Superfund Research Program
Prabhat C. Goswami
University of Iowa
Radiation Research Laboratory
B180 ML
Iowa City, Iowa 52242
Phone: 319-384-4666
Email: prabhat-goswami@uiowa.edu
Projects
- ORA-01403: no data found: Oxidative Stress and PCB Exposure in Mammalian Cells ()
Publications
2016
- Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC. 2016. Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes. Arch Toxicol 90(2):319-332. doi:10.1007/s00204-014-1407-3 PMID:25417049 PMCID:PMC4441874
2015
- Xiao W, Goswami PC. 2015. Down-regulation of peroxisome proliferator activated receptor γ coactivator 1α induces oxidative stress and toxicity of 1-(4-Chlorophenyl)-benzo-2,5-quinone in HaCaT human keratinocytes. Toxicol In Vitro 29(7):1332-1338. doi:10.1016/j.tiv.2015.05.009 PMID:26004620 PMCID:PMC4553100
- Xiao W, Son J, Vorrink SU, Domann FE, Goswami PC. 2015. Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicol Lett 233(3):258-266. doi:10.1016/j.toxlet.2015.02.005 PMID:25668756 PMCID:PMC4341842
2014
- Sarsour EH, Kalen AL, Goswami PC. 2014. Manganese superoxide dismutase regulates a redox cycle within the cell cycle. Antioxid Redox Signal 20(10):1618-1627. doi:10.1089/ars.2013.5303 PMID:23590434 PMCID:PMC3942678
- Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE. 2014. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Exp Toxicol Pathol 66(8):377-382. doi:10.1016/j.etp.2014.05.005 PMID:24916446 PMCID:PMC4143452
2013
- Eckers JC, Kalen AL, Xiao W, Sarsour EH, Goswami PC. 2013. Selenoprotein P inhibits radiation-induced late reactive oxygen species accumulation and normal cell injury. Int J Radiat Oncol Biol Phys 87(3):619-625. doi:10.1016/j.ijrobp.2013.06.2063 PMID:24074935 PMCID:PMC3787541
- Xiao W, Zhu Y, Sarsour EH, Kalen AL, Aykin-Burns N, Spitz DR, Goswami PC. 2013. Selenoprotein P regulates 1-(4-Chlorophenyl)-benzo-2, 5-quinone-induced oxidative stress and toxicity in human keratinocytes. Free Radic Biol Med 65:70-77. doi:10.1016/j.freeradbiomed.2013.06.010 PMID:23770201 PMCID:PMC3830697
2012
- Chaudhuri L, Nicholson AM, Kalen AL, Goswami PC. 2012. Preferential selection of MnSOD transcripts in proliferating normal and cancer cells. Oncogene 31:1207-1216. doi:10.1038/onc.2011.325 PMID:21804600 PMCID:PMC3208126
- Sarsour EH, Kalen AL, Xiao Z, Veenstra TD, Chaudhuri L, Venkataraman S, Reigan P, Buettner GR, Goswami PC. 2012. Manganese superoxide dismutase regulates a metabolic switch during the Mammalian Cell Cycle. Cancer Res 72:3807-3816. doi:10.1158/0008-5472.CAN-11-1063 PMID:22710435 PMCID:PMC3429130
2011
- Sarsour EH, Kumar MG, Kalen AL, Goswami M, Buettner GR, Goswami PC. 2011. MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. Age (Dordr) 34(1):95-109. doi:10.1007/s11357-011-9223-7 PMID:21384152 PMCID:PMC3260369
2010
- Chaudhuri L, Sarsour EH, Goswami PC. 2010. 2-(4-chlorophenyl)benzo-1,4-quinone induced ROS-signaling inhibits proliferation in human non-malignant prostate epithelial cells. Environ Int 36(8):924-930. doi:10.1016/j.envint.2010.01.001 PMID:20163859 PMCID:PMC2888671
- Chaudhuri L, Sarsour EH, Kalen AL, Aykin-Burns N, Spitz DR, Goswami PC. 2010. Polychlorinated biphenyl induced ROS signaling delays the entry of quiescent human breast epithelial cells into the proliferative cycle. Free Radic Biol Med 49(1):40-49. doi:10.1016/j.freeradbiomed.2010.03.012 PMID:20307652 PMCID:PMC2875331
- Venkatesha VA, Kalen AL, Sarsour EH, Goswami PC. 2010. PCB-153 exposure coordinates cell cycle progression and cellular metabolism in human mammary epithelial cells. Toxicol Lett 196(2):110-116. doi:10.1016/j.toxlet.2010.04.005 PMID:20394812 PMCID:PMC2891036
2008
- Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler H, Goswami PC. 2008. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med 45(8):1094-1102. doi:10.1016/j.freeradbiomed.2008.07.007 PMID:18691649 PMCID:PMC2614346