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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Dr. Christopher K. Glass

Superfund Research Program

Dr. Christopher K. Glass

University of California-San Diego
9500 Gilman Drive
M/C: 0651
La Jolla, California 92093-0651
Phone: 858-534-6011
Fax: 858-822-2127
Email: cglass@ucsd.edu

Projects

Publications

2022

2021

  • Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas M, Ricciardelli E, Li RZ, Troutman T, Kisseleva T, Glass CK, Brenner DA. 2021. Heterogeneity of HSCs in a mouse model of NASH. Hepatology 74(2):667-685. doi:10.1002/hep.31743 PMID:33550587 PMCID:PMC8346581

2020

  • Sun X, Seidman J, Zhao P, Troutman T, Spann N, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida J, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. 2020. Neutralization of oxidized phospholipids ameliorates non-alcoholic steatohepatitis. Cell Metab 31(1):189-206. doi:10.1016/j.cmet.2019.10.014 PMID:31761566 PMCID:PMC7028360
  • Xu J, Ma H, Liu X, Rosenthal SB, Baglieri J, Mccubbin R, Sun M, Koyama Y, Geoffroy C, Saijo K, Shang L, Nishio T, Maricic I, Kriefeldt M, Kusumanchi P, Roberts a, Zheng B, Kumar V, Zengler K, Pizzo D, Hosseini M, Contet C, Glass CK, Liangpunsakul S, Tsukamoto H, Gao B, Karin M, Brenner DA, Koob G, Kisseleva T. 2020. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. JCI Insight doi:10.1172/jci.insight.131277 PMID:32051339 PMCID:PMC7098802

2018

  • Que X, Hung M, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Maatta A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Yla-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. 2018. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301. doi:10.1038/s41586-018-0198-8 PMID:29875409 PMCID:PMC6033669

2004

  • Cunard R, Eto Y, Muljadi JT, Glass CK, Kelly CJ, Ricote M. 2004. Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma. J Immunol 172(12):7530-7536. PMID:15187132
  • Valledor AF, Hsu L, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. 2004. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci U S A 101(51):17813-17818. PMID:15601766

2003

  • Welch JS, Ricote M, Akiyama TE, Gonzalez FJ, Glass CK. 2003. PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A 100(11):6712-6717. PMID:12740443

2002

  • Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee Y, Ricote M, Glass CK, Brewer HB, Gonzalez FJ. 2002. Conditional disruption of the PPARg gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol Cell Biol 22(8):2607-2619. PMID:11909955
  • Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK, Kelly CJ. 2002. WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo. J Immunol 169(12):6806-6812. PMID:12471112
  • Cunard R, Ricote M, DiCampli D, Archer DC, Kahn DA, Glass CK, Kelly CJ. 2002. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol 168(6):2795-2802. PMID:11884448
  • Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. 2002. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J Biol Chem 277(45):42821-42829. PMID:12215441

2001

  • Glass CK. 2001. Potential roles of the peroxisome proliferator-activated receptor-g in macrophage biology and atherosclerosis. Journal of Endocrinology 169:461-464. PMID:11375116
  • Glass CK, Witzum JL. 2001. Atherosclerosis, the road ahead. Cell 104:503-516. PMID:11239408
  • Murata T, Kurokawa R, Krones A, Tatsumi K, Ishii M, Taki T, Masuno M, Ohashi H, Yanagisawa M, Rosenfeld MG, Glass CK, Hayashi Y. 2001. Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi Syndrome. Hum Mol Genet 10(10):1071-1076. PMID:11331617
  • Rosenfeld MG, Glass CK. 2001. Coregulator codes of transcriptional regulation by nuclear receptors. J Biol Chem 276:36865-36868. PMID:11459854
  • Straus DS, Glass CK. 2001. Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev 21(3):185-210. PMID:11301410

2000

  • Ricote M, Welch JS, Glass CK. 2000. Regulation of macrophage gene expression bythe peroxisome proliferator-actived receptor-gamma. Horm Res 54:275-280. PMID:11595817
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