Superfund Research Program

Research Experience and Training Coordination Core

Project Leader: Raina M. Maier
Co-Investigator: Monica Ramirez-Andreotta
Grant Number: P42ES004940
Funding Period: 1995-2025

Project-Specific Links

Publications

2023

• Anandhan A, Dodson M, Shakya A, Chen J, Liu P, Wei Y, Tan H, Wang Q, Jiang Z, Yang K, Garcia JG, Chambers SK, Chapman E, Ooi A, Yang-Hartwich Y, Stockwell BR, Zhang DD. 2023. NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8. Sci Adv 9(5):doi:10.1126/sciadv.ade9585 PMID:36724221 PMCID:PMC9891695
• Dai M, Yan N, Brusseau ML. 2023. Potential impact of bacteria on the transport of PFAS in porous media. Water Res 243:120350. doi:10.1016/j.watres.2023.120350 PMID:37499541 PMCID:PMC10530518
• Huerta D, Schobel T, Alexander-Ozinskas A, Hild J, Lauder J, Reynolds P, Von Behren J, Meltzer D, Ramirez-Andreotta M. 2023. Probabilistic risk assessment of residential exposure to metal(loid)s in a mining impacted community. Sci Total Environ 872:162228. doi:10.1016/j.scitotenv.2023.162228 PMID:36791848 PMCID:PMC1002350
• Kushwaha P, Tran A, Quintero D, Song M, Yu Q, Yu RT, Downes M, Evans RM, Babst-Kostecka AA, Schroeder JI, Maier RM. 2023. Zinc accumulation in Atriplex lentiformis is driven by plant genes and the soil microbiome. Sci Total Environ 899:165667. doi:10.1016/j.scitotenv.2023.165667 PMID:37478925
• McCawley IA, Maier RM, Hogan DE. 2023. Comparison of synthetic rhamnolipids as chemical precipitants for Pb, La, and Mg. J Hazard Mater 447:130801. doi:10.1016/j.jhazmat.2023.130801 PMID:36689902 PMCID:PMC9986113
• Ossanna LQ, Serrano K, Jennings LL, Dillon J, Maier RM, Neilson JW. 2023. Progressive belowground soil development associated with sustainable plant establishment during copper mine waste revegetation. Applied Soil Ecology 186:104813. doi:10.1016/j.apsoil.2023.104813 PMID:36844191 PMCID:PMC9956965
• Shakya A, Dodson M, Artiola JF, Ramirez-Andreotta M, Root RA, Ding X, Chorover J, Maier RM. 2023. Arsenic in drinking water and diabetes. Water (Basel) 15(9):1751. doi:10.3390/w15091751
• Shakya A, Mckee NW, Dodson M, Chapman E, Zhang DD. 2023. Anti-ferroptotic effects of Nrf2: beyond the antioxidant response. Mol Cells 46(3):165-175. doi:10.14348/molcells.2023.0005 PMID:36994475 PMCID:PMC10070163
• Stanek M, Kushwaha P, Murawska-Wlodarczyk K, Stefanowicz AM, Babst-Kostecka AA. 2023. Quercus rubra invasion of temperate deciduous forest stands alters the structure and functions of the soil microbiome. Geoderma 430:116328. doi:10.1016/j.geoderma.2023.116328
• Van Horne YO, Carroll S, Chief K, Lothrop N, Richards JR, Begay M, Charley PH, Ingram J, Beamer P. 2023. Using environmental health dialogue in a Dine-centered approach for individualized results reporting in an environmental exposure study following the Gold King Mine Spill. Environ Res 231(Pt.2):116196. doi:10.1016/j.envres.2023.116196 PMID:37211184 PMCID:PMC10411314
• Zeider K, Manjon I, Betterton EA, Saez AE, Sorooshian A, Ramirez-Andreotta M. 2023. Backyard aerosol pollution monitors: foliar surfaces, dust enrichment, and factors influencing foliar retention. Environ Monit Assess 195(10):1200. doi:10.1007/s10661-023-11752-2 PMID:37700111 PMCID:PMC10636967

2022

• Anandhan A, Chen W, Nguyen N, Madhavan L, Dodson M, Zhang DD. 2022. Alpha-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease. Free Radic Biol Med 192:130-140. doi:10.1016/j.freeradbiomed.2022.09.015 PMID:36150560
• Hannon SL, Ding X. 2022. Assessing cytochrome P450 function using genetically engineered mouse models. Adv Pharmacol 95:253-284. doi:10.1016/bs.apha.2022.05.008 PMID:35953157 PMCID:10544722
• Schiro G, Liu P, Dodson M, Zhang DD, Ghishan FK, Barberan A, Kiela PR. 2022. Interactions between arsenic exposure, high-fat diet and NRF2 shape the complex responses in the murine gut microbiome and hepatic metabolism. Front Microbiomes 1:doi:10.3389/frmbi.2022.1041188

2021

• Brusseau ML, Guo B, Huang D, Yan N, Lyu Y. 2021. Ideal versus nonideal transport of PFAS in unsaturated porous media. Water Res 202:117405. doi:10.1016/j.watres.2021.117405 PMID:34273774
• Brusseau ML, Van Glubt S. 2021. The influence of molecular structure on PFAS adsorption at air-water interfaces in electrolyte solutions. Chemosphere 281:doi:10.1016/j.chemosphere.2021.130829 PMID:33992851 (ahead of print)
• Dietrich CC, Tandy S, Murawska-Wlodarczyk K, Banas A, Korzeniak U, Seget B, Babst-Kostecka AA. 2021. Phytoextraction efficiency of Arabidopsis halleri is driven by the plant and not by soil metal concentration. Chemosphere 285(10):131437. doi:10.1016/j.chemosphere.2021.131437 PMID:34265706 PMCID:PMC8551008
• El Ouni A, Guo B, Zhong H, Brusseau ML. 2021. Testing the validity of the miscible-displacement interfacial tracer method for measuring air-water interfacial area: Independent benchmarking and mathematical modeling. Chemosphere 263:128193. doi:10.1016/j.chemosphere.2020.128193 PMID:33184521 PMCID:PMC7654622 (ahead of print)
• Heusinkveld D, Ramirez-Andreotta M, Rodriguez-Chavez TB, Saez AE, Betterton EA, Rine K. 2021. Assessing children's lead exposure in an active mining community using the integrated exposure uptake biokinetic model. Expo Health 17:doi:10.1007/s12403-021-00400-0 PMID:34532608 PMCID:PMC8439183
• Liu P, Dodson M, Li H, Schmidlin C, Shakya A, Wei Y, Garcia JG, Chapman E, Kiela PR, Zhang Q, White E, Ding X, Ooi A, Zhang DD. 2021. Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism. Mol Metab 51:101243. doi:10.1016/j.molmet.2021.101243 PMID:33933676 PMCID:PMC8164084
• Ramirez-Andreotta M, Walls R, Youens-Clark K, Blumberg K, Isaacs K, Kaufmann D, Maier RM. 2021. Alleviating environmental health disparities through community science and data integration. Front Sustain Food Sys 5:620470. doi:10.3389/fsufs.2021.620470 PMID:35664667 PMCID:PMC9165534
• Schmidlin C, Shakya A, Dodson M, Chapman E, Zhang DD. 2021. The intricacies of NRF2 regulation in cancer. Semin Cancer Biol 76:110-119. doi:10.1016/j.semcancer.2021.05.016 PMID:34020028 PMCID:PMC8599504
• Schmidlin C, Tian W, Dodson M, Chapman E, Zhang DD. 2021. FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells. Mol Carcinog doi:10.1002/mc.23295 PMID:33684228 PMCID:PMC8189631
• Van Glubt S, Brusseau ML, Yan N, Huang D, Khan N, Carroll KC. 2021. Column versus batch methods for measuring PFOS and PFOA sorption to geomedia. Environ Pollut 268:115917. doi:10.1016/j.envpol.2020.115917 PMID:33143983 PMCID:PMC7746577
• Van Horne YO, Chief K, Charley PH, Begay M, Lothrop N, Bell ML, Canales RA, Teufel-Shone NI, Beamer P. 2021. Impacts to Dine activities with the San Juan River after the Gold King Mine Spill. J Expo Sci Environ Epidemiol 31(5):doi:10.1038/s41370-021-00290-z PMID:33526814 (ahead of print)
• Wang Y, Khan N, Huang D, Carroll KC, Brusseau ML. 2021. Transport of PFOS in aquifer sediment: Transport behavior and a distributed-sorption model. Sci Total Environ 779:146444. doi:10.1016/j.scitotenv.2021.146444 PMID:33740555
• Zeider K, Van Overmeiren N, Rine K, Sandhaus S, Saez AE, Sorooshian A, Munoz HC, Ramirez-Andreotta M. 2021. Foliar surfaces as dust and aerosol pollution monitors: An assessment by a mining site. Sci Total Environ 790:148164. doi:10.1016/j.scitotenv.2021.148164 PMID:34380246 PMCID:PMC8362843

2020

• Kushwaha P, Neilson JW, Barberan A, Chen Y, Fontana CG, Butterfield BJ, Maier RM. 2020. Arid ecosystem vegetation canopy-gap dichotomy: Influence on soil microbial composition and nutrient cycling functional potential. Appl Environ Microbiol 87(5):doi:10.1128/AEM.02780-20 PMID:33310716 (ahead of print)
• Liu P, Dodson M, Fang D, Chapman E, Zhang DD. 2020. NRF2 negatively regulates primary ciliogenesis and hedgehog signaling. PLoS Biol 18(2):doi:10.1371/journal.pbio.3000620 PMID:32053600 PMCID:PMC7043785
• Manjon I, Ramirez-Andreotta M, Saez AE, Root RA, Hild J, Janes MK, Alexander-Ozinskas A. 2020. Environmental monitoring and exposure science dataset to calculate ingestion and inhalation of metal(loid)s through preschool gardening. Data Brief 29:105050. doi:10.1016/j.dib.2019.105050 PMID:32055651 PMCID:PMC7005369
• Michel-Ramirez G, Recio-Vega R, Lantz RC, Gandolfi A, Olivas-Calderon E, Chau BT, Amistadi M. 2020. Assessment of YAP gene polymorphisms and arsenic interaction in Mexican women with breast cancer. J Appl Toxicol 40(3):342-351. doi:10.1002/jat.3907 PMID:31631368 PMCID:PMC7012748

2019

• Brusseau ML, Khan N, Wang Y, Yan N, Van Glubt S, Carroll KC. 2019. Nonideal transport and extended elution tailing of PFOS in soil. Environ Sci Technol 53(18):10654-10664. doi:10.1021/acs.est.9b02343 PMID:31464435 PMCID:PMC6830724
• Brusseau ML, Yan N, Van Glubt S, Wang Y, Chen W, Lyu Y, Dungan B, Carroll KC, Holguin F. 2019. Comprehensive retention model for PFAS transport in subsurface systems. Water Res 148:41-50. doi:10.1016/j.watres.2018.10.035 PMID:30343197 PMCID:PMC6294326
• Dodson M, Castro-Portuguez R, Zhang DD. 2019. NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis. Redox Biol 23:101107. doi:10.1016/j.redox.2019.101107 PMID:30692038 PMCID:PMC6859567
• Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD. 2019. Modulating NRF2 in disease: timing is everything. Annu Rev Pharmacol Toxicol 59:555-575. doi:10.1146/annurev-pharmtox-010818-021856 PMID:30256716 PMCID:PMC6538038
• Hottenstein JD, Neilson JW, Gil-Loaiza J, Root RA, White SA, Chorover J, Maier RM. 2019. Soil microbiome dynamics during pyritic mine tailing phytostabilization: understanding microbial bioindicators of soil acidification. Front Microbiol 10:doi:10.3389/fmicb.2019.01211 PMID:31275251 PMCID:PMC6593306
• Liu P, de la Vega MR, Dodson M, Yue F, Shi B, Fang D, Chapman E, Liu L, Zhang DD. 2019. Spermidine confers liver protection by enhancing NRF2 signaling through a MAP1S-mediated noncanonical mechanism. Hepatology 70(1):372-388. doi:10.1002/hep.30616 PMID:30873635 PMCID:PMC6597327
• Moreno-Andrade I, Regidor-Alfageme E, Durazo A, Field JA, Umlauf K, Sierra-Alvarez R. 2019. LC-ICP-OES method for antimony speciation analysis in liquid samples. J Environ Sci Health A Tox Hazard Subst Environ Eng doi:10.1080/10
• Ramirez-Andreotta M, Tapper AE, Clough D, Carrera J, Sandhaus S. 2019. Understanding the intrinsic and extrinsic motivations associated with community gardening to improve environmental public health prevention and intervention. Int J Environ Res Public Health 16(3):494. doi:10.3390/ijerph16030494 PMID:30754611 PMCID:PMC6388228
• Schmidlin CJ, Dodson M, Madhavan L, Zhang DD. 2019. Redox regulation by NRF2 in aging and disease. Free Radic Biol Med 134:702-707. doi:10.1016/j.freeradbiomed.2019.01.016 PMID:30654017 PMCID:PMC6588470
• Yan N, Zhong H, Brusseau ML. 2019. The natural activation ability of subsurface media to promote in-situ chemical oxidation of 1,4-dioxane. Water Res 149:386-393. doi:10.1016/j.watres.2018.11.028 PMID:30471534 PMCID:PMC6358466

2018

• Dodson M, de la Vega MR, Harder B, Castro-Portuguez R, Rodrigues SD, Wong PK, Chapman E, Zhang DD. 2018. Low-level arsenic causes proteotoxic stress and not oxidative stress. Toxicol Appl Pharmacol 341:106-113. doi:10.1016/j.taap.2018.01.014 PMID:29408041 PMCID:PMC5929483
• Hossein Mardi A, Khaghani A, MacDonald AB, Nguyen P, Karimi N, Heidary P, Karimi N, Saemian P, Sehatkashani S, Tajrishy M, Sorooshian A. 2018. The Lake Urmia environmental disaster in Iran: A look at aerosol pollution. Sci Total Environ 633:42-49. doi:10.1016/j.scitotenv.2018.03.148 PMID:29573690 PMCID:PMC5949080
• Liu P, de la Vega MR, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JG, Zhang DD. 2018. RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Proc Natl Acad Sci U S A 115(44):E10352-E10361. doi:10.1073/pnas.1812125115 PMID:30309964 PMCID:PMC6217430
• Lyu Y, Brusseau ML, Chen W, Yan N, Fu X, Lin X. 2018. Adsorption of PFOA at the air-water interface during transport in unsaturated porous media. Environ Sci Technol 52:7745-7753. doi:10.1021/acs.est.8b02348 PMID:29944343
• Madeira CL, Field JA, Simonich MT, Tanguay RL, Chorover J, Sierra-Alvarez R. 2018. Ecotoxicity of the insensitive munitions compound 3-nitro-1,2,4-triazol-5-one (NTO) and its reduced metabolite 3-amino-1,2,4-triazol-5-one (ATO). J Hazard Mater 343:340-346. doi:10.1016/j.jhazmat.2017.09.052 PMID:28992572
• Yan N, Liu F, Liu B, Brusseau ML. 2018. Treatment of 1,4-dioxane and trichloroethene co-contamination by an activated binary persulfate-peroxide oxidation process. Environ Sci Pollut Res Int 1-8. doi:10.1007/s11356-018-3153-1 PMID:30218336 PMCID:PMC6367011

2017

• Bao L, Wu J, Dodson M, de la Vega MR, Ning Y, Zhang Z, Yao M, Zhang DD, Xu C, Yi X. 2017. ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. Mol Carcinog 56(6):1543-1553. doi:10.1002/mc.22615 PMID:28112439 PMCID:PMC5509336
• Braun RA, Dadashazar H, MacDonald AB, Aldhaif AA, Maudlin LC, Crosbie E, Azadi Aghdam M, Hossein Mardi A, Sorooshian A. 2017. Impact of wildfire emissions on chloride and bromide depletion in marine aerosol particles. Environ Sci Technol 51:9013-9021. doi:10.1021/acs.est.7b02039 PMID:28700243 (accepted for publication)
• Lyu Y, Brusseau ML, El Ouni A, Araujo JB, Su X. 2017. The gas-absorption/chemical-reaction method for measuring air-water interfacial area in natural porous media. Water Resour Res 53:9519-9527. doi:10.1002/2017WR021717 PMID:29662253 PMCID:PMC5898451
• Madeira CL, Speet SA, Alvarez-Nieto C, Abrell L, Chorover J, Sierra-Alvarez R, Field JA. 2017. Sequential anaerobic-aerobic biodegradation of emerging insensitive munitions compound 3-nitro-1,2,4-triazol-5-one (NTO). Chemosphere 167:478-484. doi:10.1016/j.chemosphere.2016.10.032 PMID:27750172
• Ramos-Ruiz A, Sesma-Martin J, Sierra-Alvarez R, Field JA. 2017. Continuous reduction of tellurite to recoverable tellurium nanoparticles using an upflow anaerobic sludge bed (UASB) reactor. Water Res 108:189-196. doi:10.1016/j.watres.2016.10.074 PMID:27825682

2016

• Gil-Loaiza J, White SA, Root RA, Ramirez-Solis A, Hammond C, Chorover J, Maier RM. 2016. Phytostabilization of mine tailings using compost-assisted direct planting: translating greenhouse results to the field. Sci Total Environ 565:451-461. doi:10.1016/j.scitotenv.2016.04.168 PMID:27183459 PMCID:PMC4921306
• Honeker LK, Root RA, Chorover J, Maier RM. 2016. Resolving colocalization of bacteria and metal(loid)s on plant root surfaces by combining fluorescence in situ hybridization (FISH) with multiple-energy micro-focused X-ray fluorescence (ME μXRF). J Microbiol Methods 131:23-33. doi:10.1016/j.mimet.2016.09.018 PMID:27693754 PMCID:PMC5127750
• Mora Ramirez M, Dadashazar H, MacDonald AB, Crosbie E, Bates KH, Coggon MM, Craven JS, Lynch P, Campbell JR, Azadi Aghdam M, Woods RK, Jonsson H, Flagan RC, Seinfeld JH, Sorooshian A, Wang Z. 2016. Contrasting cloud composition between coupled and decoupled marine boundary layer clouds. J Geophys Res Atmos 121:11679-11691. doi:10.1002/2016JD025695
• Olivares CI, Abrell L, Khatiwada R, Chorover J, Sierra-Alvarez R, Field JA. 2016. (Bio)transformation of 2,4-dinitroanisole (DNAN) in soils. J Hazard Mater 304:214-221. doi:10.1016/j.jhazmat.2015.10.059 PMID:26551225 PMCID:PMC4695256
• Olivares CI, Field JA, Simonich MT, Tanguay RL, Sierra-Alvarez R. 2016. Arsenic (III, V), indium (III), and gallium (III) toxicity to zebrafish embryos using a high-throughput multi-endpoint in vivo developmental and behavioral assay. Chemosphere 148:361-368. doi:10.1016/j.chemosphere.2016.01.050 PMID:26824274 PMCID:PMC4754138
• Ramos-Ruiz A, Field JA, Wilkening JV, Sierra-Alvarez R. 2016. Recovery of elemental tellurium nanoparticles by the reduction of tellurium oxyanions in a methanogenic microbial consortium. Environ Sci Technol 50(3):1492-1500. doi:10.1021/acs.est.5b04074 PMID:26735010 PMCID:PMC4738100
• Ramos-Ruiz A, Zeng C, Sierra-Alvarez R, Teixeira LH, Field JA. 2016. Microbial toxicity of ionic species leached from the II-VI semiconductor materials, cadmium telluride (CdTe) and cadmium selenide (CdSe). Chemosphere 162:131-138. doi:10.1016/j.chemosphere.2016.07.081 PMID:27494313 PMCID:PMC5003732
• Yan N, Liu F, Chen Y, Brusseau ML. 2016. Influence of groundwater constituents on 1,4-dioxane degradation by a binary oxidant system. Water Air Soil Pollut 227:436. doi:10.1007/s11270-016-3146-y PMID:28943674 PMCID:PMC5603204