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Your Environment. Your Health.

Person Details: David C. Bellinger

Superfund Research Program

David C. Bellinger

Harvard School of Public Health
Children's Hospital
Farley Basement Box 127
300 Longwood Ave
Boston, Massachusetts 02115
Phone: 617-355-6565
Fax: 617-384-8856


Hazardous Waste Sites


  • Invalid project

Mexico City

  • Invalid project

Tar Creek (Ottawa County)

  • Invalid project



  • Devick K, Bobb JF, Mazumdar M, Claus Henn B, Bellinger DC, Wright RO, Williams PL, Coull BA, Valeri L, Christiani DC. 2022. Bayesian kernel machine regression-causal mediation analysis. Stat Med doi:10.1002/sim.9255 PMID:34993981
  • Liu J, Deng W, Lee JJ, Lin PD, Valeri L, Christiani DC, Bellinger DC, Wright RO, Mazumdar M, Coull BA. 2022. A cross-validated ensemble approach to robust hypothesis testing of continuous nonlinear interactions: applications of nutrition-environment studies. J Am Stat Assoc 117(538):561-573. doi:10.1080/01621459.2021.1962889 PMID:36310839 PMCID:PMC9611147
  • Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Korrick SA. 2022. Prenatal exposure to chemical mixtures and working memory among adolescents. Environ Res 205:doi:10.1016/j.envres.2021.112436 PMID:34843721 PMCID:PMC8760169
  • Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Korrick SA. 2022. The association of prenatal manganese exposure with problem-solving skills and its mediation by the building blocks of executive function. Neurotoxicology 92:191-199. doi:10.1016/j.neuro.2022.08.009 PMID:35995271
  • Rokoff LB, Shoaff JR, Coull BA, Enlow MB, Bellinger DC, Korrick SA. 2022. Prenatal exposure to a mixture of organochlorines and metals and internalizing symptoms in childhood and adolescence. Environ Res 208:doi:10.1016/j.envres.2022.112701 PMID:35016863 PMCID:PMC8917058


  • Laue HE, Karagas MR, Coker M, Bellinger DC, Baker E, Korrick SA, Madan J. 2021. Sex-specific relationships of the infant microbiome and early-childhood behavioral outcomes. Pediatric Research doi:10.1038/s41390-021-01785-z PMID:34732816 (ahead of print)
  • Liu J, Lee JJ, Lin PD, Valeri L, Christiani DC, Bellinger DC, Wright RO, Mazumdar M, Coull BA. 2021. A cross-validated Ensemble Approach to Robust Hypothesis Testing of Continuous Nonlinear Interactions: Application to Nutrition-Environment Studies. J Am Stat Assoc 13:
  • Oppenheimer AV, Bellinger DC, Coull BA, Weisskopf MG, Zemplenyi M, Korrick SA. 2021. Prenatal exposure to chemical mixtures and inhibition among adolescents. Toxics 9(11):311. doi:10.3390/toxics9110311 PMID:34822702 PMCID:PMC8619850


  • Antonelli J, Mazumdar M, Bellinger DC, Christiani DC, Wright RO, Coull BA. 2020. Estimating the health effects of environmental mixtures using bayesian semiparametric regression and sparsity inducing priors. Annals of Applied Statistics 14:257-275. doi:10.1214/19-aoas1307
  • Gleason K, Valeri L, Shankar AH, Obrycki JF, Sharif OI, Mostofa G, Quamruzzaman Q, Wright RO, Christiani DC, Bellinger DC, Mazumdar M. 2020. Stunting and lead: using causal mediation analysis to better understand how environmental lead exposure affects cognitive outcomes in children. J Neurodev Disord 12:39. doi:10.1186/s11689-020-09346-x PMID:33327931


  • Liu J, Lee JJ, Lynn P, Valeri L, Christiani DC, Bellinger DC, Wright RO, Mazumdar M, Coull BA. 2019. A Cross-validated Ensemble Approach to Robust Hypothesis Testing of Continuous Nonlinear Interactions: Application to Nutrition-Environment Studies. J Am Stat Assoc
  • Shaffer RM, Sellers SP, Baker MG, de Buen Kalman R, Frostad J, Suter MK, Anenberg SC, Balbus J, Basu N, Bellinger DC, Birnbaum LS, Brauer M, Cohen A, Ebi KL, Fuller R, Grandjean P, Hess JJ, Kogevinas M, Kumar P, Landrigan PJ, Lanphear BP, London SJ, Rooney AA, Stanaway JD, Trasande L, Walker K, Hu H. 2019. Improving and expanding estimates of the global burden of disease due to environmental health risk factors. Environ Health Perspect 127:doi:10.1289/EHP5496 PMID:31626566 PMCID:PMC6867191
  • Xu J, Hu H, Wright RJ, Schnaas L, Bellinger DC, Park S, Wright RO, Tellez-Rojo M. 2019. Prenatal lead exposure modifies the association of maternal self-esteem with child adaptive ability. Int J Hyg Environ Health 222(1):68-75. doi:10.1016/j.ijheh.2018.08.005 PMID:30146178


  • Lee JJ, Valeri L, Kapur K, Hasan O, Quamruzzaman Q, Wright RO, Bellinger DC, Christiani DC, Mazumdar M. 2018. Growth parameters at birth mediate the relationship between prenatal manganese exposure and cognitive test scores among a cohort of 2-to 3-year-old Bangladeshi children. Int J Epidemiol 47(4):1169-1179. doi:10.1093/ije/dyy069 PMID:29733356
  • Sun R, Wang Z, Henn BC, Su L, Lu Q, Lin X, Wright RO, Bellinger DC, Kile ML, Mazumdar M, Tellez-Rojo MM, Schnaas L, Christiani DC. 2018. Identification of novel loci associated with infant cognitive ability. Mol Psychiatry PMID:30120420
  • Woo MK, Young ES, Mostofa G, Afroz S, Hasan OS, Quamruzzaman Q, Bellinger DC, Christiani DC, Mazumdar M. 2018. Lead in air in Bangladesh: Exposure in a rural community with elevated blood lead concentrations among young children. Int J Environ Res Public Health 15(9):1947. doi:10.3390/ijerph15091947 PMID:30200642


  • Henn BC, Bellinger DC, Hopkins MR, Coull BA, Ettinger AS, Jim R, Hatley EL, Christiani DC, Wright RO. 2017. Maternal and cord blood manganese concentrations and early childhood neurodevelopment among residents near a mining-impacted superfund site. Environ Health Perspect 125:9. doi:10.1289/ehp925 PMID:28665786
  • Tamayo y Ortiz M, Tellez-Rojo MM, Trejo-Valdivia B, Schnaas L, Osorio-Valencia E, Coull BA, Bellinger DC, Wright RJ, Wright RO. 2017. Maternal stress modifies the effect of exposure to lead during pregnancy and 24-month old children's neurodevelopment. Environ Int 98:191-197. doi:10.1016/j.envint.2016.11.005 PMID:27865525 PMCID:PMC5221478
  • Valeri L, Mazumdar M, Bobb JF, Henn BC, Rodrigues EG, Sharif OI, Kile ML, Quamruzzaman Q, Afroz S, Golam M, Amarasiriwardena C, Bellinger DC, Christiani DC, Coull BA, Wright RO. 2017. Effect of prenatal exposure to metal mixtures on neurodevelopmental outcomes at 20-40 months of age: Evidence from Rural Bangladesh. Environ Health Perspect 125:11. doi:10.1289/ehp614 PMID:28669934
  • Wang Z, Henn BC, Wang C, Wei Y, Li S, Sun R, Chen H, Wagner PJ, Lu Q, Lin X, Wright RO, Bellinger DC, Kile ML, Mazumdar M, Tellez-Rojo M, Schnaas L, Christiani DC. 2017. Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment. Environ Health 16:81. doi:10.1186/s12940-017-0288-3 PMID:28754176 PMCID:PMC5534076


  • Claus Henn B, Ettinger AS, Hopkins MR, Jim R, Amarasiriwardena CJ, Christiani DC, Coull BA, Bellinger DC, Wright RO. 2016. Prenatal arsenic exposure and birth outcomes among a population residing near a mining-related Superfund site. Environ Health Perspect 124(8):1308-1315. doi:10.1289/ehp.1510070 PMID:26859631 PMCID:PMC4977047
  • Gleason K, Valeri L, Shankar AH, Hasan O, Quamruzzaman Q, Rodrigues EG, Christiani DC, Wright RO, Bellinger DC, Mazumdar M. 2016. Stunting is associated with blood lead concentration among Bangladeshi children aged 2-3 years. Environ Health 15(1):103. doi:10.1186/s12940-016-0190-4 PMID:27809911 PMCID:PMC5096334
  • Rodrigues EG, Bellinger DC, Valeri L, Hasan OS, Quamruzzaman Q, Golam M, Kile ML, Christiani DC, Wright RO, Mazumdar M. 2016. Neurodevelopmental outcomes among 2- to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water. Environ Health 15:44. doi:10.1186/s12940-016-0127-y PMID:26968381 PMCID:PMC4788832
  • Stroustrup A, Hsu H, Svensson K, Schnaas L, Cantoral A, Solano-Gonzalez M, Torres-Calapiz M, Amarasiriwardena CJ, Bellinger DC, Coull BA, Tellez-Rojo MM, Wright RO, Wright RJ. 2016. Toddler temperament and prenatal exposure to lead and maternal depression. Environ Health 15(1):71. doi:10.1186/s12940-016-0147-7 PMID:27312840 PMCID:PMC4910201


  • Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel R, Gray K, Ha E, Junien C, Karagas MR, Kawamoto T, Lawrence BP, Perera F, Prins GS, Rosenfeld CS, Sherr DH, Sly PD, Suk WA, Sun Q, Toppari J, van den Hazel P, Walker CL, Heindel JJ. 2015. Life-long implications of developmental exposure to environmental stressors: new perspectives. Endocrinology 156(10):3408-3415. doi:10.1210/EN.2015-1350 PMID:26241067 PMCID:PMC4588822
  • Verner M, Hart JE, Sagiv SK, Bellinger DC, Altshul LM, Korrick SA. 2015. Measured prenatal and estimated postnatal levels of polychlorinated biphenyls (PCBs) and ADHD-related behaviors in 8-year-old children. Environ Health Perspect 123(9):888-894. doi:10.1289/ehp.1408084 PMID:25769180 PMCID:PMC4559949


  • Fortenberry GZ, Meeker JD, Sanchez BN, Barr DB, Panuwet P, Bellinger DC, Schnaas L, Solano-Gonzalez M, Ettinger AS, Hernandez-Avila M, Hu H, Tellez-Rojo MM. 2014. Urinary 3,5,6-trichloro-2-pyridinol (TCPY) in pregnant women from Mexico City: distribution, temporal variability, and relationship with child attention and hyperactivity. Int J Hyg Environ Health 217(2-3):405-412. doi:10.1016/j.ijheh.2013.07.018 PMID:24001412 PMCID:PMC3946926
  • Fortenberry GZ, Meeker JD, Sanchez BN, Bellinger DC, Peterson KE, Schnaas L, Solano-Gonzalez M, Ettinger AS, Hernandez-Avila M, Hu H, Tellez-Rojo MM. 2014. Paraoxonase I polymorphisms and attention/hyperactivity in school-age children from Mexico City, Mexico. Environ Res 132:342-349. doi:10.1016/j.envres.2014.04.010 PMID:24834831
  • Gleason K, Shine JP, Shobnam N, Rokoff LB, Suchanda HS, Hasan OS, Mostofa G, Amarasiriwardena CJ, Quamruzzaman Q, Rahman M, Kile ML, Bellinger DC, Christiani DC, Wright RO, Mazumdar M. 2014. Contaminated turmeric is a potential source of lead exposure for children in rural Bangladesh. J Environ Public Health 2014:730636. doi:10.1155/2014/730636 PMID:25214856 PMCID:PMC4158309
  • Karwowski MP, Just AC, Bellinger DC, Jim R, Hatley EL, Ettinger AS, Hu H, Wright RO. 2014. Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study. Environ Health 13:77. doi:10.1186/1476-069X-13-77 PMID:25287020 PMCID:PMC4271345
  • Orenstein ST, Thurston SW, Bellinger DC, Schwartz J, Amarasiriwardena CJ, Altshul LM, Korrick SA. 2014. Prenatal organochlorine and methylmercury exposure and memory and learning in school-age children in communities near the New Bedford Harbor Superfund Site, Massachusetts. Environ Health Perspect 122:1253-1259. doi:10.1289/ehp.1307804 PMID:25062363 PMCID:PMC4216164



  • Bellinger DC. 2012. A strategy for comparing the contributions of environmental chemicals and other risk factors to neurodevelopment of children. Environ Health Perspect 120(4):501-507. doi:10.1289/ehp.1104170 PMID:22182676 PMCID:PMC3339460
  • Bellinger DC. 2012. Comparing the population neurodevelopmental burdens associated with children's exposures to environmental chemicals and other risk factors. Neurotoxicology 33(4):641-643. doi:10.1016/j.neuro.2012.04.003 PMID:22525934
  • Braun JM, Hoffman E, Schwartz J, Sanchez BN, Schnaas L, Mercado-Garcia A, Solano-Gonzalez M, Bellinger DC, Lanphear BP, Hu H, Tellez-Rojo MM, Wright RO, Hernandez-Avila M. 2012. Assessing windows of susceptibility to lead-induced cognitive deficits in Mexican children. Neurotoxicology 33:1040-1047. doi:10.1016/j.neuro.2012.04.022 PMID:22579785 PMCID:PMC3576696
  • Braun JM, Lucchini R, Bellinger DC, Hoffman E, Nazzaro M, Smith D, Wright RO. 2012. Predictors of virtual radial arm maze performance in adolescent Italian children. Neurotoxicology 33(5):1203-1211. doi:10.1016/j.neuro.2012.06.012 PMID:22771383 PMCID:PMC3470779
  • Ciesielski T, Weuve J, Bellinger DC, Schwartz J, Lanphear BP, Wright RO. 2012. Cadmium exposure and neurodevelopmental outcomes in U.S. children. Environ Health Perspect 120(5):758-763. doi:10.1289/ehp.1104152 PMID:22289429 PMCID:PMC3346779
  • Roels HA, Bowler RM, Kim Y, Claus Henn B, Mergler D, Hoet P, Gocheva VV, Bellinger DC, Wright RO, Harris MG, Chang Y, Bouchard MF, Riojas-Rodriguez H, Menezes-Filho JA, Tellez-Rojo MM. 2012. Manganese exposure and cognitive deficits: a growing concern for manganese neurotoxicity. Neurotoxicology 33(4):872-880. doi:10.1016/j.neuro.2012.03.009 PMID:22498092 PMCID:PMC3839941
  • Sagiv SK, Thurston SW, Bellinger DC, Altshul LM, Korrick SA. 2012. Neuropsychological measures of attention and impulse control among 8-year old children exposed prenatally to organochlorines. Environ Health Perspect 120:904-909. doi:10.1289/ehp.1104372 PMID:22357172 PMCID:PMC3385436
  • Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena CJ, Korrick SA. 2012. Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder–related behavior in children. Arch Pediatr Adolesc Med 166:1123-1131. doi:10.1001/archpediatrics.2012.1286 PMID:23044994 PMCID:PMC3991460


  • Claus Henn B, Wright RO, Schnaas L, Ettinger AS, Schwartz J, Lamadrid-Figueroa H, Hernandez-Avila M, Amarasiriwardena CJ, Hu H, Bellinger DC, Tellez-Rojo MM. 2011. Associations of early childhood manganese and lead coexposure with neurodevelopment. Environ Health Perspect 120:126-131. doi:10.1289/ehp.1003300 PMID:21885384 PMCID:PMC3261931
  • Kordas K, Ettinger AS, Bellinger DC, Schnaas L, Tellez-Rojo MM, Hernandez-Avila M, Hu H, Wright RO. 2011. A dopamine receptor (DRD2) but not dopamine transporter (DAT1) gene polymorphism is associated with neurocognitive development of Mexican preschool children with lead exposure. J Pediatr 159:638-643. doi:10.1016/j.jpeds.2011.03.043 PMID:21592505 PMCID:PMC3158955
  • Nie LH, Wright RO, Bellinger DC, Hussain J, Amarasiriwardena CJ, Chettle DR, Pejovic-Milic A, Woolf AD, Shannon MW. 2011. Blood lead levels and cumulative blood lead index (CBLI) as predictors of late neurodevelopment in lead poisoned children. Biomarkers 16(6):517-24. doi:10.3109/1354750X.2011.604133 PMID:21827276 PMCID:PMC3229913
  • Palaniappan K, Roy A, Balakrishnan K, Gopalakrishnan L, Mukherjee B, Hu H, Bellinger DC. 2011. Lead exposure and visual-motor abilities in children from Chennai, India. Neurotoxicology 32:465-470. doi:10.1016/j.neuro.2011.03.011 PMID:21510976 PMCID:PMC3115626
  • Roy A, Hu H, Bellinger DC, Mukherjee B, Modali R, Nasaruddin K, Schwartz J, Wright RO, Ettinger AS, Palaniapan K, Balakrishnan K. 2011. Hemoglobin, lead exposure, and intelligence quotient: effect modification by the DRD2 Taq IA polymorphism. Environ Health Perspect 119(1):144-149. doi:10.1289/ehp.0901878 PMID:21205584 PMCID:PMC3018494
  • Schwartz J, Bellinger DC, Glass T. 2011. Expanding the scope of environmental risk assessment to better include differential vulnerability and susceptibility. Am J Public Health 101Suppl1:S88-93. doi:10.2105/AJPH.2011.300268 PMID:22021314 PMCID:PMC3222479
  • Schwartz J, Bellinger DC, Glass T. 2011. Expanding the scope of risk assessment: methods of studying differential vulnerability and susceptibility. Am J Public Health 101Suppl1:S102-9. doi:10.2105/AJPH.2011.300367 PMID:22021313 PMCID:PMC3222483
  • Schwartz J, Bellinger DC, Glass T. 2011. Exploring potential sources of differential variability and susceptibility in risk from environmental hazards to expand the scope of risk assessment. Am J Public Health 101Suppl1:S94-S101. doi:10.2105/AJPH.2011.300272 PMID:22021315 PMCID:PMC3222466


  • Claus Henn B, Ettinger AS, Schwartz J, Tellez-Rojo MM, Lamadrid-Figueroa H, Hernandez-Avila M, Schnaas L, Amarasiriwardena CJ, Bellinger DC, Hu H, Wright RO. 2010. Early postnatal blood manganese levels and children's neurodevelopment. Epidemiology 21(4):433-439. doi:10.1097/EDE.0b013e3181df8e52 PMID:20549838 PMCID:PMC3127440
  • Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul LM, Korrick SA. 2010. Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol 171(5):593-601. doi:10.1093/aje/kwp427 PMID:20106937 PMCID:PMC2842227


  • Roy A, Hu H, Bellinger DC, Palaniapan K, Wright RO, Schwartz J, Balakrishnan K. 2009. Predictors of blood lead in children in Chennai, India (2005-2006). Int J Occup Environ Health 15(4):351-9. PMID:19886345


  • Ettinger AS, Hernandez-Avila M, Schwartz J, Tellez-Rojo MM, Lamadrid-Figueroa H, Bellinger DC, Hu H, Wright RO, Hopkins MR. 2008. Variants in iron metabolism genes predict higher blood lead levels in young children. Environ Health Perspect 116(9):1261-1266. doi:10.1289/ehp.11233 PMID:18795173 PMCID:PMC2535632
  • Rajan P, Kelsey KT, Schwartz J, Bellinger DC, Weuve J, Spiro, III A, Sparrow D, Smith TJ, Nie H, Weisskopf MG, Hu H, Wright RO. 2008. Interaction of the delta-aminolevulinic acid dehydratase polymorphism and lead burden on cognitive function: the VA normative aging study. J Occup Environ Med 50(9):1053-1061. doi:10.1097/JOM.0b013e3181792463 PMID:18784554 PMCID:PMC3664949
  • Surkan PJ, Schnaas L, Wright RJ, Tellez-Rojo MM, Lamadrid-Figueroa H, Hu H, Hernandez-Avila M, Bellinger DC, Schwartz J, Perroni E, Wright RO. 2008. Maternal self-esteem, exposure to lead, and child neurodevelopment. Neurotoxicology 29(2):278-285. doi:10.1016/j.neuro.2007.11.006 PMID:18261800 PMCID:PMC2495770


  • Hu H, Tellez-Rojo MM, Bellinger DC, Smith DR, Ettinger AS, Lamadrid-Figueroa H, Schwartz J, Schnaas L, Mercado-Garcia A, Hernandez-Avila M. 2006. Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development. Environ Health Perspect 114(11):1730-1735. PMID:17107860 PMCID:PMC1665421
  • Weuve J, Kelsey KT, Schwartz J, Bellinger DC, Wright RO, Rajan P, Spiro, III A, Sparrow D, Aro A, Hu H. 2006. Delta-aminolevulinic acid dehydratase polymorphism and the relation between low level lead exposure and the Mini-Mental Status Examination in older men: the Normative Aging Study. Occup Environ Med 63(11):746-753. PMID:16757504


  • Ettinger AS, Tellez-Rojo MM, Amarasiriwardena CJ, Bellinger DC, Peterson KE, Schwartz J, Hu H, Hernandez-Avila M. 2004. Effect of breast milk lead on infant blood lead levels at 1 month of age. Environ Health Perspect 112(14):1381-1385. PMID:15471729


  • Wright RO, Hu H, Silverman EK, Tsaih S, Schwartz J, Bellinger DC, Weiss ST, Palazuelos E, Hernandez-Avila M. 2003. Apolipoprotein E genotype predicts 24-month Bayley scales infant development score. Pediatric Research 54(6):819-825. PMID:12930912


  • Gomaa A, Hu H, Bellinger DC, Schwartz J, Schnaas L, Gonzalez-Cossio T, Peterson KE, Aro A, Hernandez-Avila M. 2002. Maternal bone lead as an independent risk factor for fetal neurotoxicity: a prospective study. Pediatrics 110:110-118. PMID:12093955
  • Woolf AD, Wright RO, Amarasiriwardena CJ, Bellinger DC. 2002. A child with chronic manganese exposure from drinking water. Environ Health Perspect 110:613-616. PMID:12055054


  • Kim R, Hu H, Rotnitzky A, Bellinger DC, Needleman HL. 1996. Longitudinal relationship between dentin lead levels in childhood and bone lead levels in young adulthood. Arch Environ Health 51:375-382. PMID:8896387


  • Kim R, Hu H, Rotnitzky A, Bellinger DC, Needleman HL. 1995. Chronic lead exposure and physical growth parameters in a 13-year follow-up study. Environ Health Perspect 103:952-957.
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