Superfund Research Program
The Role of Reactive Oxygen Species and the Microbiome in Toxicant Induced Liver Fibrosis
Project Leader: David A. Brenner
Co-Investigator: Rohit Loomba
Grant Number: P42ES010337
Funding Period: 2017-2023
Project-Specific Links
- Project Summary
Title: Blockade of lL17 signaling reverses alcohol-induced liver injury, and excessive alcohol drinking in mice.
Accession Number: GSE137228
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137228
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by high throughput sequencing
Organism(s): Mus musculus
Publication(s) associated with this dataset:- Xu J, Ma H, Liu X, Rosenthal SB, Baglieri J, Mccubbin R, Sun M, Koyama Y, Geoffroy C, Saijo K, Shang L, Nishio T, Maricic I, Kriefeldt M, Kusumanchi P, Roberts a, Zheng B, Kumar V, Zengler K, Pizzo D, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob G, Kisseleva T. 2020. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight doi:10.1172/jci.insight.131277 PMID:32051339 PMCID:PMC7098802