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University of California-San Diego: Dataset Details, ID=GSE137228

Superfund Research Program

The Role of Reactive Oxygen Species and the Microbiome in Toxicant Induced Liver Fibrosis

Project Leader: David A. Brenner
Co-Investigator: Rohit Loomba
Grant Number: P42ES010337
Funding Period: 2017-2023
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Title: Blockade of lL17 signaling reverses alcohol-induced liver injury, and excessive alcohol drinking in mice.

Accession Number: GSE137228

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137228

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by high throughput sequencing

Organism(s): Mus musculus

Publication(s) associated with this dataset:
  • Xu J, Ma H, Liu X, Rosenthal SB, Baglieri J, Mccubbin R, Sun M, Koyama Y, Geoffroy C, Saijo K, Shang L, Nishio T, Maricic I, Kriefeldt M, Kusumanchi P, Roberts a, Zheng B, Kumar V, Zengler K, Pizzo D, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob G, Kisseleva T. 2020. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight doi:10.1172/jci.insight.131277 PMID:32051339 PMCID:PMC7098802
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Last Reviewed: April 09, 2025