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Your Environment. Your Health.

Person Details: Bhagavatula Moorthy

Superfund Research Program

Bhagavatula Moorthy

Baylor College of Medicine
Texas Children's Hospital - Feigin Center
1102 Bates Ave
Suite C.530.04
Houston, Texas 77030
Phone: 832-824-3266
Email: bmoorthy@bcm.edu

Projects

Publications

2020

2019

  • Hassanin AA, Tavera-Garcia MA, Moorthy B, Zhou GD, Ramos KS. 2019. Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and early reprogramming of oncogenic regulatory networks. Am J Physiol Lung Cell Mol Physiol 317:doi:10.1152/ajplung.00304.2019 (accepted for publication)
  • Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou GD, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B. 2019. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun 516(2):344-349. doi:10.1016/j.bbrc.2019.06.049 PMID:31208719 PMCID:PMC6637943

2015

2011

1998

  • Randerath K, Sriram P, Moorthy B, Aston JP, Baan R, Van den Berg PT, Booth ED, Watson WP. 1998. Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH-DNA adducts. Chem Biol Interact 110(1-2):85-102. PMID:9566727

1997

  • Moorthy B, Sriram P, Randerath E, Randerath K. 1997. Effects of cytochrome P450 inducers on tamoxifen genotoxicity in female mice in vivo. Biochem Pharmacol 53:663-669. PMID:9113085

1996

  • Moorthy B, Randerath K. 1996. Pentachlorophenol enhances 9-hydroxybenzo(a)pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol. Arch Toxicol 70(11):696-703. PMID:8896715

1995

  • Moorthy B, Liehr JG, Randerath E, Randerath K. 1995. Evidence from [32P]-postlabeling and the use of pentachlorophenol for a novel metabolic activation pathway of diethyl stilbestrol and its dimethylether in mouse liver: likely " alpha-hydroxylation of ethyl group(s) followed by sulfate conjugation. Carcinogenesis 16(11):2643-2648.
  • Moorthy B, Sriram P, Randerath K. 1995. Effects of a single dose of the cytochrome P450 inducer, $-naphthoflavone, on hepatic and renal covalent DNA modifications (I-compounds). Toxicology 104:165-177. PMID:8560495
  • Vulimiri SV, Gupta MS, Smith CV, Moorthy B, Randerath K. 1995. Rapid decreases in indigenous covalent DNA modifications (I-compounds) in male Fischer 344 ra liver DNA by diquat treatment. Chem Biol Interact 95:1-16. PMID:7697743
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