Superfund Research Program

J. Bruce German

University of California-Davis
Department of Food Science and Technology
212 Food Sci & Tech
One Shields Avenue
Davis, California 95616-8598
Phone: 530-752-1486
Email: jbgerman@ucdavis.edu

Projects

• University of California-Davis: Analytical Chemistry (1995-2023)
• University of California-Davis: Integrated Response to Toxic Perturbation (2000-2010)

Publications

2019

• Gan J, Siegel JB, German JB. 2019. Molecular annotation of food: Towards personalized diet and precision health. Trends Food Sci Technol 21:doi:10.1016/j.tifs.2019.07.016 PMID:33299266 PMCID:PMC7723349 (accepted for publication)

2018

• Bever C, Nording ML, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD. 2018. Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere 203:467-473. doi:10.1016/j.chemosphere.2018.03.186 PMID:29635158 PMCID:PMC5915298

2016

• Cajka T, Davis R, Austin KJ, Newman JW, German JB, Smilowitz JT, Fiehn O. 2016. Using a lipidomics approach for nutritional phenotyping in response to a test meal containing gamma-linolenic acid. Metabolomics 12:127. doi:10.1007/s11306-016-1075-9
• Shih P, Yang J, Morisseau C, German JB, Zeeland AA, Armando AM, Quehenberger O, Bergen AW, Magistretti P, Berrettini W, Halmi KA, Schork N, Hammock BD, Kaye W. 2016. Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa. Mol Psychiatry 21(4):537-546. doi:10.1038/mp.2015.26 PMID:25824304 PMCID:PMC4591075

2015

• Berthelot CC, Kamita SG, Sacchi R, Yang J, Nording ML, Georgi K, Karbowski CH, German JB, Weiss RH, Hogg RJ, Hammock BD, Zivkovic AM. 2015. Changes in PTGS1 and ALOX12 gene expression in peripheral blood mononuclear cells are associated with changes in arachidonic acid, oxylipins, and oxylipin/fatty acid ratios in response to omega-3 fatty acid supplementation. PLoS One 10(12):e0144996. doi:10.1371/journal.pone.0144996 PMID:26672987 PMCID:PMC4681469

2014

• Mehra R, Barile D, Marotta M, Lebrilla CB, Chu C, German JB. 2014. Novel high-molecular weight fucosylated milk oligosaccharides identified in dairy streams. PLoS One 9:doi:10.1371/journal.pone.0096040 PMID:24810963 PMCID:PMC4014476

2013

• Nording ML, Yang J, Georgi K, Karbowski CH, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. 2013. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One 8:e76575. doi:10.1371/journal.pone.0076575 PMID:24204640 PMCID:PMC3811983
• Smilowitz JT, Zivkovic AM, Wan YY, Watkins SM, Nording M, Hammock BD, German JB. 2013. Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res 57(8):1319-1335. doi:10.1002/mnfr.201200808 PMID:23818328 PMCID:PMC3806310

2012

• Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. 2012. Serum oxylipin profiles in lgA nephropathy patients reflect kidney functional alterations. Metabolomics 8(6):1102-1113. doi:10.1007/s11306-012-0417-5 PMID:23833568 PMCID:PMC3700377

2011

• Barile D, Guinard J, Meyrand M, German JB. 2011. Examining bioactive components of mil Complex oligosaccharides (Part 1). Agro Food Ind Hi Tech 22:34-36.
• Dallas DC, Martin WF, Strum JS, Zivkovic AM, Smilowitz JT, Underwood MA, Affolter M, Lebrilla CB, German JB. 2011. N-linked glycan profiling of mature human milk by high-performance microfluidic chip liquid chromatography time-of-flight tandem mass spectrometry. J Agric Food Chem 59(8):4255-4263. doi:10.1021/jf104681p PMID:21384928 PMCID:PMC4422756

2010

• Argov-Argaman N, Smilowitz JT, Bricarello DA, Barboza M, Lerno L, Froehlich JW, Lee H, Zivkovic AM, Lemay DG, Freeman S, Lebrilla CB, Parikh AN, German JB. 2010. Lactosomes: Structural and compositional classification of unique nanometer-sized protein lipid particles of human milk. J Agric Food Chem 58(21):11234-11242. doi:10.1021/jf102495s PMID:20925428 PMCID:PMC3039697
• Barile D, Marotta M, Chu CR, Mehra R, Grimm R, Lebrilla CB, German JB. 2010. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. J Dairy Sci 93(9):3940-3949. doi:10.3168/jds.2010-3156 PMID:20723667 PMCID:PMC3951277
• Froehlich JW, Dodds ED, Barboza M, McJimpsey EL, Seipert RR, Francis J, An HJ, Freeman S, German JB, Lebrilla CB. 2010. Glycoprotein expression in human milk during lactation. J Agric Food Chem 58(10):6440-6448. doi:10.1021/jf100112x PMID:20415418 PMCID:PMC2882031

2009

• Lemay DG, Lynn DJ, Neville MC, Casey TM, Rincon G, Kriventseva EV, Barris WC, Hinrichs AS, Molenaar AJ, Pollard KS, Maqbool NJ, Singh K, Murney R, Zdobnov EM, Tellam RL, Medrano JF, German JB, Rijnkels M. 2009. The bovine lactation genome: insights into the evolution of mammalian milk. Genome Biol Evol 10(4):R43. doi:10.1186/gb-2009-10-4-r43 PMID:19393040 PMCID:PMC2688934
• Luria A, Morisseau C, Tsai H, Yang J, Inceoglu B, De Taeye B, Wiest MM, German JB, Hammock BD, Watkins SM. 2009. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. Am J Physiol Endocrinol Metab 297(2):E375-E383. doi:10.1152/ajpendo.00131.2009 PMID:19458064 PMCID:PMC2724109

2008

• Destaillats F, German JB, Chardigny J, Malpuech-Brugère C, Moulin J, Bauman DE, Lock AL, Barbano DM, Mensink RP, Bezelgues J, Chaumont P, Combe N, Cristiani I, Joffre F, Dionisi F, Boirie Y, Sébédio J. 2008. Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study. Am J Clin Nutr 87(3):558-566. PMID:18326592
• Seipert RR, Barboza M, Ninonuevo M, LoCascio R, Freeman SP, German JB, Lebrilla CB. 2008. Analysis and quantitation of fructooligosaccharides using matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem 80(1):159-165. doi:10.1021/ac7017298 PMID:18044961

2007

• German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM. 2007. Lipidomics and lipid profiling in metabolomics. Curr Opin Lipidol 18(1):66-71. doi:10.1097/MOL.0b013e328012d911 PMID:17218835
• German JB, Lebrilla CB, Dodds ED. 2007. Enabling MALDI-FTICR-MS/MS for high-performance proteomics through combination of infrared and collisional activation. Anal Chem 79(24):9547-9556. doi:10.1021/ac701763t PMID:18001128
• German JB, Lemay DG, Zivkovic AM. 2007. Building the bridges to bioinformatics in nutrition research. Am J Clin Nutr 86(5):1261-1269. PMID:17991634
• Hillyard SL, German JB. 2007. Non-essential dietary factors: from test tube to lifespan. Journal of the Science of Food and Agriculture 87(10):1802-1805. doi:10.1002/jsfa.2912
• Lemay DG, German JB, Lange MC. 2007. A multi-ontology framework to guide agriculture and food towards diet and health. Journal of the Science of Food and Agriculture 87(8):1427-1434. doi:10.1002/jsfa.2832
• Lemay DG, Neville MC, Rudolph MC, Pollard KS, German JB. 2007. Gene regulatory networks in lactation: identification of global principles using bioinformatics. BMC Syst Biol 1:56. PMID:18039394
• Ward RE, Milady N, Mills DA, Lebrilla CB, German JB. 2007. In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria. Mol Nutr Food Res 51(11):1398-1405. doi:10.1002/mnfr.200700150 PMID:17966141

2005

• German JB, Hammock BD, Watkins SM. 2005. Metabolomics: building on a century of biochemistry to guide human health. Metabolomics 1(1):3-9. PMID:16680201

2002

• Stanton B, Watkins SM, German JB, Lasley BL. 2002. Effect of estrogen and 2,3,7,8-tetrachlorodibenzo-rho-dioxin (TCDD) on plasma fatty acids of immature male chickens (Gallus domesticus). Comp Biochem Physiol C Toxicol Pharmacol 132(2):129-142. PMID:12106890

2001

• Stanton B, Watkins SM, German JB, Lasley BL. 2001. Interaction of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with hepatic fatty acid synthesis and metabolism of male chickens (Gallus domesticus). Comp Biochem Physiol C Toxicol Pharmacol 129(2):137-150. PMID:11423386
• Watkins SM, Hammock BD, Newman JW, German JB. 2001. Individual metabolism should guide agriculture toward foods for improved health and nutrition. Am J Clin Nutr 74(3):283-286. PMID:11522549

1996

• Bruenner BA, Jones AD, German JB. 1996. Simultaneous determination of multiple aldehydes in biological tissues and fluids using gas chromatography/stable isotope dilution mass spectrometry. Anal Biochem 241(2):212-219. PMID:8921190

1995

• Bruenner BA, Jones AD, German JB. 1995. Direct characterization of protein adducts of the lipid peroxidation product 4-hydroxy-2-nonenal using electrospray mass spectrometry. Chem Res Toxicol 8(4):552-559. PMID:7548735