Superfund Research Program
Marc G. Weisskopf
Harvard School of Public Health
665 Huntington Ave.
Bldg. 1
Suite 1402
Boston, Massachusetts 02215
Phone: 617-384-8872
Email: mweissko@hsph.harvard.edu
Projects
- Harvard School of Public Health: Metals, Critical Windows of Exposures, Epigenetics, and Late-Life Cognitive Function (2020-2025)
Publications
2024
- Bauer J, Punshon T, Barr M, Jackson BP, Weisskopf MG, Bidlack F, Coker M, Peacock JL, Karagas MR. 2024. Deciduous teeth from the New Hampshire birth cohort study: early life environmental and dietary predictors of dentin elements. Environ Res 256:doi:10.1016/j.envres.2024.119170 PMID:38768888
- Farmer J, Specht AJ, Punshon T, Jackson BP, Bidlack F, Bakalar C, Mukherjee R, Davis MJ, Steadman D, Weisskopf MG. 2024. Lead exposure across the life course and age at death. Sci Total Environ 927:doi:10.1016/j.scitotenv.2024.171975 PMID:38547974 PMCID:11069331
- Punshon T, Bauer J, Karagas MR, Coker M, Weisskopf MG, Mangano J, Bidlack F, Barr M, Jackson BP. 2024. Quantified retrospective biomonitoring of fetal and infant elemental exposure using LA-ICP-MS analysis of deciduous dentin in three contrasting human cohorts. J Expo Sci Environ Epidemiol doi:10.1038/s41370-024-00652-3 PMID:38347123
- Qiu X, Robert A, McAlaine K, Quan L, Mangano J, Weisskopf MG. 2024. Early-life participation in cognitively stimulating activities and risk of depression and anxiety in late life. Psychol Med 54(5):962-970. doi:10.1017/s0033291723002702 PMID:37706289 PMCID:10937330
2023
- Leung M, Rowland ST, Coull BA, Modest AM, Hacker MR, Schwartz J, Kioumourtzoglou M, Weisskopf MG, Wilson A. 2023. Bias amplification and variance inflation in distributed lag models using low-spatial-resolution data. Am J Epidemiol 192(4):644-657. doi:10.1093/aje/kwac220 PMID:36562713 PMCID:PMC10404064
- Mork D, Kioumourtzoglou M, Weisskopf MG, Coull BA, Wilson A. 2023. Heterogeneous distributed lag models to estimate personalized effects of maternal exposures to air pollution. J Am Stat Assoc doi:10.1080/01621459.2023.2258595
2022
- Comfort N, Wu H, De Hoff P, Vuppala A, Vokonas PS, Spiro A, Weisskopf MG, Coull BA, Laurent LC, Baccarelli A, Schwartz J. 2022. Extracellular microRNA and cognitive function in a prospective cohort of older men: The Veterans Affairs Normative Aging Study. Aging-US 14(17):6859-6886. doi:10.18632/aging.204268 PMID:36069796 PMCID:9512498
- Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Korrick SA. 2022. Prenatal exposure to chemical mixtures and working memory among adolescents. Environ Res 205:doi:10.1016/j.envres.2021.112436 PMID:34843721 PMCID:PMC8760169
- Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Korrick SA. 2022. The association of prenatal manganese exposure with problem-solving skills and its mediation by the building blocks of executive function. Neurotoxicology 92:191-199. doi:10.1016/j.neuro.2022.08.009 PMID:35995271
2021
- Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Zemplenyi M, Korrick SA. 2021. Prenatal exposure to chemical mixtures and inhibition among adolescents. Toxics 9(11):311. doi:10.3390/toxics9110311 PMID:34822702 PMCID:PMC8619850
- Specht AJ, Zhang X, Young AS, Nguyen VT, Christiani DC, Ceballos DM, Allen JG, Weuve J, Nie LH, Weisskopf MG. 2021. Validation of in vivo toenail measurements of manganese and mercury using a portable X-ray fluorescence device. J Expo Sci Environ Epidemiol doi:10.1038/s41370-021-00358-w PMID:34211112 (ahead of print)
2020
- Kponee-Shovein K, Weisskopf MG, Grashow R, Rotem RS, Coull BA, Schnaas L, del Carmen Hernandez-Chavez M, Sanchez BN, Peterson K, Hu H, Tellez-Rojo M. 2020. Estimating the causal effect of prenatal lead exposure on prepulse inhibition deficits in children and adolescents. Neurotoxicology 78:116-126. doi:10.1016/j.neuro.2020.02.013 PMID:32126243
2019
- Kponee-Shovein K, Grashow R, Coull BA, Tellez-Rojo M, Schnaas L, del Carmen Hernandez-Chavez M, Sanchez BN, Peterson K, Hu H, Hernandez-Avila M, Weisskopf MG. 2019. Socio-demographic predictors of prepulse inhibition: A prospective study in children and adolescents from Mexico City. Biol Psychol 145:8-16. doi:10.1016/j.biopsycho.2019.03.003 PMID:30940478
2018
- Vieira VM, Hansen J, Gredal O, Weisskopf MG. 2018. Spatial analyses of ALS incidence in Denmark over three decades. Amyotroph Lateral Scler Frontotemporal Degener 19:275-284. doi:10.1080/21678421.2018.1432658 PMID:29383960
- Weisskopf MG, Seals RM, Webster TF. 2018. Bias amplification in epidemiologic analysis of exposure to mixtures. Environ Health Perspect 126:8. doi:10.1289/ehp2450 PMID:29624292
2017
- Hoffman K, Weisskopf MG, Roberts AL, Raz R, Hart JE, Lyall K, Hoffman E, Laden F, Vieira VM. 2017. Geographic patterns of autism spectrum disorder among children of Nurses’ Health Study II women. Am J Epidemiol 186:834–842. doi:10.1093/aje/kwx158 PMID:28525627
2015
- Ji JS, Power MC, Sparrow D, Spiro, III A, Hu H, Louis ED, Weisskopf MG. 2015. Lead exposure and tremor among older men: the VA normative aging study. Environ Health Perspect 123(5):445-450. doi:10.1289/ehp.1408535 PMID:25633720 PMCID:PMC4421770
2014
- Grashow R, Zhang J, Fang SC, Weisskopf MG, Christiani DC, Kile ML, Cavallari JM. 2014. Inverse association between toenail arsenic and body mass index in a population of welders. Environ Res 131:131-133. doi:10.1016/j.envres.2014.03.010 PMID:24721130 PMCID:PMC4035809
2013
- Eum K, Wang FT, Schwartz J, Hersh CP, Kelsey KT, Wright RO, Spiro, III A, Sparrow D, Hu H, Weisskopf MG. 2013. Modifying roles of glutathione S-transferase polymorphisms on the association between cumulative lead exposure and cognitive function. Neurotoxicology 39C:65-71. doi:10.1016/j.neuro.2013.08.002 PMID:23958642 PMCID:PMC3844089
- Grashow R, Spiro, III A, Taylor KM, Newton K, Shrairman R, Landau A, Sparrow D, Hu H, Weisskopf MG. 2013. Cumulative lead exposure in community-dwelling adults and fine motor function: Comparing standard and novel tasks in the VA Normative Aging Study. Neurotoxicology 35:154-161. doi:10.1016/j.neuro.2013.01.005 PMID:23370289 PMCID:PMC3602137
- Power MC, Weisskopf MG, Alexeeff SE, Wright RO, Coull BA, Spiro, III A, Schwartz J. 2013. Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study. Environ Health 12:16. doi:10.1186/1476-069x-12-16 PMID:23413885 PMCID:PMC3599892
2011
- Eum K, Nie LH, Schwartz J, Vokonas PS, Sparrow D, Hu H, Weisskopf MG. 2011. Prospective cohort study of lead exposure and electrocardiographic conduction disturbances in the Department of Veterans Affairs Normative Aging Study. Environ Health Perspect 119:940-944. doi:10.1289/ehp.1003279 PMID:21414889 PMCID:PMC3223010
- Peters J, Kubzansky LD, Ikeda A, Spiro, III A, Wright RO, Weisskopf MG, Kim D, Sparrow D, Nie LH, Hu H, Schwartz J. 2011. Childhood and adult socioeconomic position, cumulative lead levels, and pessimism in later life: the VA Normative Aging Study. Am J Epidemiol 174:1345-1353. doi:10.1093/aje/kwr269 PMID:22071587 PMCID:PMC3276297
- Peters JL, Kubzansky LD, Ikeda A, Fang SC, Sparrow D, Weisskopf MG, Wright RO, Vokonas PS, Hu H, Schwartz J. 2011. Lead concentrations in relation to multiple biomarkers of cardiovascular disease: the Normative Aging Study. Environ Health Perspect 120:361-366. doi:10.1289/ehp.1103467 PMID:22142875 PMCID:PMC3295335
- Power MC, Weisskopf MG, Coull BA, Spiro, III A, Schwartz J. 2011. Traffic-related air pollution and cognitive function in a cohort of older men. Environ Health Perspect 119:682-687. doi:10.1289/ehp.1002767 PMID:21172758 PMCID:PMC3094421
2010
- Hoffman K, Webster TF, Weisskopf MG, Weinberg JM, Vieira VM. 2010. Exposure to polyfluoroalkyl chemicals and attention deficit/hyperactivity disorder in U.S. children 12-15 years of age. Environ Health Perspect 118:1762-1767. doi:10.1289/ehp.1001898 PMID:20551004 PMCID:PMC3002197
- Park S, Elmarsafawy S, Mukherjee B, Spiro, III A, Vokonas PS, Nie H, Weisskopf MG, Schwartz J, Hu H. 2010. Cumulative lead exposure and age-related hearing loss: The VA Normative Aging Study. Hear Res 269(1-2):48-55. doi:10.1016/j.heares.2010.07.004 PMID:20638461 PMCID:PMC2934752
- Zhang A, Park S, Wright RO, Weisskopf MG, Mukherjee B, Nie H, Sparrow D, Hu H. 2010. HFE H63D polymorphism as a modifier of the effect of cumulative lead exposure on pulse pressure: The Normative Aging Study. Environ Health Perspect 118:1261-1266. doi:10.1289/ehp.1002251 PMID:20478760 PMCID:PMC2944087
2009
- Park SK, Hu H, Wright RO, Schwartz J, Cheng Y, Sparrow D, Vokonas PS, Weisskopf MG. 2009. Iron metabolism genes, low-level lead exposure, and QT interval. Environ Health Perspect 117(1):80-85. doi:10.1289/ehp.11559 PMID:19165391 PMCID:PMC2627870
- Weisskopf MG, Jain N, Nie H, Sparrow D, Vokonas PS, Schwartz J, Hu H. 2009. A prospective study of bone lead concentration and death from all causes, cardiovascular diseases, and cancer in the Department of Veterans Affairs Normative Aging Study. Circulation 120(12):1056-1064. doi:10.1161/CIRCULATIONAHA.108.827121 PMID:19738141 PMCID:PMC2760410
2008
- Lampe BJ, Park S, Robins T, Mukherjee B, Litonjua A, Amarasiriwardena CJ, Weisskopf MG, Sparrow D, Hu H. 2008. Association between 24-hour urinary cadmium and pulmonary function among community-exposed men: the VA Normative Aging Study. Environ Health Perspect 116(9):1226-1230. doi:10.1289/ehp.11265 PMID:18795167 PMCID:PMC2535626
- Rajan P, Kelsey KT, Schwartz J, Bellinger DC, Weuve J, Spiro, III A, Sparrow D, Smith TJ, Nie H, Weisskopf MG, Hu H, Wright RO. 2008. Interaction of the delta-aminolevulinic acid dehydratase polymorphism and lead burden on cognitive function: the VA normative aging study. J Occup Environ Med 50(9):1053-1061. doi:10.1097/JOM.0b013e3181792463 PMID:18784554 PMCID:PMC3664949
2007
- Shih RA, Hu H, Weisskopf MG, Schwartz BS. 2007. Cumulative lead dose and cognitive function in adults: a review of studies that measured both blood lead and bone lead. Environ Health Perspect 115(3):483-92. PMID:17431502
- Weisskopf MG, Proctor SP, Wright RO, Schwartz J, Spiro, III A, Sparrow D, Nie H, Hu H. 2007. Cumulative lead exposure and cognitive performance among elderly men. Epidemiology 18(1):59-66. PMID:17130688
2006
- Park SK, Schwartz J, Weisskopf MG, Vokonas PS, Wright RO, Coull BA, Nie H, Hu H. 2006. Low-level lead exposure, metabolic syndrome, and heart rate variability: the VA Normative Aging Study. Environ Health Perspect 114(11):1718-24. PMID:17107858
2004
- Weisskopf MG, Hu H, Mulkern RV, Wright RO, Aro A, Oliveira S, White RF. 2004. Cognitive deficits and magnetic resonance spectroscopy in adult monozygotic twins with lead poisoning. Environ Health Perspect 112(5):620-625. PMID:15064171
- Weisskopf MG, Wright RO, Schwartz J, Spiro, III A, Sparrow D, Aro A, Hu H. 2004. Cumulative lead exposure and change in cognition among elderly men: the VA Normative Aging Study. Am J Epidemiol 15(4):S147-S147.