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Your Environment. Your Health.

Person Details: Cristian Coarfa

Superfund Research Program

Cristian Coarfa

Baylor College of Medicine
BCM-Cullen Building
Room: BCMC-450A
Mail Stop: BCM130
Houston, Texas 77030
Phone: 713-798-7938
Email: coarfa@bcm.edu

Projects

Publications

2022

  • Bobak C, Abhimanyu A, Natarajan H, Gandhi T, Grimm SL, Nishiguchi T, Koster K, Longlax SC, Dlamini Q, Kahari J, Mtetwa G, Cirillo JD, O'Malley J, Hill J, Coarfa C, DiNardo AR. 2022. Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis. Aging-US 14(5):2174-2193. doi:10.18632/aging.203936 PMID:35256539 PMCID:PMC8954968
  • Chacon-Alberty L, Kanchi R, Ye S, Hochman-Mendez C, Daoud D, Coarfa C, Li M, Grimm SL, Baz M, Rosas I, Loor G. 2022. Plasma protein biomarkers for primary graft dysfunction after lung transplantation: a single-center cohort analysis. Sci Rep 12(1):16137. doi:10.1038/s41598-022-20085-y PMID:36167867 PMCID:PMC9515157
  • DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S, Abhimanyu ., Cirillo JD, Kaufmann SH, Netea MG, Crevel Rv, Mandalakas AM, Coarfa C. 2022. Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. European Respiratory Journal 60(3):2102263. doi:10.1183/13993003.02263-2021 PMID:35169026 PMCID:PMC9474892
  • Napoli M, Wu SJ, Gore BL, Abbas H, Lee K, Checker R, Dhar S, Rajapakshe K, Tan AC, Lee MG, Coarfa C, Flores ER. 2022. Np63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer. Nat Commun 13:doi:10.1038/s41467-022-28202-1 PMID:35105868 PMCID:PMC8807845
  • Roy ER, Chiu G, Li S, Propson NE, Kanchi R, Wang B, Coarfa C, Zheng H, Cao W. 2022. Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques. Immunity 55:879-894. doi:10.1016/j.immuni.2022.03.018 PMID:35443157 PMCID:PMC9109419
  • Saie AE, Fu C, Grimm SL, Robertson M, Hoffman K, Putluri V, Ambati CS, Putluri N, Shivanna B, Coarfa C, Pammi M. 2022. Metabolome and microbiome multi-omics integration from a murine lung inflammation model of bronchopulmonary dysplasia. Pediatric Research 10:doi:10.1038/s41390-022-02002-1 PMID:35338351
  • Thaiparambil J, Dong J, Grimm SL, Perera D, Ambati CS, Putluri V, Robertson M, Patel TD, Mistretta B, Gunaratne PH, Kim MP, Yustein JT, Putluri N, Coarfa C, El-Zein R. 2022. Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer. Cancer Med doi:10.1002/cam4.4933 PMID:35676822
  • Thompson D, Fu C, Gandhi T, Fowler JC, Frueh BC, Weinstein BL, Petrosino J, Hadden JK, Carlson M, Coarfa C, Madan A. 2022. Differential co-expression networks of the gut microbiota are associated with depression and anxiety treatment resistance among psychiatric inpatients. Prog Neuropsychopharmacol Biol Psychiatry 120:110638. doi:10.1016/j.pnpbp.2022.110638 PMID:36122838

2021

  • Anvari S, Watkin L, Rajapakshe K, Hassan O, Schuster K, Coarfa C, Davis CM. 2021. Memory and naive gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy. Clin Immunol 230:108820. doi:10.1016/j.clim.2021.108820 PMID:34365017 PMCID:PMC8607808
  • Bomidi C, Robertson M, Coarfa C, Estes MK, Blutt SE. 2021. Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection. Proc Natl Acad Sci U S A 118(45):doi:10.1073/pnas.2112814118 PMID:34732579 PMCID:PMC8609316
  • Coarfa C, Grimm SL, Rajapakshe K, Perera D, Lu H, Wang X, Christensen KR, Mo Q, Edwards D, Huang S. 2021. Reverse-phase protein array: technology, application, data processing, and integration. J Biomol Tech doi:10.7171/jbt.2021-3202-001 PMID:33584151 PMCID:PMC7861052 (ahead of print)
  • Grimm SL, Dong X, Zhang Y, Carisey AF, Arnold AP, Moorthy B, Coarfa C, Lingappan K. 2021. Effect of sex chromosomes versus hormones in neonatal lung injury. JCI Insight 6(13):e146863. doi:10.1172/jci.insight.146863 PMID:34061778 PMCID:PMC8410054
  • Kaochar S, Rusin A, Foley C, Rajapakshe K, Robertson M, Skapura D, Mason C, Ruiz CB, Tyryshkin AM, Deng J, Shin JN, Fiskus W, Dong J, Huang S, Navone NM, Davis CM, Ehli EA, Coarfa C, Mitsiades N. 2021. Inhibition of GATA2 in prostate cancer by a clinically available small molecule. Endocr Relat Cancer 29(1):15-31. doi:10.1530/ERC-21-0085 PMID:34636746 PMCID:PMC8634153
  • Mao H, Li L, Fan Q, Angelini A, Saha PK, Coarfa C, Rajapakshe K, Perera D, Cheng J, Wu H, Ballantyne CM, Sun Z, Pi X, Xie L. 2021. Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nat Commun 12:doi:10.1038/s41467-021-25673-6 PMID:34489478 PMCID:PMC8421392

2020

  • Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker C, Moorthy B, Lingappan K. 2020. Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox Biol 37:101718. doi:10.1016/j.redox.2020.101718 PMID:32961439 PMCID:PMC7509469
  • Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim J, Dustin D, Lo H, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans W, Ando S, Fuqua SA. 2020. Hormonal modulation of ESR1 mutant metastasis. Oncogene 40(5):doi:10.1038/s41388-020-01563-x PMID:33323970 (ahead of print)
  • Preidis GA, Soni KG, Suh J, Halder T, Kim K, Choi J, Li F, Devaraj S, Connor ME, Coarfa C, Jung SY, Moore DD. 2020. Coagulopathy in Malnourished Mice is Sexually Dimorphic and Regulated by Nutrient-sensing Nuclear Receptors. Hepatol Commun 4:1835-1850. doi:10.1002/hep4.1622 PMID:33305154 PMCID:PMC7706303

2019

  • Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou GD, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B. 2019. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun 516(2):344-349. doi:10.1016/j.bbrc.2019.06.049 PMID:31208719 PMCID:PMC6637943
  • Xia J, Chiu L, Nehring R, Bravo Nunez M, Mei Q, Perez M, Zhai Y, Fitzgerald D, Pribis J, Wang Y, Hu C, Powell R, LaBonte S, Jalali A, Matadamas Guzman M, Lentzsch A, Szafran AT, Joshi M, Richters M, Gibson J, Frisch R, Hastings P, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM. 2019. Bacteria-to-human protein networks reveal origins of endogenous DNA damage. Cell 176(1-2):127-143. doi:10.1016/j.cell.2018.12.008 PMID:30633903 PMCID:PMC6344048
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