Superfund Research Program

Laurie G. Hudson

University of New Mexico
1 University of New Mexico
Albuquerque, New Mexico 87131-0001
Phone: 505-272-2482
Email: lhudson@salud.unm.edu

Projects

• University of New Mexico: Biomarkers and Mechanisms of Metal and Mixed Metal Exposures (2022-2027)
• University of New Mexico: Modulation of Uranium and Arsenic Immune Dysregulation by Zinc (2017-2022)

Publications

• Hoover JH, Bolt AM, Burchiel SW, Cerrato JM, Dashner-Titus EJ, Erdei E, Hayek EE, Hudson LG, Gonzalez-Estrella J, Luo L, MacKenzie D, Medina S, Schilz JR, Velasco CA, Zychowski KE, Lewis JL. A transdisciplinary approach for studying uranium mobility, exposure, and human health impacts on tribal lands in the southwest, United States. In: Practical Applications of Medical Geology. Springer,

2024

• Speer RM, Yu H, Zhou X, Nandi S, Alexandrov LB, Guo Y, Hudson LG, Liu K. 2024. Arsenic and UVR co-exposure results in unique gene expression profile identifying key co-carcinogenic mechanisms. Toxicol Appl Pharmacol 482:116773. doi:10.1016/j.taap.2023.116773 PMID:38036231

2023

• Dashner-Titus EJ, Schilz JR, Alvarez SA, Wong Cp, Simmons KA, Ho E, Hudson LG. 2023. Zinc supplementation alters tissue distribution of arsenic in Mus musculus. Toxicol Appl Pharmacol 478:116709. doi:10.1016/j.taap.2023.116709 PMID:37797845
• Speer RM, Zhou X, Volk L, Liu K, Hudson LG. 2023. Arsenic and cancer: evidence and mechanisms. Adv Pharmacol 96:151-202. doi:10.1016/bs.apha.2022.08.001 PMID:36858772 PMCID:10860672

2022

• Cooper KL, Volk L, Dominguez DR, Duran AD, Liu K, Hudson LG. 2022. Contribution of NADPH oxidase to the retention of UVR-induced DNA damage by arsenic. Toxicol Appl Pharmacol 434:115799. doi:10.1016/j.taap.2021.115799 PMID:34798142
• Du R, Li L, Hudson LG, Nozadi S, Lewis JL. 2022. An adjusted partial least squares regression framework to utilize additional exposure information in environmental mixture data analysis. Journal of Applied Statistics doi:10.1080/02664763.2022.2043254
• Schilz JR, Dashner-Titus EJ, Simmons KA, Erdei E, Bolt AM, MacKenzie D, Hudson LG. 2022. The immunotoxicity of natural and depleted uranium: From cells to people. Toxicol Appl Pharmacol 454:116252. doi:10.1016/j.taap.2022.116252 PMID:36152676
• Volk L, Cooper KL, Jiang T, Paffett ML, Hudson LG. 2022. Impacts of arsenic on Rad18 and translesion synthesis. Toxicol Appl Pharmacol 454:116230. doi:10.1016/j.taap.2022.116230 PMID:36087615

2021

• Schilz JR, Dashner-Titus EJ, Luo L, Simmons KA, MacKenzie D, Hudson LG. 2021. Co-exposure of sodium arsenite and uranyl acetate differentially alters gene expression in CD3/CD28 activated CD4+ T-cells. Toxicol Rep 8:1917-1929. doi:10.1016/j.toxrep.2021.11.019
• Shankar P, Dashner-Titus EJ, Truong L, Hayward K, Hudson LG, Tanguay RL. 2021. Developmental toxicity in zebrafish (Danio rerio) exposed to uranium: A comparison with lead, cadmium, and iron. Environ Pollut 269:116097. doi:10.1016/j.envpol.2020.116097 PMID:33246768 PMCID:PMC7785642
• Zhou X, Speer RM, Volk L, Hudson LG, Liu K. 2021. Arsenic co-carcinogenesis: Inhibition of DNA repair and interaction with zinc finger proteins. Semin Cancer Biol 76:86-98. doi:10.1016/j.semcancer.2021.05.009 PMID:33984503 PMCID:PMC8578584

2020

• Dashner-Titus EJ, Schilz JR, Simmons KA, Duncan TR, Alvarez SC, Hudson LG. 2020. Differential response of human T-lymphocytes to arsenic and uranium. Toxicol Lett 333:269-278. doi:10.1016/j.toxlet.2020.08.013 PMID:32866568 PMCID:PMC7590629

2019

• Luo L, Hudson LG, Lewis JL, Lee J. 2019. Two-step approach for assessing the health effects of environmental chemical mixtures: application to simulated datasets and real data from the Navajo Birth Cohort Study. Environ Health 18(46):doi:10.1186/s12940-019-0482-6 PMID:31072361 PMCID:PMC6507239

2018

• Dashner-Titus EJ, Hoover JH, Li L, Lee J, Du R, Liu K, Traber MG, Ho E, Lewis JL, Hudson LG. 2018. Metal exposure and oxidative stress markers in pregnant Navajo Birth Cohort Study participants. Free Radic Biol Med 124:484-492. doi:10.1016/j.freeradbiomed.2018.04.579 PMID:29723666 PMCID:PMC6381929

2014

• Burchiel SW, Lauer FT, Beswick EJ, Gandolfi A, Parvez F, Liu K, Hudson LG. 2014. Differential susceptibility of human peripheral blood T cells to suppression by environmental levels of sodium arsenite and monomethylarsonous acid. PLoS One 9:8. doi:10.1371/journal.pone.0109192 PMID:25271956 PMCID:PMC4182801
• Ezeh PC, Lauer FT, MacKenzie D, McClain S, Liu K, Hudson LG, Gandolfi A, Burchiel SW. 2014. Arsenite selectively inhibits mouse bone marrow lymphoid progenitor cell development in vivo and in vitro and suppresses humoral immunity in vivo. PLoS One 9(4):e93920. doi:10.1371/journal.pone.0093920 PMID:24714590 PMCID:PMC3979857
• Zhou X, Sun X, Mobarak C, Gandolfi A, Burchiel SW, Hudson LG, Liu K. 2014. Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins. Chem Res Toxicol 27(4):690-698. doi:10.1021/tx500022j PMID:24611629 PMCID:PMC3998772