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Your Environment. Your Health.

Person Details: Sanjay Srivastava

Superfund Research Program

Sanjay Srivastava

University of Louisville
Cardiovascular Innovation Institute
320 E. Muhammad Ali Blvd
Louisville, Kentucky 40202-1756
Phone: 502-852-5834
Email: sanjay@louisville.edu

Projects

Publications

2022

  • Lorkiewicz P, Keith RJ, Lynch J, Jin L, Theis W, Krivokhizhina T, Riggs D, Bhatnagar A, Srivastava S, Conklin DJ. 2022. Electronic cigarette solvents, JUUL e-liquids, and biomarkers of exposure: In vivo evidence for acrolein and glycidol in e-cig-derived aerosols. Chem Res Toxicol doi:10.1021/acs.chemrestox.1c00328 PMID:35044764
  • Riggs DW, Malovichko MV, Gao H, McGraw KE, Taylor BS, Krivokhizhina T, Rai SN, Keith RJ, Bhatnagar A, Srivastava S. 2022. Environmental exposure to volatile organic compounds is associated with endothelial injury. Toxicol Appl Pharmacol 437:115877. doi:10.1016/j.taap.2022.115877 PMID:35045333
  • Shuck B, Hart J, Walker KL, Rai J, Srivastava S, Srivastava S, Rai SN, Bhatnagar A, Keith RJ. 2022. Workplace culture and biomarkers of health risk. Int J Environ Res Public Health 19(19):11920. doi:10.3390/ijerph191911920 PMID:36231223 PMCID:PMC9565767
  • Wahlang B, Gripshover T, Gao H, Krivokhizhina T, Keith RJ, Sithu ID, Rai SN, Bhatnagar A, McClain CJ, Srivastava S, Cave MC. 2022. Associations between residential exposure to volatile organic compounds and liver injury markers. Toxicol Sci 185(1):doi:10.1093/toxsci/kfab119 PMID:34668566 PMCID:PMC8714366

2021

  • Jin L, Lorkiewicz P, Xie Z, Bhatnagar A, Srivastava S, Conklin DJ. 2021. Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications. Toxicol Appl Pharmacol 426:115647. doi:10.1016/j.taap.2021.115647 PMID:34271065 PMCID:PMC8343963
  • Jin L, Lynch J, Richardson A, Lorkiewicz P, Srivastava S, Theis W, Shirk G, Hand A, Bhatnagar A, Srivastava S, Conklin DJ. 2021. Electronic cigarette solvents, pulmonary irritation and endothelial dysfunction: role of acetaldehyde and formaldehyde. Am J Physiol Heart Circ Physiol doi:10.1152/ajpheart.00878.2020 PMID:33543686
  • Malovichko MV, Abplanalp WT, McFall SA, Taylor BS, Wickramasinghe NS, Sithu ID, Zelko I, Uchida S, Hill BG, Sutaria S, Nantz MH, Bhatnagar A, Conklin DJ, O'Toole TE, Srivastava S. 2021. Subclinical markers of cardiovascular toxicity of benzene inhalation in mice. Toxicol Appl Pharmacol 431(9):115742. doi:10.1016/j.taap.2021.115742 PMID:34624356 PMCID:PMC8647905
  • McGraw KE, Riggs DW, Rai SN, Navas-Acien A, Xie Z, Lorkiewicz P, Lynch J, Zafar N, Krishnasamy SS, Taylor KC, Conklin DJ, DeFilippis A, Srivastava S, Bhatnagar A. 2021. Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction. Environ Res 196:110903. doi:10.1016/j.envres.2021.110903 PMID:33636185 PMCID:PMC8119348
  • Pfeiffer JA, Hart J, Wood LA, Bhatnagar A, Keith RJ, Yeager R, Smith T, Tomlinson M, Gilkey D, Kerstiens S, Gao H, Srivastava S, Walker KL. 2021. The importance of urban planning: Views of greenness and open space is reversely associated with self-reported views and depressive symptoms. Popul Med 3:20. doi:10.18332/popmed/139173 PMID:34368779 PMCID:PMC8341459
  • Wood LA, Tomlinson M, Pfeiffer JA, Walker KL, Keith RJ, Smith T, Yeager R, Bhatnagar A, Kerstiens S, Gilkey D, Gao H, Srivastava S, Hart J. 2021. Time spent outdoors and sleep normality: A preliminary investigation. Popul Med 3:7. doi:10.18332/popmed/132119 PMID:34485920 PMCID:PMC8411876
  • Zelko I, Dassanayaka S, Malovichko MV, Howard CM, Garrett LF, Uchida S, Brittian KR, Conklin DJ, Jones SP, Srivastava S. 2021. Chronic benzene exposure aggravates pressure overload-induced cardiac dysfunction. Toxicol Sci 185(1):64-76. doi:10.1093/toxsci/kfab125 PMID:34718823 PMCID:PMC8714365
  • Zelko I, Taylor BS, Das TP, Watson WH, Sithu ID, Wahlang B, Malovichko MV, Cave MC, Srivastava S. 2021. Effect of vinyl chloride exposure on cardiometabolic toxicity. Environ Toxicol 37(2):245-255. doi:10.1002/tox.23394 PMID:34717031 PMCID:PMC8724461

2020

  • Donde H, Ghare S, Joshi-Barve S, Zhang J, Vadhanam MV, Gobejishvili L, Lorkiewicz P, Srivastava S, McClain CJ, Barve S. 2020. Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury. Cell Mol Gastroenterol Hepatol 9:569-585. doi:10.1016/j.jcmgh.2019.10.005 PMID:31654770 PMCID:PMC7078548
  • Yeager R, Riggs DW, DeJarnett N, Srivastava S, Lorkiewicz P, Xie Z, Krivokhizhina T, Keith RJ, Srivastava S, Browning MH, Zafar N, Krishnasamy SS, DeFilippis A, Turner JR, Rai SN, Bhatnagar A. 2020. Association between residential greenness and exposure to volatile organic compounds. Sci Total Environ 707:doi:10.1016/j.scitotenv.2019.135435 PMID:31865083

2019

  • Abplanalp WT, Wickramasinghe NS, Sithu S, Conklin DJ, Xie Z, Bhatnagar A, Srivastava S, O'Toole TE. 2019. Benzene exposure induces insulin resistance in mice. Toxicol Sci 167(2):426-437. doi:10.1093/toxsci/kfy252 PMID:30346588 PMCID:PMC6358255
  • Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu S, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H. 2019. Myeloid-specific deletion of epsins 1 and 2 reduces atherosclerosis by preventing LRP-1 downregulation. Circ Res 124:e6-e19. doi:10.1161/circresaha.118.313028 PMID:30595089 PMCID:PMC6375743
  • Conklin DJ, Schick SF, Blaha MJ, Carll AP, DeFilippis A, Ganz P, Hall MN, Hamburg NM, O'Toole TE, Reynolds LM, Srivastava S, Bhatnagar A. 2019. Cardiovascular injury induced by tobacco products: Assessment of risk factors and biomarkers of harm A Tobacco Center of Regulatory Science (TCORS) Compilation. Am J Physiol Heart Circ Physiol 316(4):H801-H827. doi:10.1152/ajpheart.00591.2018 PMID:30707616
  • Vatsalya V, Kong M, Gobejishvili L, Chen W, Srivastava S, Barve S, McClain CJ, Joshi-Barve S. 2019. Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients. Am J Physiol Gastrointest Liver Physiol 316(1):G115-G122. doi:10.1152/ajpgi.00209.2018 PMID:30234998

2018

  • Conklin DJ, Ogunwale M, Chen Y, Theis W, Nantz MH, Fu X, Chen L, Riggs DW, Lorkiewicz P, Bhatnagar A, Srivastava S. 2018. Electronic cigarette-generated aldehydes: the contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of exposure. Aerosol Science and Technology 52:1219-1232. doi:10.1080/02786826.2018.1500013
  • Lorkiewicz P, Riggs DW, Keith RJ, Conklin DJ, Xie Z, Sutaria S, Lynch BJ, Srivastava S, Bhatnagar A. 2018. Comparison of urinary biomarkers of exposure in humans using electronic cigarettes, combustible cigarettes, and smokeless tobacco. Nicotine Tob Res doi:10.1093/ntr/nty089 PMID:29868926
  • Xie Z, Lorkiewicz P, Riggs DW, Bhatnagar A, Srivastava S. 2018. Comprehensive, robust, and sensitive UPLC-MS/MS analysis of free biogenic monoamines and their metabolites in urine. J Chromatogr B Analyt Technol Biomed Life Sci 1099:83-91. doi:10.1016/j.jchromb.2018.09.012 PMID:30248561 PMCID:PMC6398444
  • Yeager R, Riggs DW, DeJarnett N, Tollerud DJ, Wilson J, Conklin DJ, O'Toole TE, McCracken J, Lorkiewicz P, Xie Z, Zafar N, Krishnasamy SS, Srivastava S, Finch J, Keith RJ, DeFilippis A, Rai SN, Liu G, Bhatnagar A. 2018. Association between residential greenness and cardiovascular disease risk. J Am Heart Assoc 7(24):e009117. doi:10.1161/JAHA.118.009117 PMID:30561265 PMCID:PMC6405613
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