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University of California-San Diego: Dataset Details, ID=SRP048631

Superfund Research Program

Effect of Underlying Liver Diseases on Fibrosis Induced by Superfund Toxicants

Project Leader: David A. Brenner
Grant Number: P42ES010337
Funding Period: 2011-2017
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Title: Intestinally-biased FXR agonism browns white adipose tissue preventing obesity and insulin resistance

Accession Number: SRP048631

Link to Dataset: https://trace.ncbi.nlm.nih.gov/Traces/sra/?study=SRP048631

Repository: Sequence Read Archive (SRA)

Data Type(s): Nucleotide Sequence

Experiment Type(s): Transcriptome analysis

Organism(s): Mus musculus

Publication(s) associated with this dataset:
  • Fang S, Suh J, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky J, Saltiel AR, Downes M, Evans RM. 2015. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med 21(2):159-165. doi:10.1038/nm.3760 PMID:25559344 PMCID:PMC4320010
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Last Reviewed: April 09, 2025