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Your Environment. Your Health.

Person Details: Larry W. Robertson

Superfund Research Program

Larry W. Robertson

University of Iowa
UI Research Park #219 IREH
Iowa City, Iowa 52242-5000
Phone: 319-335-4554
Fax: 319-335-4290
Email: larry-robertson@uiowa.edu

Projects

Research Briefs

Publications

2019

  • Gourronc FA, Perdew GH, Robertson LW, Klingelhutz AJ. 2019. PCB126 blocks the thermogenic beiging response of adipocytes. Environ Sci Pollut Res Int PMID:31721030
  • Klenov V, Flor S, Adur M, Ganesan S, Eti N, Iqbal K, Soares M, Ludewig G, Ross J, Keating A, Robertson LW. 2019. Uterine toxicity following exposure to polychlorinated biphenyl 126 is mediated by the aryl hydrocarbon receptor. Fertil Steril 111(4):e4. doi:10.1016/j.fertnstert.2019.02.038

2018

  • Dhakal K, Gadupudi GS, Lehmler H, Ludewig G, Duffel MW, Robertson LW. 2018. Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environ Sci Pollut Res Int 25:16277-16290. doi:10.1007/s11356-017-9694-x PMID:28744683 PMCID:PMC5785587
  • Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW. 2018. PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver. Toxicol Sci 163:440-453. doi:10.1093/toxsci/kfy041 PMID:29474705 PMCID:PMC5974782
  • Gourronc FA, Robertson LW, Klingelhutz AJ. 2018. A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environ Sci Pollut Res Int 25:16481-16492. doi:10.1007/s11356-017-9676-z PMID:28699004 PMCID:PMC5764822
  • Klaren WD, Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427-16433. doi:10.1007/s11356-017-0202-0 PMID:28940161 PMCID:PMC5866157
  • Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler H. 2018. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int 25(17):1-14. doi:10.1007/s11356-017-1162-0 PMID:29322390 PMCID:PMC6015536
  • Parker VS, Squirewell EJ, Lehmler H, Robertson LW, Duffel MW. 2018. Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environ Toxicol Pharmacol 58:196-201. doi:10.1016/j.etap.2018.01.010 PMID:29408762 PMCID:PMC6078096
  • Robertson LW, Weber R, Nakano T, Johansson N. 2018. PCBs risk evaluation, environmental protection, and management: 50-year research and counting for elimination by 2028. Environ Sci Pollut Res Int 25:16269-16276. doi:10.1007/s11356-018-2467-3 PMID:29934860 PMCID:PMC6033322
  • Rodriguez EA, Vanle BC, Doorn JA, Lehmler H, Robertson LW, Duffel MW. 2018. Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environ Toxicol Pharmacol 62:69-78. doi:10.1016/j.etap.2018.06.010 PMID:29986280 PMCID:PMC609219

2017

2016

  • Ekuase EJ, van't Erve TJ, Rahaman A, Robertson LW, Duffel MW, Luthe G. 2016. Mechanistic insights into the specificity of human cytosolic sulfotransferase 2A1 (hSULT2A1) for hydroxylated polychlorinated biphenyls through the use of fluoro-tagged probes. Environ Sci Pollut Res Int 23(3):2119-2127. doi:10.1007/s11356-015-4886-8 PMID:26165989 PMCID:PMC4713379
  • Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. 2016. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Toxicol Sci 149(1):98-110. doi:10.1093/toxsci/kfv215 PMID:26396156 PMCID:PMC4731404
  • Gadupudi GS, Klingelhutz AJ, Robertson LW. 2016. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis and glycogenolysis in PCB126 hepatotoxicity. Chem Res Toxicol 29(9):1504-1509. doi:10.1021/acs.chemrestox.6b00172 PMID:27509375
  • Hunt G, Stegeman JJ, Robertson LW. 2016. PCBs: exposures, effects, remediation, and regulation with special emphasis on PCBs in schools. Environ Sci Pollut Res Int 23(3):1971-1974. doi:10.1007/s11356-015-5774-y PMID:26620856 PMCID:PMC4718839
  • Klaren WD, Flor S, Gibson-Corley KN, Ludewig G, Robertson LW. 2016. Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption. Toxicol Rep 3:21-28. doi:10.1016/j.toxrep.2015.12.001 PMID:26770886 PMCID:PMC4710377
  • Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. 2016. Assessment of the mitigative capacity of dietary zinc on PCB126 hepatotoxicity and the contribution of zinc to toxicity. Chem Res Toxicol 29(5):851-859. doi:10.1021/acs.chemrestox.6b00022 PMID:26967026 PMCID:PMC5100827
  • Li M, Teesch LM, Murry DJ, Pope RM, Li Y, Robertson LW, Ludewig G. 2016. Cytochrome c adducts with PCB quinoid metabolites. Environ Sci Pollut Res Int 23(3):2148-2159. doi:10.1007/s11356-015-4801-3 PMID:26062463 PMCID:PMC4676959
  • Portier CJ, Armstrong BK, Baguley B, Baur X, Belyaev I, Belle R, Belpoggi F, Biggeri A, Bosland MC, Bruzzi P, Budnik L, Bugge M, Burns K, Calaf GM, Carpenter DO, Carpenter H, Lopez-Carillo L, Clapp R, Cocco P, Consonni D, Comba P, Craft ES, Dalvie M, Davis D, Demers PA, De Roos AJ, DeWitt JT, Forastiere F, Freedman JH, Fritschi L, Gaus C, Gohlke J, Goldberg M, Greiser E, Hansen J, Hardell L, Hauptmann M, Huang W, Huff J, James MO, Jameson C, Kortenkamp A, Kopp-Schneider A, Kromhout H, Larramendy M, Landrigan PJ, Lash LH, Leszczynski D, Lynch CF, Magnani C, Mandrioli D, Martin FL, Merler E, Michelozzi P, Miligi L, Miller A, Mirabelli D, Mirer F, Naidoo S, Perry MJ, Petronio M, Pirastu R, Portier R, Ramos KS, Robertson LW, Rodriguez T, Roosli M, Ross M, Roy D, Rusyn I, Saldiva P, Sass J, Savolainen K, Scheepers P, Sergi C, Silbergeld EK, Smith MT, Stewart BW, Sutton P, Tateo F, Terracini B, Thielmann H, Thomas DB, Vainio H, Vena J, Vineis P, Weiderpass E, Weisenburger DD, Woodruff TJ, Yorifuji T, Yu I, Zambon P, Zeeb H, Zhou SF. 2016. Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). J Epidemiol Community Health 70(8):741-745. doi:10.1136/jech-2015-207005 PMID:26941213 PMCID:PMC4975799
  • Rodriguez EA, Li X, Lehmler H, Robertson LW, Duffel MW. 2016. Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin. Environ Sci Technol 50(10):5320-5327. doi:10.1021/acs.est.6b00484 PMID:27116425 PMCID:PMC4883002
  • Shen H, Robertson LW, Ludewig G. 2016. Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3. Environ Sci Pollut Res Int 23(3):2108-2118. doi:10.1007/s11356-015-4722-1 PMID:26006071 PMCID:PMC4662644
  • Wang B, Klaren WD, Wels B, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. 2016. Dietary manganese modulates PCB126 toxicity, metal status, and MnSOD in the rat. Toxicol Sci 150(1):15-26. doi:10.1093/toxsci/kfv312 PMID:26660635 PMCID:PMC5009614
  • Wangpradit O, Adamcakova-Dodd A, Heitz K, Robertson LW, Thorne PS, Luthe G. 2016. PAMAM dendrimers as nano carriers to investigate inflammatory responses induced by pulmonary exposure of PCB metabolites in Sprague-Dawley rats. Environ Sci Pollut Res Int 23(3):2128-2137. doi:10.1007/s11356-015-5022-5 PMID:26400242 PMCID:PMC4803647
  • Wangpradit O, Rahaman A, Mariappan S, Buettner GR, Robertson LW, Luthe G. 2016. Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids. Environ Sci Pollut Res Int 23(3):2138-2147. doi:10.1007/s11356-015-5007-4 PMID:26396011 PMCID:PMC4767158
  • Wu X, Yang J, Morisseau C, Robertson LW, Hammock BD, Lehmler H. 2016. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats. Toxicol Sci 152(2):309-322. doi:10.1093/toxsci/kfw084 PMID:27208083 PMCID:PMC4960907

2015

  • Agudo A, Aronson KJ, Bonefeld-Jørgensen EC, Cocco P, Cogliano VJ, Cravedi J, Esch HL, Fiedler H, Glauret HP, Guo YL, Herbert RA, Hopf NB, James MO, Johansson N, Le Bizec B, Ludewig G, Machala M, Merletti F, Narbonne J, Robertson LW, Ruder AM, Tryphonas H, Vermeulen R, Vorkamp K, Walker N. 2015. IARC monographs on the evaluation of carcinogenic risks to humans, volume 107, Polychlorinated biphenyls and polybrominated biphenyls. http://monographs.iarc.fr/ENG/Monographs/vol107/mono107.pdf
  • Gadupudi GS, Gourronc FA, Ludewig G, Robertson LW, Klingelhutz AJ. 2015. PCB126 inhibits adipogenesis of human preadipocytes. Toxicol In Vitro 29(1):132-141. doi:10.1016/j.tiv.2014.09.015 PMID:25304490 PMCID:PMC4250299
  • Grimm FA, He X, Teesch LM, Lehmler H, Robertson LW, Duffel MW. 2015. Tissue distribution, metabolism, and excretion of 3,3'-dichloro-4'-sulfooxy-biphenyl in the rat. Environ Sci Technol 49(13):8087-8095. doi:10.1021/acs.est.5b01499 PMID:26046945 PMCID:PMC4496304
  • Grimm FA, Hu D, Kania-Korwel I, Lehmler H, Ludewig G, Hornbuckle KC, Duffel MW, Bergman A, Robertson LW. 2015. Metabolism and metabolites of polychlorinated biphenyls. Crit Rev Toxicol 45(3):245-272. doi:10.3109/10408444.2014.999365 PMID:25629923 PMCID:PMC4383295
  • Grimm FA, Lehmler H, He X, Robertson LW, Duffel MW. 2015. Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models. Chem Biol Interact 228:1-8. doi:10.1016/j.cbi.2015.01.002 PMID:25595224 PMCID:PMC4327905
  • Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Robertson LW. 2015. Progression of micronutrient alteration and hepatotoxicity following acute PCB126 exposure. Toxicology 338:1-7. doi:10.1016/j.tox.2015.09.004 PMID:26410179 PMCID:PMC4658301

2014

2013

  • Dhakal K, Adamcakova-Dodd A, Lehmler H, Thorne PS, Robertson LW. 2013. Sulfate conjugates are urinary markers of inhalation exposure to 4-chlorobiphenyl (PCB3). Chem Res Toxicol 26(6):853-855. doi:10.1021/tx4001539 PMID:23713983 PMCID:PMC3703249
  • Grimm FA, Lehmler H, He X, Robertson LW, Duffel MW. 2013. Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environ Health Perspect 121(6):657-662. doi:10.1289/ehp.1206198 PMID:23584369 PMCID:PMC3672920
  • Lai IK, Klaren WD, Li M, Wels B, Simmons DL, Olivier AK, Haschek-Hock WM, Wang K, Ludewig G, Robertson LW. 2013. Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver?. Chem Res Toxicol 26(5):634-644. doi:10.1021/tx400049s PMID:23527585 PMCID:PMC3660509
  • Ludewig G, Robertson LW. 2013. Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma. Cancer Lett 334(1):46-55. doi:10.1016/j.canlet.2012.11.041 PMID:23211541 PMCID:PMC3648605
  • Ludewig G, Robertson LW, Glauert HP. 2013. Carcinogenicity and Mechanisms of Persistent Organic Pollutants. In: Effects of Persistent and Bioactive Organic Pollutants on Human Health. pp.57-100.
  • Qin X, Lehmler H, Teesch LM, Robertson LW, Duffel MW. 2013. Chlorinated biphenyl quinones and phenyl- 2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1. Chem Res Toxicol 26(10):1474-1485. doi:10.1021/tx400207q PMID:24059442 PMCID:PMC3846294
  • Rignall B, Grote K, Gavrilov A, Weimer M, Kopp-Schneider A, Krause E, Appel KE, Buchmann A, Robertson LW, Lehmler H, Kania-Korwel I, Chahoud I, Schwarz M. 2013. Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment. Toxicol Sci 133(1):29-41. doi:10.1093/toxsci/kft034 PMID:23457121 PMCID:PMC3627557
  • Svensson RU, Bannick NL, Marin MJ, Robertson LW, Lynch CF, Henry MD. 2013. Chronic chlorpyrifos exposure does not promote prostate cancer in prostate specific PTEN mutant mice. J Environ Pathol Toxicol Oncol 32(1):29-39. doi:10.1615/JEnvironPatholToxicolOncol.2013006778 PMID:23758150 PMCID:PMC3951157
  • Zhu Y, Mapuskar KA, Marek RF, Xu W, Lehmler H, Robertson LW, Hornbuckle KC, Spitz DR, Aykin-Burns N. 2013. A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3,3'-dichlorobiphenyl (PCB11). Toxicol Sci 136(1):39-50. doi:10.1093/toxsci/kft186 PMID:23997111 PMCID:PMC3829572

2012

2011

  • Bunaciu RP, Tharappel JC, Lehmler H, Lee EY, Robertson LW, Bruckner GG, Spear BT, Glauert HP. 2011. Role of oil vehicle on hepatic cell proliferation in PCB-treated rats. J Environ Pathol Toxicol Oncol 30(4):273-282. PMID:22181977 PMCID:PMC3522147
  • Ekuase EJ, Liu Y, Lehmler H, Robertson LW, Duffel MW. 2011. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chem Res Toxicol 24:1720-1728. doi:10.1021/tx200260h PMID:21913674 PMCID:PMC3196794
  • Lai IK, Chai Y, Simmons DL, Watson WH, Tan R, Haschek-Hock WM, Wang K, Wang B, Ludewig G, Robertson LW. 2011. Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats. Toxicol Sci 124:202-214. doi:10.1093/toxsci/kfr215 PMID:21865291 PMCID:PMC3196656
  • Liu Y, Lehmler H, Robertson LW, Duffel MW. 2011. Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chem Biol Interact 189:153-160. doi:10.1016/j.cbi.2010.11.009 PMID:21130751 PMCID:PMC3032042
  • Robertson LW, Ludewig G. 2011. Polychlorinated biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs. Gefahrst Reinhalt Luft 71(1-2):25-32. PMID:21686028 PMCID:PMC3113507
  • Senthilkumar PK, Klingelhutz AJ, Jacobus JA, Lehmler H, Robertson LW, Ludewig G. 2011. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicol Lett 204:64-70. doi:10.1016/j.toxlet.2011.04.012 PMID:21530622 PMCID:PMC3109099
  • Song Y, Ambati J, Parkin S, Rankin S, Robertson LW, Lehmler H. 2011. Crystal structure and density functional theory studies of toxic quinone metabolites of polychlorinated biphenyls. Chemosphere 85:386-392. doi:10.1016/j.chemosphere.2011.07.004 PMID:21824639 PMCID:PMC3206982
  • Wang B, Robertson LW, Wang K, Ludewig G. 2011. Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126. Xenobiotica 41:1031-1043. doi:10.3109/00498254.2011.603763 PMID:21970748 PMCID:PMC3564674

2010

2009

  • Klosener J, Peters TM, Adamcakova-Dodd A, Teesch LM, Thorne PS, Robertson LW, Luthe G. 2009. Innovative application of fluoro tagging to trace airborne particulate and gas-phase polybrominated diphenyl ether exposures. Chem Res Toxicol 22(1):179-186. doi:10.1021/tx8003032 PMID:19111055 PMCID:PMC3120107
  • Pessah IN, Lehmler H, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. 2009. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chem Res Toxicol 22(1):201-207. doi:10.1021/tx800328u PMID:18954145 PMCID:PMC2662366
  • Spencer W, Lehmler H, Robertson LW, Gupta RC. 2009. Oxidative DNA adducts following Cu2+-mediated activation of dihydroxy PCBs: role of reactive oxygen species. Free Radic Biol Med 46(10):1346-1352. doi:10.1016/j.freeradbiomed.2009.02.005 PMID:19233261 PMCID:PMC2744390
  • Wangpradit O, Teesch LM, Mariappan S, Duffel MW, Norstrom K, Robertson LW, Luthe G. 2009. Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase. Chem Res Toxicol 22(1):64-71. doi:10.1021/tx800300t PMID:19105592 PMCID:PMC2637223
  • Yang-won S, Buettner GR, Venkataraman S, Treimer S, Robertson LW, Ludewig G. 2009. UVA/B-induced formation of free radicals from decabromodiphenyl ether. Environ Sci Technol 43(7):2581-2588. PMID:19452920 PMCID:PMC2685467

2008

  • Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler H, Lee EY, Robertson LW, Spear BT. 2008. Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. Toxicol Appl Pharmacol 232(2):302-308. doi:10.1016/j.taap.2008.06.013 PMID:18644402 PMCID:PMC2583134
  • Glauert HP, Tharappel JC, Lu Z, Stemm DN, Banerjee S, Chan L, Lee EY, Lehmler H, Robertson LW, Spear BT. 2008. Role of oxidative stress in the promoting activities of pcbs. Environ Toxicol Pharmacol 25(2):247-250. doi:10.1016/j.etap.2007.10.025 PMID:19122744 PMCID:PMC2836878
  • Jacobus JA, Flor S, Klingelhutz AJ, Robertson LW, Ludewig G. 2008. 2-(4'-Chlorophenyl)-1,4-benxoquinone increases the frequency of micronuclei and shortens telomeres. Environ Toxicol Pharmacol 25(2):267-272. doi:10.1016/j.etap.2007.10.022 PMID:18438462 PMCID:PMC2346440
  • Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler H. 2008. Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. Environ Toxicol Chem 27(2):299-305. doi:10.1897/07-359R.1 PMID:18348647
  • Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler H. 2008. Influence of dietary fat on the enantioselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in female mice. Food Chem Toxicol 46(2):637-644. doi:10.1016/j.fct.2007.09.072 PMID:17950514 PMCID:PMC2289907
  • Kania-Korwel I, Xie W, Hornbuckle KC, Robertson LW, Lehmler H. 2008. Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes. Arch Environ Contam Toxicol 55(3):510-517. doi:10.1007/s00244-007-9111-4 PMID:18437444
  • Klosener J, Swenson DC, Robertson LW, Luthe G. 2008. Effects of fluoro substitution on 4-bromodiphenyl ether (PBDE 3). Acta Crystallogr B 64(Pt1):108-119. doi:10.1107/S0108768107067079 PMID:18204217 PMCID:PMC3120100
  • Ludewig G, Lehmann L, Esch HL, Robertson LW. 2008. Metabolic activation of PCBs to carcinogens in vivo - a review. Environ Toxicol Pharmacol 25(2):241-246. doi:10.1016/j.etap.2007.10.029 PMID:18452002 PMCID:PMC2364599
  • Luthe G, Boy R, Jacobus JA, Smith B, Rahaman A, Robertson LW, Ludewig G. 2008. Xenobiotic geometry and media pH determine cytotoxicity through solubility. Chem Res Toxicol 21(5):1017-1027. doi:10.1021/tx700214p PMID:18402468
  • Luthe G, Jacobus JA, Robertson LW. 2008. Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: a theoretical Structure-activity assessment. Environ Toxicol Pharmacol 25(2):202-210. doi:10.1016/j.etap.2007.10.017 PMID:19768137 PMCID:PMC2746664
  • Ravoori S, Ayotte P, Srinivasan C, Pereg D, Robertson LW, Gupta RC, Jeyabalan J. 2008. DNA damage associated with PCBs in the whole blood cells of Inuit. Environ Toxicol Pharmacol 25(2):273-276. PMID:21783863
  • Sacco JC, Lehmler H, Robertson LW, Li W, James MO. 2008. Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine. Drug Metab Dispos 36(4):623-630. doi:10.1124/dmd.107.019596 PMID:18180271
  • Song Y, Buettner GR, Parkin S, Wagner BA, Robertson LW, Lehmler H. 2008. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. J Org Chem 73(21):8296-8304. doi:10.1021/jo801397g PMID:18839991 PMCID:PMC2629131
  • Stemm DN, Tharappel JC, Lehmler H, Srinivasan C, Morris J, Spate VL, Robertson LW, Spear BT, Glauert HP. 2008. Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. Exp Biol Med (Maywood) 233(3):366-376. doi:10.3181/0708-RM-211 PMID:18296742
  • Tharappel JC, Lehmler H, Srinivasan C, Robertson LW, Spear BT, Glauert HP. 2008. Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food Chem Toxicol 46(11):3467-3474. doi:10.1016/j.fct.2008.08.023 PMID:18796325 PMCID:PMC2597727
  • Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler H, Goswami PC. 2008. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med 45(8):1094-1102. doi:10.1016/j.freeradbiomed.2008.07.007 PMID:18691649 PMCID:PMC2614346

2007

  • Bunaciu RP, Tharappel JC, Lehmler H, Kania-Korwel I, Robertson LW, Srinivasan C, Spear BT, Glauert HP. 2007. The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. Toxicology 239(3):147-55. PMID:17703865
  • Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler H. 2007. Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. Chirality 19(1):56-66. doi:10.1002/chir.20342 PMID:17089340
  • Lehmann L, Esch HL, Kirby PA, Robertson LW, Ludewig G. 2007. 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats. Carcinogenesis 28(2):471-478. doi:10.1093/carcin/bgl157 PMID:16950798
  • Ludewig G, Esch HL, Robertson LW. 2007. Polyhalogenierte Bi- und Terphenyle. Chapter 20 in: Handbuch der Lebensmitteltoxikologie. Wiley-VCH Weinheim, Germany. pp.1031-1094.
  • Luthe G, Swenson DC, Robertson LW. 2007. Influence of fluoro-substitution on the planarity of 4-chlorobiphenyl (PCB 3). Acta Crystallogr B 63:319-327. PMID:17374943
  • Robertson LW, Berberian I, Borges T, Chen L, Chow CK, Glauert HP, Filser J, Thomas H. 2007. Suppression of peroxisomal enzyme activities and cytochrome P450 4A isozyme expression by congeneric polybrominated and polychlorinated biphenyls. PPAR Res 2007:15481. doi:10.1155/2007/15481 PMID:18274624 PMCID:PMC2220027
  • Sadeghi-aliabadi H, Chan K, Lehmler H, Robertson LW, O-Brian PJ. 2007. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chem Biol Interact 167:184-192. PMID:17408604
  • Zettner M, Flor S, Ludewig G, Wagner J, Robertson LW, Lehmann L. 2007. Quinoid metabolites of 4-monochlorobiphenyl (PCB3) induce gene mutations in cultured Chinese hamster V79 Cells. Toxicol Sci 100:88-98. PMID:17686921

2006

  • Bender RP, Lehmler H, Robertson LW, Ludewig G, Osheroff N. 2006. Polychlorinated biphenyl quinone mtabolites Poison human topoisomerase II: Altering enzyme function by blocking the N-terminal protein gate. Biochemistry 45(33):10140-10152. PMID:16906772
  • Kania-Korwel I, Garrison AW, Avants JK, Hornbuckle KC, Robertson LW, Sulkowski WW, Lehmler H. 2006. Distribution of chiral PCBs in selected tissues in the laboratory rat. Environ Sci Technol 40(12):3704-3710. PMID:16830530
  • Kunz S, Schwarz M, Schilling B, Papke O, Lehmler H, Robertson LW, Schrenk D, Schmitz H. 2006. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicol Lett 164(2):133-143. PMID:16426774
  • Liu Y, Apak TI, Lehmler H, Robertson LW, Duffel MW. 2006. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chem Res Toxicol 19(11):1420-1425. PMID:17112228
  • Luthe G, Leonards PE, Reijerink GS, Liu H, Johansen JS, Robertson LW. 2006. Monofluorinated analogues of polybrominated diphenyl ethers as analytical standards: synthesis, NMR, and GC-MS characterization and molecular orbital studies. Environ Sci Technol 40(9):3023-3029. PMID:16719106
  • Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler H, Robertson LW, Gregoraszczuk EL. 2006. Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicol Lett 166(3):200-211. PMID:16949219
  • Ptak A, Ludewig G, Robertson LW, Lehmler H, Gregoraszczuk EL. 2006. In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: Effects on sex hormone levels and aromatase activity. Toxicol Lett 164(2):113-122. PMID:16412591
  • Strathmann J, Schwarz M, Tharappel JC, Glauert HP, Spear BT, Robertson LW, Appel KE, Buchmann A. 2006. PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors. Toxicol Sci 93(1):34-40. doi:10.1093/toxsci/kfl041 PMID:16782779
  • Vyas SM, Parkin S, Robertson LW, Lehmler H. 2006. 2,5-Dichloro-4'-methoxybiphenyl. Acta Crystallogr B E62,Part9:o4162-o4163.
  • Vyas SM, Parkin S, Robertson LW, Lehmler H. 2006. 4-Chloro-2',3'-dimethoxybiphenyl. Acta Crystallogr B E62,Part9:o3639-o3640.
  • Wang L, Lehmler H, Robertson LW, James MO. 2006. Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate. Chem Biol Interact 159(3):235-246. PMID:16413005

2005

  • Espandiari P, Robertson LW, Srinivasan C, Glauert HP. 2005. Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology 206(3):373-381. PMID:15588927
  • Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler H, Lee EY, Robertson LW, Spear BT. 2005. Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats. J Nutr 135(2):283-286. PMID:15671227
  • Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart EJ, Robertson LW. 2005. Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor. Environ Health Perspect 113(1):83-87. PMID:15626652 PMCID:PMC1253714
  • Hennig B, Toborek M, Ramadass P, Ludewig G, Robertson LW, Arif JM. 2005. Polychlorinated biphenyls, oxidative stress and diet. Chapter Vol. 3 in: Reviews in Food and Nutrition Toxicity. CRC Press, Inc., Boca Raton, DE. pp.93-128.
  • Wang L, Lehmler H, Robertson LW, James MO. 2005. In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols. Environ Health Perspect 113(6):680-687. PMID:15929889 PMCID:PMC1257591

2004

  • Espandiari P, Glauert HP, Lehmler H, Lee EY, Srinivasan C, Robertson LW. 2004. Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicol Sci 79(1):41-46. PMID:14976334
  • Gauger KJ, Kato Y, Haraguchi K, Lehmler H, Robertson LW, Bansal R, Zoeller RT. 2004. Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors. Environ Health Perspect 112(5):516-523. PMID:15064154
  • Hennig B, Reiterer G, Toborek M, Daugherty A, Smart EJ, Matveev SV, Robertson LW. 2004. Dietary fat interacts with PCBs to induce changes in lipid metabolism in LDL receptor deficient mice. Organohalogen Compounds 66:2903-2906.
  • Hennig B, Toborek M, Robertson LW. 2004. Proinflammatory mechanisms of PCB toxicity in the vascular endothelium. In: Proceedings of the 43rd Annual Meeting of the Society of Toxicology (SOT), March 21-25, 2004. Baltimore, MD.
  • Lu Z, Lee EY, Robertson LW, Glauert HP, Spear BT. 2004. Effect of 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB-153) on Hepatocyte Proliferation and Apoptosis in Mice Deficient in the p50 Subunit of the Transcription Factor NF-B. Toxicol Sci 81(1):35-42.
  • Machala M, Blaha L, Lehmler H, Pliskova M, Majkova Z, Kapplova P, Sovadinova I, Vondracek J, Malmberg T, Robertson LW. 2004. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells. Chem Res Toxicol 17(3):340-347. doi:10.1021/tx030034v PMID:15025504
  • Stemm DN, Robertson LW, Tharappel JC, Glauert HP. 2004. Effects of 3,3',4,4'-tetrachlorobiphenyl (PCB 77) on the distribution and metabolism of selenium in rats. In: Proceedings of the 43rd Annual Meeting of the Society of Toxicology (SOT), March 21-25, 2004. Baltimore, MD.

2003

  • Arif JM, Lehmler H, Robertson LW, Gupta RC. 2003. Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro. Chem Biol Interact 142(3):307-316. PMID:12453668
  • Bunaciu RP, Robertson LW, Spear BT, Glauert HP. 2003. Effect of inhibition of Kupffer cell activation by dietary glycine on hepatic cell proliferation in rats. FASEB J 17(5):A1165Part2Suppl.S.
  • Choi W, Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M. 2003. PCB 104 induces oxidative stress and stimulates proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis. FASEB J 17:A272.
  • Choi W, Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M. 2003. PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis. Toxicol Sci 75(1):47-56. doi:10.1093/toxsci/kfg149 PMID:12805654
  • Espandiari P, Glauert HP, Lehmler H, Lee EY, Srinivasan C, Robertson LW. 2003. Polychlorinated biphenyls (PCBs) as initiators in liver carcinogensis: resistant hepatocyte model. Toxicol Appl Pharmacol 186(1):55-62. PMID:12583993
  • Espandiari P, Lehmler H, Stemm DN, Glauert HP, Robertson LW. 2003. PCB metabolites as initiating agents in hepatocarcinogenesis. Toxicol Sci 72(S-1):1145.
  • Espandiari P, Lehmler H, Stemm DN, Glauert HP, Robertson LW. 2003. PCB metabolites as initiating agents in hepatocarcinogenesis. In: Proceedings of the 42nd Annual Meeting of the Society of Toxicology (SOT), March 9-13, 2003. Salt Lake City, UT.
  • Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M. 2003. PCB 104 increases permeability of human microvascular endothelial cells: involvement of matrix metalloproteinases. FASEB J 17(5):A1082-A1082Part2Suppl.S.
  • Fadhel ZA, Bunaciu RP, Glauert HP, Robertson LW, Ludewig G. 2003. Lipid peroxidation and antioxidant enzymes in testes of rats treated with 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and effects of corn oil, medium-chain triglyceride (MCT) oil and olive oil. In: Proceedings of the 42nd Annual Meeting of the Society of Toxicology (SOT), March 9-13, 2003. Salt Lake City, UT.
  • Fadhel ZA, Bunaciu RP, Glauert HP, Robertson LW, Ludewig G. 2003. Lipid peroxidation and antioxidant enzymes in testes of rats treated with 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and effects of corn oil, medium-chain triglyceride (MCT) oil and olive oil. Toxicol Sci 72(1):1771Suppl.S.
  • Harp C, Stafine N, Bunaciu RP, Lu Z, Tharappel JC, Robertson LW, Spear BT, Glauert HP. 2003. Influence of purified diets on the induction of cell proliferation by the hepatic tumor promoters 2,2',4,4'5,5'-hexachlorobiphenyl (PCB-153) and the peroxisome proliferator ciprofibrate. FASEB J 17(5):A1155Suppl.S.
  • Hennig B, Toborek M, Robertson LW. 2003. Nutrition and proinflammatory mechanisms of PCB toxicity in the vascular endothelium. Fresenius Environmental Bulletin 12(2):240-244.
  • Kania-Korwel I, Lehmler H, Robertson LW, Parkin S. 2003. 2,4,5-trichloro-1-iodobenzene. Acta Crystallogr B E59(Part7):o1048-o1049.
  • Kania-Korwel I, Robertson LW, Lehmler H, Parkin S. 2003. 2,4,6-Trichloroiodobenzene. Acta Crystallogr B E59(Part1):o1770-o1771.
  • Lee YW, Park HJ, Son KW, Hennig B, Robertson LW, Toborek M. 2003. 2,2',4,6,6'-Pentachlorobiphenyl (PCB104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicol Appl Pharmacol 189(1):1-10. PMID:12758055
  • Lehmler H, Price DJ, Garrison AW, Birge WJ, Robertson LW. 2003. Distribution of PCB 84 atropisomers in female C57BL/6 mice. Presented at the 42nd Annual Meeting of the Society of Toxicology in Salt Lake City, Utah, March 9-13, 2003. In: Proceedings of the 42nd Annual Meeting of the Society of Toxicology (SOT), March 9-13, 2003. Salt Lake City, UT.
  • Lehmler H, Price DJ, Garrison AW, Birge WJ, Robertson LW. 2003. Distribution of PCB 84 Enantiomers in C57BL/6 Mice. Fresenius Environmental Bulletin 12(2):254-260.
  • Lu Z, Robertson LW, Spear BT, Glauert HP. 2003. Effect of 2,2', 4,4', 5,5' -hexachlorobiphenyl (PCB153) on gene expression in mice deficient in the P50 subunit of NF-kappa B. In: Proceedings of the 42nd Annual Meeting of the Society of Toxicology (SOT), March 9-13, 2003. Salt Lake City, UT.
  • Lu Z, Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. 2003. Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA binding activity of NF-kappaB and AP-1 in rats. Mol Carcinog 37(4):171-180. doi:10.1002/mc.10135 PMID:12891626
  • Ludewig G, Tampal N, Robertson LW. 2003. Comparative study of PCB, Pbb and PBDE mixtures on serum parameters in the rat. Presented at the 42nd Annual Meeting of the Cociety of Toxicology in Salt Lake City, Utan, March 9-13, 2003. In: Proceedings of the 42nd Annual Meeting of the Society of Toxicology (SOT), March 9-13, 2003. Salt Lake City, UT.
  • Ramadass P, Meerarani P, Toborek M, Robertson LW, Hennig B. 2003. Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells. Toxicol Sci 76(1):212-219. PMID:12970578
  • Ramadass P, Robertson LW, Toborek M, Meerarani P, Hennig B. 2003. Dietary phenolics modulate PCB-induced endothelial toxicity. FASEB J 17:A1361.
  • Sulkowski WW, Kania-Korwel I, Robertson LW. 2003. Polychlorinated biphenyls production in Poland. Fresenius Environmental Bulletin 12:152-157.
  • Sulkowski WW, Kania-Korwel I, Robertson LW, Szafran B, Lulek J. 2003. Post-production polychlorinated biphenyls levels in soil. Fresenius Environmental Bulletin 12:158-164.
  • Tampal N, Myers S, Robertson LW. 2003. Binding of polychlorinated biphenyls/metabolites to hemoglobin. Toxicol Lett 142(1-2):53-60. PMID:12765239
  • Tampal N, Robertson LW, Srinivasan C, Ludewig G. 2003. Polychlorinated biphenyls are not substrates for the multidrug resistance transporter-1. Toxicol Appl Pharmacol 187(3):168-177. PMID:12662900
  • Wlodarczyk-Makula M, Sulkowski WW, Popenda A, Robertson LW. 2003. The influence of sewage and sludge treatment processes on concentrations of polycyclic aromatic hydrocarbons. Fresenius Environmental Bulletin 12:338-342.

2002

  • Choi W, Lee YW, Hennig B, Robertson LW, Toborek M. 2002. PCB-induced inflammatory reactions in human endothelial cells: implication in cancer metastasis. FASEB J 16:A961.
  • Espandiari P, Glauert HP, Robertson LW. 2002. Replacement of partial hepatectomy with fasting/refeeding or the use of neonatal animals in the resistant hepatocyte model. Toxicol Sci 66:310.
  • Fadhel ZA, Lu Z, Robertson LW, Glauert HP. 2002. Effect of 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats. Toxicology 175(1-3):15-25. PMID:12049832
  • Fadhel ZA, Stafine N, Glauert HP, Robertson LW, Ludewig G. 2002. The effects of purified vs. unrefined diets on lipid peroxidation and antioxidant enzymes in tests of PCB-153 treated rats. Toxicol Sci 66:349.
  • Hansen LA, Machala M, James MO, Hennig B, Glauert HP, Narbonne J, van Bree L, Schultz T, Grevatt P, Suk WA, Holoubek I, Robertson LW. 2002. Research needs identified. In: Proceedings of the 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs (polychlorinated biphenyls), 2002. Brno, Czech Republic.
  • Hansen LG, Machala M, Fischer L, James MO, Hennig B, Glauert HP, Narbonne J, van Bree L, Schultz T, Grevett P, Suk WA, Holoubek I, Robertson LW. 2002. Research needs identified at the second PCB Workshop in Brno, Czech Republic. Toxicol Sci 87(3):261-265. doi:10.1080/02772240500079011
  • Hennig B, Hammock BD, Slim RM, Toborek M, Viswanathan S, Robertson LW. 2002. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. Int J Hyg Environ Health 205(1-2):95-102. PMID:12018021
  • Hennig B, Meerarani P, Slim RM, Toborek M, Daugherty A, Silverstone AE, Robertson LW. 2002. Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicol Appl Pharmacol 181(3):174-183. PMID:12079426
  • Hennig B, Meerarani P, Toborek M, Daugherty A, Silverstone AE, Robertson LW. 2002. Proinflammatory properties of coplanar PCBs. Organohalogen Compounds 55:355-358.
  • Hennig B, Toborek M, Robertson LW. 2002. Nutrition and proinflammatory mechanisms of PCB toxicity in the vascular endothelium. In: Proceedings of the 2nd International PCB (Polychlorinated Biphenyls) workshop. Brno, Czech Republic.
  • James MO, van den Hurk P, Kubiczak GA, Robertson LW, Lehmler H. 2002. Hydroxylated PCBs that are poor substrates but good inhibitors of UDP-glucuronosyltransferase in the channel catfish. FASEB J 16:A573.
  • James MO, Wang L, Faux LR, Lehmler H, Robertson LW. 2002. Hydroxylated PCB as inhibitors of the glucuronidation and sulfonation of hydroxylated benzo(a)pyrene metabolites. In: Proceedings of the 2nd International PCB (Polychlorinated Biphenyls) workshop. Brno, Czech Republic.
  • Lehmler H, Parkin S, Robertson LW. 2002. The three-dimensional structure of 3,3 ',5 '-trichloro-4-methoxybiphenyl, a "coplanar" polychlorinated biphenyl (PCB) derivative. Chemosphere 46(3):485-488. PMID:11829405
  • Lehmler H, Robertson LW, Parkin S. 2002. 2-(3,5-Dichlorophenyl)-1,4-benzoquinone. Acta Crystallogr B E58:o366-o367.
  • Lehmler H, Robertson LW, Parkin S, Brock CP. 2002. Z'=4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds. Acta Crystallogr B 58(Pt1):140-147. PMID:11818662
  • Lu Z, Robertson LW, Spear BT, Glauert HP. 2002. Effect of 2,2', 4,4', 5,5' -hexachlorobiphenyl (PCB153) on gene expression in mice deficient in the P50 subunit of NF-kappa B. In: Proceedings of the Superfund Basic Research Program Annual Meeting, November 3-6, 2002. Tucson, AZ.
  • Machala M, Blaha L, Pliskova M, Vondracek J, Lehmler H, Malmberg T, Robertson LW. 2002. Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines. Organohalogen Compounds 56:25-28.
  • Pereg D, Robertson LW, Gupta RC. 2002. DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites. Chem Biol Interact 139(2):129-144. PMID:11823002
  • Srinivasan A, Robertson LW, Ludewig G. 2002. Sulfhydryl binding and topoisomerase inhibition by PCB Metabolites. Chem Res Toxicol 15(4):497-505. PMID:11952335
  • Tampal N, Lehmler H, Espandiari P, Malmberg T, Robertson LW. 2002. Glucuronidation of hydroxylated polychlorinated biphenyls (PCBs). Chem Res Toxicol 15(10):1259-1266. doi:10.1021/tx0200212 PMID:12387623
  • Tampal N, Robertson LW, Ludewig G. 2002. In vivo MDR1 transport studies with PCB 77. Organohalogen Compounds 55:457-459.
  • Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. 2002. Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by Polychlorinated Biphenyls. Toxicol Appl Pharmacol 179(3):172-184. PMID:11906247
  • Toborek M, Robertson LW, Hennig B. 2002. PCB-induced proinflammatory reactions and cell death of human endothelial cells: relationships to cander metastasis. In: Proceedings of the 2nd International PCB (Polychlorinated Biphenyls) workshop. Brno, Czech Republic.
  • Wang L, Lehmler H, Robertson LW, James MO. 2002. In vitro inhibition of sulfotransferase activity of 3-hydroxy-benzo(a)pyrene by hydroxylated PCBs. In: Proceedings of the 11th North American ISSX (International Study of Xenobiotics) Meeting, October 27-31. Orlando, FL.
  • Wang L, Lehmler H, Robertson LW, James MO. 2002. In vitro inhibition of sulfotransferase activity of 3-hydroxy-benzo(a)pyrene by hydroxylated PCBs. J Mol Biol Suppl34:195.

2001

  • Arif JM, Lehmler H, Robertson LW, Gupta RC. 2001. Covalent interaction of synthetic benzoquinones and hydroquinones of polychlorinated biphenyls with DMA. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.403-404.
  • Espandiari P, Glauert HP, Robertson LW. 2001. Replacement of partial hepatectomy with fasting/refeeding or the use of neonatal animals in the resistant hepatocyte model. In: Proceedings of the Superfund Basic Research Program Annual Meeting: Assessing Risks of Hormonally Active Agents, December 10-12, 2001. University of Florida Conference Center, Gainsville, FL.
  • Espandiari P, Twaroski TP, Festag M, Lee EY, Glauert HP, Robertson LW. 2001. Effect of 4-chlorobiphenyl as an initiator of rat liver carcinogenisis. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.399-401.
  • Espandiari P, Twaroski TP, Festag M, Lee EY, Glauert HP, Robertson LW. 2001. Effect of 4-chlorobiphenyl as initiator of rat liver carcinogenisis. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.399-402.
  • Festag M, Ludewig G, Srinivasan A, Robertson LW, Steinberg P. 2001. PCB-3, PCB-44 und verschiedene PCB Metabolite verursachen keine Einselstrangbruche in DNA in vitro und/oder in vivo. In: Proceedings of the German Society for Experimental and Clinical Pharmacology and Toxicology 42nd Spring Meeting. 13-15 March 2001. Mainz, Germany.
  • Festag M, Ludewig G, Srinivasan A, Robertson LW, Steinberg P. 2001. PCB-3, PCB-77 und verschiedene PCB Metabolite verursachen keine Einselstrangbruche in DNA in vitro und/oder in vivo. In: Proceedings of the 42nd Fruhjahrstagung of the German Society for Experimental and Clinical Pharmacology and Toxicology, March 13-15, 2001. Mainz, Germany.
  • Festag M, Srinivasan A, Robertson LW, Ludewig G. 2001. Studies of the Effects of PCB-3, PCB-77, and Benzo(a)pyrene on Blood in Mice in vivo. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY.
  • Glauert HP, Calfee-Mason K, Li Y, Lu Z, Nilakantan V, O'Brien ML, Tharappel JC, Lee EY, Robertson LW, Spear BT. 2001. Effect of dietary vitamin E on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl (PCB-77) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) in rats initiated with diethylnitrosamine. In: Proceedings of the 44th Annual Meeting of the Polish Chemical Society, September 9-13, 2001. Katowice, Poland.
  • Glauert HP, Calfee-Mason K, Li Y, Lu Z, Nilakantan V, O'Brien ML, Tharappel JC, Lee EY, Robertson LW, Spear BT. 2001. Role of oxidative stress in the promotion of hepatocarcinogenesis by environmental chemicals 44th Annual Meeting of the Polish Chemical Society in Katowice, Poland, September 9-13, 2001. Cent Eur J Public Health 105.
  • Glauert HP, Silberhorn EM, Robertson LW. 2001. PCBs and tumor promotion. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.355-371.
  • Hennig B, Slim RM, Toborek M, Hammock BD, Robertson LW. 2001. Cardiovascular disease: endothelial cells as a target for PCB toxicity. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.211-220.
  • Hennig B, Toborek M, Reiterer G, Majkova Z, Oesterling EG, Meerarani P, Robertson LW. 2001. Nutrition Modulates PCB Toxicity: Implications in Atherosclerosis. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY.
  • Lehmler H, Brock CP, Patrick B, Robertson LW. 2001. Synthesis of polychlorinated biphenyls (PCBs) and their metabolites using the Suzuki-Coupling. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY.
  • Lehmler H, Parkin S, Robertson LW. 2001. 2,3,4-Trichlorobiphenyl. Acta Crystallogr B E57Part2:o111-o112.
  • Lehmler H, Robertson LW. 2001. Atropisomers of PBCs. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.61-66.
  • Lehmler H, Robertson LW. 2001. Synthesis of hydroxylated PCB metabolites with the Suzuki-coupling. Chemosphere 45(8):1119-1127. PMID:11695625
  • Lehmler H, Robertson LW. 2001. Synthesis of polychlorinated biphenyls (PCBs) using the Suzuki-Coupling. Chemosphere 45(2):137-143. PMID:11572605
  • Lehmler H, Robertson LW, Parkin S. 2001. 4-Chloro-3',4'-dihydroxybiphenyl. Acta Crystallogr B E57Part7:o590-o591.
  • Lu Z, Lee EY, Robertson LW, Spear BT, Glauert HP. 2001. Effect of dietary vitamin E on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl (PCB-77) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) in rats initiated with diethylnitrosamine. In: Proceedings of the 40th Annual Meeting of the Society of Toxicology (SOT), March 25-29, 2001. San Franciso, CA.
  • Lu Z, Lee EY, Robertson LW, Spear BT, Glauert HP. 2001. Effect of dietary vitamin E on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl (PCB-77) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) in rats initiated with diethylnitrosamine. Toxicol Sci 60:161.
  • Lu Z, Spear BT, Lee EY, Robertson LW, Glauert HP. 2001. Activation of Rat Hepatic Transcription Factor NF-kB by PCBs. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.419-420.
  • Ludewig G, Srinivasan A, McLean MR, Twaroski TP, Robertson LW. 2001. Oxidative Stess: Mechanisms of toxicity of persistent organic polllutants. In: Proceedings of the 44th Annual Meeting of the Polish Chemical Society, September 9-13, 2001. Katowice, Poland.
  • Ludewig G, Srinivasan A, McLean MR, Twaroski TP, Robertson LW. 2001. Oxidative stress: mechanisms of toxicity of persistent organic pollutants. Cent Eur J Public Health 111.
  • Ludewig G, Srinivasan A, Robertson LW. 2001. Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion. Cent Eur J Public Health 8:15-17. PMID:10943438
  • Oakley GG, Roe AL, Blouin RA, Twaroski TP, Ganguly TC, Vore M, Lehmler H, Robertson LW. 2001. 2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity. Mol Carcinog 30(4):199-208. PMID:11346882
  • Pereg D, Tampal N, Espandiari P, Robertson LW. 2001. Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice. Chem Biol Interact 137(3):243-258. PMID:11566292
  • Pereg D, Tampal N, Robertson LW. 2001. Covalent Binding of Benzo[a]pyrene, 4-Chlorobiphenyl and 3,3',4,4'-Tetrachlorobiphenyl to hepatic nuclear macromolecules in female mice. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.381-386.
  • Slim RM, Hammock BD, Toborek M, Robertson LW. 2001. The role of methyl linoleic acid epoxide and diol metabolites in the synergistic toxicity of linoleic acid and PCBs to vascular endothelial cells. Toxicol Sci 60:13.
  • Slim RM, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau C, Watkins BA, Viswanathan S, Hennig B. 2001. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicol Appl Pharmacol 171(3):184-193. PMID:11243918
  • Slim RM, Toborek M, Robertson LW, Lehmler H, Hennig B. 2001. Cellular glutathione status modulates PCB-induced stress response and apoptosis in vascular endothelial cells. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.313-315.
  • Srinivasan A, Espandiari P, Festag M, Robertson LW, Ludewig G. 2001. Analysis of DNA Strand Break Induction by PCB Metabolites in HL-60 Cells. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.395-398.
  • Srinivasan A, Espandiari P, Robertson LW, Ludewig G. 2001. Intracellular oxidative stress produced by PCB metabolites. Environ Health Perspect 60(1):1127.
  • Srinivasan A, Lehmler H, Robertson LW, Ludewig G. 2001. Production of DNA strand breaks in vitro and Reactive Oxygen Species in vitro and in HL-60 cells by PCB Metabolites. Toxicol Sci 60(1):92-102. PMID:11222876
  • Srinivasan A, Robertson LW, Ludewig G. 2001. Mechanisms of Toxicity of PCB Metabolites: Sulfhydryl Binding and ROS Generation. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.387-390.
  • Tampal N, Myers S, Pereg D, Robertson LW. 2001. Interaction of 4-Chlorobiphenyl and 3,3',4,4'-Tetrachlorobiphenyl with hemoglobin. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.391-394.
  • Tampal N, Robertson LW, Lehmler H, Srinivasan C, Ludewig G. 2001. PCBs as Substrates for the MDR Transporter. Environ Health Perspect 60(1):1118.
  • Tampal N, Robertson LW, Lehmler H, Srinivasan C, Ludewig G. 2001. PCBs as Substrates for the MDR Transporter. In: Proceedings of the 40th Annual Meeting of the Society of Toxicology (SOT), March 25-29, 2001. San Franciso, CA.
  • Tharappel JC, Robertson LW, Lee EY, Spear BT, Glauert HP. 2001. Effect Of 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB-153) And 3,3',4,4'-Tetrachlorobiphenyl (PCB-77) On NF-kB And AP-1 Activation, Altered Hepatic Foci Formation, Cell Proliferation, And Apoptosis In Rats. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.417-418.
  • Twaroski TP, O'Brien ML, Larmonier N, Glauert HP, Robertson LW. 2001. Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E and oxidative stress in the rat liver. Toxicol Appl Pharmacol 171(2):85-93. PMID:11222084
  • Twaroski TP, O'Brien ML, Robertson LW. 2001. effects of PCB 77 (3,3'4,4'-tetrachlorobiphenyl) on glutathione peroxidase activity and regulatory mechanisms. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.317-320.
  • Twaroski TP, O'Brien ML, Robertson LW. 2001. Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes and selenium status: implications for oxidative stress. Biochem Pharmacol 62(3):273-281. PMID:11434900

2000

  • Fadhel ZA, Lu Z, Robertson LW, Glauert HP. 2000. Role of cytochrome P-450 induction and lipid peroxidation in 3,3',4,4'-tetrachlorobiphenyl (PCB-77)- and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153)-induced toxicity in liver of male rats. Toxicol Sci 54:78.
  • Fadhel ZA, Lu Z, Robertson LW, Glauert HP. 2000. Role of cytochrome P-450 induction and lipid peroxidation in 3,3',4,4'-tetrachlorobiphenyl (PCB-77)- and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153)-induced toxicity in liver of male rats. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology (SOT), March 19-23, 2000. Philadelphia, PA.
  • Glauert HP, Tharappel JC, Lee EY, Robertson LW, Spear BT. 2000. Effect of PCBs on the activation of the transcription factors AP-1 and NF-kB. Cent Eur J Public Health 8Suppl::17-18. PMID:10943439
  • Hennig B, Slim RM, Toborek M, Malecki A, Robertson LW. 2000. Effects of lipids and antioxidants on PCB-mediated dysfunction of vascular endothelial cells. Cent Eur J Public Health 8(supp):18-19. PMID:10943440
  • Hennig B, Slim RM, Toborek M, Watkins BA, Robertson LW. 2000. Modulation of PCB-induced endothelial activation by fatty acids and antioxidants. In: Proceedings of the 1st PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs (polychlorinated biphenyls), 2000. Lexington, KY.
  • Lu Z, Spear BT, Robertson LW, Glauert HP. 2000. Activation of hepatic hepatic NF-kB by polychlorinated biphenyls (PCBs) in vivo and in cultured rat hepatocytes. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology (SOT), March 19-23, 2000. Philadelphia, PA.
  • Lu Z, Spear BT, Robertson LW, Glauert HP. 2000. Activation of hepatic hepatic NF-kB by polychlorinated biphenyls (PCBs) in vivo and in cultured rat hepatocytes. Toxicol Sci 54:254.
  • Ludewig G, Espandiari P, Festag M, Lehmler H, Pereg D, Srinivasan A, Tampal N, Twaroski TP, Arif JM, Gupta RC, Robertson LW. 2000. Mechanisms of cancer induction by polychlorinated biphenyls (PCBs). In: Proceedings of the 2nd Department of Defense Breast Cancer Research Program, 2000. Alanta, GA. pp.325.
  • Ludewig G, Espandiari P, Festag M, Lehmler H, Pereg D, Srinivasan A, Tampal N, Twaroski TP, Arif JM, Gupta RC, Robertson LW. 2000. Mechanisms of cancer induction by polychlorinated biphenyls (PCBs). In: Proceedings of the "Era of Hope" Department of Defense Breast Cancer Research Program Meeting, June 8-11, 2000. Atlanta, GA.
  • Ludewig G, Lehmler H, Boivin R, Srinivasan A, Robertson LW. 2000. Reactivity of halogenated and non-halogenated dihydroxy-biphenyls in vitro and in cells in culture. Toxicol Sci 54(1):76.
  • Ludewig G, Lehmler H, Boivin R, Srinivasan A, Robertson LW. 2000. Reactivity of halogenated and non-halogenated dihydroxy-biphenyls in vitro and in cells in culture. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology (SOT), March 19-23, 2000. Philadelphia, PA.
  • McLean MR, Twaroski TP, Robertson LW. 2000. Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)- 1, 4-benzoquinones, oxidation products of polychlorinated biphenyls. Arch Biochem Biophys 376(2):449-455. doi:10.1006/abbi.2000.1754 PMID:10775433
  • Pereg D, Tampal N, Robertson LW. 2000. Covalent binding of benzo[a]pyrene, 4-chlorobiphenyl and 3,3',4,4'-tetrachlorobiphenyl to nuclear macromolecules in female mice. Toxicol Sci 54(1):366.
  • Robertson LW, Espandiari P, Lehmler H, Pereg D, Srinivasan A, Tampal N, Twaroski TP, Ludewig G, Glauert HP, Arif JM, Gupta RC. 2000. Metabolism and activation of polychlorinated biphenyls (PCBs). Cent Eur J Public Health 8Suppl:14-15. PMID:10943437
  • Robertson LW, Gupta RC. 2000. Chapter 2: Metabolism of polychlorinated biphenyls (PCBs) generates electrophiles and reactive oxygen species that damage DNA. In: Molecular Drug Metabolism and Toxicology. OICA International Limited, London, United Kingdom. pp.16-32.
  • Slim RM, Toborek M, Robertson LW, Lehmler H, Hennig B. 2000. Cellular glutathione status modulates PCB-induced stress response and apoptosis in porcine endothelial cells. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology (SOT), March 19-23, 2000. Philadelphia, PA.
  • Slim RM, Toborek M, Robertson LW, Lehmler H, Hennig B. 2000. Cellular glutathione status modulates Polychlorinated Biphenyl-induced stress response and apoptosis in vascular endothelial cells. Toxicol Appl Pharmacol 166(1):36-42. PMID:10873716
  • Slim RM, Toborek M, Robertson LW, Lehmler H, Hennig B. 2000. PCB-induced stress response and apoptosis in vascular endothelial cells. In: Proceedings of the 1st PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs (polychlorinated biphenyls), 2000. Lexington, KY.
  • Srinivasan A, Robertson LW, Ludewig G. 2000. PCB metabolites: cytotoxicity, glutathione depletion and inhibition of topoisomerase II. In: Proceedings of the 39th Annual Meeting of the Society of Toxicology (SOT), March 19-23, 2000. Philadelphia, PA.
  • Srinivasan A, Robertson LW, Ludewig G. 2000. PCB metabolites: cytotoxicity, glutathione depletion and inhibition of topoisomerase II. Toxicol Sci 54(1):78.
  • Tampal N, Myers S, Pereg D, Robertson LW. 2000. Hemoglobin adducts of polychlorinated biphenyls as potential biomarkers of exposure. Toxicol Sci 54(1):365.
  • Tharappel JC, Robertson LW, Lee EY, Spear BT, Glauert HP. 2000. Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and 3,3',4,4'-tetrachlorobiphenyl (PCB-77) on NF-kB and AP-1 activation, altered hepatic foci formation, cell proliferation, and apoptosis in rats. Toxicol Sci 54:271.
  • Toborek M, Lee YW, Robertson LW, Zimmer S, Hennig B. 2000. PCB can induce overexpression of ICAM-1 in human endothelial cells. In: Proceedings of the 1st PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs (polychlorinated biphenyls), 2000. Lexington, KY.
  • Twaroski TP, Larmonier N, O'Brien ML, Glauert HP, Robertson LW. 2000. PCB-induced effects on cytochrome P-450 1A1, DT-diaphorase, AP-1 binding and oxidative stress in the rat liver. Chapter 41in: Proceedings of the 91st Annual Meeting of American Association for Cancer Research Annual Meeting, 2000. San Diego, CA. pp.507.

1999

  • Arif JM, Robertson LW, Gupta RC. 1999. Artificial production of 8-oxodeoxyguanosine (8-oxodG) during tissue DNA processing and its inhibition. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.4251.
  • Espandiari P, Robertson LW, Ludewig G. 1999. Dihydroxybiphenyls: A structure-activity comparison. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.328.
  • Espandiari P, Srinivasan A, Robertson LW, Ludewig G. 1999. Structure activity relationships for strand break induction and toxicity of lower halogenated dihydroxy-biphenyls. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.2259.
  • Hennig B, Slim RM, Toborek M, Robertson LW. 1999. Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells. J Biochem Mol Toxicol 13(2):83-91. PMID:9890193
  • Lu Z, Spear BT, Lee EY, Robertson LW, Glauert HP. 1999. Activation of hepatic NF-ÇB by a single dose of Polychlorinated Biphenyls (PCBs). FASEB J 13:681.10.
  • Slim RM, Toborek M, Malecki A, Robertson LW, Hennig B. 1999. Protective role of vitamin E on PCB-induced dysfunction of vascular endothelial cells. FASEB J 13:651.17.
  • Srinivasan A, Espandiari P, Robertson LW, Ludewig G. 1999. DNA strand break induction by the PCB metabolite 4-chloro-2',5'-dihydroxybiphenyl. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.2258.
  • Srinivasan A, Lehmler H, Shaw JR, Robertson LW, Ludewig G. 1999. Superoxide production and glutathione binding by hydroquinone and p-quinone metabolites of Polychlorinated Biphenyls (PCBs). In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.4261.
  • Tharappel JC, Robertson LW, Lee EY, Spear BT, Glauert HP. 1999. Effect of the PCBs 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and 3,3',4,4'-tetrachlorobiphenyl (PCB-77) on cell proliferation and the activation of the transcription factors NF-ÇB and AP-1 in rats treated with diethylnitrosamine (DEN). FASEB J 13:162.3.
  • Twaroski TP, Arif JM, Gupta RC, Robertson LW. 1999. Antioxidant enzyme levels and oxidative damage in rats exposed to selected Polychlorinated Biphenyls (PCBs) after maximal cytochrome P450 induction. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.4269.
  • Twaroski TP, Espandiari P, Robertson LW. 1999. Effects of selected PCB congeners on drug- and glutathione-metabolizing enzymes in the rat. Toxicol Sci 48(1-S):

1998

  • Bachas LG, Daunert S, Robertson LW. 1998. Information dissemination and outreach activities at the University of Kentucky. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA. pp.69.
  • de Boer J, Robertson LW, Dettmer F, Wichmann H, Bahadir M. 1998. Polybrominated diphenyl- ethers in human adipose tissue and relation with watching television - a case study. Organohalogen Compounds 35:407-410.
  • Espandiari P, Ludewig G, Glauert HP, Robertson LW. 1998. Activation of hepatic NF-ÇB by the herbicide Dicamba (2-methoxy-3,6-dichlorobenzoic acid) in female and male rats. J Biochem Mol Toxicol 12:339-344. PMID:9736482
  • Glauert HP, Li Y, Nilakantan V, Tharappel JC, Calfee KG, Lu Z, Robertson LW, Spear BT. 1998. Role of NF-ÇB in the promotion of hepatocarcinogenesis. Pol J Pharmacol 50:80-81.
  • Glauert HP, Lu Z, Al-bayati Z, Lee EY, Robertson LW. 1998. Effects of PCBs on hepatic lipid peroxidation and transcription factor activation in rats. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA. pp.9.
  • Hennig B, Slim RM, Toborek M, Robertson LW. 1998. Polychlorinated biphenyls (PCBs) and cardiovascular disease. Pol J Pharmacol 50:81-82.
  • Ludewig G, Espandiari P, Srinivasan A, Robertson LW. 1998. Reactive oxygen species (ROS) and genotoxicity associated with PCB metabolism. Pol J Pharmacol 50(83):
  • Ludewig G, Srinivasan A, Espandiari P, Robertson LW. 1998. Generation of reactive oxygen species (ROS) and genotoxicity by metabolites of polychlorinated biphenyls (PCBs). Organohalogen Compounds 37:143-146.
  • McLean MR, Twaroski TP, Robertson LW. 1998. A new mechanism of toxicity for polychlorinated biphenyls (PCBs): Redox cycling and superoxide generation. Organohalogen Compounds 37:59-62.
  • Oakley GG, Roe AL, Blouin RA, Ganguly TC, Vore M, Robertson LW. 1998. Activation of AP-1 and STAT transcription factors by non-coplanar Polychlorinated Biphenyls (PCBs). Toxicol Sci 42:133.
  • Robertson LW, Amaro AR, Bauer U, Lehmler H, Shaw JR, McLean MR, Twaroski TP, Oakley GG, Arif JM, Gupta RC. 1998. A new mechanism of toxicity for Polychlorinated Biphenyls (PCBs). Pol J Pharmacol 50(84):
  • Slim RM, Toborek M, Robertson LW, Hennig B. 1998. Linoleic acid amplifies PCB-mediated dysfunction of endothelial cells. FASEB J 12(5):A1008.
  • Toborek M, Slim RM, Robertson LW, Hennig B. 1998. Linoleic acid amplifies PCB-mediated dysfunction of endothelial cells. In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA. pp.11.
  • Twaroski TP, Robertson LW. 1998. PCB-induced oxidative stress and effects on glutathione, glutathione peroxidase and catalase. Toxicol Sci 42:153.

1997

  • Arcaro KF, Gierthy JF, Yang Y, Robertson LW, Oakley GG, Vakharia D. 1997. Position of hydroxyl group influences PCB estrogenicity and antiestrogenicity. Organohalogen Compounds 34:386-390.
  • Gierthy JF, Yang Y, Robertson LW, Oakley GG, Arcaro KF, Vakharia D. 1997. Position of hydroxyl group influences PCB estrogenicity and antiestrogenicity. Environ Health Perspect 36(1):159.
  • McLean MR, Twaroski TP, Robertson LW. 1997. Redox-cycling of catechol and hydroquinone metabolites of polychlorinated biphenyls (PCBs). Fundam Appl Toxicol 36:159.
  • Robertson LW, Amaro AR, Bauer U, Espandiari P, Ludewig G, McLean MR, Oakley GG, Twaroski TP, Gupta RC. 1997. Oxidative DNA Damage Induced by Polychlorinated Biphenyls (PCBs). New Activation Mechanisms. In: Proceedings of the DOD (Department of Defense ) Breast Cancer Research Program Meeting. Washington, DC. pp.211.

1996

  • Amaro AR, Oakley GG, Bauer U, Spielmann HP, Robertson LW. 1996. Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase. Chem Res Toxicol 9:623-629. PMID:8728508
  • Ludewig G, Oakley GG, Espandiari P, Robertson LW. 1996. Production of superoxide and DNA strand breaks by diol metabolites of lower chlorinated biphenyls (PCBs). In: Proceedings of the Eighty Seventh Annual Meeting of the (AACR) American Association of Cancer Research, 1996. pp.989.
  • McLean MR, Bauer U, Amaro AR, Robertson LW. 1996. Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl. Chem Res Toxicol 9:158-164. PMID:8924585
  • McLean MR, Robertson LW, Gupta RC. 1996. Detection of PCB-adducts by the 32P- postlabeling technique. Chem Res Toxicol 9:165-171. PMID:8924587
  • Oakley GG, Devanaboyina U, Robertson LW, Gupta RC. 1996. Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs). In: Proceedings of the Eighty Seventh Annual Meeting of the (AACR) American Association of Cancer Research, 1996. pp.996.
  • Oakley GG, Devanaboyina U, Robertson LW, Gupta RC. 1996. Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): Implications for PCB induced oxidative stress in breast cancer. Chem Res Toxicol 9:1285-1292. PMID:8951230
  • Oakley GG, Robertson LW, Gupta RC. 1996. Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling. Carcinogenesis 17:109-114. PMID:8565118
  • Silberhorn EM, Birge WJ, Robertson LW. 1996. SARs and mechanisms of action for PCB congeners: Fathead minnow developmental toxicity. In: Society of Environmental Toxicology and Chemistry (SETAC) Annual Meeting 1996. Washington, DC. pp.P0936.

1995

  • Bauer U, Amaro AR, Robertson LW. 1995. A new strategy for the synthesis of polychlorinated biphenyl metabolites. Chem Res Toxicol 8:92-95. PMID:7703372
  • Berberian I, Chen L, Robinson FR, Glauert HP, Chow CK, Robertson LW. 1995. Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl in rats initiated with diethylnitrosamine. Carcinogenesis 16(2):393-398. PMID:7859372
  • Espandiari P, Thomas VA, Glauert HP, O'Brien ML, Noonan D, Robertson LW. 1995. The herbicide Dicamba (2-methoxy-3,6-dichlorobenzoic acid) is a peroxisome proliferator in rats. Fundam Appl Toxicol 26(1):85-90. PMID:7657066
  • Hennig B, Toborek M, Mattson MP, Gupta RC, Barger SW, Connell P, Robertson LW. 1995. Environmental chemical-mediated endothelial cell dysfunction: Implications in atherosclerosis. FASEB J 9:A323.
  • Toborek M, Barger SW, Mattson MP, Espandiari P, Robertson LW, Hennig B. 1995. Exposure to polychlorinated biphenyls causes endothelial cell dysfunction. J Biochem Toxicol 10(4):219-226. doi:10.1002/jbt.2570100406 PMID:8568836
  • Wilson MW, Lay LT, Chow CK, Tai H, Robertson LW, Glauert HP. 1995. Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid. Arch Toxicol 69(7):491-497. PMID:8526745
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