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Person Details: Brenda Eskenazi

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Superfund Research Program

Brenda Eskenazi

University of California-Berkeley
Environmental Health Sciences
140 Warren Hall
Berkeley, California 94720-7360
Phone: 510-642-3496
Fax: 510-642-9083


Research Briefs



  • Welch BM, Keil AP, Buckley JP, Calafat AM, Christenbury KE, Engel SM, O'Brien KM, Rosen EM, James-Todd T, Zota AR, Ferguson KK, Alshawabkeh AN, Cordero JF, Meeker JD, Barrett ES, Bush NR, Nguyen RH, Sathyanarayana S, Swan SH, Cantonwine DE, Aalborg J, Dabelea D, Starling AP, Hauser R, Messerlian C, Zhang Y, Bradman A, Eskenazi B, Charley PH, Holland NT, Bloom MS, Newman RB, Wenzel AG, Braun JM, Lanphear BP, Yolton K, Factor-Litvak P, Herbstman JB, Rauh VA, Drobnis EZ, Sparks AE, Redmon JB, Wang C, Binder AM, Michels KB, Baird DD, Jukic AM, Weinberg CR, Wilcox AJ, Rich DQ, Weinberger B, Padmanabhan V, Watkins DJ, Hertz-Picciotto I, Schmidt RJ. 2022. Associations between prenatal urinary biomarkers of phthalate exposure and preterm birth: A pooled study at 16 US cohorts. JAMA Pediatr doi:10.1001/jamapediatrics.2022.2252 PMID:35816333 PMCID:PMC9274448


  • Schantz SL, Eskenazi B, Buckley JP, Braun JM, Sprowles JN, Bennett DH, Cordero JF, Frazier JA, Lewis JL, Hertz-Picciotto I, Lyall K, Nozadi S, Sagiv SK, Stroustrup A, Watkins DJ. 2020. A framework for assessing the impact of chemical exposures on neurodevelopment in ECHO: opportunities and challenges. Environ Res 188:109709. doi:10.1016/j.envres.2020.109709 PMID:32526495


  • Luderer U, Eskenazi B, Hauser R, Korach KS, McHale CM, Moran-Messen FM, Rieswijk L, Solomon G, Udagawa O, Zhang L, Zlatnik M, Zeise L, Smith MT. 2019. Proposed key characteristics of female reproductive toxicants as an approach for organizing and evaluating mechanistic data in hazard assessment. Environ Health Perspect 127:75001. doi:10.1289/ehp4971 PMID:31322437 PMCID:PMC6791466



  • Ji Z, Weldon RH, Marchetti F, Chen H, Li G, Xing C, Kurtovich E, Young SS, Schmid TE, Waidyanatha S, Rappaport SM, Zhang L, Eskenazi B. 2012. Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene. Environ Mol Mutagen 53(3):218-26. doi:10.1002/em.21683 PMID:22351378
  • Marchetti F, Eskenazi B, Weldon RH, Li G, Zhang L, Rappaport SM, Schmid TE, Xing C, Kurtovich E, Wyrobek AJ. 2012. Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese men. Environ Health Perspect 120(2):229-234. doi:10.1289/ehp.1103921 PMID:22086566 PMCID:PMC3279447
  • Schmid TE, Eskenazi B, Marchetti F, Young SS, Weldon RH, Baumgartner A, Anderson D, Wyrobek AJ. 2012. Micronutrients intake is associated with improved sperm DNA quality in older men. Fertil Steril 98:1130-1137. doi:10.1016/j.fertnstert.2012.07.1126 PMID:22935557


  • Xing C, Marchetti F, Li G, Weldon RH, Kurtovich E, Young SS, Schmid TE, Zhang L, Rappaport SM, Waidyanatha S, Wyrobek AJ, Eskenazi B. 2010. Benzene exposure near the US permissible limit is associated with sperm aneuploidy. Environ Health Perspect 118:833-839. doi:10.1289/ehp.0901531 PMID:20418200 PMCID:PMC2898861



  • Young SS, Eskenazi B, Marchetti F, Block G, Wyrobek AJ. 2008. The association of folate, zinc and antioxidant intake with sperm aneuploidy in healthy non-smoking men. Hum Reprod 23(5):1014-1022. doi:10.1093/humrep/den036 PMID:18353905


  • von Ehrenstein OS, Poddar S, Yuan Y, Guha-Mazumder DN, Eskenazi B, Basu A, Hira Smith MM, Ghosh N, Lahiri S, Haque R, Ghosh A, Kalman DA, Das S, Smith AH. 2007. Children's intellectual function in relation to arsenic exposure. Epidemiology 18(1):44-51. PMID:17149142


  • Sloter E, Schmid TE, Marchetti F, Eskenazi B, Nath J, Eskenazi AJ. 2006. Quantitative effects of male age on sperm motion. Hum Reprod 21(11):2868-75. PMID:16793993


  • Eskenazi B, Kidd SA, Marks AR, Sloter E, Block G, Wyrobek AJ. 2005. Antioxidant intake is associated with semen quality in healthy men. Hum Reprod 20(4):1006-1012. PMID:15665024


  • Duramad P, McMahon CW, Hubbard AE, Eskenazi B, Holland NT. 2004. Flow cytometric detection of intracellular Th1/Th2 cytokines using whole blood: Validation of immunologic biomarker for use in epidemiologic studies. Cancer Epidemiol Biomarkers Prev 13(9):1452-1458. PMID:15342445
  • Landrigan PJ, Kimmel CA, Correa A, Eskenazi B. 2004. Children's health and the environment: public health issues and challenges for risk assessment. Environ Health Perspect 112(2):257-265. PMID:14754581
  • Sloter E, Nath J, Eskenazi B, Wyrobek AJ. 2004. Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodents. Fertil Steril 81(4):925-943. PMID:15066442


  • Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Young SS, Moore DH. 2003. The association of age and semen quality in healthy men. Hum Reprod 18(2):447-454. PMID:12571189
  • Glaser RL, Broman KW, Schulman RL, Eskenazi B, Wyrobek AJ, Jabs EW. 2003. The paternal-age effect in Apert syndrome is due, in part, to the increased frequency of mutations in sperm. Am J Hum Genet 73(4):939-947. PMID:12900791
  • Holland NT, Smith MT, Eskenazi B, Bastaki B. 2003. Challenges of biological sample collection and processing for large epidemiological projects. Mutat Res Rev Mutat Res 7702:1-18.
  • Holland NT, Smith MT, Eskenazi B, Bastaki M. 2003. Biological sample collection and processing for molecular epidemiological studies. Mutat Res Rev Mutat Res 543(3):217-234. PMID:12787814


  • Eskenazi B, Wyrobek AJ, Kidd SA, Lowe X, Moore DH, Weisiger K, Aylstock M. 2002. Sperm aneuploidy in fathers of children with paternally and maternally inherited Klinefelter syndrome. Hum Reprod 17(3):576-583. PMID:11870106
  • Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Moore LE, Young SS, Moore DH, Nath J. 2002. Semen quality and chromosomal integrity of sperm decreases with age among healthy men. Environ Mol Mutagen 39(Supp33):59.
  • Tiemann-Boege I, Navidi W, Grewal R, Cohn D, Eskenazi B, Wyrobek AJ, Arnheim N. 2002. The observed human sperm mutation frequency cannot explain the achondroplasia paternal age effect. Proc Natl Acad Sci U S A 99(23):14952-14957. PMID:12397172


  • Kidd SA, Eskenazi B, Wyrobek AJ. 2001. Effects of male age on semen quality and fertility: a review of the literature. Fertil Steril 75(2):237-248. PMID:11172821
  • Lowe X, Eskenazi B, Nelson DO, Kidd SA, Alme A, Wyrobek AJ. 2001. Frequency of XY sperm increases with age in fathers of boys with Klinefelter syndrome. Am J Hum Genet 69(5):1046-1054. PMID:11582569
  • Sloter E, Eskenazi B, Kidd SA, Moore DH, Hill F, Nath J, Wyrobek AJ. 2001. Effects of age on structural chromosomal abnormalities in sperm from healthy men. Environ Mol Mutagen 37(32):70.


  • Eskenazi B, Mocarelli P, Warner M, Samuels S, Vercellini P, Olive D, Needham LL, Patterson DG, Brambilla P. 2000. Seveso Women's Health Study: a study of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive health. Chemosphere 40(9-11):1247-1253. PMID:10739069


  • Eskenazi B, Bradman A, Castorina R. 1999. Exposures of children to organophosphate pesticides and their potential adverse health effects. Environ Health Perspect 107(Suppl.3):409-419. PMID:10346990
  • Eskenazi B, Stapleton AL, Kharrazi M, Chee W. 1999. Associations between maternal decaffeinated and caffeinated coffee consumption and fetal growth and gestational duration. Epidemiology 10(3):242-249. PMID:10230832
  • Eskenazi B, Warner M. 1999. Epidemiologic issues in the study of endometriosis. In: Proceedings of the Vth World Congress on Endometriosis: Understanding Endometriosis.
  • Kharrazi M, Epstein D, Hopkins B, Kreutzer R, Doebbert G, Hiatt R, Swan S, Eskenazi B, Pirkle JL, Bernert JT. 1999. Evaluation of four maternal smoking questions. Public Health Rep 114(1):60-70. PMID:9925173 PMCID:PMC1308345
  • Matkin CC, Britton JA, Samuels S, Eskenazi B. 1999. Smoking and blood pressure patterns in normotensive pregnant women. Paediatr Perinat Epidemiol 13(1):22-34. PMID:9987783


  • Eskenazi B, Chuu Y, Kidd SA, Lowe X, Aylstock M, Weisiger K, Moore DH, Wyrobek AJ. 1998. Elevated frequencies of aneuploid sperm (x-y and 21-21) in fathers of boys with klinefelter syndrome (47, x-x-y), when the extra x-chromosome was of paternal origin. Am J Epidemiol 147(11):S11.
  • Lowe X, Eskenazi B, Kidd SA, Alme A, Weisiger K, Aylstock M, Nelson DE, Wyrobek AJ. 1998. Sperm disomy 21 is associated with sex chromosomal aneuploidies but does not preferentially segregate with the Y chromosome: a study of 38 healthy fertile men. Am J Hum Genet 63(4):A143.
  • Wyrobek AJ, Eskenazi B, Chuu Y, Kidd SA, Lowe X, Weisiger K, Aylstock M, Sloter E, Moore DH, Katz D. 1998. Genetic Biomarkers in Human Sperm: Applications in Reproductive Epidemiology. In: Proceedings of the Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.


  • Chuu Y, Lowe X, Kidd SA, Weisiger K, Eskenazi B, Wyrobek AJ. 1997. Elevated Frequencies Of Hyperhaploid Sperm Were Detected In A Man With A History Of Multiple Aneuploid Pregnancies. In: Proceedings of Environmental Mutagen Society Meeting, 1997. Minneapolis, MN.
  • Robbins WA, Meistrich ML, Moore DH, Hagemeister FB, Weier H, Cassel MJ, Wilson G, Eskenazi B, Wyrobek AJ. 1997. Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm. Nat Genet 16:74-78. PMID:9140398
  • Wyrobek AJ, Eskenazi B, Chuu Y, Kidd SA, Lowe X, Weisiger K, Aylstock M, Sloter E, Moore DH, Katz D. 1997. Genetic biomarkers in human sperm: Applications in reproductive epidemiology. In: Proceedings of the Superfund Basic Research Program: A decade of improving health through multi-disciplinary research, Chapel Hill, NC, February 23-26, 1997. Chapel Hill, NC.


  • Eskenazi B, Gold EB, Lasley BL, Samuels S, Hammond SK, Wight S, Rasor MO, Hines CJ, Schenker MB. 1995. Prospective monitoring of early fetal loss and clinical spontaneous abortion among female semiconductor workers. Am J Ind Med 28(6):833-846. PMID:8588567
  • Eskenazi B, Gold EB, Samuels S, Wight S, Lasley BL, Hammond SK, Rasor MO, Schenker MB. 1995. Prospective assessment of fecundability of female semiconductor workers. Am J Ind Med 28(6):817-831. PMID:8588566
  • Gold EB, Eskenazi B, Hammond SK, Lasley BL, Samuels S, Rasor MO, Hines CJ, Overstreet JW, Schenker MB. 1995. Prospectively assessed menstrual cycle characteristics in female wafer-fabrication and nonfabrication semiconductor employees. Am J Ind Med 28(6):799-815. PMID:8588565
  • Gold EB, Eskenazi B, Lasley BL, Samuels S, Rasor MO, Overstreet JW, Schenker MB. 1995. Epidemiologic methods for prospective assessment of menstrual cycle and reproductive characteristics in female semiconductor workers. Am J Ind Med 28(6):783-797. PMID:8588564
  • Lasley BL, Lohstroh PN, Kuo A, Gold EB, Eskenazi B, Samuels S, Stewart DR, Overstreet JW. 1995. Laboratory methods for evaluating early pregnancy loss in an industry-based population. Am J Ind Med 28(6):771-781. PMID:8588563
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