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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: William M. Baird

Superfund Research Program

William M. Baird

Oregon State University
Department of Environmental and Molecular Toxicology
1158 Ag and Life Sciences Building
Corvallis, Oregon 97331-7301
Phone: 541-737-1886
Fax: 541-737-0497
Email: william.baird@orst.edu

Projects

Publications

2018

  • Hummel JM, Madeen E, Siddens LK, Uesugi S, McQuistan TJ, Anderson KA, Turteltaub KW, Ognibene T, Bench G, Krueger SK, Harris S, Smith JN, Tilton SC, Baird WM, Williams DE. 2018. Pharmacokinetics of [(14)C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem Toxicol 115:136-147. doi:10.1016/j.fct.2018.03.003 PMID:29518434 PMCID:PMC5935529

2017

  • Madeen E, Lohr CV, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer LM, Waters KM, Williams DE, You H. 2017. Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 56(1):163-171. doi:10.1002/mc.22480 PMID:26990437

2016

  • Madeen E, Ognibene T, Corley RA, Henderson MC, Baird WM, Bench G, Turteltaub KW, Williams DE, McQuistan TJ. 2016. Human microdosing with carcinogenic polycyclic aromatic hydrocarbons: in vivo pharmacokinetics of dibenzo[def,p]chrysene and metabolites by UPLC accelerator mass spectrometry. Chem Res Toxicol 29(10):1641-1650. doi:10.1021/acs.chemrestox.6b00169 PMID:27494294 PMCID:PMC5380438

2015

  • Larkin A, Williams DE, Kile ML, Baird WM. 2015. Developing a smartphone software package for predicting atmospheric pollutant concentrations at mobile locations. Comput J 58(6):1431-1442. doi:10.1093/comjnl/bxu067 PMID:26146409 PMCID:PMC4489712
  • Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Lohr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE, Baird WM. 2015. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol 287(2):149-160. doi:10.1016/j.taap.2015.05.019 PMID:26049101 PMCID:PMC4689210
  • Tilton SC, Siddens LK, Krueger SK, Larkin A, Lohr CV, Williams DE, Baird WM, Waters KM. 2015. Mechanism-based classification of PAH mixtures to predict carcinogenic potential. Toxicol Sci 146(1):135-145. doi:10.1093/toxsci/kfv080 PMID:25908611 PMCID:PMC4476464

2013

  • Crowell SR, Sharma AK, Amin S, Soelberg JJ, Sadler NC, Wright AT, Baird WM, Williams DE, Corley RA. 2013. Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice. Toxicol Sci 135(1):48-62. doi:10.1093/toxsci/kft124 PMID:23744095 PMCID:PMC3748759
  • Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM. 2013. Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin. Toxicol Appl Pharmacol 267(2):192-199. doi:10.1016/j.taap.2012.12.011 PMID:23274566 PMCID:PMC3626406

2012

  • Shorey LE, Castro DJ, Baird WM, Siddens LK, Lohr CV, Matzke MM, Waters KM, Corley RA, Williams DE. 2012. Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): Timing of maternal exposures determines target tissue response in offspring. Cancer Lett 317(1):49-55. doi:10.1016/j.canlet.2011.11.010 PMID:22085489 PMCID:PMC3269513
  • Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Lohr CV, Arlt VM, Phillips DH, Williams DE, Baird WM. 2012. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol 264(3):377-386. doi:10.1016/j.taap.2012.08.014 PMID:22935520 PMCID:PMC3483092

2011

  • Larkin A, Siddens LK, Krueger SK, Baird WM, Williams DE. 2011. Developing a fuzzy neural network model for predicting the interactive effects of complex PAH mixtures on the CYP1B1 transcriptional regulatory network. In: Superfund Research Program Annual Meeting Oct. 24-25. Lexington, KY.
  • Madeen EP, Larkin A, Siddens LK, Krueger SK, Lohr CV, Anderson KA, Simonich SL, Williams DE, Baird WM. 2011. Transplacental exposure to individual environmental carcinogens or mixtures, and dietary intervention as a chemoprevention strategy. In: Superfund Research Program Annual Meeting Oct. 24-25. Lexington, KY.
  • Vondracek J, Marvanova S, Ciganek M, Neca J, Pencikova K, Mahadevan B, Topinka J, Baird WM, Kozubik A, Machala M, Andrysik Z. 2011. Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: The role of polycyclic aromatic hydrocarbons. Mutat Res 714:53-62. doi:10.1016/j.mrfmmm.2011.06.011 PMID:21762708 (Completed with ARRA Funds)

2010

  • Larkin A, Siddens LK, Krueger SK, Madeen EP, Williams DE, Baird WM. 2010. Gene expression profiling in the skin of FVB/N mice treated with environmental PAH mixtures. Environ Mol Mutagen 51(7):735. doi:10.1002/em.20625
  • Siddens LK, Castro DJ, Larkin A, Simonich SL, Arlt VM, Phillips DH, Löhr C, Krueger SK, Williams DE, Baird WM, Swanson HI. 2010. Skin and transplacental carcinogenesis in mice following application of individual polycyclic aromatic hydrocarbons (PAHs) and environmental mixtures. In: Biological Radical Intermediates VIII Proceedings. Barcelona, Spain.
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