Superfund Research Program

Jia Chen

Mount Sinai School of Medicine
Department of Community and Preventive Medicine
1 Gustave L. Levy Place, Box 1043
New York, New York 10029
Phone: 212-241-7519
Fax: 212-360-6969
Email: jia.chen@mssm.edu

Projects

• Mount Sinai School of Medicine: Genetic Analysis (2001 - 2006)

Publications

2020

• Hussey MR, Burt AA, Deyssenroth MA, Jackson BP, Hao K, Peng S, Chen J, Marsit CJ, Everson TM. 2020. Placental lncRNA expression associated with placental cadmium concentrations and birth weight. Environ Epigenet 6:doi:10.1093/eep/dvaa003
• Tian F, Everson TM, Lester B, Punshon T, Jackson BP, Hao K, Lesseur C, Chen J, Karagas MR, Marsit CJ. 2020. Selenium-associated DNA methylation modifications in placenta and neurobehavioral development of newborns: An epigenome-wide study of two U.S. birth cohorts. Environ Int 137:doi:10.1016/j.envint.2020.105508 PMID:32007686 PMCID:PMC7722519

2018

• Barouki R, Melen E, Herceg Z, Beckers J, Chen J, Karagas MR, Puga A, Xia Y, Chadwick LH, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, Nohara K. 2018. Epigenetics as a mechanism linking developmental exposures to long-term toxicity. Environ Int 114:77-86. doi:10.1016/j.envint.2018.02.014 PMID:29499450 PMCID:PMC5899930
• Deyssenroth MA, Gennings C, Liu SH, Peng S, Hao K, Lambertini L, Jackson BP, Karagas MR, Marsit CJ, Chen J. 2018. Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network. Environ Int 120:373-381. doi:10.1016/j.envint.2018.08.010 PMID:30125854
• Everson TM, Punshon T, Jackson BP, Hao K, Lambertini L, Chen J, Karagas MR, Marsit CJ. 2018. Cadmium-associated differential methylation throughout the placental genome: epigenome-wide association study of two U.S. birth cohorts. Environ Health Perspect 126(1):017010. doi:10.1289/EHP2192 PMID:29373860 PMCID:PMC6014712

2017

• Everson TM, Kappil M, Hao K, Jackson BP, Punshon T, Karagas MR, Chen J, Marsit CJ. 2017. Maternal exposure to selenium and cadmium, fetal growth, and placental expression of steroidogenic and apoptotic genes. Environ Res 158:233-244. doi:10.1016/j.envres.2017.06.016 PMID:28662449 PMCID:PMC5554457

2005

• Wetmur JG, Kumar M, Zhang L, Palomeque C, Wallenstein S, Chen J. 2005. Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes. Nucleic Acids Res 33(8):2615-2619. PMID:15886392

2003

• Chen J, Hunter DJ, Stampfer MJ, Kyte C, Chan W, Wetmur JG, Selhub J, Ma J. 2003. Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer. Cancer Epidemiol Biomarkers Prev 12(10):958-962. PMID:14578129
• Chen J, Ma J, Stampfer MJ, Palomeque C, Selhub J, Hunter DJ. 2003. Linkage disequilibrium between the 677C>T and 1298 A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenet Genomics 12(4):339-342. PMID:12042673
• Shideler SE, Gee NA, Chen J, Laughlin LS, Rapp PR, Morrison JH, Roberts JA, Moran-Messen FM, Lasley BL. 2003. Contribution of ovarian steroid production to urinary estrone conjugate concentrations in Macaca mulatta. Am J Primatol 61(3):111-121. doi:10.1002/ajp.10114 PMID:14610729

2002

• Chen J, Gerner S, Higuchi R, Berkowitz GS, Godbold JH, Wetmur JG. 2002. Kinetic PCR on pooled DNA: a high efficiency alternative in genetic epidemiologic studies. Cancer Epidemiol Biomarkers Prev 11:131-136.
• Chen J, Ma J, Stampfer MJ, Hines LM, Selhub J, Hunter DJ. 2002. Alcohol dehydrogenase 3 genotype is not predictive for risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 10:1303-1304. PMID:11751450
• Li H, Chen J, Overstreet JW, Nakajima ST, Lasley BL. 2002. Urinary follicle-stimulating hormone peak as a biomarker for estimating the day of ovulation. Fertil Steril 77(5):961-966. PMID:12009351
• Wetmur JG, Kumar M, Berkowitz GS, Chen J. 2002. Increased influence of genetic variation on paraoxonase gene expression in neonates. Environ Mol Mutagen 93(Suppl33):67.

2001

• Chen J, Higuchi R, Gerner S, Berkowitz GS, Wetmur JG. 2001. Kinetic PCR on pooled DNA: a high-throughput, high-efficiency alternative in genetic epidemiologic studies. Proc Am Assoc Cancer Res 42:283.
• Chen J, Stampfer MJ, Ma J, Selhub J, Malinow MR, Hennekens CH, Hunter DJ. 2001. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis 154:667-672. PMID:11257268

1997

• Rogers CE, Tomita AV, Trowbridge PR, Gone J, Chen J, Zeeb PJ, Hemond HF, Thilly WG, Olmez I, Durant JL. 1997. Hair analysis does not support hypothesized arsenic and chromium exposure from drinking water in Woburn, Massachusetts. Environ Health Perspect 105(10):1090-1097. PMID:9349834

1996

• Chen J, Thilly WG. 1996. Mutational spectra vary with exposure conditions: benzo(a)pyrene in human cells. Mutat Res 357(1-2):209-217. PMID:8876696

1995

• Durant JL, Chen J, Hemond HF, Thilly WG. 1995. Elevated incidence of childhood leukemia in Woburn, Massachusetts: NIEHS Superfund Basic Research Program Search for Causes. Environ Health Perspect 103(Suppl.6):93-98. PMID:8549500