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Your Environment. Your Health.

Person Details: Steven M. Albelda

Superfund Research Program

Steven M. Albelda

University of Pennsylvania
Perelman School of Medicine Pulmonary, Allergy & Critical Care Division
Stemmler Hall, Office Suite 227
3450 Hamilton Walk
Philadelphia, Pennsylvania 19104
Phone: 215-573-9933
Fax: (215) 746-0376
Email: albelda@pennmedicine.upenn.edu

Projects

Publications

2022

  • Pietrofesa RA, Chatterjee S, Kadariya Y, Testa JR, Albelda SM, Christofidou-Solomidou M. 2022. Synthetic secoisolariciresinol diglucoside (LGM2605) prevents asbestos-induced inflammation and genotoxic cell damage in human mesothelial cells. Int J Mol Sci 23(17):10085. doi:10.3390/ijms231710085 PMID:36077483 PMCID:PMC9456329

2019

  • Christofidou-Solomidou M, Pietrofesa RA, Park K, Albelda SM, Serve KM, Kiel DE, Pfau JC. 2019. Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice. Toxicol Appl Pharmacol 375:81-93. doi:10.1016/j.taap.2019.04.018 PMID:31022494 PMCID:PMC6582645

2018

  • Pietrofesa RA, Chatterjee S, Park K, Arguiri E, Albelda SM, Christofidou-Solomidou M. 2018. Synthetic lignan secoisolariciresinol diglucoside (LGM2605) reduces asbestos-induced inflammation and inflammasome activation in mice in an Nrf2-dependent and independent manner. Antioxidants (Basel) 7(3):38. doi:10.3390/antiox7030038 PMID:29498660 PMCID:PMC5874524

2017

  • Pietrofesa RA, Woodruff P, Hwang W, Patel P, Chatterjee S, Albelda SM, Christofidou-Solomidou M. 2017. The synthetic lignan secoisolariciresinol diglucoside prevents asbestos-induced NLRP3 inflammasome activation in murine macrophages. Oxid Med Cell Longev 2017:739523. doi:10.1155/2017/7395238 PMID:29075366 PMCID:PMC5615985

2016

  • Pietrofesa RA, Velalopoulou A, Albelda SM, Christofidou-Solomidou M. 2016. Asbestos induces oxidative stress and activation of Nrf2 signaling in murine macrophages: chemopreventive role of the synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605). Int J Mol Sci 17(3):322. doi:10.3390/ijms17030322 PMID:26938529 PMCID:PMC4813184
  • Pietrofesa RA, Velalopoulou A, Arguiri E, Menges CW, Testa JR, Hwang W, Albelda SM, Christofidou-Solomidou M. 2016. Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice. Carcinogenesis 37(2):177-187. doi:10.1093/carcin/bgv174 PMID:26678224 PMCID:PMC4745643

2015

  • Mesaros C, Worth AJ, Snyder NW, Christofidou-Solomidou M, Vachani A, Albelda SM, Blair IA. 2015. Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure. Bioanalysis 7(9):1157-1173. doi:10.4155/bio.15.53 PMID:26039812 PMCID:PMC4487641
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