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Your Environment. Your Health.

Project Publications: University of Pennsylvania: Inter-disciplinary Training Core

Superfund Research Program

Inter-disciplinary Training Core

Project Leader: Trevor M. Penning
Co-Investigator: Reto Giere
Grant Number: P42ES023720
Funding Period: 2014-2020
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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  • Chatterjee S, Pietrofesa RA, Park K, Tao J, Carabe-Fernandez A, Berman A, Koumenis C, Sielecki T, Christofidou-Solomidou M. 2019. LGM2605 reduces space radiation-induced NLRP3 inflammasome activation and damage in in vitro lung vascular networks. Int J Mol Sci 20(1):176. doi:10.3390/ijms20010176 PMID:30621290 PMCID:PMC6337675
  • Zhu B, Suzuki Y, DiSanto T, Rubin S, Penfil Z, Pietrofesa RA, Chatterjee S, Christofidou-Solomidou M, Cantu E. 2019. Applications of out of body lung perfusion. Acad Radiol 26(3):404-411. doi:10.1016/j.acra.2018.05.022 PMID:30054193 PMCID:PMC6345618


  • Arletti R, Fantini R, Giacobbe C, Giere R, Vezzalini G, Vigliaturo R, Quartieri S. 2018. High-temperature behavior of natural ferrierite: In-situ synchrotron X-ray powder diffraction study. American Mineralogist 103:1741-1748. doi:10.2138/am-2018-6663
  • Chikara S, Mamidi S, Sreedasyam A, Pietrofesa RA, Zuppa A, Moorthy G, Dyer N, Christofidou-Solomidou M, Reindl KM. 2018. Flaxseed consumption inhibits chemically induced lung tumorigenesis and modulates expression of phase II enzymes and inflammatory cytokines in A/J mice. Cancer Prev Res (Phila) 11(1):27-37. doi:10.1158/1940-6207.CAPR-17-0119 PMID:29074535 PMCID:PMC5754250
  • Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Mesaros C, Lynch DR, Blair IA. 2018. Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes. Sci Rep 8(1):17043. doi:10.1038/s41598-018-35346-y PMID:30451920 PMCID:PMC6242848
  • Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA. 2018. Liquid chromatography-high resolution mass spectrometry analysis of platelet frataxin as a protein biomarker for the rare disease Friedreich's ataxia. Anal Chem 90:2216-2223. doi:10.1021/acs.analchem.7b04590 PMID:29272104 PMCID:PMC5817373
  • Mazaleuskaya LL, Salamatipour A, Sarantopoulou D, Weng L, FitzGerald GA, Blair IA, Mesaros C. 2018. Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS. J Lipid Res 59:564-575. doi:10.1194/jlr.D081414 PMID:29301865 PMCID:PMC5832923
  • Mishra OP, Popov AV, Pietrofesa RA, Andrake M, Nakamaru-Ogiso E, Christofidou-Solomidou M. 2018. Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochim Biophys Acta 1862(6):1364-1375. doi:10.1016/j.bbagen.2018.03.003 PMID:29524540
  • Mohanty SK, Gonneau C, Salamatipour A, Pietrofesa RA, Casper BB, Christofidou-Solomidou M, Willenbring JK. 2018. Siderophore-mediated iron removal from chrysotile: implications for asbestos toxicity reduction and bioremediation. J Hazard Mater 341:290-296. doi:10.1016/j.jhazmat.2017.07.033 PMID:28797944 PMCID:PMC5771417
  • Pietrofesa RA, Chatterjee S, Park K, Arguiri E, Albelda SM, Christofidou-Solomidou M. 2018. Synthetic lignan secoisolariciresinol diglucoside (LGM2605) reduces asbestos-induced inflammation and inflammasome activation in mice in an Nrf2-dependent and independent manner. Antioxidants (Basel) 7(3):38. doi:10.3390/antiox7030038 PMID:29498660 PMCID:PMC5874524
  • Ventura GD, Vigliaturo R, Giere R, Pollastri S, Gualtieri AF, Iezzi G. 2018. Infra red spectroscopy of the regulated asbestos amphiboles. Minerals 8(9):413. doi:10.3390/min8090413
  • Vigliaturo R, Ventura GD, Choi JK, Marengo A, Lucci F, O'Shea M, Perez-Rodriguez I, Giere R. 2018. Mineralogical characterization and dissolution experiments in Gamble's solution of Tremolitic Amphibole from Passo di Caldenno (Sondrio, Italy). Minerals 8:24. doi:10.3390/min8120557
  • Weng L, Guo L, Vachani A, Mesaros C, Blair IA. 2018. Quantification of serum high mobility group box 1 by liquid chromatography/high-resolution mass spectrometry: Implications for its role in immunity, inflammation, and cancer. Anal Chem 90:7552-7560. doi:10.1021/acs.analchem.8b01175 PMID:29791130
  • Xu R, Barg FK, Emmett EA, Wiebe D, Hwang W. 2018. Association between mesothelioma and non-occupational asbestos exposure: systematic review and meta-analysis. Environ Health 17(1):90. doi:10.1186/s12940-018-0431-9 PMID:30567579 PMCID:PMC6300000


  • Cheung M, Menges CW, Testa JR. 2017. Germline and Somatic Mutations in Human Mesothelioma and Lessons from Asbestos-Exposed Genetically Engineered Mouse Models. Chapter 8 in: Asbestos and Mesothelioma. Springer International Publishing, pp.175-195.
  • Cheung M, Testa JR. 2017. BAP1, a tumor suppressor gene driving malignant mesothelioma. Transl Lung Cancer Res 6(3):270-278. doi:10.21037/tlcr.2017.05.03 PMID:28713672 PMCID:PMC5504107
  • Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Koumenis C, Segal R. 2017. Radiation mitigating properties of intranasally administered KL4 surfactant in a murine model of radiation-induced lung damage. Radiation Research 188(5):491-504. doi:10.1667/RR14686.1 PMID:28877030 PMCID:PMC5704933
  • Dietterich LH, Gonneau C, Casper BB. 2017. Arbuscular mycorrhizal colonization has little consequence for plant heavy metal uptake in contaminated field soils. Ecol Appl 27(6):1862-1875. doi:10.1002/eap.1573 PMID:28482132 PMCID:PMC5581990
  • Ferdowsi B, Ortiz C, Houssais M, Jerolmack DJ. 2017. River-bed armouring as a granular segregation phenomenon. Nat Commun 8(1):1363. doi:10.1038/s41467-017-01681-3 PMID:29118422 PMCID:PMC5678076
  • Gonneau C, Miller K, Mohanty SK, Xu R, Hwang W, Willenbring JK, Casper BB. 2017. Framework for assessment and phytoremediation of asbestos-contaminated sites. Environ Sci Pollut Res Int 24:25912-25922. doi:10.1007/s11356-017-0177-x PMID:28940054
  • Gonneau C, Mohanty SK, Dietterich LH, Hwang W, Willenbring JK, Casper BB. 2017. Differential elemental uptake in three pseudo-metallophyte C4 grasses in situ in the eastern USA. Plant Soil 416:149-163. doi:10.1007/s11104-017-3198-9 PMID:28845059 PMCID:PMC5568086
  • Hinderer C, Katz N, Louboutin J, Bell P, Tolar J, Orchard PJ, Lund TC, Nayal M, Weng L, Mesaros C, de Souza CF, Corte AD, Giugliani R, Wilson JM. 2017. Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis. Hum Mol Genet 26(19):3837-3849. doi:10.1093/hmg/ddx277 PMID:28934395 PMCID:PMC5886077
  • Mesaros C, Blair IA, Weng L. 2017. Biomarkers of response to asbestos exposure. Chapter 12 in: Asbestos and Mesothelioma. Springer International Publishing, pp.259-277.
  • Pietrofesa RA, Woodruff P, Hwang W, Patel P, Chatterjee S, Albelda SM, Christofidou-Solomidou M. 2017. The synthetic lignan secoisolariciresinol diglucoside prevents asbestos-induced NLRP3 inflammasome activation in murine macrophages. Oxid Med Cell Longev 2017:739523. doi:10.1155/2017/7395238 PMID:29075366 PMCID:PMC5615985
  • Velalopoulou A, Chatterjee S, Pietrofesa RA, Koziol-White C, Panettieri RA, Lin L, Tuttle S, Berman A, Koumenis C, Christofidou-Solomidou M. 2017. Synthetic secoisolariciresinol diglucoside (LGM2605) protects human lung in an ex vivo model of proton radiation damage. Int J Mol Sci 18(12):E2525. doi:10.3390/ijms18122525 PMID:29186841 PMCID:PMC5751128
  • Wu L, Ortiz C, Jerolmack DJ. 2017. Aggregation of elongated colloids in water. Langmuir 33(2):622-629. doi:10.1021/acs.langmuir.6b03962 PMID:27931099 PMCID:PMC5283798
  • Xu R, Mesaros C, Weng L, Snyder NW, Vachani A, Blair IA, Hwang W. 2017. Comparison of statistical methods for detection of serum lipid biomarkers for mesothelioma and asbestos exposure. Biomark Med 11:547-556. doi:10.2217/bmm-2017-0087 PMID:28534416 PMCID:PMC5619144


  • Vazquez-Medina J, Dodia C, Weng L, Mesaros C, Blair IA, Feinstein SI, Chatterjee S, Fisher AB. 2016. The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages. FASEB J 30(8):2885-2898. doi:10.1096/fj.201500146R PMID:27178323 PMCID:PMC4970605
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