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Person Details: Christopher Chang

Superfund Research Program

Christopher Chang

University of California-Berkeley
532A Latimer Hall
Berkeley, California 94720-1460
Phone: 510-642-4704





  • Bruemmer KJ, Crossley S, Chang C. 2020. Activity based sensing: A synthetic methods approach for selective molecular imaging and beyond. Angew Chem Int Ed Engl 30:doi:10.1002/anie.201909690 PMID:31605413 PMCID:PMC7665898
  • Elledge S, Tran HL, Christian A, Steri V, Hann BC, Toste FD, Chang C, Wells JA. 2020. Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site specific antibody bioconjugation. Proc Natl Acad Sci U S A 117:5733-5740. doi:10.1073/pnas.1920561117 PMID:32123103 PMCID:PMC7084160
  • Morstein J, Hofler D, Ueno K, Jurss J, Walvoord R, Bruemmer KJ, Rezgui SP, Brewer TF, Saitoe M, Michel BW, Chang C. 2020. Ligand-Directed Approach to Activity-Based Sensing: Developing Palladacycle Fluorescent Probes That Enable Endogenous Carbon Monoxide Detection. J Am Chem Soc 142:15917-15930. doi:10.1021/jacs.0c06405 PMID:32872768
  • Shen X, Wang R, Kim M, Hu Q, Hsu C, Yao J, Klages-Mundt N, Tian Y, Lynn E, Brewer TF, Zhang Y, Arun B, Gan B, Andreeff M, Takeda S, Chen J, Park J, Shi X, Chang C, Jung SY, Qin J, Li L. 2020. A surge of DNA damage links transcriptional reprogramming and hematopoietic deficit in Fanconi anemia. Mol Cell 80(6):1013-1024. doi:10.1016/j.molcel.2020.11.040 PMID:33338401
  • Toh JD, Crossley S, Bruemmer KJ, Ge EJ, He D, Iovan DA, Chang C. 2020. Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates. Proc Natl Acad Sci U S A 117:25284-25292. doi:10.1073/pnas.2007349117 PMID:32989163 PMCID:PMC7568336
  • Ueno K, Morstein J, Ofusa K, Naganos S, Suzuki-Sawano E, Minegishi S, Rezgui SP, Kitagishi H, Michel BW, Chang C, Horiuchi J, Saitoe M. 2020. Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release. J Neurosci Res 40:3533-3548. doi:10.1523/JNEUROSCI.2378-19.2020 PMID:32253360 PMCID:PMC7189754



  • Chang C, Chung CY, Timblin GA, Saijo K. 2018. Versatile histochemical approach to detection of hydrogen peroxide in cells and tissues based on puromycin staining. J Am Chem Soc 140(19):6109-6121. doi:10.1021/jacs.8b02279 PMID:29722974 PMCID:PMC6069982
  • Su TA, Shihadih DS, Cao W, Detomasi TC, Heffern MC, Jia S, Stahl A, Chang C. 2018. A modular lonophore platform for liver-directed copper supplementation in cells and animals. J Am Chem Soc 140(42):13764-13774. doi:10.1021/jacs.8b08014 PMID:30351140


  • Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang C, Vazquez A, Patel KJ. 2017. Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature 548:549-554. doi:10.1038/nature23481 PMID:28813411 PMCID:PMC5714256
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