Superfund Research Program
Research Translation Core
The Research Translation Core (RTC) worked with investigators and trainees to translate and improve the relevance of research, through partnerships with collaborators including government agencies and others, facilitation of technology transfer, engagement with business and industry, and communication to a broad audience using a variety of tools. The RTC continued to expand the Key Characteristics (KCs) approach to hazard identification and published a paper on biomarkers and assays of use in evaluating potential carcinogens (Smith 2020) resulting from meetings held in 2018 and 2019. The Core convened expert groups and led biweekly meetings to develop KCs of cardiovascular toxicants and immunotoxicants. The RTC paper on the KCs of neurotoxicants is close to submission. The Core launched a website to share KC resources with researchers and regulators and began preparing tables of assays and biomarkers for carcinogens. Investigators have actively engaged in research translation efforts in a variety of ways during this research period including assessment of Superfund chemicals and developing and promoting approaches and research strategies to improve toxicity testing and hazard assessment. The RTC have been proactive in sharing these efforts through NIEHS and the Center’s own web and social media outlets.