication(s) associated with this dataset:- Fang S, Suh J, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky J, Saltiel AR, Downes M, Evans RM. 2015. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med 21(2):159-165. doi:10.1038/nm.3760 PMID:25559344 PMCID:PMC4320010