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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: University of Arizona: Susceptibility to Trichloroethylene (TCE) and Chlorinated Acids in Heart Development

Superfund Research Program

Susceptibility to Trichloroethylene (TCE) and Chlorinated Acids in Heart Development

Project Leader: Ornella Selmin
Grant Number: P42ES004940
Funding Period: 2000-2010

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Publications

2010

  • Caldwell P, Manziello A, Howard J, Palbykin B, Runyan RB, Selmin O. 2010. Gene expression profiling in the fetal cardiac tissue after folate and low dose trichloroethylene exposure. Birth Defects Res A Clin Mol Teratol 88(2):111-127. doi:10.1002/bdra.20631 PMID:19813261 PMCID:PMC4045246

2008

  • Caldwell P, Thome PA, Johnson PD, Boitano S, Runyan RB, Selmin O. 2008. Trichloroethylene disrupts cardiac gene expression and calcium homeostasis in rat myocytes. Toxicol Sci 104(1):135-143. doi:10.1093/toxsci/kfn078 PMID:18411232 PMCID:PMC4001797
  • Petrick JS, Blachere FM, Selmin O, Lantz RC. 2008. Inorganic arsenic as a developmental toxicant: in utero exposure and alterations in the developing rat lungs. Mol Nutr Food Res 53(5):583-591. PMID:19072884
  • Selmin O, Thome PA, Caldwell P, Taylor MR. 2008. Trichloroethylene and trichloroacetic acid regulate calcium signaling pathways in murine embryonal carcinoma cells pl9. Cardiovasc Toxicol 8(2):47-56.

2006

  • Romagnolo DF, Degner SC, Kemper MQ, Hockings J, Selmin O. 2006. Role of dietary xenobiotics-gene interactions in carcinogenesis: protective effects of nutritional factors. Current Nutrition & Food Science 2(3):205-214.

2005

  • Selmin O, Thorne PA, Caldwell P, Johnson PD, Runyan RB. 2005. Effects of trichloroethylene and its metabolite trichloroacetic acid on the expression of vimentin in the rat H9c2 cell line. Cell Biol Toxicol 21(2):83-95. PMID:16142583

2003

  • Collier JM, Selmin O, Johnson PD, Runyan RB. 2003. Trichloroethylene effects on gene expression during cardiac development. Birth Defects Res A Clin Mol Teratol 67(7):488-495. doi:10.1002/bdra.10073 PMID:14565619

2002

  • Blachere FM, Thorne PA, Johnson PD, Runyan RB, Selmin O. 2002. TCE-exposed enbryonic heart. In: Proceedings of the Science Fair 2002, (Superfund Basic Research Program) SBRP and SWEHSC (Southwest Environmental Health Sciences Center), May 17. University of Arizona, Tucson, AZ.
  • Blachere FM, Thorne PA, Johnson PD, Runyan RB, Selmin O. 2002. TCE-mediated regulation of SERCA2a. In: Proceedings of the Science Fair 2002, (Superfund Basic Research Program) SBRP and SWEHSC (Southwest Environmental Health Sciences Center), May 17. University of Arizona, Tucson, AZ.
  • Petrick JS, Blachere FM, Greer KA, Schwartz MA, Scholz MJ, Selmin O, Runyan RB, Hoying JB, Lantz RC. 2002. Arsenic targets the developing rat lung: gene expression alterations following chronic low-dose exposure. In: Symposium on Arsenic in New England, May 29-31. Manchester, NH.
  • Petrick JS, Blachere FM, Greer KA, Schwartz MA, Scholz MJ, Selmin O, Runyan RB, Hoying JB, Lantz RC. 2002. Chronic low-level arsenic exposure induces aberrant gene expression in the lung. In: Proceedings of the Fifth International Conference on Arsenic Exposure and Health Effects, July 14-18. San Diego, CA.
  • Petrick JS, Blachere FM, Selmin O, Runyan RB, Lantz RC. 2002. Arsenic induces aberrant gene expression during lung development: Application of toxicogenomics. In: Proceedings of the 41st Annual Meeting of the Society of Toxicology (SOT), March 17-21, 2002. Nashville, TN.
  • Petrick JS, Blachere FM, Selmin O, Runyan RB, Lantz RC. 2002. Arsenic induces aberrant gene expression during lung development: Application of toxicogenomics. In: Proceedings of the Science Fair 2002, (Superfund Basic Research Program) SBRP and SWEHSC (Southwest Environmental Health Sciences Center), May 17. University of Arizona, Tucson, AZ. pp.10.
  • Scholz MJ, Kulkarni A, Yu C, Selmin O, Runyan RB, Mathine D. 2002. CMOS Biochip for rapid assessment of chemical toxicity. In: Proceedings of the Science Fair 2002, (Superfund Basic Research Program) SBRP and SWEHSC (Southwest Environmental Health Sciences Center), May 17. University of Arizona, Tucson, AZ. pp.45.

2001

  • Fisher JW, Channel SR, Eggers JS, Johnson PD, MacMahon KL, Goodyear CD, Sudberry GL, Warren DA, Latendresse JR, Graeter LJ. 2001. Trichloroethylene, trichloroacetic acid, and dichloroacetic acid: do they affect fetal rat heart development?. International Toxicological Sciences 20(5):257-267. PMID:11766123

2000

  • Boyer AS, Finch WT, Runyan RB. 2000. Trichloroethylene inhibits development of embryonic heart valve precursors in vitro. Toxicol Sci 53(1):109-117. PMID:10653528

1999

  • Eggers JS, Channel SR, Graeter LJ, Johnson PD, MacMahon KL, Sudberry GL, Warren DA, Latendresse JR. 1999. Use of hematoxylin stain to enhance evaluation of heart malformations in the fetal rat. Teratology 59:173-175. PMID:10194808
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