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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Pam Factor-Litvak

Superfund Research Program

Pam Factor-Litvak

Columbia University
Department of Epidemiology
Mailman School of Public Health
722 West 168 Street Room 1614
New York, New York 10032
Phone: 212-305-7851
Fax: 212-342-5169
Email: prf1@columbia.edu

Projects

Publications

2023

  • Spaur M, Bostick BC, Chillrud SN, Factor-Litvak P, Navas-Acien A, Nigra AE. 2023. Impact of lowering the US maximum contaminant level on arsenic exposure: Differences by race, region, and water arsenic in NHANES 2003-2014. Environ Pollut 333:122047. doi:10.1016/j.envpol.2023.122047 PMID:37331581
  • Welch BM, Keil AP, Buckley JP, Engel SM, James-Todd T, Zota AR, Alshawabkeh AN, Barrett ES, Bloom MS, Bush NR, Cordero JF, Dabelea D, Eskenazi B, Lanphear BP, Padmanabhan V, Sathyanarayana S, Swan SH, Aalborg J, Baird DD, Binder AM, Bradman A, Braun JM, Calafat AM, Cantonwine DE, Christenbury KE, Factor-Litvak P, Harley K, Hauser R, Herbstman JB, Hertz-Picciotto I, Holland NT, Jukic AM, McElrath TF, Meeker JD, Messerlian C, Michels KB, Newman RB, Nguyen RH, O'Brien KM, Rauh VA, Redmon B, Rich DQ, Rosen EM, Schmidt RJ, Sparks AE, Starling AP, Wang C, Watkins DJ, Weinberg CR, Weinberger B, Wenzel AG, Wilcox A, Yolton K, Zhang Y, Ferguson KK. 2023. Racial and ethnic disparities in phthalate exposure and preterm birth: A pooled study of sixteen U.S. cohorts. Environ Health Perspect 131(12):127015. doi:10.1289/ehp12831 PMID:38117586 PMCID:10732302

2022

  • Parvez F, Lauer FT, Factor-Litvak P, Islam T, Eunus M, Abu Horayara M, Rahman M, Sarwar G, Ahsan H, Graziano JH, Burchiel SW. 2022. Exposure to arsenic and level of Vitamin D influence the number of Th17 cells and production of IL-17A in human peripheral blood mononuclear cells in adults. PLoS One 17(4):e0266168. doi:10.1371/journal.pone.0266168 PMID:35404942 PMCID:PMC9000092
  • Saxena R, Gamble MV, Wasserman GA, Liu X, Parvez F, Navas-Acien A, Islam T, Factor-Litvak P, Uddin MN, Kioumourtzoglou M, Gibson EA, Shahriar H, Slavkovich VN, Ilievski V, Lolacono NJ, Balac O, Graziano JH. 2022. Mixed metals exposure and cognitive function in Bangladeshi adolescents. Ecotoxicol Environ Saf 232:113229. doi:10.1016/j.ecoenv.2022.113229 PMID:35131582
  • Welch BM, Keil AP, Buckley JP, Calafat AM, Christenbury KE, Engel SM, O'Brien KM, Rosen EM, James-Todd T, Zota AR, Ferguson KK, Alshawabkeh AN, Cordero JF, Meeker JD, Barrett ES, Bush NR, Nguyen RH, Sathyanarayana S, Swan SH, Cantonwine DE, Aalborg J, Dabelea D, Starling AP, Hauser R, Messerlian C, Zhang Y, Bradman A, Eskenazi B, Charley PH, Holland NT, Bloom MS, Newman RB, Wenzel AG, Braun JM, Lanphear BP, Yolton K, Factor-Litvak P, Herbstman JB, Rauh VA, Drobnis EZ, Sparks AE, Redmon JB, Wang C, Binder AM, Michels KB, Baird DD, Jukic AM, Weinberg CR, Wilcox AJ, Rich DQ, Weinberger B, Padmanabhan V, Watkins DJ, Hertz-Picciotto I, Schmidt RJ. 2022. Associations between prenatal urinary biomarkers of phthalate exposure and preterm birth: A pooled study at 16 US cohorts. JAMA Pediatr doi:10.1001/jamapediatrics.2022.2252 PMID:35816333 PMCID:PMC9274448

2020

  • Burchiel SW, Lauer FT, Factor-Litvak P, Liu X, Islam T, Eunus M, Abu Horayara M, Islam M, Rahman M, Ahmed A, Cremers S, Nandakumar R, Ahsan H, Olopade C, Graziano JH, Parvez F. 2020. Arsenic exposure associated T cell proliferation, smoking, and vitamin D in Bangladeshi men and women. PLoS One 15:13. doi:10.1371/journal.pone.0234965 PMID:32574193 PMCID:PMC7310686
  • Nigra AE, Chen Q, Chillrud SN, Wang L, Harvey DE, Mailloux BJ, Factor-Litvak P, Navas-Acien A. 2020. Inequalities in public water arsenic concentrations in counties and community water systems across the United States, 2006-2011. Environ Health Perspect 128(12):127001. doi:10.1289/EHP7313 PMID:33295795 PMCID:PMC7724967
  • Tinkelman NE, Spratlen MJ, Domingo-Relloso A, Tellez-Plaza M, Grau-Perez M, Francesconi KA, Goessler W, Howard BV, MacCluer J, North KE, Umans JG, Factor-Litvak P, Cole SA, Navas-Acien A. 2020. Associations of maternal arsenic exposure with adult fasting glucose and insulin resistance in the Strong Heart study and Strong Heart Family study. Environ Int 137:doi:10.1016/j.envint.2020.105531 PMID:32059145

2019

  • Burchiel SW, Lauer FT, Factor-Litvak P, Liu X, Santella RM, Islam T, Eunus M, Alam N, Islam T, Rahman M, Ahmed A, Ahsan H, Graziano JH, Parvez F. 2019. An increase in circulating B cells and B cell activation markers in peripheral blood is associated with cigarette smoking in a male cohort in Bangladesh. Toxicol Appl Pharmacol 384:114783. doi:10.1016/j.taap.2019.114783 PMID:31669812 PMCID:PMC6886671
  • Lauer FT, Parvez F, Factor-Litvak P, Liu X, Santella RM, Islam M, Eunus M, Alam N, Hasan R, Rahman M, Ahsan H, Graziano JH, Burchiel SW. 2019. Changes in human peripheral blood mononuclear cell (HPBMC) populations and T-cell subsets associated with arsenic and polycyclic aromatic hydrocarbon exposures in a Bangladesh cohort. PLoS One 14(7):e0220451. doi:10.1371/journal.pone.0220451 PMID:31365547 PMCID:PMC6668812
  • Parvez F, Lauer FT, Factor-Litvak P, Liu X, Santella RM, Islam T, Eunus M, Alam N, Sarwar G, Rahman M, Ahsan H, Graziano JH, Burchiel SW. 2019. Assessment of arsenic and polycyclic aromatic hydrocarbon (PAH) exposures on immune function among males in Bangladesh. PLoS One 14:doi:10.1371/journal.pone.0216662 PMID:31095595 PMCID:PMC6522035

2018

  • Wasserman GA, Liu X, Parvez F, Chen Y, Factor-Litvak P, Lolacono NJ, Levy D, Shahriar H, Uddin MN, Islam T, Lomax A, Saxena R, Gibson EA, Kioumourtzoglou M, Balac O, Sanchez TR, Kline JK, Santiago D, Ellis T, Graziano JH, van Geen AF. 2018. A cross-sectional study of water arsenic exposure and intellectual function in adolescence in Araihazar, Bangladesh. Environ Int 118:304-313. doi:10.1016/j.envint.2018.05.037 PMID:29933234

2016

  • Wasserman GA, Liu X, Parvez F, Factor-Litvak P, Kline JK, Siddique A, Shahriar H, Uddin MN, van Geen AF, Mey JL, Balac O, Graziano JH. 2016. Child intelligence and reductions in water arsenic and manganese: a two-year follow-up study in Bangladesh. Environ Health Perspect 124(7):1114-1120. doi:10.1289/ehp.1509974 PMID:26713676 PMCID:PMC4937860

2015

  • Khan K, Ahmed EB, Factor-Litvak P, Liu X, Siddique A, Wasserman GA, Slavkovich VN, Levy D, Mey JL, van Geen AF, Graziano JH. 2015. Evaluation of an elementary school-based educational intervention for reducing arsenic exposure in Bangladesh. Environ Health Perspect 123(12):1331-1336. doi:10.1289/ehp.1409462 PMID:25956010 PMCID:PMC4671245
  • Peters BA, Hall MN, Liu X, Parvez F, Sanchez TR, van Geen AF, Mey JL, Siddique A, Shahriar H, Uddin MN, Islam T, Balac O, Ilievski V, Factor-Litvak P, Graziano JH, Gamble MV. 2015. Folic acid and creatine as therapeutic approaches to lower blood arsenic: a randomized controlled trial. Environ Health Perspect 123(12):1294-1301. doi:10.1289/ehp.1409396 PMID:25978852 PMCID:PMC4671237

2014

  • Peters BA, Hall MN, Liu X, Neugut Y, Pilsner JR, Levy D, Ilievski V, Slavkovich VN, Islam T, Factor-Litvak P, Graziano JH, Gamble MV. 2014. Creatinine, arsenic metabolism, and renal function in an arsenic-exposed population in Bangladesh. PLoS One 9(12):e113760. doi:10.1371/journal.pone.0113760 PMID:25438247 PMCID:PMC4249915
  • Wasserman GA, Liu X, LoIacono NJ, Kline JK, Factor-Litvak P, van Geen AF, Mey JL, Levy D, Abramson R, Schwartz A, Graziano JH. 2014. A cross-sectional study of well water arsenic and child IQ in Maine schoolchildren. Environ Health 13:23. doi:10.1186/1476-069x-13-23 PMID:24684736 PMCID:PMC4104994

2013

2012

  • George CM, Khan K, Islam T, Singha A, Moon-Howard J, Factor-Litvak P, van Geen AF, Graziano JH. 2012. Approaches to increase arsenic awareness in Bangladesh: an evaluation of an arsenic education program. Health Educ Behav doi:10.1177/1090198112454735 PMID:22984214 PMCID:PMC3696588
  • George CM, van Geen AF, Slavkovich VN, Singha A, Levy D, Islam T, Ahmed KM, Moon-Howard J, Tarozzi A, Liu X, Factor-Litvak P, Graziano JH. 2012. A cluster-based randomized controlled trial promoting community participation in arsenic mitigation efforts in Bangladesh. Environ Health 11:41. doi:10.1186/1476-069x-11-41 PMID:22713347 PMCID:PMC3506475
  • Khan K, Wasserman GA, Liu X, Ahmed EB, Parvez F, Slavkovich VN, Levy D, Mey JL, van Geen AF, Graziano JH, Factor-Litvak P. 2012. Manganese exposure from drinking water and children's academic achievement. Neurotoxicology 33(1):91-97. doi:10.1016/j.neuro.2011.12.002 PMID:22182530 PMCID:PMC3282923
  • Pilsner JR, Hall MN, Liu X, Ilievski V, Slavkovich VN, Levy D, Factor-Litvak P, Yunus M, Rahman M, Graziano JH, Gamble MV. 2012. Influence of prenatal arsenic exposure and newborn sex on global methylation of cord blood DNA. PLoS One 7:doi:10.1371/journal.pone.0037147 PMID:22662134 PMCID:PMC3360698

2011

  • Khan K, Factor-Litvak P, Wasserman GA, Liu X, Ahmed EB, Parvez F, Slavkovich VN, Levy D, van Geen AF, Mey JL, Graziano JH. 2011. Manganese exposure from drinking water and children's classroom behavior in Bangladesh. Environ Health Perspect 119:1501-1506. doi:10.1289/ehp.1003397 PMID:21493178 PMCID:PMC3230445
  • Louis ED, Factor-Litvak P, Gerbin M, Slavkovich VN, Graziano JH, Jiang W, Zheng W. 2011. Blood harmane, blood lead, and severity of hand tremor: evidence of additive effects. Neurotoxicology 32:227-232. doi:10.1016/j.neuro.2010.12.002 PMID:21145352 PMCID:PMC3073713
  • Parvez F, Wasserman GA, Factor-Litvak P, Liu X, Slavkovich VN, Siddique A, Sultana R, Islam T, Levy D, Mey JL, van Geen AF, Khan K, Kline JK, Ahsan H, Graziano JH. 2011. Arsenic exposure and motor function among children in Bangladesh. Environ Health Perspect 119:1665-1670. doi:10.1289/ehp.1103548 PMID:21742576 PMCID:PMC3226503
  • Pilsner JR, Hall MN, Liu X, Ahsan H, Ilievski V, Slavkovich VN, Levy D, Factor-Litvak P, Graziano JH, Gamble MV. 2011. Associations of plasma selenium with arsenic and genomic methylation of leukocyte DNA in Bangladesh. Environ Health Perspect 119(1):113-118. doi:10.1289/ehp.1001937 PMID:21205583 PMCID:PMC3018489
  • Wasserman GA, Liu X, Parvez F, Factor-Litvak P, Ahsan H, Levy D, Kline JK, van Geen AF, Mey JL, Slavkovich VN, Siddique A, Islam T, Graziano JH. 2011. Arsenic and manganese exposure and children's intellectual function. Neurotoxicology 32(4):450-457. doi:10.1016/j.neuro.2011.03.009 PMID:21453724 PMCID:PMC4062913

2009

  • Hall M, Liu X, Slavkovich VN, Ilievski V, Pilsner JR, Alam S, Factor-Litvak P, Graziano JH, Gamble MV. 2009. Folate, cobalamin, cysteine, homocysteine, and arsenic metabolism among children in Bangladesh. Environ Health Perspect 117(5):825-831. doi:10.1289/ehp.0800164 PMID:19479028 PMCID:PMC2685848
  • Liu X, Slavkovich VN, Ilievski V, Mi Z, Alam S, Factor-Litvak P, Ahsan H, Graziano JH, Gamble MV, Hall MN. 2009. Influence of cobalamin on arsenic metabolism in Bangladesh. Environ Health Perspect 117(11):1724-1729. doi:10.1289/ehp.0900734 PMID:20049124 PMCID:PMC2801198
  • Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich VN, Levy D, Factor-Litvak P, Graziano JH, Gamble MV. 2009. Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions. Environ Health Perspect 117(2):254-260. doi:10.1289/ehp.11872 PMID:19270796 PMCID:PMC2649228

2007

  • Chen Y, Factor-Litvak P, Howe GR, Graziano JH, Brandt-Rauf PW, Parvez F, van Geen AF, Ahsan H. 2007. Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional study. Am J Epidemiol 165(5):541-552. PMID:17164464
  • Gamble MV, Liu X, Slavkovich VN, Pilsner JR, Ilievski V, Factor-Litvak P, Levy D, Alam S, Islam MN, Parvez F, Ahsan H, Graziano JH. 2007. Folic acid supplementation lowers blood arsenic. Am J Clin Nutr 86(4):1202-1209. PMID:17921403 PMCID:PMC2042963
  • Hafeman D, Factor-Litvak P, Cheng Z, van Geen AF, Ahsan H. 2007. Association between manganese exposure through drinking water and infant mortality in Bangladesh. Environ Health Perspect 115(7):1107-1112. doi:10.1289/ehp.10051 PMID:17637930 PMCID:PMC1913599
  • Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich VN, Levy D, Factor-Litvak P, Graziano JH, Gamble MV. 2007. Genomic methylation of peripheral blood leukocyte DMA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr 86(4):1179-1186. PMID:17921400
  • Wasserman GA, Liu X, Parvez F, Ahsan H, Factor-Litvak P, Kline JK, van Geen AF, Slavkovich VN, Lolacono NJ, Levy D, Cheng Z, Graziano JH. 2007. Water arsenic exposure and ntellectual function in six-year-old children in Araihazar, Bangladesh. Environ Health Perspect 115(2):285-289.

2006

  • Chen Y, Factor-Litvak P, Howe GR, Parvez F, Ahsan H. 2006. Nutritional influence on risk of high blood pressure in Bangladesh: a population-based cross-sectional study. Am J Clin Nutr 84(5):1224-1232. PMID:17093178
  • Gamble MV, Liu X, Ahsan H, Pilsner JR, Ilievski V, Slavkovich VN, Parvez F, Chen Y, Levy D, Factor-Litvak P, Graziano JH. 2006. Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh. Am J Clin Nutr 84(5):1093-1101. PMID:17093162 PMCID:PMC2046214
  • Gamble MV, Pilsner JR, Liu X, Ahsan H, Ilievski V, Slavkovich VN, Parvez F, Factor-Litvak P, Graziano JH. 2006. Methylation of arsenic and DNA: A double-blind, placebo controlled trial of folic acid supplementation in Gangladesh. In: Proceedings of the FASEB (Federation of American Societies) Summer Conferenence Folic Acid, B12 and One Carbon Metabolism, August 5-10. Indian Wells, CA.
  • Wasserman GA, Liu X, Parvez F, Ahsan H, Levy D, Factor-Litvak P, Kline JK, van Geen AF, Slavkovich VN, Lolacono NJ, Cheng Z, Zheng Y, Graziano JH. 2006. Water manganese exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect 114(1):124-129. PMID:16393669

2005

  • Gamble MV, Ahsan H, Factor-Litvak P, Ilievski V, Slavkovich VN, Parvez F, Graziano JH. 2005. Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh. Am J Clin Nutr 81(6):1372-1377. PMID:15941889 PMCID:PMC2204145
  • Gamble MV, Liu X, Ahsan H, Pilsner JR, Ilievski V, Slavkovich VN, Parvez F, Levy D, Factor-Litvak P, Graziano JH. 2005. Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh. Environ Health Perspect 113(12):1683-1688. PMID:16330347

2004

  • Wasserman GA, Liu X, Parvez F, Ahsan H, Factor-Litvak P, van Geen AF, Slavkovich VN, Lolacono NJ, Cheng Z, Hussain A, Momotaj H, Graziano JH. 2004. Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect 112(13):1329-1333. PMID:15345348 PMCID:PMC1247525

2003

  • Wasserman GA, Factor-Litvak P, Liu X, Todd AC, Kline JK, Slavkovich VN, Popovac D, Graziano JH. 2003. The relationship between blood lead, bone lead and child intelligence. Child Neuropsychology (Neuropsychology, Development and Cognition: Section C) 9(1):22-34. PMID:12815520
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