Superfund Research Program

Carla A. Ng

University of Pittsburgh
3700 O'Hara St.
203 Benedum Hall
Pittsburgh, Pennsylvania 15261
Phone: 412-383-4075
Email: carla.ng@pitt.edu

Projects

• SUNY at Buffalo: Model-aided Design and Integration of Functionalized Hybrid Nanomaterials for Enhanced Bioremediation of Per-and Polyfluoroalkyl Substances (PFASs) (2021-2025)
• University of Pittsburgh: Studying AFFF Fate and Exposure to Pursue Outcomes that Restore Trust: SAFE PORT (2022-2023)

Publications

2024

• DeWitt JC, Gluge J, Cousins IT, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Trier X, Vierke L, Wang Z, Adu-Kumi S, Balan SA, Buser A, Fletcher T, Haug L, Heggelund A, Huang J, Kaserzon S, Leonel J, Sheriff I, Shi Y, Valsecchi S, Scheringer M. 2024. Zurich II statement on per- and polyfluoroalkyl substances (PFASs): scientific and regulatory needs. Environ Sci Technol Lett 11(8):786-797. doi:10.1021/acs.estlett.4c00147 PMID:39156923 PMCID:11325642

2023

• Antle J, Larock M, Falls Z, Ng CA, Atilla-Gokcumen G, Aga DS, Simpson S. 2023. Building chemical intuition about physicochemical properties of C8-per-/polyfluoroalkyl carboxylic acids through computational means. ACS ES&T Eng 4(1):196-208. doi:10.1021/acsestengg.3c00267
• Marciesky M, Aga DS, Bradley I, Aich N, Ng CA. 2023. Mechanisms and opportunities for rational in silico design of enzymes to degrade per- and polyfluoroalkyl substances (PFAS). J Chem Inf Model 63(23):7299-7319. doi:10.1021/acs.jcim.3c01303 PMID:37981739 PMCID:PMC10716909

2022

• Abrahamsson DP, Siddharth A, Robinson JF, Soshilov AA, Elmore S, Cogliano VJ, Ng CA, Khan EM, Ashton R, Chiu WA, Fung J, Zeise L, Woodruff TJ. 2022. Modeling the transplacental transfer of small molecules using machine learning: a case study on perand polyfluorinated substances (PFAS). J Expo Sci Environ Epidemiol 32(6):doi:10.1038/s41370-022-00481-2 PMID:36207486 PMCID:PMC9742309
• Gluge J, London R, Cousins IT, DeWitt JC, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Trier X, Wang Z, Scheringer M. 2022. Information requirements under the essential-use concept: PFAS case studies. Environ Sci Technol doi:10.1021/acs.est.1c03732 PMID:34608797 PMCID:PMC8980108

2021

• Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Wang Z. 2021. Finding essentiality feasible: Common questions and misinterpretations concerning the 'essential-use' concept. Environ Sci Process Impacts 23(8):doi:10.1039/d1em00180a PMID:34190275 (ahead of print)
• De Silva AO, Armitage JM, Bruton TA, Dassuncao C, Heiger-Bernays WJ, Hu XC, Karrman A, Kelly BC, Ng CA, Robuck AR, Sun M, Webster TF, Sunderland EM. 2021. PFAS exposure pathways for humans and wildlife: A synthesis of current knowledge and key gaps in understanding. Environ Toxicol Chem 40(3):631-657. doi:10.1002/etc.4935 PMID:33201517 PMCID:PMC7906948
• Ng CA, Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Patton S, Scheringer M, Trier X, Wang Z. 2021. Addressing urgent questions for PFAS in the 21st century. Environ Sci Technol 55(19):12755-12765. doi:10.1021/acs.est.1c03386 PMID:34519210 PMCID:PMC8590733

2020

• Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Scheringer M, Vierke L, Wang Z. 2020. Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to protect human and environmental health. Environ Sci Process Impacts 22:1444-1460. doi:10.1039/D0EM00147C PMID:32495786
• Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Ng CA, Scheringer M, Wang Z. 2020. The high persistence of PFAS is sufficient for their management as a chemical class. Environ Sci Process Impacts doi:10.1039/d0em00355g PMID:33230514
• Gluge J, Scheringer M, Cousins IT, Goldenman G, Herzke D, Lohmann R, DeWitt JC, Ng CA, Trier X, Wang Z. 2020. An overview of the uses of per- and polyfluoroalkyl substances (PFAS). Environ Sci Process Impacts 22:2345-2373. doi:10.1039/d0em00291g PMID:33125022 PMCID:PMC7784712
• Lohmann R, Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lindstrom AB, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Wang Z. 2020. Are fluoropolymers really of low concern for human and environmental health and separate from other PFAS?. Environ Sci Technol 54(20):12820-12828. doi:10.1021/acs.est.0c03244 PMID:33043667 PMCID:PMC7700770

2019

• Cousins IT, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Vierke L, Wang Z, DeWitt JC. 2019. The concept of essential use for determining when uses of PFASs can be phased out. Environ Sci Process Impacts 21:1803-1815. doi:10.1039/c9em00163h PMID:31204421 PMCID:PMC6992415