Superfund Research Program

Dr. Hyam L. Leffert

University of California-San Diego
Department of Pharmacology
9500 Gilman Drive
Mail Code 0636
La Jolla, California 92093-0636
Phone: 858-534-2354
Fax: 858-822-4184
Email: hleffert@ucsd.edu

Projects

• University of California-San Diego: Outreach Core (2000 - 2005)

Publications

2011

• Koch KS, Leffert HL. 2011. Ectopic expression of CD74 in Ikk beta-deleted mouse hepatocytes. Acta Histochemica 113:428-435. doi:10.1016/j.acthis.2010.03.004 PMID:20569972 PMCID:PMC2965206

2009

• Koch KS, Maeda S, Karin M, Leffert HL, He G. 2009. Targeted deletion of hepatocyte Ikkbeta confers growth advantages. Biochem Biophys Res Commun 380(2):349-354. doi:10.1016/j.bbrc.2009.01.085 PMID:19171122 PMCID:PMC2663043

2005

• Maeda S, Kamata H, Luo J, Leffert HL, Karin M. 2005. IKKB couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121(7):977-990. PMID:15989949
• Zhang M, Joseph B, Gupta S, Guest I, Xu M, Sell S, Son K, Koch KS, Leffert HL. 2005. Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats. Stem Cells 23(2):186-199. PMID:15671142

2004

• Son K, Zhang M, Rucobo E, Nwaigwe D, Montgomery F, Leffert HL. 2004. Derivation and study of human epithelial cell lines resistant to killing by chromium trioxide. J Toxicol Environ Health A 67(13):1027-1049. PMID:15205032

2003

• Koch KS, Leffert HL. 2003. Normal liver progenitor cells in culture. In: Stem Cells Handbook. Humana Press, Inc., Totowa, NJ.
• Maeda S, Chang L, Li Z, Luo J, Leffert HL, Karin M. 2003. IKK beta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNF alpha. Immunity 19(5):725-737. PMID:14614859
• Zhang M, Sell S, Leffert HL. 2003. Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from gamma-irradiated mouse STO cells. Stem Cells 21(4):449-458. PMID:12832698

2002

• Yin L, Sun M, Ilic Z, Leffert HL, Sell S. 2002. Derivation, characterization, and phenotypic variation of hepatic progenitor cell lines isolated from adult rats. Hepatology 35(2):315-324. PMID:11826404

2001

• Fabregat I, Koch KS, Aoki T, Atkinson AE, Dang H, Amosova O, Fresco JR, Schildkraut CL, Leffert HL. 2001. Functional pleiotropy of an intramolecular triplex-forming fragment from the 3'UTR of the rat Pigr gene. Physiol Genomics 5(2):53-65. PMID:11242589