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Your Environment. Your Health.

Project Publications: University of Albany - SUNY: Studies on the Mechanisms Responsible for the Cognitive Impairment Caused by Exposure to PCBs

Superfund Research Program

Studies on the Mechanisms Responsible for the Cognitive Impairment Caused by Exposure to PCBs

Project Leader: David O. Carpenter
Grant Number: P42ES004913
Funding Period: 1995 - 2000

Project-Specific Links



  • Sasaki N, Jones LE, Morse G, Carpenter DO. 2023. Mixture effects of polychlorinated biphenyls (PCBs) and three organochlorine pesticides on cognitive function in mohawk adults at akwesasne. Int J Environ Res Public Health 20(2):1148. doi:10.3390/ijerph20021148 PMID:36673903 PMCID:PMC9859591


  • Aminov Z, Carpenter DO. 2020. Serum concentrations of persistent organic pollutants and the metabolic syndrome in Akwesasne Mohawks, a Native American community. Environ Pollut 260:8. doi:10.1016/j.envpol.2020.114004 PMID:32004963


  • Negoita S, Swamp L, Kelley B, Carpenter DO. 2001. Chronic diseases surveillance of St Regis Mohawk Health Service patients. J Public Health Manag Pract 7(1):84-91. PMID:11141627


  • Boldyrev AA, Song R, Dyatlov VA, Lawrence DA, Carpenter DO. 2000. Neuronal cell death and reactive oxygen species. Cell Mol Neurobiol 20:433-450. PMID:10901265
  • Carpenter DO. 2000. Human health effects of polychlorinated biphenyls. Cent Eur J Public Health 8(Suppl):23-24. PMID:10943443
  • Carpenter DO, Chew FT, Damstra T, Lam LH, Landrigan PJ, Makalinao I, Peralta GL, Suk WA. 2000. Environmental threats to the health of children: the Asian perspective. Environ Health Perspect 108(10):989-992. PMID:11049821
  • DeCaprio AP, Tarbell A, Bott A, Wagemaker DL, Williams RL, O'Hehir CM. 2000. Routine analysis of 101 polychlorinated biphenyl congeners in human serum by parallel dual-column gas chromatography with electron capture detection. J Anal Toxicol 24(6):403-420. PMID:10999346
  • Gyori Y, Platoshin AV, Carpenter DO, Salanki J. 2000. Effect of inorganic and organic tin compounds on ACh- and voltage-activated Na currents. Cell Mol Neurobiol 20(5):591-604. PMID:10930135
  • Hussain RJ, Gyori Y, DeCaprio AP, Carpenter DO. 2000. In vivo and in vitro exposure to PCB 153 reduces long-term potentiation. Environ Health Perspect 108(9):827-831. PMID:11017886
  • Hussain RJ, Parsons PJ, Carpenter DO. 2000. Effects of lead on long-term potentiation in hippocampal CA3 vary with age. Brain Res Dev Brain Res 121(2):243-252. PMID:10876039
  • Tanji M, Carpenter DO. 2000. A steroid-binding protein mediates estrogen-dependent inhibition of growth of MCF-7 breast cancer cells. Anticancer Res 20(4):2785-2789. PMID:10953358
  • Tanji M, Katz BH, Spink BC, Carpenter DO. 2000. Growth inhibition of MCF-7 cells by estrogen is dependent upon a serum factor. Anticancer Res 20(4):2779-2783. PMID:10953357


  • Ayrapetyan SN, Ayrapetyan G, Carpenter DO. 1999. The electrogenic sodium pump activity in Aplysia neurons is not potential dependent. Acta Biol Hung 50:27-34. PMID:10574426
  • Boldyrev AA, Carpenter DO, Huentelman MJ, Peters CM, Johnson P. 1999. Sources of reactive oxygen species production in excitotoxin- stimulated cerebellar granule cells. Biochem Biophys Res Commun 256(2):320-324. doi:10.1006/bbrc.1999.0325 PMID:10079182
  • Boldyrev AA, Johnson P, Wei Y, Tan Y, Carpenter DO. 1999. Carnosine and taurine protect rat cerebellar granular cells from free radical damage. Neurosci Lett 263(2-3):169-172. doi:10.1016/S0304-3940(99)00150-0 PMID:10213162
  • Bowerman WW, Carey J, Carpenter DO, Colborn T, DeRosa C, Fournier M, Fox GA, Gibson BL, Gilbertson M, Henshel D, McMaster S, Upshur R. 1999. Commentary: Is it time for a separate Great Lakes ecosystem management agreement?. Journal of Great Lakes Research 25(2):237-238. doi:10.1016/S0380-1330(99)70732-X
  • Carpenter DO, Cikrt M, Suk WA. 1999. Hazardous wastes in eastern and central Europe: Technology and health effects. Environ Health Perspect 107(4):249-250. PMID:10090701
  • Fitzgerald EF, Deres DA, Hwang S, Bush B, Yang B, Tarbell A, Jacobs A. 1999. Local fish consumption and serum PCB concentrations among Mohawk men at Akwesasne. Environ Res 80(2Pt2):S97-S103. doi:10.1006/enrs.1998.3908 PMID:10092423


  • Carpenter DO. 1998. Health effects of metals. Cent Eur J Public Health 6:160-163.
  • Carpenter DO. 1998. Human health effects of environmental pollutants: new insights. Environ Monit Assess 53(1):245-258.
  • Carpenter DO. 1998. Polychlorinated biphenyls and human health. Int J Occup Environ Health 11(4):291-303. PMID:10028197
  • Carpenter DO. 1998. Preventing human health hazards from environmental contamination requires interdisciplinary research. In: Proceedings of the Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
  • Carpenter DO, Arcaro KF, Bush B, Niemi WD, Pang S, Vakharia D. 1998. Human health and chemical mixtures: an overview. Environ Health Perspect 106:1263-1270. PMID:9860880
  • Carpenter DO, Blaha K, Buekens A, Cikrt M, Damstra T, Dellinger B, Sarofim A, Suk WA, Wyes H, Zejda J. 1998. Remediation of hazardous wastes in Central and Eastern Europe: technology and health effects. Cent Eur J Public Health 6:77-78.
  • Chiarenzelli J, Scrudato RJ, Bush B, Carpenter DO, Bushart S. 1998. Do large-scale remedial and dredging events have the potential to release significant amounts of semi-volatile compounds to the atmosphere?. Environ Health Perspect 106(2):47-49.
  • DiRienzo AG, Zurbenko IG, Carpenter DO. 1998. Time series analysis of Aplysia total motions activity. Biometrics 54:310-325. PMID:9629641
  • Dyatlov VA, Dyatlova OM, Parsons PJ, Lawrence DA, Carpenter DO. 1998. Lipopolysaccharide and interleukin-6 enhance lead entry into cerebellar neurons: Application of a new and sensitive flow cytometric technique to measure intracellular lead and calcium concentrations. Neurotoxicology 19:293-302. PMID:9553966
  • Dyatlov VA, Makovetskaia VV, Leonhardt R, Lawrence DA, Carpenter DO. 1998. Vitamin E enhances Ca2+-mediated vulnerability of immature cerebellar granule cells to ischemia. Free Radic Biol Med 25(7):793-802. PMID:9823545
  • Dyatlov VA, Platoshin AV, Lawrence DA, Carpenter DO. 1998. Lead potentiates cytokine- and glutamate-mediated increases in permeability of the blood-brain barrier. Neurotoxicology 19:283-292. PMID:9553965
  • Fitzgerald EF, Hwang S, Bush B, Cook K, Worswick P. 1998. Fish consumption and breast milk PCB concentrations among Mohawk women at Akwesasne. Am J Epidemiol 148:164-172. doi:10.1093/oxfordjournals.aje.a009620 PMID:9676698
  • Fitzgerald EF, Schell LM, Marshall EG, Carpenter DO, Suk WA, Zejda J. 1998. Environmental pollution and child health in central and eastern Europe. Environ Health Perspect 106:307-311. PMID:9618345
  • Niemi WD, Audi J, Bush B, Carpenter DO. 1998. PCBs reduce long-term potentiation in the CA1 region of the rat hippocampus. Experimental Neurology 151:26-34. PMID:9582252


  • Carpenter DO, Stoner CT, Lawrence DA. 1997. Flow cytometric measurements of neuronal death triggered by PCBs. Neurotoxicology 18(2):507-513. PMID:9291498


  • Carpenter DO. 1996. New dimensions in our understanding of the human health effects of environmental pollutants. In: Proceedings of the Pacific Basin Conference on Hazardous Waste, November 4-8, 1996, Kuala Lumpur, Malaysia. East-West Center, Kuala Lumpur, Malaysia. pp.37-53.
  • Carpenter DO, Stoner CT, Lawrence DA, Niemi WD, Shain W, Seegal R. 1996. Multiple mechanisms of PCB neurotoxicity. In: Proceedings of the Pacific Basin Conference on Hazardous Waste, November 4-8, 1996, Kuala Lumpur, Malaysia. East-West Center, Kuala Lumpur, Malaysia. pp.404-418.
  • Carpenter DO, Suk WA, Blaha K, Cikrt M. 1996. Hazardous wastes in Eastern and Central Europe. Environ Health Perspect 104(3):244-248. PMID:8919756


  • Carpenter DO. 1995. Communicating with the public on issues of science and public health. Environ Health Perspect 141-144. PMID:8549459
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