Superfund Research Program
The Role of Reactive Oxygen Species and the Microbiome in Toxicant Induced Liver Fibrosis
Project Leader: David A. Brenner
Co-Investigator: Rohit Loomba
Grant Number: P42ES010337
Funding Period: 2017-2023
Project-Specific Links
- Project Summary
Title: Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms
Accession Number: GSE93629
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93629
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by high throughput sequencing
Organism(s): Homo sapiens
Publication(s) associated with this dataset:- Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. 2017. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight 2(24):92821. doi:10.1172/jci.insight.92821 PMID:29263300 PMCID:PMC5752303