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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Project Publications: Cornell University: Dogs as a Model for Assessment of Immunotoxicity of Environmental Pollutants

Superfund Research Program

Dogs as a Model for Assessment of Immunotoxicity of Environmental Pollutants

Project Leader: Fred W. Quimby
Grant Number: P42ES005950
Funding Period: 1995 - 2000
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

Project-Specific Links

Publications

2005

  • Quimby FW, Casey AC, Arquette MF. 2005. From dogs to frogs: how pets, laboratory animals, and wildlife aided in elucidating harmful effects arising from a hazardous dumpsite. ILAR J 46(4):364-369. PMID:16179745

2002

  • Savage WK, Quimby FW, DeCaprio AP. 2002. Lethal and sublethal effects of polychlorinated biphenyls on rana sylvatica tadpoles. Environ Toxicol Chem 21(1):168-174. PMID:11804051

2000

  • Korytko PJ, Quimby FW, Scott JG. 2000. Metabolism of phenanthrene by house fly CYP6D1 and dog liver cytochrome P450. J Biochem Mol Toxicol 14(1):20-25. PMID:10561078

1999

  • Casey AC, Berger D, Lombardo JP, Hunt A, Quimby FW. 1999. Aroclor 1242 inhalation and ingestion by Sprague-Dawley rats. J Toxicol Environ Health A 56(5):311-342. PMID:10094245
  • Korytko PJ, Casey AC, Bush B, Quimby FW. 1999. Induction of hepatic cytochrome P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls. Toxicol Sci 47(1):52-61. PMID:10048153
  • Loeb W, Quimby FW. 1999. The Clinical Chemistry of Laboratory Animals, Second Edition. In: Taylor and Francis. Philadelphia, PA. Taylor and Francis, Philadelphia, PA.
  • Savage WK, Quimby FW. 1999. Effects of PCB Contaminated Sediment on Larval Amphibian Growth and Development. In: Proceedings of the Great Plains/Rocky Mountain Hazardous Substance Research Meeting. St. Louis, MO.
  • Thurmond TS, Silverstone AW, Baggs RB, Quimby FW, Staples JE, Gasiewcz TA. 1999. A chimeric Ah receptor knockout mouse model indicates that hematopoietic cells contribute to the hepatic lesions induced by 2,3, 7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 158:33-40. PMID:10387930
  • Twersky T, Reimers T, Quimby FW. 1999. Changes in pituitary lactotrope numbers and prolactin secretion in dogs exposed to PCBs. Superfund Notes 5(1):1-5.

1998

  • Olsen J, Quimby FW. 1998. In vitro Model for PCB-induced Immunosuppression. In: Proceedings of the NIEHS/EPA (National Institute Environmental Health Sciences/Environmental Protection Agency) Superfund Basic Research Program Conference, 1998. Massachusetts Institute of Technology (MIT), Cambridge, MA.

1997

  • Cohen JE, Morin D, Cornell K, Ruane E, Quimby FW. 1997. Pathophysiology of PCB-induced humoral immunosuppression in dogs. In: Proceedings of A Decade of Improved Health Through Multidisciplinary Research, NIEHS (National Institute of Environmental Health Sciences). Durham, NC.
  • Fadden M, Gardhi S, Reimeis T, Quimby FW. 1997. Changes in thyroxine metabolism associated with PCBs in dogs. In: Proceedings of A Decade of Improved Health Through Multidisciplinary Research, NIEHS (National Institute of Environmental Health Sciences). Durham, NC.
  • Korytko PJ, Casey AC, Bush B, Quimby FW. 1997. Induction of Hepatic Cytochrome P450 in Dogs Exposed to a Chronic Low Dose of PCBs. In: Proceedings of the 17th International Congress on Biochemistry and Molecular Biology. San Francisco, CA.

1996

  • Rivas AL, Letwin B, Greenlee P, Lopez J, Fadden M, Quimby FW. 1996. Characterization of monoclonal antibodies directed to canine T lymphocyte markers expressed during development. Vet Immunol Immunopathol 51(1-2):1-11. doi:10.1016/0165-2427(95)05500-2 PMID:8797271

1995

  • Morin D. 1995. Effects of Polychlorinated Biphenyls on the Primary Immune Response in Canis Familiaris. B.S. Honors Thesis, Cornell University, Ithaca, NY.
  • Quimby FW. 1995. Immunologic and endocrinologic effects of chronic low dose Aroclor 1248 exposure in dogs. In: Proceedings of the 1995 Great Lakes Research Consortium.
  • Quimby FW. 1995. Immunotoxic effects of PCBs using dogs as a model. In: Proceedings of the Superfund Basic Research Meeting, 1995. State University of New York(SUNY), Oswego, NY.
  • Rivas AL, Kimball ES, Quimby FW, Gebhard W. 1995. Functional and phenotypic analysis of in vitro stimulated canine peripheral blood mononuclear cells. Vet Immunol Immunopathol 45:55-71. PMID:7604538
  • Roberts MA, Durst RA. 1995. Investigation of liposome-based immunomigration sensors for the detection of polychlorinated biphenyls. Anal Chem 67:482-491. PMID:7892998

1994

  • Fadden M. 1994. Domestic Dogs As Sentinels of Health. Ph.D. Thesis, Cornell University, Ithaca, NY.
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