Superfund Research Program

Materials Core

Project Leader: Lavrent Khachatryan
Co-Investigator: Slawomir Lomnicki
Grant Number: P42ES013648
Funding Period: 2011-2025

Project-Specific Links

Publications

2023

• Aryal A, Noel A, Khachatryan L, Cormier SA, Chowdhury PH, Penn A, Dugas TR, Harmon AC. 2023. Environmentally persistent free radicals: Methods for combustion generation, whole-body inhalation and assessing cardiopulmonary consequences. Environ Pollut 334:122183. doi:10.1016/j.envpol.2023.122183 PMID:37442324
• Yamamoto A, Sly PD, Chew KY, Khachatryan L, Begum N, Yeo AJ, Vu LD, Short KR, Cormier SA, Fantino E. 2023. Environmentally persistent free radicals enhance SARS-CoV-2 replication in respiratory epithelium. Exp Biol Med (Maywood) doi:10.1177/15353702221142616 PMID:36628928 PMCID:PMC9836833

2022

• Khachatryan L, Barekati-Goudarzi M, Asatryan R, Ozarowski A, Boldor D, Lomnicki S, Cormier SA. 2022. Metal-free Biomass-Derived Environmentally Persistent Free Radicals (Bio-EPFRs) from lignin pyrolysis. ACS Omega 7(34):30241-30249. doi:10.1021/acsomega.2c03381 PMID:36061701 PMCID:PMC9434622

2017

• Feld-Cook EE, Bovenkamp-Langlois L, Lomnicki S. 2017. Effect of particulate matter mineral composition on Environmentally Persistent Free Radical (EPFR) formation. Environ Sci Technol 51(18):10396-10402. doi:10.1021/acs.est.7b01521 PMID:28817261 PMCID:PMC5778880
• Nganai S, Lomnicki S. 2017. Surface catalysed PCDD/F formation from precursors - high PCDF yield does not indicate de novo mechanism!. Int. J. Environ Pollution 61(3-4):208-222. doi:10.1504/IJEP.2017.10008687 PMID:30147247 PMCID:PMC6107310
• Oyana T, Lomnicki S, Guo C, Cormier SA. 2017. A scalable field study protocol and rationale for passive ambient air sampling: a spatial phytosampling for leaf data collection. Environ Sci Technol 51(18):10663-10673. doi:10.1021/acs.est.7b03643 PMID:28805054

2016

• Dugas TR, Lomnicki S, Cormier SA, Dellinger B, Reams MA. 2016. Addressing emerging risks: scientific and regulatory challenges associated with environmentally persistent free radicals. Int J Environ Res Public Health 13(6):573. doi:10.3390/ijerph13060573 PMID:27338429 PMCID:PMC4924030
• Potter PM, Dellinger B, Lomnicki S. 2016. Contribution of aluminas and aluminosilicates to the formation of PCDD/Fs on fly ashes. Chemosphere 144:2421-2426. doi:10.1016/j.chemosphere.2015.11.009 PMID:26615490 PMCID:PMC4695248

2015

• Jaligama S, Chen Z, Saravia J, Yadav N, Lomnicki S, Dugas TR, Cormier SA. 2015. Exposure to deepwater horizon crude oil burnoff particulate matter induces pulmonary inflammation and alters adaptive immune response. Environ Sci Technol 49(14):8769-8776. doi:10.1021/acs.est.5b01439 PMID:26115348 PMCID:PMC4526136
• Reed JR, dela Cruz AL, Lomnicki S, Backes WL. 2015. Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2. Toxicol Appl Pharmacol 289(2):223-230. doi:10.1016/j.taap.2015.09.021 PMID:26423927 PMCID:PMC4651829
• Reed JR, dela Cruz AL, Lomnicki S, Backes WL. 2015. Inhibition of cytochrome P450 2B4 by environmentally persistent free radical-containing particulate matter. Biochem Pharmacol 95(2):126-132. doi:10.1016/j.bcp.2015.03.012 PMID:25817938 PMCID:PMC4406862
• Thibodeaux CA, Poliakoff ED, Kizilkaya O, Patterson MC, DiTusa MF, Kurtz RL, Sprunger PT. 2015. Probing environmentally significant surface radicals: crystallographic and temperature dependent adsorption of phenol on ZnO. Chem Phys Lett 638:56-60. doi:10.1016/j.cplett.2015.08.026 PMID:26388650 PMCID:PMC4570833

2014

• Kiruri LW, Khachatryan L, Dellinger B, Lomnicki S. 2014. Effect of copper oxide concentration on the formation and persistency of environmentally persistent free radicals (EPFRs) in particulates. Environ Sci Technol 48(4):2212-2217. doi:10.1021/es404013g PMID:24437381 PMCID:PMC3983329
• Nganai S, Dellinger B, Lomnicki S. 2014. PCDD/PCDF ratio in the precursor formation model over CuO surface. Environ Sci Technol 48(23):13864-13870. doi:10.1021/es504253w PMID:25372621 PMCID:PMC4255659
• Reed JR, Cawley GF, Ardoin TG, Dellinger B, Lomnicki S, Kiruri LW, Backes WL. 2014. Environmentally persistent free radicals inhibit cytochrome P450 activity in rat liver microsomes. Toxicol Appl Pharmacol 277(2):200-209. doi:10.1016/j.taap.2014.03.021 PMID:24713513 PMCID:PMC4049543
• Saravia J, You D, Thevenot PT, Lee GI, Shrestha B, Lomnicki S, Cormier SA. 2014. Early-life exposure to combustion-derived particulate matter causes pulmonary immunosuppression. Mucosal Immunol 7(3):694-704. doi:10.1038/mi.2013.88 PMID:24172848 PMCID:PMC3999175

2013

• Herring M, Khachatryan L, Lomnicki S, Dellinger B. 2013. Paramagnetic centers in particulate formed from the oxidative pyrolysis of 1-methylnaphthalene in the presence of Fe(lll)₂0₃ nanoparticles. Combustion and Flame 160(12):2996-3003. doi:10.1016/j.combustflame.2013.06.025 PMID:25673882 PMCID:PMC4321761
• Herring M, Potter PM, Wu H, Lomnicki S, Dellinger B. 2013. Fe₂O₃ nanoparticle mediated molecular growth and soot inception from the oxidative pyrolysis of 1-methylnaphthalene. Proc Combust Inst 34(1):1749-1757. doi:10.1016/j.proci.2012.07.057 PMID:25530732 PMCID:PMC4269167
• Kiruri LW, Dellinger B, Lomnicki S. 2013. Tar balls from Deep Water Horizon Oil Spill: environmentally persistent free radicals (EPFR) formation during crude weathering. Environ Sci Technol 47(9):4220-4226. doi:10.1021/es305157w PMID:23510127 PMCID:PMC4267227
• Patterson MC, Keilbart ND, Kiruri LW, Thibodeaux CA, Lomnicki S, Kurtz RL, Poliakoff ED, Dellinger B, Sprunger PT. 2013. EPFR formation from phenol adsorption on Al₂O₃ and TiO₂: EPR and EELS studies. Chem Phys 422:277-282. doi:10.1016/j.chemphys.2012.12.003 PMID:24443627 PMCID:PMC3891583
• Saravia J, Lee GI, Lomnicki S, Dellinger B, Cormier SA. 2013. Particulate matter containing environmentally persistent free radicals and adverse infant respiratory health effects: A review. J Biochem Mol Toxicol 27(1):56-68. doi:10.1002/jbt.21465 PMID:23281110 PMCID:PMC3580159
• Thevenot PT, Saravia J, Jin N, Giaimo JD, Chustz RE, Mahne S, Kelley MA, Hebert VY, Dellinger B, Dugas TR, DeMayo FJ, Cormier SA. 2013. Radical-containing ultrafine particulate matter initiates epithelial-to-mesenchymal transitions in airway epithelial cells. Am J Respir Cell Mol Biol 48(2):188-197. doi:10.1165/rcmb.2012-0052OC PMID:23087054 PMCID:PMC3604062

2011

• dela Cruz AL, Gehling W, Lomnicki S, Cook RL, Dellinger B. 2011. Detection of environmentally persistent free radicals at a superfund wood treating site. Environ Sci Technol 45(15):6356–6365. doi:10.1021/es2012947 PMID:21732664 PMCID:PMC3167238 (Completed with ARRA Funds)
• Khachatryan L, Vejerano E, Lomnicki S, Dellinger B. 2011. Environmentally persistent free radicals (EPFRs). 1. Generation of reactive oxygen species in aqueous solutions. Environ Sci Technol 45:8559-8566. doi:10.1021/es201309c PMID:21823585 PMCID:PMC3230252 (Completed with ARRA Funds)
• Lord K, Moll D, Lindsey JK, Mahne S, Raman G, Dugas TR, Cormier SA, Troxlair D, Lomnicki S, Dellinger B, Varner KJ. 2011. Environmentally persistent free radicals decrease cardiac function before and after ischemia/reperfusion injury in vivo. J Recept Signal Transduct Res 31(2):157-167. doi:10.3109/10799893.2011.555767 PMID:21385100 PMCID:PMC3152960 (Completed with ARRA Funds)
• Nganai S, Lomnicki S, Dellinger B. 2011. Formation of PCDD/Fs from the copper oxide-mediated pyrolysis and oxidation of 1,2-dichlorobenzene. Environ Sci Technol 45(3):1034-1040. doi:10.1021/es102948f PMID:21174454
• Vejerano E, Lomnicki S, Dellinger B. 2011. Formation and stabilization of combustion-generated environmentally persistent free radicals on an Fe(lll)(2)0-3/silica surface. Environ Sci Technol 45(2):589-94. doi:10.1021/es102841s PMID:21138295