Superfund Research Program
Mohammad I. Sabri
Oregon Health and Science University
Center for Research on Occupational and Environmental Toxicology
3181 S.W. Sam Jackson Park Road, L606
Portland, Oregon 97239-3098
Phone: 503-494-2509
Fax: 503-494-4278
Email: sabri@ohsu.edu
Projects
- Oregon Health and Science University: Biomarkers of Neurotoxicant Exposure and Neurodegeneration (2000-2006)
Research Briefs
Publications
2005
- Tshala-Katumbay DD, Palmer VS, Kayton RJ, Sabri MI, Spencer PS. 2005. A new murine model of giant proximal axonopathy. Acta Neuropathol 109(4):405-410. PMID:15759132
2004
- Palmer VS, Tshala-Katumbay DD, Hashemi SB, Sabri MI, Spencer PS. 2004. Tetralin and metabolites: protein reactivity, chromogenicity and neurotoxicity. In: Proceedings of the 43rd Annual Meeting of the Society of Toxicology (SOT), March 21-25, 2004. Baltimore, MD.
- Tshala-Katumbay DD, Palmer VS, Dixon DA, Deinzer ML, Sabri MI, Spencer PS. 2004. Structural requirements for hydrocarbon axonopathy. J Neurochem 90:19-19Suppl.1.
2003
- Dixon DA, Zhan C, Spencer PS, Sabri MI, Kim M. 2003. Theoretical determination of chromophores to determine the chromogenic effects of neurotoxicants. In: Proceedings of the 226th ACS (American Chemical Society) National Meeting - Fall 2003. New York, NY.
- Kim M, Lasarev MR, Hashemi SB, Nagalla SR, Sabri MI, Spencer PS. 2003. Gene modulation patterns associated with aromatic y-diketones neurotoxicity. Environ Health Perspect 67:740.
- Sabri MI, Hashemi SB, Spencer PS. 2003. Neurotoxicity and reactivity of 1,2-diacetylbenzene (1,2-DAB) with motor and cytoskeletal proteins in rat spinal cord and sciatic nerves. Toxicol Lett 144(Suppl.1):s130.
- Tshala-Katumbay DD, Palmer VS, Kayton RJ, Sabri MI, Spencer PS. 2003. Demonstration of murine neurotoxic responses to 1,2-diacetylbenzene preparatory to toxicogenomic characterization. Environ Health Perspect 67:357.
2002
- Kim M, Spencer PS, Sabri MI. 2002. Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy. Toxicol Appl Pharmacol 183(1):55-65. PMID:12217642
- Kim M, Taylor MJ, Sabri MI, Spencer PS. 2002. In vivo reactivity of the axonal toxin 1,2-diacetylbenzene with neurofilament and microtubule proteins. Environ Health Perspect 66:15.
- Sabri MI, Hashemi SB, Kim M, Spencer PS. 2002. Aromatic hydrocarbon 1,2-diacetylbenzene cross-links neurofilaments and other proteins. J Neurochem 81:103.
- Sabri MI, Spencer PS. 2002. How does acrylamide perturb axon transport and induce nerve fiber degeneration? Commentary on forum position paper. Neurotoxicology 23(2):259-63;discussion265-70. PMID:12224766
- Spencer PS, Kim M, Sabri MI. 2002. Aromatic as well as aliphatic hydrocarbon solvent axonopathy. Int J Hyg Environ Health 205(1-2):131-136. PMID:12018006
- Zhan C, Dixon DA, Spencer PS, Kim M, Sabri MI. 2002. Theoretical determination of chromophores in the chromogenic effects of aromatic neurotoxicants. J Am Chem Soc 124(11):2744-2752. PMID:11890826
2001
- Kim M, Sabri MI, Miller VH, Kayton RJ, Dixon DA, Spencer PS. 2001. 1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy. Toxicol Appl Pharmacol 177(2):121-131. PMID:11740911
2000
- Sabri MI, Kim M, Spencer PS. 2000. The aromatic hydrocarbon 1,2-diacetylbenzene induces pathological changes in the rodent nervous system. Toxicol Lett 116(1):72.