Superfund Research Program
Inhalation Toxicology Core
Project Leader: Alexandra Noel
Co-Investigator: Arthur Penn
Grant Number: P42ES013648
Funding Period: 2020-2025
Project-Specific Links
- Project Summary
Publications
2024
- Aryal A, Harmon AC, Varner K, Noël A, Cormier SA, Nde D, Mottram P, Maxie J, Dugas TR. 2024. Inhalation of particulate matter containing environmentally persistent free radicals induces endothelial dysfunction mediated via AhR activation at the air-blood interface. Toxicol Sci doi:10.1093/toxsci/kfae007 PMID:38310335
2023
- Aryal A, Noel A, Khachatryan L, Cormier SA, Chowdhury PH, Penn A, Dugas TR, Harmon AC. 2023. Environmentally persistent free radicals: Methods for combustion generation, whole-body inhalation and assessing cardiopulmonary consequences. Environ Pollut 334:122183. doi:10.1016/j.envpol.2023.122183 PMID:37442324
- Noël A, Harmon AC, Subramanian B, Perveen Z, Aryal A, Legendre K, Zaman H, Paulsen DB, Varner KJ, Dugas TR, Penn A. 2023. Adjuvant effect of inhaled particulate matter containing free radicals following house-dust mite induction of asthma in mice. Inhal Toxicol 35:333-349. doi:10.1080/08958378.2023.2289024 PMID:38060410 PMCID:10903547
2022
- Noel A, Ashbrook DG, Xu F, Cormier SA, Lu L, O'Callaghan JP, Menon SK, Zhao W, Penn A, Jones BC. 2022. Genomic basis for individual differences in susceptibility to the neurotoxic effects of diesel exhaust. Int J Mol Sci 23(20):12461. doi:10.3390/ijms232012461 PMID:36293318 PMCID:PMC9603950
2021
- Harmon AC, Noel A, Subramanian B, Perveen Z, Jennings MH, Chen Y, Penn A, Legendre K, Paulsen DB, Varner KJ, Dugas TR. 2021. Inhalation of particulate matter containing free radicals leads to decreased vascular responsiveness associated with an altered pulmonary function. Am J Physiol Heart Circ Physiol 321(4):H667-H683. doi:10.1152/ajpheart.00725.2020 PMID:34415187