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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Andrew J. Morris

Superfund Research Program

Andrew J. Morris

University of Kentucky
347 BBSRB
741 South Limestone
Lexington, Kentucky 40536-0200
Phone: 859-323-3749
Fax: 859-381-5953
Email: a.j.morris@uky.edu

Projects

Publications

2022

  • Petriello MC, Mottaleb MA, Serio TC, Balyan B, Cave MC, Birnbaum LS, Morris AJ. 2022. Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Community Health Surveys (ACHS I and ACHS II). Environ Int 158:106907. doi:10.1016/j.envint.2021.106907 PMID:34763231

2021

  • Deng P, Valentino, T, Flythe MD, Moseley HN, Leachman J, Morris AJ, Hennig B. 2021. Untargeted stable isotope probing of the gut microbiota metabolome using (13)C-labeled dietary fibers. J Proteome Res 20:doi:10.1021/acs.jproteome.1c00124 PMID:33830777
  • Mottaleb MA, Ding QX, Pennell KG, Haynes E, Morris AJ. 2021. Direct injection analysis of per and polyfluoroalkyl substances in surface and drinking water by sample filtration and liquid chromatography-tandem mass spectrometry. J Chromatogr A 1653:5. doi:10.1016/j.chroma.2021.462426 PMID:34352431

2020

  • Deng P, Hoffman JB, Petriello MC, Wang C, Li X, Kraemer MP, Morris AJ, Hennig B. 2020. Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice. J Lipid Res 61:45-53. doi:10.1194/jlr.RA119000346 PMID:31604806 PMCID:PMC6939596
  • Deng P, Wang C, Wahlang B, Sexton T, Morris AJ, Hennig B. 2020. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice. Toxicol Appl Pharmacol 409:115301. doi:10.1016/j.taap.2020.115301 PMID:33096110 PMCID:PMC7725976
  • Eke J, Banks L, Mottaleb MA, Morris AJ, Tsyusko OV, Escobar I. 2020. Dual-Functional Phosphorene Nanocomposite Membranes for the Treatment of Perfluorinated Water: An Investigation of Perfluorooctanoic Acid Removal via Filtration Combined with Ultraviolet Irradiation or Oxygenation. Membranes 11:doi:10.3390/membranes11010018 PMID:33375603
  • Guo Y, Ye Q, Deng P, Cao Y, He D, Zhou Z, Wang C, Zahtseva YY, Schwartz CE, Lee EY, Evers BM, Morris AJ, Liu S, She Q. 2020. Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression. Nat Commun 11:doi:10.1038/s41467-020-17067-x PMID:32591507 PMCID:PMC7320137
  • Hoffman JB, Petriello MC, Morris AJ, Mottaleb MA, Sui Y, Zhou C, Deng P, Wang C, Hennig B. 2020. Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice. Environ Pollut 261:114183. doi:10.1016/j.envpol.2020.114183 PMID:32105967 PMCID:PMC7220843
  • Mottaleb MA, Petriello MC, Morris AJ. 2020. High-throughput UHPLC-MS/MS measurement of per- and poly-fluorinated alkyl substances in human serum. J Anal Toxicol 44(4):339-347. doi:10.1093/jat/bkz097 PMID:31776573 PMCID:PMC7299301

2019

  • Deng P, Barney J, Petriello MC, Morris AJ, Wahlang B, Hennig B. 2019. Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction. Chemosphere 217:140-149. doi:10.1016/j.chemosphere.2018.10.196 PMID:30415113 PMCID:PMC6626632
  • Deng P, Li X, Petriello MC, Wang C, Morris AJ, Hennig B. 2019. Application of metabolomics to characterize environmental pollutant toxicity and disease risks. Rev Environ Health 34(3):251-259. doi:10.1515/reveh-2019-0030 PMID:31408434 PMCID:PMC6915040
  • Hardesty JE, Wahlang B, Falkner KC, Shi H, Jin J, Zhou Y, Wilkey D, Merchant ML, Watson C, Feng W, Morris AJ, Hennig B, Prough RA, Cave MC. 2019. Proteomic analysis reveals novel mechanisms by which polychlorinated biphenyls compromise the liver promoting diet-induced steatohepatitis. J Proteome Res 18(4):1582-1594. doi:10.1021/acs.jproteome.8b00886 PMID:30807179 PMCID:PMC7059562
  • Jackson E, Thatcher SE, Larian N, English V, Soman S, Morris AJ, Weng J, Stromberg AJ, Swanson HI, Pearson KJ, Cassis LA. 2019. Effects of aryl hydrocarbon receptor deficiency on PCB-77-induced impairment of glucose homeostasis during weight loss in male and female obese mice. Environ Health Perspect 127(7):doi:10.1289/EHP4133 PMID:31306034 PMCID:PMC6794491
  • Larian N, Ensor M, Thatcher SE, English V, Morris AJ, Stromberg AJ, Cassis LA. 2019. Pseudomonas aeruginosa-derived pyocyanin reduces adipocyte differentiation, body weight, and fat mass as mechanisms contributing to septic cachexia. Food Chem Toxicol 130:219-230. doi:10.1016/j.fct.2019.05.012 PMID:31078726 PMCID:PMC6557674

2018

  • Petriello MC, Brandon JA, Hoffman JB, Wang C, Tripathi H, Abdel-Latif A, Ye X, Li X, Yang L, Lee EY, Soman S, Barney J, Wahlang B, Hennig B, Morris AJ. 2018. Dioxin-like PCB 126 increases systemic inflammation and accelerates atherosclerosis in lean LDL receptor-deficient mice. Toxicol Sci 162(2):548-558. doi:10.1093/toxsci/kfx275 PMID:29216392 PMCID:PMC5888982
  • Petriello MC, Charnigo RJ, Sunkara M, Soman S, Pavuk M, Birnbaum LS, Morris AJ, Hennig B. 2018. Relationship between serum trimethylamine N-oxide and exposure to dioxin-like pollutants. Environ Res 162:211-218. doi:10.1016/j.envres.2018.01.007 PMID:29353125 PMCID:PMC5811317
  • Petriello MC, Hoffman JB, Vsevolozhskaya O, Morris AJ, Hennig B. 2018. Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis. Environ Pollut 242(A):1022-1032. doi:10.1016/j.envpol.2018.07.039 PMID:30373033 PMCID:PMC6211811

2017

2016

  • Keune W, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink R, Perrakis A. 2016. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun 7:11248. doi:10.1038/ncomms11248 PMID:27075612 PMCID:PMC4834639
  • Murphy MO, Petriello MC, Han S, Sunkara M, Morris AJ, Esser K, Hennig B. 2016. Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int 23(3):2201-2211. doi:10.1007/s11356-014-4062-6 PMID:25586614 PMCID:PMC4503535
  • Petriello MC, Hoffman JB, Sunkara M, Wahlang B, Perkins JT, Morris AJ, Hennig B. 2016. Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors. J Nutr Biochem 33:145-153. doi:10.1016/j.jnutbio.2016.03.016 PMID:27155921 PMCID:PMC4893916

2015

  • Baker NA, Shoemaker R, English V, Larian N, Sunkara M, Morris AJ, Walker M, Yiannikouris F, Cassis LA. 2015. Effects of adipocyte aryl hydrocarbon receptor deficiency on PCB-induced disruption of glucose homeostasis in lean and obese mice. Environ Health Perspect 123(10):944-950. doi:10.1289/ehp.1408594 PMID:25734695 PMCID:PMC4590748
  • Deng J, Coy D, Zhang W, Sunkara M, Morris AJ, Wang C, Chaiswing L, St Clair D, Vore M, Jungsuwadee P. 2015. Elevated glutathione is not sufficient to protect against doxorubicin-induced nuclear damage in heart in multidrug resistance-associated protein 1 (Mrp1/Abcc1) null mice. J Pharmacol Exp Ther 355(2):272-279. doi:10.1124/jpet.115.225490 PMID:26354996 PMCID:PMC4613962
  • Zhang W, Deng J, Sunkara M, Morris AJ, Wang C, St Clair D, Vore M. 2015. Loss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice. J Pharmacol Exp Ther 355(2):280-287. doi:10.1124/jpet.115.225581 PMID:26354995 PMCID:PMC4613956

2014

2013

  • Baker NA, English V, Sunkara M, Morris AJ, Pearson KJ, Cassis LA. 2013. Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes. J Nutr Biochem 24(12):2168-2174. doi:10.1016/j.jnutbio.2013.08.009 PMID:24231106 PMCID:PMC4066417
  • Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg AJ, Sunkara M, Morris AJ, Swanson HI, Cassis LA. 2013. Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect 121:105-110. doi:10.1289/ehp.1205421 PMID:23099484 PMCID:PMC3553436

2012

2011

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