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Your Environment. Your Health.

Person Details: Donald C. Malins

Superfund Research Program

Donald C. Malins

Pacific NW Research Institute
Biochemical Oncology Program
Seattle, Washington 98122
Phone: 206-726-1240
Fax: 206-726-1235
Email: dmalins@pnri.org

Projects

Research Briefs

Hazardous Waste Sites

Harbor Island

  • University of Washington: Effects Related Biomarkers of Toxic Exposures
  • University of Washington: Environmental Stress Indicators for Fish at Superfund Sites: GC-MS and FT-IR Markers of Contaminant-Induced Damage to Gill Tissue

Harbor Island (Lead)

  • University of Washington: Environmental Stress Indicators for Fish at Superfund Sites: GC-MS and FT-IR Markers of Contaminant-Induced Damage to Gill Tissue

San Francisco Bay

  • University of Washington: Environmental Stress Indicators for Fish at Superfund Sites: GC-MS and FT-IR Markers of Contaminant-Induced Damage to Gill Tissue

Publications

2006

  • Malins DC, Anderson KM, Stegeman JJ, Jaruga P, Green VM, Gilman NK, Dizdaroglu M. 2006. Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound. Environ Health Perspect 114(6):823-829. PMID:16759979

2005

  • Malins DC, Stegeman JJ, Green VM, Gilman NK, Anderson KM. 2005. Spectral Models for Assessing Exposure of Fish to Contaminants. In: Techniques in Aquatic Toxicology. CRC Press, Inc., Boca Raton, FL. pp.537-545.

2004

  • Malins DC, Stegeman JJ, Anderson JW, Johnson PM, Gold J, Anderson KM. 2004. Structural changes in gill DNA reveal the effects of contaminants on Puget Sound fish. Environ Health Perspect 112(5):511-515. PMID:15064153

2000

  • Malins DC, Polissar NL, Ostrander GK, Vinson MA. 2000. Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand. Proc Natl Acad Sci U S A 97(23):12442-12445. PMID:11058168

1998

  • Malins DC, Polissar NL, Schaefer S, Su Y, Vinson MA. 1998. A unified theory of carcinogenesis based on order-disorder transitions in DNA structure as studied in the human ovary and breast. Proc Natl Acad Sci U S A 95(13):7637-7642. PMID:9636202

1997

  • Malins DC, Polissar NL, Gunselman SJ. 1997. Infrared spectral models demonstrate that exposure to environmental chemicals leads to new forms of DNA. Proc Natl Acad Sci U S A 94(8):3611-3615. PMID:9108025
  • Malins DC, Polissar NL, Su Y, Gardner HS, Gunselman SJ. 1997. A new structural analysis of DNA using statistical models of infrared spectra. Nat Med 3(8):927-930. PMID:9256288

1996

  • Malins DC, Polissar NL, Garner MM, Gunselman SJ. 1996. Mutagenic DNA base modifications are correlated with lesions in nonneoplastic hepatic tissue of the English sole carcinogenesis model. Cancer Res 56(24):5563-5565. PMID:8971153
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