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Person Details: Detlef Knappe

Superfund Research Program

Detlef Knappe

North Carolina State University
Mann Hall 319E, Box 7908
Raleigh, North Carolina 27695
Phone: 919-515-8791




  • Cuffney M, Wilkie AA, Kotlarz N, Knappe D, Lea CS, Collier D, DeWitt JC, Hoppin JA. 2023. Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: The GenX exposure study. Environ Res 237:117020. doi:10.1016/j.envres.2023.117020 PMID:37673120
  • Ruyle BJ, Pickard HM, Schultes L, Fredriksson F, Heffernan AL, Knappe D, Lord HL, Meng P, Mills MA, Ndunga K, Roesch P, Rundberget JT, Tettenhorst DR, Van Buren J, Vogel C, Westerman DC, Yeung LW, Sunderland EM. 2023. Interlaboratory comparison of extractable organofluorine measurements in groundwater and eel (Anguilla rostrata): recommendations for methods standardization. Environ Sci Technol 57(48):20159-20168. doi:10.1021/acs.est.3c04560 PMID:37934924 PMCID:PMC10702518
  • Wallis DJ, Kotlarz N, Knappe D, Collier D, Lea CS, Reif DM, McCord JP, Strynar M, DeWitt JC, Hoppin JA. 2023. Estimation of the half-lives of recently detected per- and polyfluorinated alkyl ethers in an exposed community. Environ Sci Technol 57(41):15348-15355. doi:10.1021/acs.est.2c08241 PMID:37801709
  • Zhang C, Tang T, Knappe D. 2023. Oxidation of per- and polyfluoroalkyl ether acids and other per- and polyfluoroalkyl substances by sulfate and hydroxyl radicals: kinetic insights from experiments and models. Environ Sci Technol doi:10.1021/acs.est.3c00947 PMID:37223990


  • Evich MG, Davis MJ, McCord JP, Acrey B, Awkerman JA, Knappe D, Lindstrom AB, Speth TF, Tebes-Stevens C, Strynar M, Wang Z, Weber EJ, Henderson WM, Washington JW. 2022. Per- and polyfluoroalkyl substances in the environment. Science 375:doi:10.1126/science.abg9065 PMID:35113710 PMCID:PMC8902460
  • Rosen EM, Kotlarz N, Knappe D, Lea CS, Collier D, Richardson DB, Hoppin JA. 2022. Drinking water-associated PFAS and fluroethers and lipid outcomes in the GenX exposure study. Environ Health Perspect 130(9):97002. doi:10.1289/EHP11033 PMID:36069575 PMCID:PMC9450637
  • Wallis DJ, Barton KE, Knappe D, Kotlarz N, McDonough CA, Higgins CP, Hoppin JA, Adgate JL. 2022. Source apportionment of serum PFASs in two highly exposed communities. Sci Total Environ 855:158842. doi:10.1016/j.scitotenv.2022.158842 PMID:36122706
  • Zhang C, McElroy AC, Liberatore H, Alexander NL, Knappe D. 2022. Stability of per- and polyfluoroalkyl substances in solvents relevant to environmental and toxicological analysis. Environ Sci Technol doi:10.1021/acs.est.1c03979 PMID:34734715 PMCID:PMC9065217


  • Dodds J, Alexander NL, Kirkwood KI, Foster MR, Hopkins ZR, Knappe D, Baker ES. 2021. From Pesticides to Per- and Polyfluoroalkyl Substances: An Evaluation of Recent Targeted and Untargeted Mass Spectrometry Methods for Xenobiotics. Anal Chem 93:641-656. doi:10.1021/acs.analchem.0c04359 PMID:33136371


  • Dodds J, Hopkins ZR, Knappe D, Baker ES. 2020. Rapid characterization of per- and polyfluoroalkyl substances (PFAS) by ion mobility spectrometry-mass spectrometry (IMS-MS). Anal Chem 92:4427-4435. doi:10.1021/acs.analchem.9b05364 PMID:32011866 PMCID:PMC7173758
  • Kwiatkowski C, Andrews DQ, Birnbaum LS, Bruton TA, DeWitt JC, Knappe D, Maffini MV, Miller M, Pelch KE, Reade A, Soehl A, Trier X, Venier M, Wagner CC, Wang Z, Blum A. 2020. Scientific basis for managing PFAS as a chemical class. Environ Sci Technol Lett 7:532-543. doi:10.1021/acs.estlett.0c00255
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