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Person Details: James Zach Hilt

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Superfund Research Program

James Zach Hilt

University of Kentucky
177 F. Paul Anderson Tower
Lexington, Kentucky 40506-0503
Phone: 859-257-9844



Hazardous Waste Sites

Rockwell International Site

  • University of Kentucky: Biomimetic Magnetic Nanocomposites as a Platform Technology for the Capture and Sensing of PCBs




  • Baldridge KC, Edmonds K, Dziubla TD, Hilt JZ, Dutch RE, Bhattacharyya D. 2022. Demonstration of hollow fiber membrane-based enclosed space air remediation for capture of an aerosolized synthetic SARS-CoV-2 mimic and pseudovirus particles. ACS ES&T Eng 2(2):doi:10.1021/acsestengg.1c00369
  • Frazar EM, Smith A, Dziubla TD, Hilt JZ. 2022. Thermoresponsive cationic polymers: PFAS binding performance under variable pH, temperature and comonomer composition. Gels 8(10):668. doi:10.3390/gels8100668 PMID:36286169 PMCID:PMC9602350
  • Gutierrez AM, Leniz-Pizarro F, Wang X, Dziubla TD, Hilt JZ. 2022. Effect of atom transfer radical polymerization reaction time on PCB binding capacities of styrene-CMA/QMA core-shell iron oxide nanoparticles. Mater Sci Eng B-Adv Funct Solid-State Mater 277:115577. doi:10.1016/j.mseb.2021.115577
  • Paul P, Edmonds K, Baldridge KC, Bhattacharyya D, Dziubla TD, Dutch RE, Hilt JZ. 2022. Enhanced inactivation of pseudoparticles containing SARS-CoV-2 protein using magnetic nanoparticles and an alternating magnetic field. ACS Appl Bio Mater doi:10.1021/acsabm.2c00522 PMID:36314574


  • Gutierrez AM, Frazar EM, Klaus MV, Paul P, Hilt JZ. 2021. Hydrogels and hydrogel nanocomposites: Enhancing healthcare through human and environmental treatment. Adv Healthc Mater doi:10.1002/adhm.202101820 PMID:34811960
  • Savage DT, Briot N, Hilt JZ, Dziubla TD. 2021. On the swelling behavior of poly(N-Isopropylacrylamide) hydrogels exposed to perfluoroalkyl acids. J Polym Sci A Polym Chem 59(4):289-299. doi:10.1002/pol.20200805 PMID:34859243 PMCID:PMC8631585
  • Savage DT, Hilt JZ, Dziubla TD. 2021. Assessing the perfluoroalkyl acid-induced swelling of Forster resonance energy transfer-capable poly(N-isopropylacrylamide) microgels. Soft Matter 10:doi:10.1039/d1sm00985k PMID:34661226 PMCID:PMC8889493
  • Savage DT, Hilt JZ, Dziubla TD. 2021. Leveraging the thermoresponsiveness of fluorinated poly(N-isopropylacrylamide) copolymers as a sensing tool for perfluorooctane sulfonate. Analyst doi:10.1039/d1an00144b PMID:33928975
  • Savage DT, Hilt JZ, Dziubla TD. 2021. Leveraging the thermoresponsiveness of fluorinated poly(N-isopropylacrylamide) copolymers as a sensing tool for perfluorooctane sulfonate. Analyst 11:doi:10.1039/D1AN00144B
  • Shah RA, Runge T, Ostertag TW, Tang S, Dziubla TD, Hilt JZ. 2021. Development of temperature-responsive polymeric gels with physical crosslinking due to intermolecular pi-pi interactions. Polym Int


  • Gutierrez AM, Bhandari R, Weng J, Stromberg AJ, Dziubla TD, Hilt JZ. 2020. Synthesis of magnetic nanocomposite microparticles for binding of chlorinated organics in contaminated water sources. J Appl Polym Sci 137(37):49109. doi:10.1002/app.49109 PMID:34305166 PMCID:PMC8300995
  • Shah RA, Frazar EM, Hilt JZ. 2020. Recent developments in stimuli responsive nanomaterials and their bionanotechnology applications. Curr Opin Chem Eng 30:103-111. doi:10.1016/j.coche.2020.08.007 PMID:34307003 PMCID:PMC8300877
  • Shah RA, Ostertag TW, Tang S, Dziubla TD, Hilt JZ. 2020. Development of biphenyl monomers and associated crosslinked polymers with intramolecular pi-pi interactions. J Appl Polym Sci 12:doi:10.1002/app.50257


  • Ahmad I, Weng J, Stromberg AJ, Hilt JZ, Dziubla TD. 2019. Fluorescence based detection of polychlorinated biphenyls (PCBs) in water using hydrophobic interactions. Analyst 144(2):677-684. doi:10.1039/c8an00867a PMID:30511719 PMCID:PMC6331228
  • Frazar EM, Shah RA, Dziubla TD, Hilt JZ. 2019. Multifunctional temperature-responsive polymers as advanced biomaterials and beyond. J Appl Polym Sci doi:10.1002/app.48770
  • Gutierrez AM, Bhandari R, Weng J, Stromberg AJ, Dziubla TD, Hilt JZ. 2019. Novel magnetic core-shell nanoparticles for the removal of polychlorinated biphenyls from contaminated water sources. Mater Chem Phys 223:68-74. doi:10.1016/j.matchemphys.2018.10.045 PMID:31452560 PMCID:PMC6710019
  • Savage DT, Hilt JZ, Dziubla TD. 2019. In vitro methods for assessing nanoparticle toxicity. In: Nanotoxicity. Humana Press, New York, NY. pp.1-29.


  • Gupta P, Thompson B, Wahlang B, Jordan CT, Hilt JZ, Hennig B, Dziubla TD. 2018. The environmental pollutant, polychlorinated biphenyls, and cardiovascular disease: a potential target for antioxidant nanotherapeutics. Drug Deliv Transl Res 8(3):740-759. doi:10.1007/s13346-017-0429-9 PMID:28975503 PMCID:PMC5882597


  • Gupta P, Lacerda C, Patil VS, Biswal D, Wattamwar P, Hilt JZ, Dziubla TD. 2017. Degradation of poly(beta-amino ester) hydrogels in alcohols through transesterification: a method to conjugate drugs to hydrogel matrices. J Polym Sci A Polym Chem 55(12):2019–2026. PMID:29398778
  • Gutierrez AM, Dziubla TD, Hilt JZ. 2017. Recent advances on iron oxide magnetic nanoparticles as sorbents of organic pollutants in water and wastewater treatment. Rev Environ Health 32(1-2):111-117. doi:10.1515/reveh-2016-0063 PMID:28231068
  • Patil VS, Gutierrez AM, Sunkara M, Morris AJ, Hilt JZ, Kalika DS, Dziubla TD. 2017. Curcumin acrylation for biological and environmental applications. J Nat Prod 80:1964-1971. doi:10.1021/acs.jnatprod.6b00951 PMID:28661687
  • Tang S, Bhandari R, Delaney SP, Munson EJ, Dziubla TD, Hilt JZ. 2017. Synthesis and characterization of thermally responsive N-isopropylacrylamide hydrogels copolymerized with novel hydrophobic polyphenolic crosslinkers. Mater Today Commun 10:46-53. PMID:28989952 PMCID:PMC562875
  • Tang S, Floy M, Bhandari R, Dziubla TD, Hilt JZ. 2017. Development of novel N-isopropylacrylamide (NIPAAm) based hydrogels with varying content of chrysin multiacrylate. Gels 3(4):40. doi:10.3390/gels3040040 PMID:29805968 PMCID:PMC5967267
  • Tang S, Floy M, Bhandari R, Sunkara M, Morris AJ, Dziubla TD, Hilt JZ. 2017. Synthesis and characterization of thermoresponsive hydrogels based on N-isopropylacrylamide crosslinked with 4,4’-dihydroxybiphenyl diacrylate. ACS Omega 2(12):8723-8729. doi:10.1021/acsomega.7b01247 PMID:29302630 PMCID:PMC5748278


  • Dziubla TD, Hilt JZ, Bhandari R, Gupta P. 2016. Single step synthesis, characterization and applications of curcumin functionalized iron oxide magnetic nanoparticles. Mater Sci Eng C Mater Biol Appl 67:59-64. doi:10.1016/j.msec.2016.04.093 PMID:27287099


  • Petriello MC, Newsome B, Dziubla TD, Hilt JZ, Bhattacharyya D, Hennig B. 2014. Modulation of persistent organic pollutant toxicity through nutritional intervention: emerging opportunities in biomedicine and environmental remediation. Sci Total Environ 491-492:11-16. doi:10.1016/j.scitotenv.2014.01.109 PMID:24530186 PMCID:PMC4077968


  • Xiao L, Isner AB, Hilt JZ, Bhattacharyya D. 2013. Temperature responsive hydrogel with reactive nanoparticles. J Appl Polym Sci 128(3):1804-1814. doi:10.1002/app.38335


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