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Your Environment. Your Health.

Person Details: David C. Christiani

Superfund Research Program

David C. Christiani

Harvard School of Public Health
Building 1, 14th Floor
665 Huntington Ave
Boston, Massachusetts 02115
Phone: 617-432-3323
Fax: 617-432-3441
Email: dchris@hsph.harvard.edu

Projects

Research Briefs

Hazardous Waste Sites

Bangladesh

  • Harvard School of Public Health: Genetic Epidemiology of Neurodevelopmental Metal Toxicity

Mexico City

  • Harvard School of Public Health: Genetic Epidemiology of Neurodevelopmental Metal Toxicity

Tar Creek (Ottawa County)

  • Harvard School of Public Health: Genetic Epidemiology of Neurodevelopmental Metal Toxicity

Publications

2019

  • Lin PD, Bromage S, Mostofa G, Rahman ML, Allen JG, Oken E, Kile ML, Christiani DC. 2019. Mediating role of arsenic in the relationship between diet and pregnancy outcomes: prospective birth cohort in Bangladesh. Environ Health 18:10. doi:10.1186/s12940-019-0450-1 PMID:30728020

2018

  • Bozack AK, Cardenas A, Quamruzzaman Q, Rahman M, Mostofa G, Christiani DC, Kile ML. 2018. DNA methylation in cord blood as mediator of the association between prenatal arsenic exposure and gestational age. Epigenetics 13(9):923-940. doi:10.1080/15592294.2018.1516453 PMID:30175652
  • Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 39(4):614-622. doi:10.1093/carcin/bgy031 PMID:29562322 PMCID:PMC5888955
  • Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Re: Application of the key characteristics of carcinogens in cancer hazard evaluation : response to Goodman, Lynch and Rhomberg. Carcinogenesis 39(8):1091-1093. doi:10.1093/carcin/bgy082 PMID:29982359 PMCID:PMC6067125
  • Lee JJ, Valeri L, Kapur K, Hasan O, Quamruzzaman Q, Wright RO, Bellinger DC, Christiani DC, Mazumdar M. 2018. Growth parameters at birth mediate the relationship between prenatal manganese exposure and cognitive test scores among a cohort of 2-to 3-year-old Bangladeshi children. Int J Epidemiol 47(4):1169-1179. doi:10.1093/ije/dyy069 PMID:29733356
  • Sun R, Wang Z, Henn BC, Su L, Lu Q, Lin X, Wright RO, Bellinger DC, Kile ML, Mazumdar M, Tellez-Rojo MM, Schnaas L, Christiani DC. 2018. Identification of novel loci associated with infant cognitive ability. Mol Psychiatry PMID:30120420
  • Woo MK, Young ES, Mostofa G, Afroz S, Hasan OS, Quamruzzaman Q, Bellinger DC, Christiani DC, Mazumdar M. 2018. Lead in air in Bangladesh: Exposure in a rural community with elevated blood lead concentrations among young children. Int J Environ Res Public Health 15(9):1947. doi:10.3390/ijerph15091947 PMID:30200642

2017

  • Henn BC, Bellinger DC, Hopkins MR, Coull BA, Ettinger AS, Jim R, Hatley EL, Christiani DC, Wright RO. 2017. Maternal and cord blood manganese concentrations and early childhood neurodevelopment among residents near a mining-impacted superfund site. Environ Health Perspect 125:9. doi:10.1289/ehp925 PMID:28665786
  • Lin PD, Bromage S, Mostofa G, Allen JG, Oken E, Kile ML, Christiani DC. 2017. Associations between diet and toenail arsenic concentration among pregnant women in Bangladesh: a prospective study. Nutrients 9(4):420. doi:10.3390/nu9040420 PMID:28441747 PMCID:PMC5409759
  • Rahman ML, Valeri L, Kile ML, Mazumdar M, Mostofa G, Qamruzzaman Q, Rahman M, Baccarelli A, Liang L, Christiani DC. 2017. Investigating causal relation between prenatal arsenic exposure and birthweight: are smaller infants more susceptible?. Environ Int 108:32-40. doi:10.1016/j.envint.2017.07.026 PMID:28787626 PMCID:PMC5623127
  • Sun R, Carroll RJ, Christiani DC, Lin X. 2017. Testing for gene-environment interaction under exposure misspecification. Biometrics doi:10.1111/biom.12813 PMID:29120492
  • Valeri L, Mazumdar M, Bobb JF, Henn BC, Rodrigues EG, Sharif OI, Kile ML, Quamruzzaman Q, Afroz S, Golam M, Amarasiriwardena C, Bellinger DC, Christiani DC, Coull BA, Wright RO. 2017. Effect of prenatal exposure to metal mixtures on neurodevelopmental outcomes at 20-40 months of age: Evidence from Rural Bangladesh. Environ Health Perspect 125:11. doi:10.1289/ehp614 PMID:28669934
  • Wagner PJ, Park H, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q. 2017. In vitro effects of lead on gene expression in neural stem cells and associations between up-regulated genes and cognitive scores in children. Environ Health Perspect 125(4):721-729. doi:10.1289/ehp265 PMID:27562236
  • Wang Z, Henn BC, Wang C, Wei Y, Li S, Sun R, Chen H, Wagner PJ, Lu Q, Lin X, Wright RO, Bellinger DC, Kile ML, Mazumdar M, Tellez-Rojo M, Schnaas L, Christiani DC. 2017. Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment. Environ Health 16:81. doi:10.1186/s12940-017-0288-3 PMID:28754176 PMCID:PMC5534076

2016

  • Claus Henn B, Ettinger AS, Hopkins MR, Jim R, Amarasiriwardena CJ, Christiani DC, Coull BA, Bellinger DC, Wright RO. 2016. Prenatal arsenic exposure and birth outcomes among a population residing near a mining-related Superfund site. Environ Health Perspect 124(8):1308-1315. doi:10.1289/ehp.1510070 PMID:26859631 PMCID:PMC4977047
  • Gleason K, Valeri L, Shankar AH, Hasan O, Quamruzzaman Q, Rodrigues EG, Christiani DC, Wright RO, Bellinger DC, Mazumdar M. 2016. Stunting is associated with blood lead concentration among Bangladeshi children aged 2-3 years. Environ Health 15(1):103. doi:10.1186/s12940-016-0190-4 PMID:27809911 PMCID:PMC5096334
  • Kile ML, Cardenas A, Rodrigues EG, Mazumdar M, Dobson CB, Golam M, Quamruzzaman Q, Rahman M, Christiani DC. 2016. Estimating effects of arsenic exposure during pregnancy on perinatal outcomes in a Bangladeshi cohort. Epidemiology 27(2):173-181. doi:10.1097/EDE.0000000000000416 PMID:26583609 PMCID:PMC4733817
  • Kile ML, Faraj JM, Ronnenberg AG, Quamruzzaman Q, Rahman M, Mostofa G, Afroz S, Christiani DC. 2016. A cross sectional study of anemia and iron deficiency as risk factors for arsenic-induced skin lesions in Bangladeshi women. BMC Public Health 16:158. doi:10.1186/s12889-016-2824-4 PMID:26880234 PMCID:PMC4754934
  • Rodrigues EG, Bellinger DC, Valeri L, Hasan OS, Quamruzzaman Q, Golam M, Kile ML, Christiani DC, Wright RO, Mazumdar M. 2016. Neurodevelopmental outcomes among 2- to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water. Environ Health 15:44. doi:10.1186/s12940-016-0127-y PMID:26968381 PMCID:PMC4788832

2015

  • Bobb JF, Valeri L, Henn BC, Wright RO, Mazumdar M, Godleski J, Coull BA, Christiani DC. 2015. Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics 16(3):493-508. doi:10.1093/biostatistics/kxu058 PMID:25532525
  • Mazumdar M, Christiani DC, Biswas SK, Hasan OS, Kapur K. 2015. Elevated sweat chloride levels due to arsenic toxicity. N Engl J Med 372(6):582-584. doi:10.1056/NEJMc1413312 PMID:25651269 PMCID:PMC4368195
  • Mazumdar M, Hasan OS, Hamid R, Valeri L, Paul L, Selhub J, Rodrigues EG, Silva F, Mia S, Mostofa G, Quamruzzaman Q, Rahman M, Christiani DC. 2015. Arsenic is associated with reduced effect of folic acid in myelomeningocele prevention: a case control study in Bangladesh. Environ Health 14:34. doi:10.1186/s12940-015-0020-0 PMID:25885259 PMCID:PMC4404044
  • Mazumdar M, Valeri L, Rodrigues EG, Hasan OS, Hamid R, Paul L, Selhub J, Silva F, Mostofa G, Quamruzzaman Q, Rahman M, Christiani DC. 2015. Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele. Birth Defects Res A Clin Mol Teratol 103(9):754-762. doi:10.1002/bdra.23399 PMID:26250961 PMCID:PMC4565773
  • Pearce N, Blair AE, Vineis P, Ahrens W, Andersen A, Anto JM, Armstrong BK, Baccarelli A, Beland FA, Berrington A, Bertazzi PA, Birnbaum LS, Brownson RC, Bucher JR, Cantor KP, Cardis E, Cherrie JW, Christiani DC, Cocco P, Coggon D, Comba P, Demers PA, Dement JM, Douwes J, Eisen EA, Engel LS, Fenske RA, Fleming LE, Fletcher T, Fontham E, Forastiere F, Frentzel-Beyme R, Fritschi L, Gerin M, Goldberg M, Grandjean P, Grimsrud TK, Gustavsson P, Haines A, Hartge P, Hansen J, Hauptmann M, Heederik D, Hemminki K, Hemon D, Hertz-Picciotto I, Hoppin JA, Huff J, Jarvholm B, Kang D, Karagas MR, Kjaerheim K, Kjuus H, Kogevinas M, Kriebel D, Kristensen P, Kromhout H, Laden F, Lebailly P, LeMasters G, Lubin JH, Lynch CF, Lynge E, Mannetje A, McMichael AJ, McLaughlin J, Marrett L, Martuzzi M, Merchant JA, Merler E, Merletti F, Miller A, Mirer F, Monson RR, Nordby K, Olshan A, Parent M, Perera F, Perry MJ, Pesatori AC, Pirastu R, Porta M, Pukkala E, Rice C, Richardson DB, Ritter L, Ritz B, Ronckers CM, Rushton L, Rusiecki JA, Rusyn I, Samet JM, Sandler DP, de Sanjose S, Schernhammer E, Costantini A, Seixas N, Shy C, Siemiatycki J, Silverman DT, Simonato L, Smith AH, Smith MT, Spinelli JJ, Spitz MR, Stallones L, Stayner LT, Steenland K, Stenzel M, Stewart BW, Stewart P, Symanski E, Terracini B, Tolbert PE, Vainio H, Vena J, Vermeulen R, Victora CG, Ward EM, Weinberg CR, Weisenburger DD, Wesseling C, Weiderpass E, Zahm SH. 2015. IARC monographs: 40 years of evaluating carcinogenic hazards to humans. Environ Health Perspect 123(6):507-514. doi:10.1289/ehp.1409149 PMID:25712798 PMCID:PMC4455595
  • Seow W, Pan W, Kile ML, Tong L, Baccarelli A, Quamruzzaman Q, Rahman M, Mostofa G, Rakibuz-Zaman M, Ahsan H, Lin X, Christiani DC, Kibriya MG. 2015. A distinct and replicable variant of the squamous cell carcinoma gene inositol polyphosphate-5-phosphatase modifies the susceptibility of arsenic-associated skin lesions in Bangladesh. Cancer 121(13):2222-2229. doi:10.1002/cncr.29291 PMID:25759212 PMCID:PMC4565788

2014

  • Fan T, Fang SC, Cavallari JM, Barnett IJ, Wang Z, Su L, Byun H, Lin X, Baccarelli A, Christiani DC. 2014. Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study. BMC Public Health 14:1279. doi:10.1186/1471-2458-14-1279 PMID:25512264 PMCID:PMC4302115
  • Gleason K, Shine JP, Shobnam N, Rokoff LB, Suchanda HS, Hasan OS, Mostofa G, Amarasiriwardena CJ, Quamruzzaman Q, Rahman M, Kile ML, Bellinger DC, Christiani DC, Wright RO, Mazumdar M. 2014. Contaminated turmeric is a potential source of lead exposure for children in rural Bangladesh. J Environ Public Health 2014:730636. doi:10.1155/2014/730636 PMID:25214856 PMCID:PMC4158309
  • Grashow R, Zhang J, Fang SC, Weisskopf MG, Christiani DC, Kile ML, Cavallari JM. 2014. Inverse association between toenail arsenic and body mass index in a population of welders. Environ Res 131:131-133. doi:10.1016/j.envres.2014.03.010 PMID:24721130 PMCID:PMC4035809
  • Kile ML, Houseman EA, Baccarelli A, Quamruzzaman Q, Rahman M, Mostofa G, Cardenas A, Wright RO, Christiani DC. 2014. Effect of prenatal arsenic exposure on DNA methylation and leukocyte subpopulations in cord blood. Epigenetics 9(5):774-782. doi:10.4161/epi.28153 PMID:24525453 PMCID:PMC4063836
  • Kile ML, Rodrigues EG, Mazumdar M, Dobson CB, Diao N, Golam M, Quamruzzaman Q, Rahman M, Christiani DC. 2014. A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh. Environ Health 13(1):29. doi:10.1186/1476-069X-13-29 PMID:24735908 PMCID:PMC4021291
  • Seow W, Kile ML, Baccarelli A, Pan W, Byun H, Mostofa G, Quamruzzaman Q, Rahman M, Lin X, Christiani DC. 2014. Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: a case-control follow-up study. Environ Mol Mutagen 55(6):449-456. doi:10.1002/em.21860 PMID:24677489 PMCID:PMC4082746

2013

2012

  • Kile ML, Baccarelli A, Hoffman E, Tarantini L, Quamruzzaman Q, Rahman M, Mahiuddin G, Mostofa G, Hsueh Y, Wright RO, Christiani DC. 2012. Prenatal arsenic exposure and DNA methylation in maternal and umbilical cord blood leukocytes. Environ Health Perspect 120:1061-6. doi:10.1289/ehp.1104173 PMID:22466225 PMCID:PMC3404653
  • Lee S, Emond MJ, Bamshad MJ, Barnes KC, Rieder MJ, Nickerson DA, Christiani DC, Wurfel MM, Lin X. 2012. Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. Am J Hum Genet 91(2):224-237. doi:10.1016/j.ajhg.2012.06.007 PMID:22863193 PMCID:PMC3415556
  • Liu C, Maity A, Wright RO, Christiani DC, Lin X. 2012. Design and analysis issues in gene and environment studies. Environ Health 11:93. doi:10.1186/1476-069X-11-93 PMID:23253229 PMCID:PMC3551668
  • Oh RS, Pan W, Yalcin A, Zhang H, Guilarte TR, Hotamisligil GS, Christiani DC, Lu Q. 2012. Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress. J Biol Chem 287(8):6025-6034. doi:10.1074/jbc.M111.311217 PMID:22215663 PMCID:PMC3285369
  • Rodrigues EG, Kile ML, Hoffman E, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh Y, Christiani DC. 2012. GSTO and AS3MT genetic polymorphisms and differences in urinary arsenic concentrations among residents in Bangladesh. Biomarkers 17(3):240-247. doi:10.3109/1354750X.2012.658863 PMID:22339537 PMCID:PMC3340466
  • Seow W, Pan W, Kile ML, Baccarelli A, Quamruzzaman Q, Rahman M, Mahiuddin G, Mostofa G, Lin X, Christiani DC. 2012. Arsenic reduction in drinking water and improvement in skin lesions: A follow-up study in Bangladesh. Environ Health Perspect 121:1733-1738. doi:10.1289/ehp.1205381 PMID:23060367 PMCID:PMC3548283

2011

  • Claus Henn B, Kim J, Wessling-Resnick M, Tellez-Rojo MM, Jayawardene I, Ettinger AS, Hernandez-Avila M, Schwartz J, Christiani DC, Hu H, Wright RO. 2011. Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health 10(1):97. doi:10.1186/1476-069X-10-97 PMID:22074419 PMCID:PMC3248860
  • Kile ML, Hoffman E, Rodrigues EG, Breton CV, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh Y, Christiani DC. 2011. A pathway-based analysis of urinary arsenic metabolites and skin lesions. Am J Epidemiol 173(7):778-786. doi:10.1093/aje/kwq427 PMID:21378128 PMCID:PMC3105278
  • Lin X, Cai T, Wu MC, Zhou Q, Liu G, Christiani DC, Lin X. 2011. Kernel machine SNP-set analysis for censored survival outcomes in genome-wide association studies. Genet Epidemiol 35:620-631. doi:10.1002/gepi.20610 PMID:21818772 PMCID:PMC3373190

2010

2007

  • Breton CV, Kile ML, Catalano PJ, Hoffman E, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC. 2007. GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study. Environ Health 6:39. doi:10.1186/1476-069X-6-39 PMID:18053222 PMCID:PMC2222228
  • Kile ML, Houseman EA, Breton CV, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC. 2007. Association between total ingested arsenic and toenail arsenic concentrations. J Environ Sci Health A Tox Hazard Subst Environ Eng 42(12):1827-34. PMID:17952783
  • Kile ML, Houseman EA, Breton CV, Smith TJ, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC. 2007. Dietary arsenic exposure in bangladesh. Environ Health Perspect 115(6):889-893. doi:10.1289/ehp.9462 PMID:17589596 PMCID:PMC1892146
  • McCarty KM, Chen Y, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh Y, Su L, Smith TJ, Ryan L, Christiani DC. 2007. Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions. Environ Health Perspect 115(3):341-5. PMID:17431481
  • McCarty KM, Ryan LM, Houseman EA, Williams PL, Miller DP, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith TJ, Gonzalez E, Su L, Christiani DC. 2007. A case-control study of GST polymorphisms and arsenic related skin lesions. Environ Health 6:5. doi:10.1186/1476-069X-6-5 PMID:17284320 PMCID:PMC1805433

2005

  • Liu Y, Woodin MA, Hauser R, Williams PL, Herrick RF, Christiani DC, Smith TJ. 2005. Estimation of personal exposures to particulate matter and metals in boiler overhaul work. J Occup Environ Med 47(1):68-78. PMID:15643161

2004

  • McCarty KM, Senn DB, Kile ML, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC. 2004. Antimony: An unlikely confounder in the relationship between well water arsenic and health outcomes in Bangladesh. Environ Health Perspect 112(8):809-811. PMID:15175164
  • Ryan LM, Huang W, Thurston SW, Kelsey KT, Wiencke JK, Christiani DC. 2004. On the use of biomarkers for environmental health research. Stat Methods Med Res 13(3):207-225. PMID:15198487
  • Toraason M, Albertini R, Baynard S, Bigbee W, Blair AE, Boffetta P, Bonassi S, Chanock SJ, Christiani DC, Eastmond DA, Hanash S, Henry C, Kadlubar FF, Mirer F, Nebert DW, Rappaport SM, Rest K, Rothman N, Ruder AM, Savage R, Schulte PA, Siemiatycki J, Shields P, Smith MT, Tolbert PE, Vermeulen R, Vineis P, Wacholder S, Ward EM, Waters M. 2004. Applying new biotechnologies to the study of occupational cancer - A workshop summary. Environ Health Perspect 112(4):413-416. PMID:15033588

2003

  • Chen Y, Guo YL, Su HJ, Hsueh Y, Smith TJ, Ryan LM, Lee M, Chao S, Lee YY, Christiani DC. 2003. Arsenic methylation and skin cancer risk in southwestern Taiwan. J Occup Environ Med 45(3):241-248. PMID:12661181
  • Chen Y, Su HJ, Guo YL, Hsueh Y, Ryan LM, Lee M, Christiani DC. 2003. Arsenic methylation and bladder cancer risk in Taiwan. Cancer Causes Control 14(4):303-310. PMID:12846360
  • Chen Y, Xu L, Guo YL, Su HJ, Hsueh Y, Smith TJ, Ryan LM, Lee M, Chao S, Lee J, Christiani DC. 2003. Genetic polymorphisms in p53 codon 72 and skin cancer in southwestern Taiwan. J Environ Sci Health A Tox Hazard Subst Environ Eng 38(1):201-211. doi:10.1081/ESE-120016889 PMID:12635827

2002

  • Chen Y, Amarasiriwardena CJ, Hsueh Y, Christiani DC. 2002. Stability of arsenic species and insoluble arsenic in human urine. Cancer Epidemiol Biomarkers Prev 11:1427-1433. PMID:12433722
  • Cho S, Goldman MB, Ryan L, Damokosh AI, Christiani DC, Lasley BL, Wilcox AJ, Xu X. 2002. Reliability of serial urine HCG as a biomarker to detect early pregnancy loss. Hum Reprod 17(4):1060-1066. PMID:11925406

2001

  • Christiani DC, Sharp RR, Collman GW, Suk WA. 2001. Applying genomic technologies in environmental health research: challenges and opportunities. J Occup Environ Med 43:526-533. PMID:11411324
  • Hirao T, Nelson HH, Devi-Ashok T, Wain JC, Mark EJ, Christiani DC, Wiencke JK, Kelsey KT. 2001. Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer. Cancer Res 61(2):612-615. PMID:11212258
  • Kales SN, Mendoza PJ, Hill JM, Christiani DC. 2001. Spirometric surveillance in hazardous materials firefighters: does hazardous materials duty affect lung function?. J Occup Environ Med 43:1114-1120. PMID:11765682

2000

  • Chen KL, Gertig DM, Ryan LM, Willett WC, Christiani DC, Hunter DJ. 2000. Toenail arsenic levels and squamous-cell carcinoma of the skin. In: Proceedings of the Fourth International Conference on Arsenic Exposure and Health Effects. San Diego, CA.
  • Chen Y, Lee M, Su HJ, Guo YC, Hsueh Y, Christiani DC. 2000. The association between arsenic methylation ability and the risk of bladder cancer in blackfoot disease endemic area in Taiwan. In: Proceedings of the ISEE (International Society for Environmental Epidemiology)-2000 Conference. August 19-23. Buffalo, NY.
  • Duell EJ, Wiencke JK, Cheng T, Varkonyi A, Zuo Z, Devi-Ashok T, Mark EJ, Wain JC, Christiani DC, Kelsey KT. 2000. Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells. Carcinogenesis 21(5):965-971. PMID:10783319
  • Woodin MA, Liu Y, Neuberg D, Hauser R, Smith TJ, Christiani DC. 2000. Acute respiratory symptoms in workers exposed to vanadium-rich fuel-oil ash. Am J Ind Med 37(4):353-363. PMID:10706747
  • Woodin MA, Liu Y, Neuberg D, Hauser R, Smith TJ, Christiani DC. 2000. Pulmonary function in workers exposed to low levels of fuel-oil ash. Am J Respir Crit Care Med 161:A235.
  • Wu MT, Demple B, Bennett RA, Christiani DC, Fan R, Hu H. 2000. Individual variability in the zinc inducibility of metallothionein-IIA mRNA in human lymphocytes. J Toxicol Environ Health A 61(7):553-567. PMID:11127411

1999

  • Chen KL, Amarasiriwardena CJ, Christiani DC. 1999. Determination of total arsenic concentrations in nails by inductively coupled plasma mass spectrometry. Biol Trace Elem Res 67:109-125. PMID:10073418
  • Chen KL, Guo YL, Su HJ, Lee J, Chao S, Christiani DC. 1999. Arsenic exposure, solar radiation, and risk of skin cancer. Epidemiology 10:S35.
  • Chong I, Shi MM, Love JA, Christiani DC, Paulauskis JD. 1999. Regulation of chemokine mRNA expression in vanadium-induced lung inflammation. Am J Respir Crit Care Med 159(3):A511.
  • Guo YL, Su HJ, Chen KL, Christiani DC. 1999. Exposure to arsenic is associated with hospital controls of bladder cancer but not community controls. Epidemiology 10:S35.
  • Nelson HH, Christiani DC, Mark EJ, Wiencke JK, Wain JC, Kelsey KT. 1999. Implications and prognostic value of K-ras mutation for early-stage lung cancer in women. J Natl Cancer Inst 91(23):2032-2038. PMID:10580029
  • Nelson HH, Christiani DC, Wiencke JK, Mark EJ, Wain JC, Kelsey KT. 1999. K-ras mutation and occupational asbestos exposure in lung adenocarcinoma: asbestos-related cancer without asbestosis. Cancer Res 59:4570-4573. PMID:10493509
  • Wang X, Christiani DC, Mark EJ, Nelson HH, Wiencke JK, Gunn L, Wain JC, Kelsey KT. 1999. Carcinogen exposure, p53 alteration and K-ras mutation in synchronous multiple primary lung carcinoma. Cancer 85(8):1734-1739. PMID:10223567
  • Wiencke JK, Thurston SW, Kelsey KT, Varkonyi A, Wain JC, Mark EJ, Christiani DC. 1999. Early age at smoking initiation and tobacco carcinogen DNA damage in the lung. J Natl Cancer Inst 91(7):614-619. PMID:10451453
  • Wiencke JK, Varkonyi A, Kelsey KT, Wain JC, Mark EJ, Christiani DC. 1999. Polyphenol-related DNA adducts in blood mononuclear cells are increased in newly diagnosed patients with lung cancer. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999.
  • Wiencke JK, Varkonyi A, Semey K, Levay G, Wain JC, Mark EJ, Kelsey KT, Christiani DC. 1999. Detection of benzene-related DNA adducts in human tissues and evidence of co-activation with polyaromatic hydrocarbons (PAHs). In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.135.
  • Wiencke JK, Varkonyi A, Semey K, Levay G, Wain JC, Mark EJ, Kelsey KT, Christiani DC. 1999. Validation of blood mononuclear cell DNA-adducts as a marker of DNA damage in human lung. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.283.
  • Woodin MA, Liu Y, Hauser R, Smith TJ, Christiani DC. 1999. Pulmonary function in workers exposed to low levels of fuel-oil ash. J Occup Environ Med 41(11):973-980. PMID:10570503
  • Wu MT, Pan BJ, Ho CK, Lin SF, Kao CY, Chang TT, Wong YC, Hsien KS, Huang CB, Liu CL, Wang YC, Christiani DC. 1999. Petrochemical exposure and leukemia - a preliminary study. Epidemiology 10:S35.

1998

  • Donovan CE, Mark DA, Nass RK, Shen MF, Krinzman SJ, Kobzik L, Drazen JM, Christiani DC, Perkins DL, Finn PW. 1998. Blockade of B7 costimulatory molecules inhibits airway hyperresponsiveness in a murine model. Am J Respir Crit Care Med 155:A541.
  • Guo YL, Su HJ, Huang JD, Cheng YW, Christiani DC. 1998. NAT2 polymorphism, arsenic exposure and bladder cancer. Pharmacogenet Genomics 8:187-190.
  • Hauser R, Elreedy S, Ryan PB, Christiani DC. 1998. Urine vanadium concentrations in workers overhauling an oil-fired boiler. Am J Ind Med 33:55-61. PMID:9408529
  • Kodavanti UP, Hauser R, Christiani DC, Meng ZH, McGee J, Ledbetter AD, Richards J, Costa DL. 1998. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals. Toxicol Sci 43:204-212. PMID:9710962
  • Lee BW, Wain JC, Kelsey KT, Wiencke JK, Christiani DC. 1998. Association of cigarette smoking and asbestos exposure with location and histology of lung cancer. Am J Respir Crit Care Med 157:748-755. PMID:9517586
  • Nelson HH, Wiencke JK, Gunn L, Wain JC, Christiani DC, Kelsey KT. 1998. Chromosome 3p14 alterations in lung cancer: evidence that FHIT exon deletion is a target of tobacco carcinogens and asbestos. Cancer Res 58(9):1804-1807. PMID:9581816
  • Woodin MA, Hauser R, Liu Y, Smith TJ, Siegel PD, Lewis DM, Tollerud DJ, Christiani DC. 1998. Molecular markers of acute upper airway inflammation in workers exposed to fuel-oil ash. Am J Respir Crit Care Med 158:182-187. PMID:9655727
  • Xu X, Wiencke JK, Niu T, Wang M, Watanabe H, Kelsey KT, Christiani DC. 1998. Benzene exposure, glutathione S-transferase theta homozygous deletion and sister chromatid exchanges. Am J Ind Med 33(2):157-163. PMID:9438048

1997

  • Cho S, Hauser R, Christiani DC. 1997. Reproducibility of nasal peak inspiratory flow among healthy adults: assessment of epidemiologic utility. Chest 112(6):1547-1553. PMID:9404752
  • Kales SN, Polykronopoulos GN, Castro MJ, Goldman RH, Christiani DC. 1997. Injuries caused by hazardous materials accidents. Ann Emerg Med 30(5):598-603. PMID:9360568
  • Kales SN, Polykronopoulos GN, Castro MJ, Goldman RH, Christiani DC. 1997. Mechanisms of and facility types involved in hazardous materials incidents. Environ Health Perspect 105(9):998-1000. PMID:9300926
  • Kelsey KT, Ross D, Traver RD, Christiani DC, Zuo Z, Spitz MR, Wang M, Xu X, Lee BK, Schwartz BS, Wiencke JK. 1997. Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy. Br J Cancer 76(7):852-854. doi:10.1038/bjc.1997.474 PMID:9328142
  • Meng ZH, Costa DL, Hauser R, Christiani DC. 1997. Lung injury, leachable metals, and oxidation potential of fly ash. Am J Respir Crit Care Med 155:A244.
  • Minnich MG, Houk RS, Woodin MA, Christiani DC. 1997. Method to screen urine samples for vanadium by inductively coupled plasma mass spectrometry with cryogenic desolvation. J Anal At Spectrom 12:1345-1350.
  • Woodin MA, Hauser R, Liu Y, Smith TJ, Christiani DC. 1997. Respiratory symptom incidence in workers overhauling an oil-fired boiler. Am J Respir Crit Care Med 155:A811.
  • Wu MT, Kelsey KT, Mao IF, Wypij D, Liu H, Christiani DC. 1997. Elevated serum liver enzymes in coke-oven and by-product workers. J Occup Environ Med 39:527-534. PMID:9211210
  • Wu MT, Mao IF, Wypij D, Ho CK, Chen JR, Christiani DC. 1997. Serum liver function profiles in coking workers. Am J Ind Med 32:478-486. PMID:9327071

1996

  • Cernadas M, DeSanctis GT, Krinzman SJ, Hikutani H, Christiani DC, Perkins DL, Finn PW. 1996. Anti-CD23 inhibits airway reactivity and augments lymphocyte activation in a murine asthma model. Am J Respir Crit Care Med 153:A811.
  • Hauser R, Daskalakis C, Christiani DC. 1996. A regression approach to the analysis of serial peak-flow among fuel-oil ash-exposed workers. Am J Respir Crit Care Med 154:968-974. PMID:8887594
  • Hauser R, Godleski J, Hatch V, Christiani DC. 1996. Ultrafine particles in human lung macrophages and their relationship with lung function. Am J Respir Crit Care Med 153:A544.
  • Krinzman SJ, DeSanctis GT, Cernadas M, Kobzik L, Christiani DC, Perkins DL, Finn PW. 1996. T-cell activation in a murine model of asthma. American Journal of the Physiology of the Lung 271:L476-L483. PMID:8843798
  • Woodin MA, Hauser R, Siegel RD, Tollerud DJ, Lewis DM, Liu Y, Smith TJ, Christiani DC. 1996. Nasal lavage inflammatory mediators as biomarkers of upper airway exposure to fuel oil ash. Am J Respir Crit Care Med 153:A475.

1995

  • Hauser R, Elreedy S, Hoppin JA, Christiani DC. 1995. Airway obstruction in boilermakers exposed to fuel-oil ash: a prospective investigation. Am J Respir Crit Care Med 152:1478-1484. PMID:7582280
  • Hauser R, Elreedy S, Hoppin JA, Christiani DC. 1995. Upper airway response in workers exposed to fuel-oil ash: nasal lavage analysis. J Occup Environ Med 52:353-358. PMID:7795759
  • Nelson HH, Wiencke JK, Christiani DC, Cheng T, Zuo Z, Schwartz BS, Lee B, Spitz MR, Wang M, Xu X, Kelsey KT. 1995. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis 16(5):1243-1246. PMID:7767992
  • Wiencke JK, Kelsey KT, Varkonyi A, Semey K, Wain JC, Mark EJ, Christiani DC. 1995. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung. Cancer Res 55(21):4910-4914. PMID:7585529
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