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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Program Publications: University of Rhode Island: Sources, Transport, Exposure & Effects of PFAS (STEEP) Center

Superfund Research Program

Sources, Transport, Exposure & Effects of PFAS (STEEP) Center

Center Director: Rainer Lohmann
Grant Number: P42ES027706
Funding Period: 2017-2027
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Publications

  • Sunderland EM, Wagner CC. The global chemical experiment. In: Earth 2020: An insider's guide to a rapidly changing planet.

2024

  • Alesio J, Bothun GD. 2024. Differential scanning fluorimetry to assess PFAS binding to bovine serum albumin protein. Sci Rep 14(1):6501. doi:10.1038/s41598-024-57140-9 PMID:38499613
  • Andersen HR, Grandjean P, Main K, Jensen TK, Nielsen F. 2024. Higher serum concentrations of PFAS among pesticide exposed female greenhouse workers. Int J Hyg Environ Health 255:doi:10.1016/j.ijheh.2023.114292 PMID:37952389
  • Dunn M, Noons N, Vojta S, Becanova J, Pickard HM, Sunderland E, Lohmann R. 2024. Unregulated active and closed textile mills represent a significant vector of PFAS contamination into coastal rivers. ACS ES&T Wat 4(1):114-124. doi:10.1021/acsestwater.3c00439 PMID:38222965 PMCID:PMC10785679
  • Dunn M, Vojta S, Soltwedel T, von Appen W, Lohmann R. 2024. Passive sampler derived profiles and mass flows of perfluorinated alkyl substances (PFASs) across the Fram Strait in the North Atlantic. Environ Sci Technol Lett 11(2):166-171. doi:10.1021/acs.estlett.3c00835 PMID:38405271 PMCID:10883200
  • Fischer F, Ludtke S, Thackray CP, Pickard HM, Haque F, Dassuncao C, Endo S, Schaider L, Sunderland EM. 2024. Binding of per- and polyfluoroalkyl substances (PFAS) to serum proteins: Implications for toxicokinetics in humans. Environ Sci Technol 58(2):1055-1063. doi:10.1021/acs.est.3c07415 PMID:38166384
  • Hmila I, Hill J, Shalaby K, Ouararhni K, Abedsselem H, Modaresi SM, Bihaqi SW, Marques E, Sondhi A, Slitt AL, Zawia N. 2024. Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development. Ecotoxicol Environ Saf 272:doi:10.1016/j.ecoenv.2024.116070
  • Nielsen F, Fischer FC, Leth P, Grandjean P. 2024. Occurrence of major perfluorinated alkylate substances in human blood and target organs. Environ Sci Technol 58(1):143-149. doi:10.1021/acs.est.3c06499 PMID:38154793 PMCID:10785751
  • Pickard HM, Haque F, Sunderland EM. 2024. Bioaccumulation of perfluoroalkyl sulfonamides (FASA). Environ Sci Technol Lett doi:10.1021/acs.estlett.4c00143
  • Sigvaldsen A, Højsager F, Paarup H, Beck I, Timmermann CA, Boye H, Nielsen F, Halldorsson T, Nielsen C, Möller S, Barington T, Grandjean P, Jensen TK. 2024. Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child Cohort. Environ Res 242:117814. doi:10.1016/j.envres.2023.117814 PMID:38042520

2023

  • Agerstrand M, Arinaitwe K, Backhaus T, Barra RO, Diamond ML, Grimalt JO, Groh K, Kandie F, Kurt-Karakus PB, Letcher RJ, Lohmann R, Meire RO, Oluseyi T, Schaffer A, Septiono M, Sigmund G, Soehl A, Sogbanmu TO, Suzuki N, Venier M, Vlahos P, Scheringer M. 2023. Key principles for the intergovernmental science-policy panel on chemicals and waste. Environ Sci Technol 57(6):2205-2208. doi:10.1021/acs.est.2c08283 PMID:36716264 PMCID:PMC9933528
  • Barber LB, Pickard HM, Alvarez DA, Becanova J, Keefe SH, LeBlanc DR, Lohmann R, Steevens JA, Vajda A. 2023. Uptake of per- and polyfluoroalkyl substances by fish, mussel, and passive samplers in mobile-laboratory exposures using groundwater from a contamination plume at a historical fire training area, Cape Cod, Massachusetts. Environ Sci Technol 57(14):5544-5557. doi:10.1021/acs.est.2c06500 PMID:36972291 PMCID:PMC1011619
  • Baumert BO, Fischer FC, Nielsen F, Grandjean P, Bartell SM, Stratakis N, Walker DI, Valvi D, Kohli R, Inge T, Ryder J, Jenkins T, Sisley S, Xanthakos S, Rock S, La Merrill MA, Conti D, McConnell R, Chatzi L. 2023. Paired liver:plasma PFAS concentration ratios from adolescents in the Teen-LABS Study and derivation of empirical and mass balance models to predict and explain liver PFAS accumulation. Environ Sci Technol 57(40):14817-14826. doi:10.1021/acs.est.3c02765 PMID:37756184 PMCID:PMC10591710
  • Crisalli AM, Cai A, Cho BP. 2023. Probing the interactions of perfluorocarboxylic acids of various chain lengths with human serum albumin: calorimetric and spectroscopic investigations. Chem Res Toxicol 36(4):703-713. doi:10.1021/acs.chemrestox.3c00011 PMID:37001030
  • Dunn M, Becanova J, Snook J, Ruyle BJ, Lohmann R. 2023. Calibration of perfluorinated alkyl acid uptake rates by an tube passive sampler in water. ACS ES&T Wat 3(2):332-341. doi:10.1021/acsestwater.2c00384
  • Grandjean P, Meddis A, Nielsen F, Beck IH, Bilenberg N, Goodman C, Hu H, Till C, Budtz-Jorgensen E. 2023. Dose dependence of prenatal fluoride exposure associations with cognitive performance at school age in three prospective studies. Eur J Public Health doi:10.1093/eurpub/ckad170 PMID:37798092
  • Grandjean P, Meddis A, Nielsen F, Sjodin A, Hjorth MF, Astrup A, Budtz-Jorgensen E. 2023. Weight loss relapse associated with exposure to perfluoroalkylate substances. Obesity (Silver Spring) doi:10.1002/oby.23755 PMID:37069729 PMCID:PMC5810983
  • Liddie J, Schaider L, Sunderland EM. 2023. Sociodemographic factors are associated with the abundance of PFAS sources and detection in U.S. community water systems. Environ Sci Technol 57(21):7902-7912. doi:10.1021/acs.est.2c07255 PMID:37184106 PMCID:PMC10233791
  • Lohmann R, Letcher RJ. 2023. The universe of fluorinated polymers and polymeric substances and potential environmental impacts and concerns. Curr Opin Green Sustain Chem 41:100795. doi:10.1016/j.cogsc.2023.100795 PMID:37009204 PMCID:PMC1006224
  • Ruyle BJ, Pickard HM, Schultes L, Fredriksson F, Heffernan AL, Knappe D, Lord HL, Meng P, Mills MA, Ndunga K, Roesch P, Rundberget JT, Tettenhorst DR, Van Buren J, Vogel C, Westerman DC, Yeung LW, Sunderland EM. 2023. Interlaboratory comparison of extractable organofluorine measurements in groundwater and eel (Anguilla rostrata): recommendations for methods standardization. Environ Sci Technol 57(48):20159-20168. doi:10.1021/acs.est.3c04560 PMID:37934924 PMCID:PMC10702518
  • Ruyle BJ, Schultes L, Akob DM, Harris CR, Lorah M, Vojta S, Becanova J, McCann S, Pickard HM, Pearson A, Lohmann R, Vecitis CD, Sunderland E. 2023. Nitrifying microorganisms linked to biotransformation of perfluoroalkyl sulfonamido precursors from legacy aqueous film-forming foams. Environ Sci Technol 57(14):5592-5602. doi:10.1021/acs.est.2c07178 PMID:36972708 PMCID:PMC1010054
  • Ruyle BJ, Thackray CP, Butt CM, LeBlanc DR, Tokranov AK, Vecitis CD, Sunderland EM. 2023. Centurial persistence for forever chemicals at military fire training sites. Environ Sci Technol 57(21):8096-8106. doi:10.1021/acs.est.3c00675 PMID:37184088 PMCID:PMC10233753
  • Snook J, Becanova J, Vojta S, Lohmann R. 2023. Avoiding artifacts in the determination of per- and polyfluoroalkyl substance sorbent-water distribution. ACS ES&T Wat 3(8):2355-2362. doi:10.1021/acsestwater.3c00084
  • Valvi D, Christiani DC, Coull BA, Hojlund K, Nielsen F, Audouze K, Su L, Grandjean P. 2023. Gene-environment interactions in the associations of PFAS exposure with insulin sensitivity and beta-cell function in a Faroese cohort followed from birth to adulthood. Environ Res 226:115600. doi:10.1016/j.envres.2023.115600 PMID:36868448 PMCID:PMC1010192
  • Zhang Y, Mustieles V, Wang Y, Sun Q, Coull BA, Sun Y, Slitt AL, Messerlian C. 2023. Red blood cell folate modifies the association between serum per- and polyfluoroalkyl substances and antibody concentrations in U.S. adolescents. Environ Sci Technol 57(6):2445-2456. doi:10.1021/acs.est.2c07152 PMID:36715557

2022

  • Blomberg AJ, Mortensen J, Weihe P, Grandjean P. 2022. Bone mass density following developmental exposures to perfluoroalkyl substances (PFAS): a longitudinal cohort study. Environmental Health 21(1):113. doi:10.1186/s12940-022-00929-w PMID:36402982 PMCID:PMC9675242
  • Gardiner C, Robuck AR, Becanova J, Cantwell MG, Kaserzon S, Katz D, Mueller JF, Lohmann R. 2022. Field validation of a novel passive sampler for dissolved PFAS in surface waters. Environ Toxicol Chem doi:10.1002/etc.5431 PMID:35833595
  • Gluge J, London R, Cousins IT, DeWitt JC, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Trier X, Wang Z, Scheringer M. 2022. Information requirements under the essential-use concept: PFAS case studies. Environ Sci Technol doi:10.1021/acs.est.1c03732 PMID:34608797 PMCID:PMC8980108
  • Lochhead P, Khalili H, Ananthakrishnan AN, Burke KE, Richter JM, Sun Q, Grandjean P, Chan AT. 2022. Plasma concentrations of perfluoroalkyl substances and risk of inflammatory bowel diseases in women: a nested case control analysis in the Nurses' Health Study cohorts. Environ Res 207:112222. doi:10.1016/j.envres.2021.112222 PMID:34662575
  • Marques E, Pfohl M, Wei W, Tarantola G, Ford L, Amaeze O, Alesio J, Ryu S, Jia X, Zhu H, Bothun GD, Slitt AL. 2022. Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes. Toxicol Appl Pharmacol 442:115991. doi:10.1016/j.taap.2022.115991 PMID:35337807 PMCID:PMC9036616
  • Modaresi SM, Wei W, Marques E, DaSilva NA, Slitt AL. 2022. Per- and polyfluoroalkyl substances (PFAS) augment adipogenesis and shift the proteome in murine 3T3-L1 adipocytes. Toxicology 465:doi:10.1016/j.tox.2021.153044 PMID:34800597 PMCID:PMC8756374
  • Naumann A, Alesio J, Poonia M, Bothun GD. 2022. PFAS fluidize synthetic and bacterial lipid monolayers based on hydrophobicity and lipid charge. J Environ Chem Eng 10:107351. doi:10.1016/j.jece.2022.107351 PMID:35463622 PMCID:PMC9029377
  • Pickard HM, Ruyle BJ, Thackray CP, Chovancova A, Dassuncao C, Becanova J, Vojta S, Lohmann R, Sunderland E. 2022. PFAS and precursor bioaccumulation in freshwater recreational fish: implications for fish advisories. Environ Sci Technol 56(22):15573-15583. doi:10.1021/acs.est.2c03734 PMID:36280234 PMCID:PMC9670858
  • Robuck AR, Hudak CA, Agvent L, Emery G, Ryan PG, Perold V, Powers KD, Pedersen J, Thompson MA, Suca JJ, Moore MJ, Harms CA, Bugoni L, Shield G, Glass T, Wiley DN, Lohmann R. 2022. Birds of a feather eat plastic together: High levels of plastic ingestion in Great Shearwater adults and juveniles across their annual migratory cycle. Front. Mar. Sci 8:doi:10.3389/fmars.2021.719721
  • Rodgers KM, Swartz CH, Occhialini J, Bassignani P, McCurdy M, Schaider L. 2022. How well do product labels indicate the presence of PFAS in consumer items used by children and adolescents?. Environ Sci Technol doi:10.1021/acs.est.1c05175 PMID:35506608 PMCID:PMC9118540
  • Sun JM, Kelly B, Gobas FA, Sunderland EM. 2022. A food web bioaccumulation model for the accumulation of per- and polyfluoroalkyl substances (PFAS) in fish: how important is renal elimination?. Environ Sci Process Impacts 13:doi:10.1039/d2em00047d PMID:35678632
  • Wilkinson BP, Robuck AR, Lohmann R, Pickard HM, Jodice PG. 2022. Urban proximity while breeding is not a predictor of perfluoroalkyl substance contamination in the eggs of brown pelicans. Sci Total Environ 803(11):doi:10.1016/j.scitotenv.2021.150110 PMID:34525704
  • Zhang C, McElroy AC, Liberatore H, Alexander NL, Knappe D. 2022. Stability of per- and polyfluoroalkyl substances in solvents relevant to environmental and toxicological analysis. Environ Sci Technol doi:10.1021/acs.est.1c03979 PMID:34734715 PMCID:PMC9065217

2021

  • Alesio J, Slitt AL, Bothun GD. 2021. Critical new insights into the binding of poly- and perfluoroalkyl substances (PFAS) to albumin protein. Chemosphere 287(Pt1):131979. doi:10.1016/j.chemosphere.2021.131979 PMID:34450368 (ahead of print)
  • Amaeze O, Eng H, Horlbogen L, Varma MV, Slitt AL. 2021. Cytochrome P450 enzyme inhibition and herb-drug interaction potential of medicinal plant extracts used for management of diabetes in Nigeria. Eur J Drug Metab Pharmacokinet 46(3):437-450. doi:10.1007/s13318-021-00685-1 PMID:33844145
  • Amaeze O, Marques E, Wei W, Lazzaro S, Johnson N, Varma MV, Slitt AL. 2021. Evaluation of Nigerian medicinal plants extract on human P-glycoprotein and Cytochrome P450 enzyme induction: Implications for herb-drug interaction. Curr Drug Metab 22(14):PMID:34915831
  • Basaly V, Hill J, Bihaqi SW, Marques E, Slitt AL, Zawia NH. 2021. Developmental perfluorooctanesulfonic acid (PFOS) exposure as a potential risk factor for late-onset Alzheimer's disease in CD-1 mice and SH-SY5Y cells. Neurotoxicology 86:26-36. doi:10.1016/j.neuro.2021.06.008 PMID:34224775 (ahead of print)
  • Becanova J, Saleeba Z, Stone A, Robuck AR, Hurt RH, Lohmann R. 2021. A graphene-based hydrogel monolith with tailored surface chemistry for PFAS passive sampling. Environ Sci Nano 14:doi:10.1039/D1EN00517K
  • Birukov A, Andersen LB, Andersen M, Nielsen JH, Nielsen F, Kyhl HB, Jorgensen JS, Grandjean P, Dechend R, Jensen TK. 2021. Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort. Environ Int 151:106442. doi:10.1016/j.envint.2021.106442 PMID:33610053
  • Blomberg AJ, Shih Y, Messerlian C, Jorgensen LH, Weihe P, Grandjean P. 2021. Early-life associations between per- and polyfluoroalkyl substances and serum lipids in a longitudinal birth cohort. Environ Res 200:111400. doi:10.1016/j.envres.2021.111400 PMID:34081971 PMCID:PMC8403652
  • Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Wang Z. 2021. Finding essentiality feasible: Common questions and misinterpretations concerning the 'essential-use' concept. Environ Sci Process Impacts 23(8):doi:10.1039/d1em00180a PMID:34190275 (ahead of print)
  • Dalsager L, Christensen N, Halekoh U, Timmermann CA, Nielsen F, Kyhl HB, Husby S, Grandjean P, Jensen TK, Andersen HR. 2021. Exposure to perfluoroalkyl substances during fetal life and hospitalization for infectious disease in childhood: A study among 1,503 children from the Odense Child Cohort. Environ Int 149:106395. doi:10.1016/j.envint.2021.106395 PMID:33508532
  • Dalsager L, Jensen TK, Nielsen F, Grandjean P, Bilenberg N, Andersen HR. 2021. No association between maternal and child PFAS concentrations and repeated measures of ADHD symptoms at age 21/2 and 5 years in children from the Odense Child Cohort. Neurotoxicol Teratol 88:PMID:34563660
  • De Silva AO, Armitage JM, Bruton TA, Dassuncao C, Heiger-Bernays WJ, Hu XC, Karrman A, Kelly B, Ng CA, Robuck AR, Sun M, Webster TF, Sunderland EM. 2021. PFAS exposure pathways for humans and wildlife: A synthesis of current knowledge and key gaps in understanding. Environ Toxicol Chem 40(3):631-657. doi:10.1002/etc.4935 PMID:33201517 PMCID:PMC7906948
  • Etzel RA, Grandjean P, Ozonoff DM. 2021. Environmental epidemiology in a crossfire. Environmental Health 20(1):91. doi:10.1186/s12940-021-00776-1 PMID:34412648 PMCID:PMC8375458
  • Fedorenko M, Alesio J, Fedorenko A, Slitt AL, Bothun GD. 2021. Dominant entropic binding of perfluoroalkyl substances (PFASs) to albumin protein revealed by 19 F NMR. Chemosphere 263(9):doi:10.1016/j.chemosphere.2020.128083 PMID:33297081
  • Gardener H, Sun Q, Grandjean P. 2021. PFAS concentration during pregnancy in relation to cardiometabolic health and birth outcomes. Environ Res 192:110287. doi:10.1016/j.envres.2020.110287 PMID:33038367 PMCID:PMC7736328
  • Hamilton MC, Heintz MM, Pfohl M, Marques E, Ford L, Slitt AL, Baldwin WS. 2021. Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic mice compared to Cyp2b-null mice is relieved by a high-fat diet (HFD). Food Chem Toxicol 152:112175. doi:10.1016/j.fct.2021.112175 PMID:33838175 PMCID:PMC8154739
  • Hill NI, Becanova J, Lohmann R. 2021. A sensitive method for the detection of legacy and emerging per- and polyfluorinated alkyl substances (PFAS) in dairy milk. Anal Bioanal Chem 414(3):doi:10.1007/s00216-021-03575-2 PMID:34355253 (ahead of print)
  • Marques E, Agudelo J, Kaye EM, Modaresi SM, Pfohl M, Becanova J, Wei W, Polunas M, Goedken M, Slitt AL. 2021. The role of maternal high fat diet on mouse pup metabolic endpoints following perinatal PFAS and PFAS mixture exposure. Toxicology 462(15):152921. doi:10.1016/j.tox.2021.152921 PMID:34464680 PMCID:PMC8554779
  • Marques E, Formato E, Liang W, Leonard E, Timme-Laragy AR. 2021. Relationships between type 2 diabetes, cell dysfunction, and redox signaling: A meta-analysis of single-cell gene expression of human pancreatic a- and B-cells. J Diabetes doi:10.1111/1753-0407.13236 PMID:34725923 PMCID:PMC8746116
  • Morales-McDevitt ME, Becanova J, Blum A, Bruton TA, Vojta S, Woodward M, Lohmann R. 2021. The air that we breathe: Neutral and volatile PFAS in indoor air. Environ Sci Technol Lett 8:897-902. doi:10.1021/acs.estlett.1c00481
  • Morales-McDevitt ME, Dunn M, Habib A, Vojta S, Becanova J, Lohmann R. 2021. Poly- and perfluorinated alkyl substances in air and water from Dhaka, Bangladesh. Environ Toxicol Chem doi:10.1002/etc.5255 PMID:34793599
  • Ng CA, Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Patton S, Scheringer M, Trier X, Wang Z. 2021. Addressing urgent questions for PFAS in the 21st century. Environ Sci Technol 55(19):12755-12765. doi:10.1021/acs.est.1c03386 PMID:34519210 PMCID:PMC8590733
  • Pfohl M, DaSilva NA, Marques E, Agudelo J, Liu C, Goedken M, Slitt AL, Seeram NP, Ma H. 2021. Hepatoprotective and anti-inflammatory effects of a standardized pomegranate (Punica granatum) fruit extract in high fat diet-induced obese C57BL/6 mice. Int J Food Sci Nutr 72(4):499-510. doi:10.1080/09637486.2020.1849041 PMID:33203257
  • Pfohl M, Marques E, Auclair A, Barlock BJ, Jamwal R, Goedken M, Akhlaghi F, Slitt AL. 2021. An 'omics approach to unraveling the paradoxical effect of diet on perfluorooctanesulfonic acid (PFOS) and perfluorononanoic acid (PFNA)-induced hepatic steatosis. Toxicol Sci 180:277-294. doi:10.1093/toxsci/kfaa172 PMID:33483757 PMCID:PMC8041463
  • Robuck AR, McCord JP, Strynar M, Cantwell MG, Wiley DN, Lohmann R. 2021. Tissue-specific distribution of legacy and novel per- and polyfluoroalkyl substances in juvenile seabirds. Environ Sci Technol Lett 8:
  • Ruyle BJ, Pickard HM, LeBlanc DR, Tokranov AK, Thackray CP, Hu XC, Vecitis CD, Sunderland EM. 2021. Isolating the AFFF signature in coastal watersheds using oxidizable PFAS precursors and unexplained organofluorine. Environ Sci Technol 55(6):3686-3695. doi:10.1021/acs.est.0c07296 PMID:33667081
  • Ruyle BJ, Thackray CP, McCord JP, Strynar M, Mauge-Lewis KA, Fenton SE, Sunderland EM. 2021. Reconstructing the composition of per- and polyfluoroalkyl substances in contemporary aqueous film-forming foams. Environ Sci Technol Lett 8:59-65. doi:10.1021/acs.estlett.0c00798 PMID:33628855 PMCID:PMC7898139
  • Salter DM, Wei W, Nahar PP, Marques E, Slitt AL. 2021. Perfluorooctanesulfonic acid (PFOS) thwarts the beneficial effects of calorie restriction and Metformin. Toxicol Sci 182(1):doi:10.1093/toxsci/kfab043 PMID:33844015 (ahead of print)
  • Shih Y, Blomberg AJ, Bind M, Holm D, Nielsen F, Heilmann C, Weihe P, Grandjean P. 2021. Serum vaccine antibody concentrations in adults exposed to per- and polyfluoroalkyl substances: A birth cohort in the Faroe Islands. J Immunotoxicol 18(1):85-92. PMID:34143710 (ahead of print)
  • Shih Y, Blomberg AJ, Jorgensen LH, Weihe P, Grandjean P. 2021. Early-life exposure to perfluoroalkyl substances in relation to serum adipokines in a longitudinal birth cohort. Environ Res 204(7):111905. doi:10.1016/j.envres.2021.111905 PMID:34419464
  • Tokranov AK, LeBlanc DR, Pickard HM, Ruyle BJ, Barber LB, Hull RB, Sunderland EM, Vecitis CD. 2021. Surface-water/groundwater boundaries affect seasonal PFAS concentrations and PFAA precursor transformations. Environ Sci Process Impacts 13:PMID:34779453
  • Valvi D, Hojlund K, Coull BA, Nielsen F, Weihe P, Grandjean P. 2021. Life-course exposure to perfluoroalkyl substances in relation to markers of glucose homeostasis in early adulthood. J Clin Endocrinol Metab 106(8):2495-2504. doi:10.1210/clinem/dgab267 PMID:33890111 PMCID:PMC8277200
  • Wu Q, Coumoul X, Grandjean P, Barouki R, Audouze K. 2021. Endocrine disrupting chemicals and COVID-19 relationships: A computational systems biology approach. Environ Int 157:doi:10.1016/j.envint.2020.106232 PMID:33223326 PMCID:PMC7831776
  • Young AS, Sparer-Fine EH, Pickard HM, Sunderland EM, Peaslee GF, Allen JG. 2021. Per- and polyfluoroalkyl substances (PFAS) and total fluorine in fire station dust. J Expo Sci Environ Epidemiol 31(5):doi:10.1038/s41370-021-00288-7 PMID:33542478 (ahead of print)

2020

  • Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Scheringer M, Vierke L, Wang Z. 2020. Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to protect human and environmental health. Environ Sci Process Impacts 22:1444-1460. doi:10.1039/D0EM00147C PMID:32495786
  • Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lohmann R, Ng CA, Scheringer M, Wang Z. 2020. The high persistence of PFAS is sufficient for their management as a chemical class. Environ Sci Process Impacts doi:10.1039/d0em00355g PMID:33230514
  • Gluge J, Scheringer M, Cousins IT, Goldenman G, Herzke D, Lohmann R, DeWitt JC, Ng CA, Trier X, Wang Z. 2020. An overview of the uses of per- and polyfluoroalkyl substances (PFAS). Environ Sci Process Impacts 22:2345-2373. doi:10.1039/d0em00291g PMID:33125022 PMCID:PMC7784712
  • Grandjean P, Timmermann CA, Kruse M, Nielsen F, Vinholt PJ, Boding L, Heilmann C, Molbak K. 2020. Severity of COVID-19 at elevated exposure to perfluorinated alkylates. PLoS One 15:doi:10.1371/journal.pone.0244815 PMID:33382826
  • Jensen RC, Andersen M, Larsen PV, Glintborg D, Dalgard C, Timmermann CA, Nielsen F, Sandberg MB, Andersen HR, Christesen HT, Grandjean P, Jensen TK. 2020. Prenatal exposures to perfluoroalkyl acids and associations with markers of adiposity and plasma lipids in infancy: An Odense Child Cohort study. Environ Health Perspect 128(7):77001. doi:10.1289/EHP5184 PMID:32628516 PMCID:PMC7338787
  • Joerss H, Xie Z, Wagner CC, von Appen W, Sunderland EM, Ebinghaus R. 2020. Transport of legacy perfluoroalkyl substances and the replacement compound HFPO-DA through the Atlantic gateway to the Arctic Ocean - is the Arctic a sink or a source?. Environ Sci Technol 54(16):9958-9967. doi:10.1021/acs.est.0c00228 PMID:32806910
  • Kwiatkowski C, Andrews DQ, Birnbaum LS, Bruton TA, DeWitt JC, Knappe D, Maffini MV, Miller M, Pelch KE, Reade A, Soehl A, Trier X, Venier M, Wagner CC, Wang Z, Blum A. 2020. Scientific basis for managing PFAS as a chemical class. Environ Sci Technol Lett 7:532-543. doi:10.1021/acs.estlett.0c00255
  • Landrigan PJ, Stegeman JJ, Fleming LE, Allemand D, Anderson DM, Backer L, Brucker-Davis F, Chevalier N, Corra L, Czerucka D, Bottein MD, Demeneix B, Depledge MH, Deheyn DD, Dorman CJ, Fenichel P, Fisher S, Gaill F, Galgani F, Gaze WH, Giuliano L, Grandjean P, Hahn ME, Hamdoun A, Hess P, Judson B, Laborde A, McGlade J, Mu J, Mustapha A, Neira M, Noble RT, Pedrotti ML, Reddy C, Rocklov J, Scharler UM, Shanmugam H, Taghian G, van de Water JA, Vezzulli L, Weihe P, Zeka A, Raps H, Rampal P. 2020. Human health and ocean pollution. Ann Glob Health 86:64. doi:10.5334/aogh.2831 PMID:33354517 PMCID:PMC7731724
  • Liu G, Zhang B, Hu Y, Rood J, Liang L, Qi L, Bray GA, DeJonge L, Coull BA, Grandjean P, Furtado JD, Sun Q. 2020. Associations of perfluoroalkyl substances with blood lipids and apolipoproteins in lipoprotein subspecies: The POUNDS-lost study. Environmental Health 19:doi:10.1186/s12940-020-0561-8 PMID:31931806 PMCID:PMC6958662
  • Lohmann R, Cousins IT, DeWitt JC, Gluge J, Goldenman G, Herzke D, Lindstrom AB, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Wang Z. 2020. Are fluoropolymers really of low concern for human and environmental health and separate from other PFAS?. Environ Sci Technol 54(20):12820-12828. doi:10.1021/acs.est.0c03244 PMID:33043667 PMCID:PMC7700770
  • Marques E, Pfohl M, Auclair A, Jamwal R, Barlock BJ, Sammoura FM, Goedken M, Akhlaghi F, Slitt AL. 2020. Perfluorooctanesulfonic acid (PFOS) administration shifts the hepatic proteome and augments dietary outcomes related to hepatic steatosis in mice. Toxicol Appl Pharmacol 408:doi:10.1016/j.taap.2020.115250 PMID:32979393
  • Paragot N, Becanova J, Karaskova P, Prokes R, Klanova J, Lammel G, Degrendele C. 2020. Multi-year atmospheric concentrations of per- and polyfluoroalkyl substances (PFASs) at a background site in central Europe. Environ Pollut 265:8. doi:10.1016/j.envpol.2020.114851 PMID:32474357
  • Pfohl M, Ingram L, Marques E, Auclair A, Barlock BJ, Jamwal R, Anderson D, Cummings BS, Slitt AL. 2020. Perfluorooctanesulfonic acid and perfluorohexanesulfonic acid alter the blood lipidome and the hepatic proteome in a murine model of diet-induced obesity. Toxicol Sci 178:311-324. doi:10.1093/toxsci/kfaa148 PMID:32991729 PMCID:PMC7751193
  • Robuck AR, Cantwell MG, McCord JP, Addison LM, Pfohl M, Strynar M, McKinney R, Katz D, Wiley DN, Lohmann R. 2020. Legacy and novel per- and polyfluoroalkyl substances in juvenile seabirds from the U.S. Atlantic Coast. Environ Sci Technol 54(20):12938-12948. doi:10.1021/acs.est.0c01951 PMID:32894676
  • Timmermann CA, Jensen KJ, Nielsen F, Budtz-Jorgensen E, van der Klis F, Benn CS, Grandjean P, Fisker AB. 2020. Serum Perfluoroalkyl Substances, Vaccine Responses, and Morbidity in a Cohort of Guinea-Bissau Children. Environ Health Perspect 128:doi:10.1289/ehp6517 PMID:32772733 PMCID:PMC7416537
  • Waterfield G, Rogers M, Grandjean P, Auffhammer M, Sunding D. 2020. Reducing exposure to high levels of perfluorinated compounds in drinking water improves reproductive outcomes: Evidence from an intervention in Minnesota. Environ Health 19(1):42. doi:10.1186/s12940-020-00591-0 PMID:32321520 PMCID:PMC7178962

2019

  • Ammitzboll C, Bornsen L, Petersen ER, Oturai AB, Sondergaard HB, Grandjean P, Sellebjerg F. 2019. Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation. J Neuroimmunol 330:90-95. doi:10.1016/j.jneuroim.2019.03.002 PMID:30852181 PMCID:PMC6461219
  • Cordner A, De La Rosa VY, Schaider LA, Rudel RA, Richter L, Brown P. 2019. Guideline levels for PFOA and PFOS in drinking water: the role of scientific uncertainty, risk assessment decisions, and social factors. J Expo Sci Environ Epidemiol 29:157-171. doi:10.1038/s41370-018-0099-9 PMID:30622333 PMCID:PMC6455940
  • Cousins IT, Goldenman G, Herzke D, Lohmann R, Miller M, Ng CA, Patton S, Scheringer M, Trier X, Vierke L, Wang Z, DeWitt JC. 2019. The concept of essential use for determining when uses of PFASs can be phased out. Environ Sci Process Impacts 21:1803-1815. doi:10.1039/c9em00163h PMID:31204421 PMCID:PMC6992415
  • Dassuncao C, Pickard HM, Pfohl M, Tokranov AK, Li M, Mikkelsen B, Slitt AL, Sunderland EM. 2019. Phospholipid levels predict the tissue distribution of poly- and perfluoroalkyl substances in a marine mammal. Environ Sci Technol Lett 6(3):119-125. doi:10.1021/acs.estlett.9b00031
  • DeWitt JC, Blossom SJ, Schaider L. 2019. Exposure to per-fluoroalkyl and polyfluoroalkyl substances leads to immunotoxicity: epidemiological and toxicological evidence. J Expo Sci Environ Epidemiol 29:148-156. doi:10.1038/s41370-018-0097-y PMID:30482935 PMCID:PMC6380927
  • Eryasa B, Grandjean P, Nielsen F, Valvi D, Zmirou-Navier D, Sunderland EM, Weihe P, Oulhote Y. 2019. Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances. Environ Int 130:doi:10.1016/j.envint.2019.05.068 PMID:31200157 PMCID:PMC7029428
  • Grandjean P. 2019. Developmental fluoride neurotoxicity: An updated review. Environmental Health 18:doi:10.1186/s12940-019-0551-x PMID:31856837 PMCID:PMC6923889
  • Grandjean P, Abdennebi-Najar L, Barouki R, Cranor CF, Etzel RA, Gee D, Heindel J, Hougaard KS, Hunt P, Nawrot T, Prins GS, Ritz B, Soffritti M, Sunyer J, Weihe P. 2019. Timescales of developmental toxicity impacting on research and needs for intervention. Basic Clin Pharmacol Toxicol 125:70-80. doi:10.1111/bcpt.13162 PMID:30387920 PMCID:PMC6497561
  • Hu XC, Tokranov AK, Liddie J, Zhang X, Grandjean P, Hart JE, Laden F, Sun Q, Yeung LW, Sunderland EM. 2019. Tap water contributions to plasma concentrations of poly- and perfluoroalkyl substances (PFAS) in a nationwide prospective cohort of U.S. women. Environ Health Perspect doi:10.1289/EHP4093 PMID:31170009 PMCID:PMC6792361
  • Khairy M, Noonan GO, Lohmann R. 2019. Uptake of hydrophobic organic compounds, including organochlorine pesticides, polybrominated diphenyl ethers, and perfluoroalkyl acids in fish and blue crabs of the lower Passaic River, New Jersey, USA. Environ Toxicol Chem 38(4):872-882. doi:10.1002/etc.4354 PMID:30614049 PMCID:PMC6475076
  • Lim X. 2019. Tainted water: the scientists tracing thousands of fluorinated chemicals in our environment. Nature 566:26-29. doi:10.1038/d41586-019-00441-1 PMID:30728524
  • Shaffer RM, Sellers SP, Baker MG, de Buen Kalman R, Frostad J, Suter MK, Anenberg SC, Balbus J, Basu N, Bellinger DC, Birnbaum LS, Brauer M, Cohen A, Ebi KL, Fuller R, Grandjean P, Hess JJ, Kogevinas M, Kumar P, Landrigan PJ, Lanphear BP, London SJ, Rooney AA, Stanaway JD, Trasande L, Walker K, Hu H. 2019. Improving and expanding estimates of the global burden of disease due to environmental health risk factors. Environ Health Perspect 127:doi:10.1289/EHP5496 PMID:31626566 PMCID:PMC6867191
  • Shelly C, Grandjean P, Oulhote Y, Plomgaard P, Frikke-Schmidt R, Nielsen F, Zmirou-Navier D, Weihe P, Valvi D. 2019. Early life exposures to perfluoroalkyl substances in relation to adipokine hormone levels at birth and during childhood. J Clin Endocrinol Metab 104(11):5338-48. doi:10.1210/jc.2019-00385 PMID:31216000 PMCID:PMC6773461 (ahead of print)
  • Sunderland EM, Hu XC, Dassuncao C, Tokranov AK, Wagner CC, Allen JG. 2019. A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects. J Expo Sci Environ Epidemiol 29:131-147. doi:10.1038/s41370-018-0094-1 PMID:30470793 PMCID:PMC6380916
  • Susmann HP, Schaider L, Rodgers KM, Rudel RA. 2019. Dietary habits related to food packaging and population exposure to PFASs. Environ Health Perspect 127:doi:10.1289/EHP4092 PMID:31596611 PMCID:PMC6867167
  • Tokranov AK, Nishizawa N, Amadei CA, Zenobio JE, Pickard HM, Allen JG, Vecitis CD, Sunderland EM. 2019. How do we measure poly- and perfluoroalkyl substances (PFASs) at the surface of consumer products?. Environ Sci Technol Lett 6(1):38-43. doi:10.1021/acs.estlett.8b00600
  • Ugai T, Ito H, Oze I, Saito E, Rahman S, Boffetta P, Gupta PC, Sawada N, Tamakoshi A, Shu X, Koh W, Gao Y, Sadakane A, Tsuji I, Park SK, Nagata C, You S, Pednekar MS, Tsugane S, Cai H, Yuan J, Xiang Y, Ozasa K, Tomata Y, Kanemura S, Sugawara Y, Wada K, Chen C, Yoo K, Chia K, Ahsan H, Zheng W, Inoue M, Kang D, Potter JD, Matsuo K. 2019. Association of BMI, Smoking, and Alcohol with Multiple Myeloma Mortality in Asians: A Pooled Analysis of More than 800,000 Participants in the Asia Cohort Consortium. Cancer Epidemiol Biomarkers Prev 28:1861-1867. doi:10.1158/1055-9965.Epi-19-0389 PMID:31399476
  • Xiao C, Grandjean P, Valvi D, Nielson F, Jensen TK, Weihe P, Oulhote Y. 2019. Associations of Exposure to Perfluoroalkyl Substances With Thyroid Hormone Concentrations and Birth Size. J Clin Endocrinol Metab 105:doi:10.1210/clinem/dgz147
  • Zhang X, Lohmann R, Sunderland EM. 2019. Poly- and perfluoroalkyl substances in seawater and plankton from the Northwestern Atlantic Margin. Environ Sci Technol 53:12348-12356. doi:10.1021/acs.est.9b03230 PMID:31565932 PMCID:PMC6992416

2018

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