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Your Environment. Your Health.

Project Publications: Dartmouth College: Training Core

Superfund Research Program

Training Core

Project Leader: Bruce A. Stanton
Grant Number: P42ES007373
Funding Period: 2000-2021

Project-Specific Links



  • Doherty BT, Koelmel J, Lin EZ, Romano M, Godri Pollitt KJ. 2021. Use of Exposomic Methods Incorporating Sensors in Environmental Epidemiology. Curr Environ Health Rep 8:1-8. doi:10.1007/s40572-021-00306-8 PMID:33569731


  • Doherty BT, Kosarek N, Hoofnagle A, Xu Y, Zoeller RT, Yolton K, Chen A, Lanphear BP, Braun JM, Romano M. 2020. Maternal, cord, and three-year-old child serum thyroid hormone concentrations in the Health Outcomes and Measures of the Environment study. Clin Endocrinol (Oxf) 92:366-372. doi:10.1111/cen.14151 PMID:31901217 PMCID:PMC7251780
  • Doherty BT, Pearce JL, Anderson KA, Karagas MR, Romano M. 2020. Assessment of multipollutant exposures during pregnancy using silicone wristbands. Front Public Health 8:547239. doi:10.3389/fpubh.2020.547239 PMID:33117768 PMCID:PMC7550746
  • Doherty BT, Romano M, Gui J, Punshon T, Jackson BP, Karagas MR, Korrick SA. 2020. Periconceptional and prenatal exposure to metal mixtures in relation to behavioral development at 3 years of age. Environ Epidemiol 4:doi:10.1097/EE9.0000000000000106 PMID:33154986 PMCID:PMC7595192
  • Hsu KS, Goodale BC, Ely KH, Hampton TH, Stanton BA, Enelow RI. 2020. Single-cell RNA-seq analysis reveals that prenatal arsenic exposure results in long-term, adverse effects on immune gene expression in response to Influenza A infection. Toxicol Sci 176:312-328. doi:10.1093/toxsci/kfaa080 PMID:32514536 PMCID:PMC7416320
  • Lebeaux RM, Doherty BT, Gallagher LG, Zoeller RT, Hoofnagle A, Calafat AM, Karagas MR, Yolton K, Chen A, Lanphear BP, Braun JM, Romano M. 2020. Maternal serum perfluoroalkyl substance mixtures and thyroid hormone concentrations in maternal and cord sera: The HOME Study. Environ Res 185:doi:10.1016/j.envres.2020.109395 PMID:32222633 PMCID:PMC7657649


  • Goodale BC, Hampton TH, Notch EG, Jackson CE, Shaw JR, Stanton BA, King BL. 2019. Profiling microRNA expression in Atlantic killifish (Fundulus heteroclitus) gill and responses to arsenic and hyperosmotic stress. Aquat Toxicol 206:142-153. doi:10.1016/j.aquatox.2018.11.009 PMID:30476744 PMCID:PMC6298807
  • Signes-Pastor AJ, Doherty BT, Romano M, Gleason K, Gui J, Baker E, Karagas MR. 2019. Prenatal exposure to metal mixture and sex-specific birth outcomes in the new hampshire birth cohort study. Environ Epidemiol 3:e068. doi:10.1097/EE9.0000000000000068 PMID:31844832 PMCID:PMC6914313
  • Signes-Pastor AJ, Vioque J, Navarrete-Munoz EM, Carey M, Garcia-Villarino M, Fernandez-Somoano A, Tardon A, Santa-Marina L, Irizar A, Casas M, Guxens M, Llop S, Soler-Blasco R, Garcia-de-la-Hera M, Karagas MR, Meharg AA. 2019. Inorganic arsenic exposure and neuropsychological development of children of 4-5 years of age living in Spain. Environ Res 174:135-142. doi:10.1016/j.envres.2019.04.028 PMID:31075694 PMCID:PMC6541502 (ahead of print)
  • Signes-Pastor AJ, Zens MS, Seigne JD, Schned AR, Karagas MR. 2019. Rice consumption and incidence of bladder cancer in a United States population. Epidemiology 30(2):e4-e5. doi:10.1097/ede.0000000000000955 PMID:30721170 PMCID:PMC6368392


  • Buckman KL, Lane O, Kotnik J, Bratkic A, Sprovieri F, Horvat M, Pirrone N, Evers DC, Chen CY. 2018. Spatial and taxonomic variation of mercury concentration in low trophic level fauna from the Mediterranean Sea. Ecotoxicology 1-12. doi:10.1007/s10646-018-1986-5 PMID:30315417
  • Hampton TH, Jackson CE, Jung D, Chen CY, Glaholt SP, Stanton BA, Colbourne JK, Shaw JR. 2018. Arsenic reduces gene expression response to changing salinity in killifish. Environ Sci Technol 52:8811-8821. doi:10.1021/acs.est.8b01550 PMID:29979584 PMCID:PMC6084426
  • Lee C, Fisher NS. 2018. Microbial generation of elemental mercury from dissolved methylmercury in seawater. Limnology and Oceanography 64(2):679-693. doi:10.1002/lno.11068 PMID:31105337 PMCID:PMC6519744
  • Liu M, Chen L, He Y, Baumann Z, Mason RP, Shen H, Yu C, Zhang W, Zhang Q, Wang X. 2018. Impacts of farmed fish consumption and food trade on methylmercury exposure in China. Environ Int 120:333-344. doi:10.1016/j.envint.2018.08.017 PMID:30114623
  • Liu M, Zhang Q, Luo Y, Mason RP, Ge S, He Y, Yu C, Sa R, Cao H, Wang X, Chen L. 2018. Impact of water-induced soil erosion on the terrestrial transport and atmospheric emission of mercury in China. Environ Sci Technol 52:6945-6956. doi:10.1021/acs.est.8b01319 PMID:29785847 PMCID:PMC6036913
  • Nachman KE, Punshon T, Rardin LR, Signes-Pastor AJ, Murray CJ, Jackson BP, Guerinot ML, Burke TA, Chen CY, Ahsan H, Argos M, Cottingham KL, Cubadda F, Ginsberg GL, Goodale BC, Kurzius-Spencer M, Meharg AA, Miller M, Nigra AE, Pendergrast CB, Raab A, Reimer K, Scheckel KG, Schwerdtle T, Taylor VF, Tokar EJ, Warczak TM, Karagas MR. 2018. Opportunities and challenges for dietary arsenic intervention. Environ Health Perspect 126(8):084503-1-6. doi:10.1289/EHP3997 PMID:30235424 PMCID:PMC6375412
  • Seelen EA, Massey GM, Mason RP. 2018. Role of sediment resuspension on estuarine suspended particulate mercury dynamics. Environ Sci Technol 52:7736-7744. doi:10.1021/acs.est.8b01920 PMID:29927238 PMCID:PMC6051696
  • Taylor VF, Buckman KL, Seelen EA, Mazrui NM, Balcom PH, Mason RP, Chen CY. 2018. Organic carbon content drives methylmercury levels in the water column and in estuarine food webs across latitudes in the Northeast United States. Environ Pollut 246:639-649. doi:10.1016/j.envpol.2018.12.064 PMID:30605819
  • Thomas DM, Lee C, Fisher NS. 2018. Bioaccumulation and trophic transfer of 137Cs in marine and freshwater plankton. Chemosphere 209:599-60729957520. doi:10.1016/j.chemosphere.2018.06.124 PMID:29957520



  • Baumann Z, Mason RP, Conover DO, Balcom PH, Chen CY, Buckman KL, Fisher NS, Baumann H. 2016. Mercury bioaccumulation increases with latitude in a coastal marine fish (Atlantic silverside Menidia menidia). Canadian Journal of Fisheries and Aquatic Sciences 74(7):1009-1015. doi:10.1139/cjfas-2016-0396 PMID:28701819 PMCID:PMC5502350
  • Gifford AH, Willger SD, Dolben E, Moulton LA, Dorman DB, Bean H, Hill J, Hampton TH, Ashare A, Hogan DA. 2016. Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung. Infect Immun 84(10):2995-3006. doi:10.1128/IAI.00437-16 PMID:27481238 PMCID:PMC5038062
  • Hogan DA, Willger SD, Dolben E, Hampton TH, Stanton BA, Morrison HG, Sogin ML, Czum J, Ashare A. 2016. Analysis of lung microbiota in bronchoalveolar lavage, protected brush and sputum samples from subjects with mild-to-moderate cystic fibrosis lung disease. PLoS One 11(3):e0149998. doi:10.1371/journal.pone.0149998 PMID:26943329 PMCID:PMC4778801
  • Koeppen K, Hampton TH, Jarek M, Scharfe M, Gerber SA, Mielcarz DW, Demers EG, Dolben E, Hammond JH, Hogan DA, Stanton BA. 2016. A novel mechanism of host-pathogen interaction through sRNA in bacterial outer membrane vesicles. PLoS Pathog 12(6):e1005672. doi:10.1371/journal.ppat.1005672 PMID:27295279 PMCID:PMC4905634





  • Chen CY, Dionne M, Mayes BM, Ward DM, Sturup S, Jackson BP. 2009. Mercury bioavailability and bioaccumulation in estuarine food webs in the Gulf of Maine. Environ Sci Technol 43(6):1804-1810. doi:10.1021/es8017122 PMID:19368175 PMCID:PMC2670462
  • Greene CS, Gilmore JM, Kiralis J, Andrews PC, Moore JH. 2009. Optimal use of expert knowledge in ant colony optimization for the analysis of epistasis in human disease. Lecture Notes in Computer Science 5483/2009:92-103. doi:10.1007/978-3-642-01184-9_9
  • Greene CS, Penrod NM, Kiralis J, Moore JH. 2009. Spatially uniform relieff (SURF) for computationally-efficient filtering of gene-gene interactions. BioData Min 2(1):5. doi:10.1186/1756-0381-2-5 PMID:19772641 PMCID:PMC2761303
  • Greene CS, Penrod NM, Williams SM, Moore JH. 2009. Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS One 4(6):e5639. doi:10.1371/journal.pone.0005639 PMID:19503614 PMCID:PMC2685469
  • Jackson BP, Taylor VF, Baker RA, Miller EK. 2009. Low-level mercury speciation in freshwaters by isotope dilution GC-ICP-MS. Environ Sci Technol 43(7):2463-9. doi:10.1021/es802656p PMID:19452902 PMCID:PMC2692077
  • Kozul-Horvath CD, Ely KH, Hamilton JW, Enelow RI. 2009. Low-dose arsenic compromises the immune response to influenza A infection in vivo. Environ Health Perspect 117(9):1441-1447. doi:10.1289/ehp.0900911 PMID:19750111 PMCID:PMC2737023
  • Kozul-Horvath CD, Hampton TH, Davey JC, Gosse JA, Nomikos AP, Eisenhauer PL, Weiss DJ, Thorpe JE, Ihnat MA, Hamilton JW. 2009. Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environ Health Perspect 117(7):1108-1115. doi:10.1289/ehp.0800199 PMID:19654921 PMCID:PMC2717138
  • Sinnott-Armstrong NA, Greene CS, Cancare F, Moore JH. 2009. Accelerating epistasis analysis in human genetics with consumer graphics hardware. BMC Res Notes 2:149. doi:10.1186/1756-0500-2-149 PMID:19630950 PMCID:PMC2732631
  • Ward DM, Nislow KH, Folt CL. 2009. Increased population density and suppressed prey biomass: relative impacts on juvenile Atlantic salmon growth. Trans Am Fish Soc 138(1):135-143. doi:10.1577/T08-128.1



  • Bodwell J, Gosse JA, Hamilton JW, Davey JC. 2007. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicol Sci 98(1):75-86. doi:10.1093/toxsci/kfm013 PMID:17283378


  • Bodwell J, Gosse JA, Nomikos AP, Hamilton JW. 2006. Arsenic disruption of steroid receptor gene activation: complex dose-response effects are shared by several steroid receptors. Chem Res Toxicol 19(12):1619-1629. doi:10.1021/tx060122q PMID:17173375 PMCID:PMC2556599
  • deLemos JL, Bostick BC, Renshaw CE, Sturup S, Feng X. 2006. Landfill-stimulated iron reduction and arsenic release at the Coakley Superfund site (NH). Environ Sci Technol 40(1):67-73. PMID:16433334
  • Fetalvero KM, Shyu M, Nomikos AP, Chiu YF, Wagner RJ, Powell RJ, Hwa J, Martin KA. 2006. The prostacyclin receptor induces human vascular smooth muscle cell differentiation via the protein kinase A pathway. Am J Physiol Heart Circ Physiol 290(4):H1337-46. PMID:16399867
  • Jackson BP, Seaman JC, Burger J, Punshon T, Adriano D. 2006. Arsenic and selenium speciation in aged flue gas desulfurization sludge amended soil. In: Coal Combustion Byproducts and Environmental Issues. Springer, New York, NY. pp.114-123.
  • Karimi R, Folt CL. 2006. Beyond macronutrients: element variability and multielement stoichiometry in freshwater invertebrates. Ecol Lett 9(12):1273-1283. doi:10.1111/j.1461-0248.2006.00979.x PMID:17118001
  • Punshon T, Lanzirotti A, Li L, Alonso JM, Ecker JR, Kaplan J, Guerinot ML, Kim SA. 2006. Localization of iron in Arabidopsis seed requires the vacuolar membrane transporter VIT1. Science 314(5803):1295-1298. doi:10.1126/science.1132563 PMID:17082420
  • Renshaw CE, Bostick BC, Feng X, Wong CK, Winston ES, Karimi R, Folt CL, Chen CY. 2006. Impact of land disturbance on the fate of arsenical pesticides. J Environ Qual 35(1):61-67. doi:10.2134/jeq2005.0096 PMID:16391277
  • Sajwan KS, Twardowska I, Alva AK, eds. 2006. Coal Combustion Byproducts and Environmental Issues. Springer, New York, NY.
  • Shaw JR, Dempsey TD, Chen CY, Hamilton JW, Folt CL. 2006. Comparative toxicity of cadmium, zinc, and mixtures of cadmium and zinc to daphnids. Environ Toxicol Chem 25(1):182-189. doi:10.1897/05-243R.1 PMID:16494240


  • Karagas MR, Park S, Warren AJ, Hamilton JW, Nelson HH, Mott LA, Kelsey KT. 2005. Gender, smoking, glutathione-S-transferase variants and bladder cancer incidence: a population-based study. Cancer Lett 219(1):63-69. doi:10.1016/j.canlet.2004.10.006 PMID:15694665
  • Perna L, LaCroix-Fralish A, Sturup S. 2005. Determination of inorganic mercury and methylmercury in zooplankton and fish samples by speciated isotopic dilution GC-ICP-MS after alkaline digestion. J Anal At Spectrom 20:236-238.
  • Pickhardt PC, Folt CL, Chen CY, Klaue B, Blum JD. 2005. Impacts of zooplankton composition and algal enrichment on the accumulation of mercury in an experimental freshwater food web. Sci Total Environ 339(1-3):89-101. doi:10.1016/j.scitotenv.2004.07.025 PMID:15740761
  • Spuches AM, Kruszyna HG, Rich AM, Wilcox DE. 2005. Thermodynamics of the As(III)-thiol interaction: arsenite and monomethylarsenite complexes with glutathione, dihydrolipoic acid, and other thiol ligands. Inorg Chem 44(8):2964-2972. PMID:15819584
  • Sturup S, Chen CY, Jukosky J, Folt CL. 2005. Isotope dilution quantification of 200Hg2+ and CH3 201Hg+ enriched species-specific tracers in aquatic systems by cold vapor ICPMS and algebraic de-convoluting. J Mass Spectrom 242(2-3):225-231.


  • Bodwell J, Kingsley LA, Hamilton JW. 2004. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chem Res Toxicol 17(8):1064-1076. PMID:15310238
  • Peters SC, Blum JD, Driscoll CT, Likens GE. 2004. Dissolution of wollastonite during the experimental manipulation of Hubbard Brook Watershed 1. Biogeochemistry 67(3):309-329. doi:10.1023/B:BIOG.0000015787.44175.3f
  • Wickre JB, Folt CL, Sturup S, Karagas MR. 2004. Environmental exposure and fingernail analysis of arsenic and mercury in children and adults in a Nicaraguan gold mining community. Arch Environ Health 59(8):400-409. PMID:16268116


  • Birge WJ, Price DJ, Shaw JR, Stromberg JA, Wigginton AJ, Hogstrand C. 2003. Metal body burden and biological sensors as ecological indicators. In: Silver: Environmental Transport, Fate, Effects, and Models. SETAC Press, Pensacola, FL.
  • Chung MC, Gu XH, Etzenhouser BA, Spuches AM, Rye PT, Seetharaman SK, Rose DJ, Zubieta J, Sponsler MB. 2003. Intermetal coupling in [(eta(5)-C5R5)Fe(dppe)](2)(mu-CH=CHCH=CH) and in their dicationic and monocationic mixed-valence forms. Organometallics 22(17):3485-3494.
  • Perna L, Jernstrom J, Aldave de las Heras L, de Pablo J, Betti M. 2003. Sample cleanup by on-line chromatography for the determination of Am in sediments and soils by -spectrometry. Anal Chem 75(10):2292-2298. PMID:12918969
  • Perna L, Jernstrom J, Aldave de las Heras L, Hrnecek E, Betti M. 2003. Characterization of radioactively cotaminated marine sediment core by radiometric and mass spectrometric techniques. In: Proceedings of the International Conference on Methods and applications of radioanalytical chemistry MARC (METHODS AND APPLICATIONS OF RADIOANALYTICAL CHEMISTRY) VI, 7-11 April. Kailuakona, HI.
  • Perna L, Jernstrom J, Aldave de las Heras L, Hrnecek E, de Pablo J, Betti M. 2003. Characterization of radioactively contaminated marine sediment core by radiometric and mass spectrometric techniques. Journal of Radioanalytical and Nuclear Chemistry
  • Shaw JR, Wood CM, Birge WJ, Hogstrand C. 2003. Toxicity of silver to the marine telost, (Oligocottus maculosus): Effects of slinity and ammonia. In: Silver: Environmental Transport, Fate, Effects, and Models. SETAC Press, Pensacola, FL. pp.441.
  • Soucy NV, Ihnat MA, Kamat CD, Hess L, Post MJ, Klei L, Clark C, Barchowsky A. 2003. Arsenic stimulates angiogenesis and tumorigenesis in vivo. Toxicol Sci 76(2):271-279. doi:10.1093/toxsci/kfg231 PMID:12970581


  • Andrew AS, Klei LR, Barchowsky A. 2001. AP-1-dependent induction of plasminogen activator inhibitor-1 by nickel does not require reactive oxygen. Am J Physiol 281(3):L616-L623. PMID:11504688
  • Andrew AS, Klei LR, Barchowsky A. 2001. Nickel requires hypoxia inducible factor-1a, not redox signaling to induce plasminogen activator inhibitor-1. Am J Physiol 281(3):L607-L615. PMID:11504687
  • Andrew AS, Klei LR, Barchowsky A. 2001. Role of oxidative, AP-1, and hypoxia-responsive signaling pathways in induction of plasminogen activator inhibitor-1 (PAI-1) by nickel. Environ Health Perspect 60:212.
  • Kaltreider RC, Davis AM, Lariviere JP, Hamilton JW. 2001. Arsenic alters the function of the glucocorticoid receptor as a transcription factor. Environ Health Perspect 109(3):245-251. PMID:11333185
  • Karagas MR, Stukel TA, Morris J, Tosteson TD, Spencer SK, Greenberg ER. 2001. Skin cancer risk in relation to toenail arsenic concentrations in a US population-based case-control study. Am J Epidemiol 153(6):559-565. PMID:11257063
  • Soucy NV, Andrew AS, Barchowsky A. 2001. Nickel induces IL-8 expression in human airway epithelial cells. Environ Health Perspect 60:317.
  • Soucy NV, Klei LR, Barchowsky A. 2001. Mechanisms for arsenite-stimulated vascular cell angiogenic and profibrotic gene expression. Free Radic Biol Med 31:S62.


  • Andrew AS, Barchowsky A. 2000. Nickel-induced plasminogen activator inhibitor-1 expression inhibits the fibrinolytic activity of human airway epithelial cells. Toxicol Appl Pharmacol 168(1):50-57. PMID:11000099
  • Andrew AS, Klei LR, Barchowsky A. 2000. Role of oxidative, AP-1, and hypoxia-responsive signaling pathways in induction of plasminogen activator inhibitor-1 (PAI-1) by nickel. Free Radic Biol Med 29:S53.
  • Hamilton JW, Kaltreider RC, Davis AM, Green RA. 2000. Arsenic(III) and chromium(VI) alter glucocorticoid receptor (GR) function and GR-dependent gene regulation. Metal Ions in Biology and Medicine 6:66-68.
  • Karagas MR, Tosteson TD, Blum JD, Klaue B, Weiss JE, Stannard V, Spate VL, Morris J. 2000. Measurement of low levels of arsenic exposure: a comparison of water and toenail concentrations. Am J Epidemiol 152(1):84-90. PMID:10901333
  • Klaue B, Kesler SE, Blum JD. 2000. Investigation of natural fractionation of stable mercury isotopes by multi-collector inductively coupled plasma mass spectrometry. In: Proceedings of the International Conference on Heavy Metals in the Environment. Ann Arbor, MI. pp.1101.
  • Peters SC, Blum JD. 2000. Arsenic in groundwater systems of New Hampshire. In: Proceedings of the International Conference on Heavy Metals in the Environment. Ann Arbor, MI. pp.1338.
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