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Your Environment. Your Health.

Project Publications: University of California-Berkeley: Exposomics of Endocrine Disruption

Superfund Research Program

Exposomics of Endocrine Disruption

Project Leader: Martyn T. Smith
Co-Investigator: Jen-Chywan Wang
Grant Number: P42ES004705
Funding Period: 2017-2022
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

Learn More About the Grantee

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Publications

2020

  • Castriota F, Rieswijk L, Dahlberg S, La Merrill MA, Steinmaus CM, Smith MT, Wang J. 2020. A state-of-the-science review of arsenics effects on glucose homeostasis in experimental models. Environ Health Perspect 128(1):doi:10.1289/EHP4517 PMID:31898917 PMCID:PMC7015542
  • Castriota F, Zushin PH, Sanchez SS, Phillips RV, Hubbard AE, Stahl A, Smith MT, Wang J, La Merrill MA. 2020. Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice. Am J Physiol Endocrinol Metab 318:E667-E677. doi:10.1152/ajpendo.00282.2019 PMID:32045263
  • La Merrill MA, Vandenberg LN, Smith MT, Goodson III WH, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller RT. 2020. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinol 16:45-57. doi:10.1038/s41574-019-0273-8 PMID:31719706 PMCID:PMC6902641

2019

  • Ahearn A. 2019. Key characteristics: a new approach to identifying potential toxicants, with Martyn Smith. The Researcher's Perspective 2019(1):doi:10.1289/EHP5776
  • Arzuaga X, Smith MT, Gibbons CF, Skakkelmek NE, Yost EE, Beverly BE, Hotchkiss AK, Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS. 2019. Proposed key characteristics of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health hazard assessments. Environ Health Perspect 127(6):65001. doi:10.1289/ehp5045 PMID:31199676 PMCID:PMC6792367
  • Chen T, Lee RA, Tsai SL, Kanamaluru D, Gray NE, Yiv N, Cheang R, Tan JH, Lee JY, Fitch MD, Hellerstein MK, Wang J. 2019. An ANGPTL4 ceramide protein kinase C axis mediates chronic glucocorticoid exposure induced hepatic steatosis and hypertriglyceridemia in mice. J Biol Chem 294(23):9213-9224. doi:10.1074/jbc.RA118.006259 PMID:31053639 PMCID:PMC6556567
  • Eick SM, Ferreccio Readi C, Acevedo J, Castriota F, Cordero JF, Roh T, Smith AH, Smith MT, Steinmaus CM. 2019. Socioeconomic status and the association between arsenic exposure and type 2 diabetes. Environ Res 172:578-585. doi:10.1016/j.envres.2019.03.013 PMID:30875511 PMCID:PMC7003534
  • La Merrill MA, Johnson CL, Smith MT, Kandula NR, Macherone A, Pennell KD, Kanaya AM. 2019. Exposure to persistent organic pollutants (POPs) and their relationship to hepatic fat and insulin insensitivity among Asian Indian immigrants in the United States. Environ Sci Technol 53:13906-13918. doi:10.1021/acs.est.9b03373 PMID:31746186
  • Lee KM, Bassig BA, Zhang L, Vermeulen R, Hu W, Wong JJ, Wen C, Huang Y, Purdue MP, Ji B, Li L, Tang X, Rothman N, Smith MT, Lan Q. 2019. Association between occupational exposure to trichloroethylene and serum levels of microRNAs: a cross-sectional molecular epidemiology study in China. Int Arch Occup Environ Health 92(8):1077-1085. doi:10.1007/s00420-019-01448-x PMID:31161417 PMCID:PMC6953905
  • Lee KM, Zhang L, Vermeulen R, Hu W, Bassig BA, Wong JJ, Qiu C, Purdue MP, Wen C, Walker DI, Jones DP, Li L, Huang Y, Rothman N, Smith MT, Lan Q. 2019. Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards. Occup Environ Med 76(6):376-381. doi:10.1136/oemed-2018-105583 PMID:30971425 PMCID:PMC6953904
  • Phillips RV, Rieswijk L, Hubbard AE, Vermeulen R, Zhang J, Hu W, Li L, Bassig BA, Wong JJ, Reiss B, Huang Y, Wen C, Purdue MP, Tang X, Smith MT, Rothman N, Lan Q. 2019. Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer. Epigenetics 14(11):1112-1124. doi:10.1080/15592294.2019.1633866 PMID:31241004 PMCID:PMC6773405

2018

  • Daniels SI, Chambers JC, Sanchez SS, La Merrill MA, Hubbard AE, Macherone A, McMullin M, Zhang L, Elliott P, Smith MT, Kooner JS. 2018. Elevated levels of organochlorine pesticides in South Asian immigrants are associated with an increased risk of diabetes. J Endocr Soc 2(8):832-841. doi:10.1210/js.2017-00480 PMID:30019022 PMCID:PMC6041775
  • Grigoryan H, Edmands WM, Lan Q, Carlsson H, Vermeulen R, Zhang L, Yin S, Li G, Smith MT, Rothman N, Rappaport SM. 2018. Adductomic signatures of benzene exposure provide insights into cancer induction. Carcinogenesis 39:661-668. doi:10.1093/carcin/bgy042 PMID:29538615 PMCID:PMC5932554
  • Guyton KZ, Rieswijk L, Wang A, Chiu WA, Smith MT. 2018. Key characteristics approach to carcinogenic hazard identification. Chem Res Toxicol 31(12):1290-1292. doi:10.1021/acs.chemrestox.8b00321 PMID:30521319 PMCID:PMC6424613
  • Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 39(4):614-622. doi:10.1093/carcin/bgy031 PMID:29562322 PMCID:PMC5888955
  • Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Re: Application of the key characteristics of carcinogens in cancer hazard evaluation : response to Goodman, Lynch and Rhomberg. Carcinogenesis 39(8):1091-1093. doi:10.1093/carcin/bgy082 PMID:29982359 PMCID:PMC6067125
  • McHale CM, Osborne G, Morello-Frosch R, Salmon AG, Sandy MS, Solomon G, Zhang L, Smith MT, Zeise L. 2018. Assessing health risks from multiple environmental stressors: moving from G x E to I x E. Mutat Res Rev Mutat Res 775:11-20. doi:10.1016/j.mrrev.2017.11.003 PMID:29555026 PMCID:PMC5863617
  • Rothman N, Zhang L, Smith MT, Vermeulen R, Lan Q. 2018. Formaldehyde, hematotoxicity, and chromosomal changes-response. Cancer Epidemiol Biomarkers Prev 27:120-121. doi:10.1158/1055-9965.epi-17-0804 PMID:29311167
  • Tachachartvanich P, Sangsuwan R, Ruiz HS, Sanchez SS, Durkin KA, Zhang L, Smith MT. 2018. Assessment of the endocrine-disrupting effects of trichloroethylene and its metabolites using in vitro and in silico approaches. Environ Sci Technol 52(3):1542-1550. doi:10.1021/acs.est.7b04832 PMID:29294279 PMCID:PMC6290898

2017

  • De La Rosa VY, Asfaha J, Fasullo M, Loguinov AV, Li P, Moore LE, Rothman N, Nakamura J, Swenberg JA, Scelo G, Zhang L, Smith MT, Vulpe CD. 2017. Editor's highlight: High-throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes. Toxicol Sci 160:111-120. doi:10.1093/toxsci/kfx159 PMID:28973557 PMCID:PMC5837773
  • Rothman N, Lan Q, Smith MT, Vermeulen R, Zhang L. 2017. Response to letter to the editor of Carcinogenesis by Pira et al., 2017. Carcinogenesis 38:1253-1255. doi:10.1093/carcin/bgx111 PMID:29040449
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