Superfund Research Program
Frederick E. Domann
University of Iowa
B180 Medical Laboratories
Iowa City, Iowa 52242
Email: Frederick-domann@uiowa.edu
Projects
- University of Iowa: Oxidative Stress and PCB Exposure in Mammalian Cells (2006 - 2015)
Publications
2016
- Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC. 2016. Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes. Arch Toxicol 90(2):319-332. doi:10.1007/s00204-014-1407-3 PMID:25417049 PMCID:PMC4441874
2015
- Xiao W, Son J, Vorrink SU, Domann FE, Goswami PC. 2015. Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicol Lett 233(3):258-266. doi:10.1016/j.toxlet.2015.02.005 PMID:25668756 PMCID:PMC4341842
2014
- Hallberg AR, Vorrink SU, Hudachek DR, Cramer-Morales K, Milhem MM, Cornell RA, Domann FE. 2014. Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma. Epigenetics 9(12):1641-1647. doi:10.4161/15592294.2014.988062 PMID:25625848 PMCID:PMC4622677
- Shaughnessy DT, McAllister KA, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli A, Begley T, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL. 2014. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect 122(12):1271-1278. doi:10.1289/ehp.1408418 PMID:25127496 PMCID:PMC4256704
- Vorrink SU, Domann FE. 2014. Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node. Chem Biol Interact 218:82-88. doi:10.1016/j.cbi.2014.05.001 PMID:24824450 PMCID:PMC4091760
- Vorrink SU, Hudachek DR, Domann FE. 2014. Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). Int J Mol Sci 15(8):13916-13931. doi:10.3390/ijms150813916 PMID:25116688 PMCID:PMC4159831
- Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE. 2014. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Exp Toxicol Pathol 66(8):377-382. doi:10.1016/j.etp.2014.05.005 PMID:24916446 PMCID:PMC4143452
- Vorrink SU, Severson PL, Kulak MV, Futscher BW, Domann FE. 2014. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicol Appl Pharmacol 274(3):408-416. doi:10.1016/j.taap.2013.12.002 PMID:24355420 PMCID:PMC3919493
2005
- Bredfeldt TG, Billings KE, Zheng XH, Mash EA, Domann FE, Lau SS, Sens DA, Gandolfi A. 2005. Arsenite and monomethyl arsonous acid-induced toxicity ion human urothelial cells. Environ Health Perspect 84(S1):31.