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Your Environment. Your Health.

Person Details: Qiang Zhang

Superfund Research Program

Qiang Zhang

The Hamner Institutes for Health Sciences
1518 Clifton Road, NE
Grace Frum Rollins Building, Floor 04
Atlanta, Georgia 30322
Phone: 404-727-0154







  • Zhang Q, Li J, Middleton A, Bhattacharya S, Conolly RB. 2018. Bridging the data gap from in vitro toxicity testing to chemical safety assessment through computational modeling. Front Public Health 6:261. doi:10.3389/fpubh.2018.00261 PMID:30255008 PMCID:PMC6141783
  • Zhou J, Zhang Q, Henriquez J, Crawford RB, Kaminski NE. 2018. Lymphocyte-specific protein tyrosine kinase (LCK) is involved in the aryl hydrocarbon receptor-mediated impairment of immunoglobulin secretion in human primary B cells. Toxicol Sci 165(2):322-334. doi:10.1093/toxsci/kfy133 PMID:29860352


  • Zhang Q, Bhattacharya S, Conolly RB, Clewell H, Andersen ME. 2014. Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses. Environ Health Perspect 122(12):1261-1270. doi:10.1289/ehp.1408244 PMID:25117432 PMCID:PMC4256703



  • Bhattacharya S, Zhang Q, Andersen ME. 2011. Double-negative feedback loops as a common design motif in the transcriptional networks regulating cell fate. International Journal of Design Engineering 4:41-57. doi:10.1504/IJDE.2011.041408
  • Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME. 2011. Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. PLoS One 6(6):doi:10.1371/journal.pone.0020887 PMID:21701582 PMCID:PMC3118802 (Completed with ARRA Funds)


  • Andersen ME, Zhang Q, Bhattacharya S. 2010. Modeling Gene and Protein Expression - Nested Motifs in Cellular and Tissue Response Networks. Chapter 10 in: Quantitative Modeling in Toxicology. John Wiley & Sons, Hoboken, NJ.
  • Bhattacharya S, Conolly RB, Kaminski NE, Thomas RS, Andersen ME, Zhang Q. 2010. A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci 115(1):51-65. doi:10.1093/toxsci/kfq035 PMID:20123757 PMCID:PMC2855357
  • Bhattacharya S, Zhang Q, Andersen ME. 2010. Bistable Signaling Motifs and Cell Fate Decisions. Chapter 8 in: Quantitative Modeling in Toxicology. John Wiley & Sons, Hoboken, NJ.
  • Zhang Q, Bhattacharya S, Andersen ME, Conolly RB. 2010. Computational systems biology and dose-response modeling in relation to new directions in toxicity testing. J Environ Sci Health B 13(2-4):253-76. doi:10.1080/10937404.2010.483943 PMID:20574901
  • Zhang Q, Bhattacharya S, Kline DE, Crawford RB, Thomas RS, Kaminski NE, Andersen ME, Conolly RB. 2010. Stochastic modeling of B lymphocyte terminal differentiation and its suppression by dioxin. BMC Syst Biol 4:40. doi:10.1186/1752-0509-4-40 PMID:20359356 PMCID:PMC2859749
  • Zhang Q, Bhattacharya S, Woods CG, Andersen ME. 2010. Ultrasensitive Response Motifs in Biochemical Networks. Chapter 9 in: Quantitative Modeling in Toxicology. John Wiley & Sons, Hoboken, NJ. pp.199-218.
  • Zhang Q, Pi J, Woods CG, Andersen ME. 2010. A systems biology perspective on Nrf2-mediated antioxidant response. Toxicol Appl Pharmacol 244(1):84-97. doi:10.1016/j.taap.2009.08.018 PMID:19716833 PMCID:PMC2837757



  • Zhang Q, Thomas RS, Kaminski NE, Conolly RB, Andersen ME. 2006. Computational modeling of TCDD disruption of B-cell terminal differentiation. In: Superfund Basic Research Program Annual Meeting, December 11-12. La Jolla, CA.


  • Spiegelstein O, Mitchell LE, Merriweather MY, Wicker NJ, Zhang Q, Lammer EJ, Finnell RH. 2004. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn 231(1):221-231. doi:10.1002/dvdy.20107 PMID:15305303
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