Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document

Your Environment. Your Health.

Person Details: Jack Bodwell

Superfund Research Program

Jack Bodwell

Dartmouth College
Department of Physiology
7700 Borwell, Room 750W
One Medical Center Drive
Lebanon, New Hampshire 03756-1000
Phone: 603-650-7734
Fax: 603-650-6130
Email: Jack.E.Bodwell@Dartmouth.Edu

Projects

Publications

2014

  • Gosse JA, Taylor VF, Jackson BP, Hamilton JW, Bodwell J. 2014. Monomethylated trivalent arsenic species disrupt steroid receptor interactions with their DNA response elements at non-cytotoxic cellular concentrations. J Appl Toxicol 34(5):498-505. doi:10.1002/jat.2898 PMID:23765520 PMCID:PMC3884051

2007

  • Bodwell J, Gosse JA, Hamilton JW, Davey JC. 2007. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicol Sci 98(1):75-86. doi:10.1093/toxsci/kfm013 PMID:17283378

2006

  • Bodwell J, Gosse JA, Nomikos AP, Hamilton JW. 2006. Arsenic disruption of steroid receptor gene activation: complex dose-response effects are shared by several steroid receptors. Chem Res Toxicol 19(12):1619-1629. doi:10.1021/tx060122q PMID:17173375 PMCID:PMC2556599

2004

  • Bodwell J, Kingsley LA, Hamilton JW. 2004. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chem Res Toxicol 17(8):1064-1076. PMID:15310238

2003

  • Hamilton JW, Bodwell J, Kingsley LA, Barnet CS, Davey JC. 2003. Arsenic alters hormone-mediated positive, but not negative, regulatory effects of steroid receptors. Toxicol Sci 72(S1):16.

2002

  • Hamilton JW, Bodwell J, Kaltreider RC, Davis AM, Davey JC, Kingsley LA, Lariviere JP. 2002. Arsenic is an endocrine disruptor, blocking hormone-mediated gene regulation by the estrogen and glucocorticoid receptors in vivo. Toxicol Sci 66(S1):85.
Back
to Top
Last Reviewed: April 09, 2025