Project Title: | MECHANISMS OF MANGANESE NEUROTOXICITY |
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PI: | Bowman, Aaron B |
Institution: | Purdue University |
Grant Number: | R01ES010563 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Anandamide and WIN 55212-2 Afford Protection in Rat Brain Mitochondria in a Toxic Model Induced by 3 ... | Maya-López, Marisol; Monsalvo-Maraver, Luis Angel; Delgado-Arzate, Ana Laura; Olivera-Pérez, Car ... | R01ES007331, R01ES010563 | Mol Neurobiol (2024 Sep) | 38307967 | 2024 |
Application of Single Cell Gene Expression Technologies to Neurotoxicology. | Tukker, Anke M; Bowman, Aaron B | R01ES007331, R01ES010563 | Curr Opin Toxicol (2024 Mar) | 38617035 | 2024 |
Assessment of trace element and mineral levels in students from Turkmenistan in comparison to Iran a ... | Kirichuk, Anatoly A; Skalny, Anatoly V; Schaumlöffel, Dirk; Kovaleva, Irina A; Korobeinikova, T ... | R01ES010563 | J Trace Elem Med Biol (2024 Jul) | 38579500 | 2024 |
Clinical case analysis of 32 children aged 0-6 years with lead poisoning in Nanning, China. | Wei, Yi-Fei; Gan, Cui-Liu; Xu, Fang; Fang, Yuan-Yuan; Zhang, Bao-Dan; Li, Wu-Shu; Nong, Kang; ... | R01ES010563 | Toxicol Ind Health (2024) | 37984499 | 2024 |
Heavy Metal Interactions with Neuroglia and Gut Microbiota: Implications for Huntington's Disease. | Tizabi, Yousef; Bennani, Samia; El Kouhen, Nacer; Getachew, Bruk; Aschner, Michael | R01ES010563 | Cells (2024 Jul 03) | 38994995 | 2024 |
Interactions Between the Ubiquitin-Proteasome System, Nrf2, and the Cannabinoidome as Protective Str ... | Monsalvo-Maraver, Luis Angel; Ovalle-Noguez, Enid A; Nava-Osorio, Jade; Maya-López, Marisol; Ran ... | R01ES010563 | Neurotox Res (2024 Feb 23) | 38393521 | 2024 |
Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets. | Carvalho, Fernanda Vidal; Landis, Harold E; Getachew, Bruk; Silva, Victor Diogenes Amaral; Ribei ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2024) | 38770370 | 2024 |
Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17β-estradiol affor ... | Nyarko-Danquah, Ivan; Pajarillo, Edward; Kim, Sanghoon; Digman, Alexis; Multani, Harpreet Kaur; ... | R01ES010563, R01ES031282 | Neurotoxicology (2024 Jul) | 38857675 | 2024 |
Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous ne ... | Skalny, Anatoly V; Aschner, Michael; Gritsenko, Viktor A; Martins, Airton C; Tizabi, Yousef; Ko ... | R01ES010563 | Adv Neurotoxicol (2024) | 38741946 | 2024 |
S-allyl-cysteine triggers cytotoxic events in rat glioblastoma RG2 and C6 cells and improves the eff ... | Reyes-Soto, Carolina Y; Ramírez-Carreto, Ricardo J; Ortíz-Alegría, Luz Belinda; Silva-Palacios, ... | R01ES010563 | Discov Oncol (2024 Jul 08) | 38977545 | 2024 |
Should ebselen be considered for the treatment of mercury intoxication? A minireview. | Barbosa, Nilda V; Aschner, Michael; Tinkov, Alexey A; Farina, Marcelo; Rocha, João Batista Teix ... | R01ES007331, R01ES010563 | Toxicol Mech Methods (2024 Jan) | 37731353 | 2024 |
Utility of zebrafish-based models in understanding molecular mechanisms of neurotoxicity mediated by ... | Adedara, Isaac A; Mohammed, Khadija A; Canzian, Julia; Ajayi, Babajide O; Farombi, Ebenezer O; ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2024 May) | 38741945 | 2024 |
A Reliable Method Based on Liquid Chromatography-Tandem Mass Spectrometry for the Simultaneous Quant ... | Weishaupt, Ann-Kathrin; Kubens, Laura; Ruecker, Lysann; Schwerdtle, Tanja; Aschner, Michael; Bo ... | R01ES007331, R01ES010563 | Molecules (2023 Jul 13) | 37513246 | 2023 |
Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics and its Implications for Alzheim ... | Monsalvo-Maraver, Luis Ángel; Maya-López, Marisol; Rangel-López, Edgar; Túnez, Isaac; Tinkov, A ... | R01ES007331, R01ES010563 | CNS Neurol Disord Drug Targets (2023) | 35713133 | 2023 |
Association between Heavy Metals, Metalloids and Metabolic Syndrome: New Insights and Approaches. | Martins, Airton C; Ferrer, Beatriz; Tinkov, Alexey A; Caito, Samuel; Deza-Ponzio, Romina; Skaln ... | R01ES007331, R01ES010563 | Toxics (2023 Aug 03) | 37624175 | 2023 |
Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxi ... | Pajarillo, Edward; Nyarko-Danquah, Ivan; Digman, Alexis; Vied, Cynthia; Son, Deok-Soo; Lee, Ja ... | R01ES007331, R01ES010563, R01ES031282 | Glia (2023 Feb) | 36300569 | 2023 |
Biological effects of the frequent application of a copper-containing fungicide on the fruit fly Dro ... | Zamberlan, Daniele; Rieder, Guilherme; Silva, Luis; Teixeira da Rocha, Joao Batista | R01ES007331, R01ES010563 | Res Sq (2023 Feb 09) | 36798215 | 2023 |
Butyrate Protects and Synergizes with Nicotine against Iron- and Manganese-induced Toxicities in Cel ... | Tizabi, Yousef; Getachew, Bruk; Aschner, Michael | R01ES010563 | Neurotox Res (2023 Dec 14) | 38095760 | 2023 |
Butyrate protects and synergizes with nicotine against iron- and manganese-induced toxicities in cel ... | Tizabi, Yousef; Getachew, Bruk; Aschner, Michael | R01ES007331, R01ES010563 | Res Sq (2023 Oct 05) | 37886507 | 2023 |
Cobalt nanoparticles induce mitochondrial damage and β-amyloid toxicity via the generation of reacti ... | Chen, Jingrong; Chen, Cheng; Wang, Na; Wang, Chunyu; Gong, Zhaohui; Du, Jingxian; Lai, Hongli ... | R01ES007331, R01ES010563 | Neurotoxicology (2023 Mar) | 36716931 | 2023 |
COVID-19 vaccination and case fatality rates: a case report in a Brazilian municipality. | Paludetto Junior, Moacir; Olak, André S; Passarelli-Araujo, Hisrael; Susuki, Aline M; Aschner, ... | R01ES010563 | Cad Saude Publica (2023) | 37018770 | 2023 |
Dopaminergic modulation by quercetin: In silico and in vivo evidence using Caenorhabditis elegans as ... | Salgueiro, Willian Goulart; Soares, Marcell Valandro; Martins, Cassiano Fiad; Paula, Fávero Reis ... | R01ES007331, R01ES010563 | Chem Biol Interact (2023 Sep 01) | 37348670 | 2023 |
Evaluation of neurotoxicity and the role of oxidative stress of cobalt nanoparticles, titanium dioxi ... | Chen, Cheng; Chen, Jingrong; Lin, Xinpei; Yang, Jiafu; Qu, Huimin; Li, Lisong; Zhang, Duanyan ... | R01ES007331, R01ES010563 | Toxicol Sci (2023 Oct 30) | 37584706 | 2023 |
Genetic factors in methylmercury-induced neurotoxicity: What have we learned from Caenorhabditis ele ... | Ke, Tao; Junior, Fernando Barbosa; Santamaria, Abel; Bowman, Aaron B; Aschner, Michael | R01ES007331, R01ES010563 | Adv Neurotoxicol (2023) | 37389202 | 2023 |
Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neuro ... | Ückert, Anna-Katharina; Rütschlin, Sina; Gutbier, Simon; Wörz, Nathalie Christine; Miah, Mahfuz ... | R01ES007331, R01ES010563 | Environ Int (2023 Oct) | 37797477 | 2023 |
IGF/mTORC1/S6 Signaling Is Potentiated and Prolonged by Acute Loading of Subtoxicological Manganese ... | Tang, Xueqi; Balachandran, Rekha C; Aschner, Michael; Bowman, Aaron B | R01ES010563 | Biomolecules (2023 Aug 08) | 37627294 | 2023 |
Interaction of Heavy Metal Lead with Gut Microbiota: Implications for Autism Spectrum Disorder. | Tizabi, Yousef; Bennani, Samia; El Kouhen, Nacer; Getachew, Bruk; Aschner, Michael | R01ES007331, R01ES010563 | Biomolecules (2023 Oct 19) | 37892231 | 2023 |
MiR-130/SNAP-25 axis regulate presynaptic alteration in anterior cingulate cortex involved in lead i ... | Wang, Tao; Guan, Rui-Li; Zou, Yun-Feng; Zheng, Gang; Shen, Xue-Feng; Cao, Zi-Peng; Yang, Rui- ... | R01ES007331, R01ES010563 | J Hazard Mater (2023 Feb 05) | 36332276 | 2023 |
Mitochondria in the Spotlight: C. elegans as a Model Organism to Evaluate Xenobiotic-Induced Dysfunc ... | Martins, Airton C; Virgolini, Miriam B; Ávila, Daiana Silva; Scharf, Pablo; Li, Jung; Tinkov, ... | R01ES007331, R01ES010563 | Cells (2023 Aug 22) | 37681856 | 2023 |
Morphological alterations in C57BL/6 mouse intestinal organoids as a tool for predicting chemical-in ... | Wang, Ziwei; Chen, Shen; Pang, Yaqin; Ye, Lizhu; Zhang, Qi; Jiang, Xinhang; Zhang, Rui; Li, ... | R01ES007331, R01ES010563 | Arch Toxicol (2023 Apr) | 36806895 | 2023 |
Nauphoeta cinerea as an emerging model in neurotoxicology. | Adedara, Isaac A; Mohammed, Khadija A; Canzian, Julia; Rosemberg, Denis B; Aschner, Michael; Fa ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2023) | 37389201 | 2023 |
Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans. | Agarrayua, Danielle Araujo; Silva, Aline Castro; Saraiva, Nariani Rocha; Soares, Ana Thalita; As ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2023) | 37384197 | 2023 |
Perspective on halogenated organic compounds. | Kodavanti, Prasada Rao S; Costa, Lucio G; Aschner, Michael | R01ES007331, R01ES010563 | Adv Neurotoxicol (2023) | 37920427 | 2023 |
Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants. | Kim, Sanghoon; Pajarillo, Edward; Nyarko-Danquah, Ivan; Aschner, Michael; Lee, Eunsook | R01ES010563, R01ES031282 | Cells (2023 Feb 15) | 36831289 | 2023 |
Signaling Pathways Involved in Manganese-Induced Neurotoxicity. | Cheng, Hong; Villahoz, Beatriz Ferrer; Ponzio, Romina Deza; Aschner, Michael; Chen, Pan | R01ES010563 | Cells (2023 Dec 14) | 38132161 | 2023 |
The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflam ... | Pajarillo, Edward; Kim, Sanghoon; Digman, Alexis; Dutton, Matthew; Son, Deok-Soo; Aschner, Mic ... | R01ES010563, R01ES031282 | J Biol Chem (2023 Jul) | 37269951 | 2023 |
Therapeutic m6A Eraser ALKBH5 mRNA-Loaded Exosome-Liposome Hybrid Nanoparticles Inhibit Progression ... | Wu, Shenshen; Yun, Jun; Tang, Weiyan; Familiari, Giuseppe; Relucenti, Michela; Wu, Jiong; Li, ... | R01ES007331, R01ES010563 | ACS Nano (2023 Jun 27) | 37310898 | 2023 |
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a co ... | Chen, Shen; Li, Miao; Zhang, Rui; Ye, Lizhu; Jiang, Yue; Jiang, Xinhang; Peng, Hui; Wang, Zi ... | R01ES007331, R01ES010563 | Part Fibre Toxicol (2023 Apr 17) | 37069663 | 2023 |
An Update on the Critical Role of α-Synuclein in Parkinson's Disease and Other Synucleinopathies: fr ... | Serratos, Iris N; Hernández-Pérez, Elizabeth; Campos, Carolina; Aschner, Michael; Santamaría, A ... | R01ES010563 | Mol Neurobiol (2022 Jan) | 34750787 | 2022 |
Chemotherapeutic Risk lncRNA-PVT1 SNP Sensitizes Metastatic Colorectal Cancer to FOLFOX Regimen. | Wu, Shenshen; Yang, Xi; Tang, Weiyan; Familiari, Giuseppe; Relucenti, Michela; Aschner, Michae ... | R01ES007331, R01ES010563 | Front Oncol (2022) | 35433465 | 2022 |
CpG site-specific methylation as epi-biomarkers for the prediction of health risk in PAHs-exposed po ... | Ye, Lizhu; He, Zhini; Li, Daochuan; Chen, Liping; Chen, Shen; Guo, Ping; Yu, Dianke; Ma, Lu; ... | R01ES007331, R01ES010563 | J Hazard Mater (2022 Jun 05) | 35231813 | 2022 |
Determination of tipping point in course of PM2.5 organic extracts-induced malignant transformation ... | Chen, Shen; Li, Daochuan; Yu, Dianke; Li, Miao; Ye, Lizhu; Jiang, Yue; Tang, Shijie; Zhang, ... | R01ES007331, R01ES010563 | J Hazard Mater (2022 Mar 15) | 34933256 | 2022 |
Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, b ... | Yang, Bobo; Yin, Changsheng; Zhang, Yu; Xing, Guangwei; Wang, Suhua; Li, Fang; Aschner, Micha ... | R01ES010563 | Toxicol Res (Camb) (2022 Apr) | 35510234 | 2022 |
Effects of co-exposure to lead and manganese on learning and memory deficits. | Guan, Ruili; Wang, Tao; Dong, Xiaoru; Du, Kejun; Li, Juan; Zhao, Fang; Xu, Jie; Li, Bin; Zhe ... | R01ES010563 | J Environ Sci (China) (2022 Nov) | 35654517 | 2022 |
Epstein-Barr Virus-Encoded MicroRNA-BART18-3p Promotes Colorectal Cancer Progression by Targeting De ... | Meng, Qingtao; Sun, Hao; Wu, Shenshen; Familiari, Giuseppe; Relucenti, Michela; Aschner, Micha ... | R01ES007331, R01ES010563 | Adv Sci (Weinh) (2022 Dec) | 36307872 | 2022 |
Erratum for Chen et al. Perturbation of specific signaling pathways is involved in initiation of mou ... | R01ES007331, R01ES010563 | Hepatology (2022 May) | 35318702 | 2022 | |
Exposing the role of metals in neurological disorders: a focus on manganese. | Kim, Hyunjin; Harrison, Fiona E; Aschner, Michael; Bowman, Aaron B | R01ES007331, R01ES010563, R01ES031401 | Trends Mol Med (2022 Jul) | 35610122 | 2022 |
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically ... | Cukier, Holly N; Kim, Hyunjin; Griswold, Anthony J; Codreanu, Simona G; Prince, Lisa M; Sherrod ... | R01ES010563 | NPJ Parkinsons Dis (2022 Jun 29) | 35768426 | 2022 |
Hydrogen Sulfide (H2S) Signaling as a Protective Mechanism against Endogenous and Exogenous Neurotox ... | Aschner, Michael; Skalny, Anatoly V; Ke, Tao; da Rocha, Joao Bt; Paoliello, Monica Mb; Santamar ... | R01ES010563 | Curr Neuropharmacol (2022) | 35236265 | 2022 |
Iron overload and neurodegenerative diseases: What can we learn from Caenorhabditis elegans? | Martins, Airton C; Virgolini, Miriam B; Tinkov, Alexey A; Skalny, Anatoly V; Tirumala, Rohan P; ... | R01ES007331, R01ES010563 | Toxicol Res Appl (2022) | 35990536 | 2022 |
Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes. | Rizor, Asha; Pajarillo, Edward; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563, R01ES031282 | Toxicol Lett (2022 Feb 01) | 34800614 | 2022 |
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype. | Wilcox, Jordyn M; Consoli, David C; Paffenroth, Krista C; Spitznagel, Brittany D; Calipari, Eri ... | R01ES010563, R01ES031401 | Pharmacol Biochem Behav (2022 Feb) | 35063467 | 2022 |
Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies. | Pajarillo, Edward; Nyarko-Danquah, Ivan; Digman, Alexis; Multani, Harpreet Kaur; Kim, Sanghoon; ... | R01ES010563 | Front Pharmacol (2022) | 36605395 | 2022 |
Meteorological parameters and cases of COVID-19 in Brazilian cities: an observational study. | Olak, André S; Santos, Willian S; Susuki, Aline M; Pott-Junior, Henrique; V Skalny, Anatoly; Ti ... | R01ES007331, R01ES010563 | J Toxicol Environ Health A (2022 01 02) | 34474657 | 2022 |
Methylcyclopentadienyl Manganese Tricarbonyl Alter Behavior and Cause Ultrastructural Changes in the ... | Zhu, Qi-Feng; Lu, Li-Li; Fang, Yuan-Yuan; Wu, Jie; Huang, Zhao-Ying; Zheng, Xiao-Wei; Song, H ... | R01ES010563 | Neurochem Res (2022 Aug) | 35513760 | 2022 |
Neurotoxicity Evaluation of Nanomaterials Using C. elegans: Survival, Locomotion Behaviors, and Oxid ... | Zheng, Fuli; Chen, Cheng; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc (2022 Jul) | 35849041 | 2022 |
PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient ... | Chen, Shen; Chen, Liping; Ye, Lizhu; Jiang, Yue; Li, Qiong; Zhang, Haiyan; Zhang, Rui; Li, H ... | R01ES007331, R01ES010563 | J Hazard Mater (2022 02 15) | 34740159 | 2022 |
Prediction of COPD acute exacerbation in response to air pollution using exosomal circRNA profile an ... | Meng, Qingtao; Wang, Jiajia; Cui, Jian; Li, Bin; Wu, Shenshen; Yun, Jun; Aschner, Michael; Wa ... | R01ES007331, R01ES010563 | Environ Int (2022 Oct) | 36041244 | 2022 |
Probiotics and the Treatment of Parkinson's Disease: An Update. | Mirzaei, Hamed; Sedighi, Saman; Kouchaki, Ebrahim; Barati, Erfaneh; Dadgostar, Ehsan; Aschner, ... | R01ES007331, R01ES010563 | Cell Mol Neurobiol (2022 Nov) | 34283340 | 2022 |
Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1. | Chen, Liping; Guo, Ping; Li, Wenxue; Jiang, Xinhang; Zhao, Qun; Li, Daochuan; Wang, Qing; Xia ... | R01ES007331, R01ES010563 | J Biol Chem (2022 May) | 35405096 | 2022 |
Sex-dependent metal accumulation and immunoexpression of Hsp70 and Nrf2 in rats' brain following man ... | Ijomone, Omamuyovwi M; Iroegbu, Joy D; Morcillo, Patricia; Ayodele, Akinyemi J; Ijomone, Olayem ... | R01ES007331, R01ES010563 | Environ Toxicol (2022 Sep) | 35596948 | 2022 |
Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic ... | Zhang, Rui; Chen, Shen; Chen, Liping; Ye, Lizhu; Jiang, Yue; Peng, Hui; Guo, Zhanyu; Li, Mia ... | R01ES007331, R01ES010563 | Part Fibre Toxicol (2022 Jun 23) | 35739565 | 2022 |
Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressi ... | Li, Zhao-Cong; Wang, Lei-Lei; Zhao, Yue-Song; Peng, Dong-Jie; Chen, Jing; Jiang, Si-Yang; Zhao ... | R01ES007331, R01ES010563 | Ecotoxicol Environ Saf (2022 Aug) | 36068756 | 2022 |
Thallium Induces Antiproliferative and Cytotoxic Activity in Glioblastoma C6 and U373 Cell Cultures ... | Rangel-López, Edgar; Robles-Bañuelos, Benjamín; Guadiana-Ramírez, Natalia; Alvarez-Garduño, Vale ... | R01ES010563 | Neurotox Res (2022 Jun) | 35476314 | 2022 |
Toxic metals that interact with thiol groups and alteration in insect behavior. | Oliveira, Cláudia S; Nogara, Pablo A; Lima, Luíza S; Galiciolli, Maria Ea; Souza, Júlia V; Asch ... | R01ES007331, R01ES010563 | Curr Opin Insect Sci (2022 Aug) | 35462063 | 2022 |
3,3'-diindolylmethane exerts antiproliferation and apoptosis induction by TRAF2-p38 axis in gastric ... | Ye, Yang; Ye, Fen; Li, Xue; Yang, Qi; Zhou, Jianwei; Xu, Wenrong; Aschner, Michael; Lu, Rong ... | R01ES007331, R01ES010563 | Anticancer Drugs (2021 Feb 01) | 33315588 | 2021 |
A bistable, multiport valve enables microformulators creating microclinical analyzers that reveal ab ... | Miller, Dusty R; Schaffer, David K; Neely, M Diana; McClain, Ethan S; Travis, Adam R; Block 3rd ... | R01ES007331, R01ES010563, T32ES007028 | Sens Actuators B Chem (2021 Aug 15) | 34092923 | 2021 |
A potential role for zinc in restless legs syndrome. | Chen, Pan; Bornhorst, Julia; Patton, Stephanie; Bagai, Kanika; Nitin, Rachana; Miah, Mahfuzur; ... | R01ES007331, R01ES010563 | Sleep (2021 Apr 09) | 33175142 | 2021 |
An updated systematic review on the association between Cd exposure, blood pressure and hypertension ... | Martins, Airton C; Almeida Lopes, Ana Carolina B; Urbano, Mariana R; Carvalho, Maria de Fatima H ... | R01ES007331, R01ES010563 | Ecotoxicol Environ Saf (2021 Jan 15) | 33396156 | 2021 |
Application of Fluorescence Microscopy and Behavioral Assays to Demonstrating Neuronal Connectomes a ... | Ijomone, Omamuyovwi M; Gubert, Priscila; Okoh, Comfort O A; Varão, Alexandre M; Amara, Leandro ... | R01ES007331, R01ES010563 | Neuromethods (2021) | 34754139 | 2021 |
Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamaterg ... | Limana da Silveira, Tássia; Lopes Machado, Marina; Bicca Obetine Baptista, Fabiane; Farina Gonçal ... | R01ES007331, R01ES010563 | Brain Res Bull (2021 10) | 34271120 | 2021 |
Commonalities between Copper Neurotoxicity and Alzheimer's Disease. | Patel, Roshni; Aschner, Michael | R01ES007331, R01ES010563 | Toxics (2021 Jan 07) | 33430181 | 2021 |
Conjugates of desferrioxamine and aromatic amines improve markers of iron-dependent neurotoxicity. | Carvalho, Rodrigo R V; Peres, Tanara V; Liria, Cleber W; Machini, M Teresa; Aschner, Michael; E ... | R01ES007331, R01ES010563 | Biometals (2021 04) | 33389339 | 2021 |
Copper, Iron, Selenium and Lipo-Glycemic Dysmetabolism in Alzheimer's Disease. | Aaseth, Jan; Skalny, Anatoly V; Roos, Per M; Alexander, Jan; Aschner, Michael; Tinkov, Alexey ... | R01ES007331, R01ES010563 | Int J Mol Sci (2021 Aug 31) | 34502369 | 2021 |
Corrigendum to "Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory in ... | Skalny, Anatoly V; Lima, Thania Rios Rossi; Ke, Tao; Zhou, Ji-Chang; Bornhorst, Julia; Alekseen ... | R01ES007331, R01ES010563 | Food Chem Toxicol (2021 Mar) | 33500155 | 2021 |
Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity. | Morcillo, Patricia; Cordero, Hector; Ijomone, Omamuyovwi M; Ayodele, Akinyemi; Bornhorst, Julia ... | R01ES010563 | Mol Neurobiol (2021 Jul) | 33666854 | 2021 |
Diterpene glycosides from Holothuria scabra exert the α-synuclein degradation and neuroprotection ag ... | Chalorak, Pawanrat; Sornkaew, Nilubon; Manohong, Preeyanuch; Niamnont, Nakorn; Malaiwong, Nawap ... | R01ES007331, R01ES010563 | J Ethnopharmacol (2021 Oct 28) | 34147616 | 2021 |
Endocrine-disrupting activity of mancozeb. | Skalny, Anatoly; Aschner, Michael; Paoliello, Monica; Santamaria, Abel; Nikitina, Natalia; Rejn ... | R01ES010563 | Arh Farm (Belgr) (2021) | 35990020 | 2021 |
Endothelial Dysfunction Induced by Cadmium and Mercury and its Relationship to Hypertension. | Martins, Airton C; Santos, Alessanda A D; Lopes, Ana C B A; Skalny, Anatoly V; Aschner, Michael ... | R01ES007331, R01ES010563 | Curr Hypertens Rev (2021) | 33475076 | 2021 |
Evaluating the risk of manganese-induced neurotoxicity of parenteral nutrition: review of the curren ... | Martins Jr, Airton C; Ruella Oliveira, Silvana; Barbosa Jr, Fernando; Tinkov, Alexey A; V Skalny ... | R01ES007331, R01ES010563, R01ES031282 | Expert Opin Drug Metab Toxicol (2021 May) | 33620266 | 2021 |
Gut Microbiota as a Potential Player in Mn-Induced Neurotoxicity. | Tinkov, Alexey A; Martins, Airton C; Avila, Daiana Silva; Gritsenko, Victor A; Skalny, Anatoly ... | R01ES010563, R01ES031282 | Biomolecules (2021 Aug 31) | 34572505 | 2021 |
Haloperidol Interactions with the dop-3 Receptor in Caenorhabditis elegans. | Krum, Bárbara Nunes; Martins Jr, Airton C; Queirós, Libânia; Ferrer, Beatriz; Milne, Ginger L; ... | R01ES007331, R01ES010563 | Mol Neurobiol (2021 Jan) | 32935232 | 2021 |
HER2-specific chimeric antigen receptor-T cells for targeted therapy of metastatic colorectal cancer ... | Xu, Jie; Meng, Qingtao; Sun, Hao; Zhang, Xinwei; Yun, Jun; Li, Bin; Wu, Shenshen; Li, Xiaobo ... | R01ES007331, R01ES010563 | Cell Death Dis (2021 Nov 27) | 34839348 | 2021 |
Hypoxia-Inducible Exosomes Facilitate Liver-Tropic Premetastatic Niche in Colorectal Cancer. | Sun, Hao; Meng, Qingtao; Shi, Chengyu; Yang, Hongbao; Li, Xiaobo; Wu, Shenshen; Familiari, Gi ... | R01ES007331, R01ES010563 | Hepatology (2021 11) | 34110633 | 2021 |
Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in ... | Horning, Kyle J; Tang, Xueqi; Thomas, Morgan G; Aschner, Michael; Bowman, Aaron B | R01ES010563, T32ES007028 | Molecules (2021 Feb 22) | 33671818 | 2021 |
Impact of environmental toxicants on p38- and ERK-MAPK signaling pathways in the central nervous sys ... | Ijomone, Omamuyovwi M; Iroegbu, Joy D; Aschner, Michael; Bornhorst, Julia | R01ES007331, R01ES010563 | Neurotoxicology (2021 Sep) | 34389354 | 2021 |
In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabol ... | Nogara, Pablo Andrei; Omage, Folorunsho Bright; Bolzan, Gustavo Roni; Delgado, Cássia Pereira; A ... | R01ES007331, R01ES010563 | Mol Inform (2021 Aug) | 34018687 | 2021 |
Intercellular transfer of mitochondria via tunneling nanotubes protects against cobalt nanoparticle- ... | Zheng, Fuli; Luo, Zhousong; Lin, Xinpei; Wang, Wei; Aschner, Michael; Cai, Ping; Wang, Yuan-L ... | R01ES007331, R01ES010563 | Nanotoxicology (2021 Dec) | 35077651 | 2021 |
lncRNA TUG1 as a ceRNA promotes PM exposure-induced airway hyper-reactivity. | Li, Bin; Huang, Nannan; Wei, Shengnan; Xv, Jie; Meng, Qingtao; Aschner, Michael; Li, Xiaobo; ... | R01ES007331, R01ES010563 | J Hazard Mater (2021 08 15) | 34492818 | 2021 |
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate ... | Rizor, Asha; Pajarillo, Edward; Nyarko-Danquah, Ivan; Digman, Alexis; Mooneyham, Leyah; Son, D ... | R01ES010563, R01ES031282 | Neurotoxicology (2021 09) | 34310962 | 2021 |
Measurement of the Effects of Metals on Taxis-to-Food Behavior in Caenorhabditis elegans. | Queirós, Libânia; Monteiro, Luana; Marques, Carlos; Pereira, Joana L; Gonçalves, Fernando J M; ... | R01ES007331, R01ES010563 | Curr Protoc (2021 May) | 33974358 | 2021 |
Mechanisms of Metal-Induced Mitochondrial Dysfunction in Neurological Disorders. | Cheng, Hong; Yang, Bobo; Ke, Tao; Li, Shaojun; Yang, Xiaobo; Aschner, Michael; Chen, Pan | R01ES007331, R01ES010563 | Toxics (2021 Jun 17) | 34204190 | 2021 |
Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies ... | Skalny, Anatoly V; Aschner, Michael; Jiang, Yueming; Gluhcheva, Yordanka G; Tizabi, Yousef; Lob ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2021) | 34263089 | 2021 |
MOLECULAR MECHANISMS OF LEAD NEUROTOXICITY. | Virgolini, Miriam B; Aschner, Michael | R01ES007331, R01ES010563 | Adv Neurotoxicol (2021) | 34263090 | 2021 |
Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update. | Tinkov, Alexey A; Paoliello, Monica M B; Mazilina, Aksana N; Skalny, Anatoly V; Martins, Airton ... | R01ES010563 | Int J Mol Sci (2021 Apr 28) | 33925013 | 2021 |
Multibiomarker approach to assess the magnitude of occupational exposure and effects induced by a mi ... | Lopes de Andrade, V; Serrazina, D; Mateus, M L; Batoréu, C; Aschner, M; Marreilha Dos Santos, ... | R01ES007331, R01ES010563 | Toxicol Appl Pharmacol (2021 Oct 15) | 34437931 | 2021 |
Neurotoxicity mechanisms of manganese in the central nervous system. | Pajarillo, Edward; Nyarko-Danquah, Ivan; Adinew, Getinet; Rizor, Asha; Aschner, Michael; Lee, ... | R01ES007331, R01ES010563, R01ES031282 | Adv Neurotoxicol (2021) | 34263091 | 2021 |
NEUROTOXICITY OF METAL MIXTURES. | Lopes de Andrade, Vanda; Marreilha Dos Santos, Ana Paula; Aschner, Michael | R01ES007331, R01ES010563 | Adv Neurotoxicol (2021) | 34263093 | 2021 |
New epigenetic players in stroke pathogenesis: From non-coding RNAs to exosomal non-coding RNAs. | Mahjoubin-Tehran, Maryam; Rezaei, Samaneh; Jesmani, Amin; Birang, Nafise; Morshedi, Korosh; Kha ... | R01ES007331, R01ES010563 | Biomed Pharmacother (2021 Aug) | 34044272 | 2021 |
New insights on mechanisms underlying methylmercury-induced and manganese-induced neurotoxicity. | Martins, Airton C; Ke, Tao; Bowman, Aaron B; Aschner, Michael | R01ES007331, R01ES010563 | Curr Opin Toxicol (2021 Mar) | 33898886 | 2021 |
Novel Pharmacotherapies in Parkinson's Disease. | Tizabi, Yousef; Getachew, Bruk; Aschner, Michael | R01ES007331, R01ES010563 | Neurotox Res (2021 Aug) | 34003454 | 2021 |
Nutritive Manganese and Zinc Overdosing in Aging C. elegans Result in a Metallothionein-Mediated Alt ... | Baesler, Jessica; Michaelis, Vivien; Stiboller, Michael; Haase, Hajo; Aschner, Michael; Schwerd ... | R01ES007331, R01ES010563 | Mol Nutr Food Res (2021 Apr) | 33641237 | 2021 |
On the Biomedical Properties of Endocannabinoid Degradation and Reuptake Inhibitors: Pre-clinical an ... | Paredes-Ruiz, Karen Jaqueline; Chavira-Ramos, Karla; Orozco-Morales, Mario; Karasu, Cimen; Tinko ... | R01ES010563 | Neurotox Res (2021 Dec) | 34741755 | 2021 |
Overview of Chemotaxis Behavior Assays in Caenorhabditis elegans. | Queirós, Libânia; Marques, Carlos; Pereira, Joana L; Gonçalves, Fernando J M; Aschner, Michael; ... | R01ES007331, R01ES010563 | Curr Protoc (2021 May) | 33974354 | 2021 |
Pain Perception and Management: Where do We Stand? | Afridi, Bilal; Khan, Haroon; Akkol, Esra K; Aschner, Michael | R01ES007331, R01ES010563 | Curr Mol Pharmacol (2021) | 32525788 | 2021 |
Perturbation of Specific Signaling Pathways Is Involved in Initiation of Mouse Liver Fibrosis. | Chen, Liping; Guo, Ping; Li, Wenxue; Fang, Fei; Zhu, Wei; Fan, Junling; Wang, Fangping; Gao, ... | R01ES007331, R01ES010563 | Hepatology (2021 04) | 32654205 | 2021 |
Perturbed MAPK signaling in ASD: Impact of metal neurotoxicity. | Aluko, Oritoke M; Lawal, Saheed A; Ijomone, Omamuyovwi M; Aschner, Michael | R01ES007331, R01ES010563 | Curr Opin Toxicol (2021 Jun) | 34263087 | 2021 |
Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Ce ... | Elmazoglu, Zubeyir; Kayhan, Handan; Santamaría, Abel; Rangel-López, Edgar; Uğur, Pelin Kelicen; ... | R01ES007331, R01ES010563 | Neurochem Res (2021 Dec) | 34432181 | 2021 |
Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation ... | Shi, Wei; Fang, Yuanyuan; Jiang, Yueming; Jiang, Siyang; Li, Yu; Li, Wentao; Xu, Mingpeng; As ... | R01ES007331, R01ES010563 | Bioengineered (2021 12) | 34304701 | 2021 |
Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat ... | Elmazoglu, Zubeyir; Prnova, Marta Soltesova; Stefek, Milan; Ceylan, Asli F; Aschner, Michael; R ... | R01ES010563 | Neurotox Res (2021 Jun) | 33713301 | 2021 |
Protective Effects of Sodium Para-aminosalicylic Acid on Manganese-Induced Damage in Rat Pancreas. | Zhu, Xiaojuan; Xie, Bingyan; Liang, Dianyin; Qin, Wenxia; Zhao, Lin; Deng, Yue; Wen, Pingjing ... | R01ES007331, R01ES010563 | Biol Trace Elem Res (2021 Oct) | 33405079 | 2021 |
Review of the mechanism underlying mefloquine-induced neurotoxicity. | Martins, Airton C; Paoliello, Monica M B; Docea, Anca O; Santamaria, Abel; Tinkov, Alexey A; Sk ... | R01ES007331, R01ES010563 | Crit Rev Toxicol (2021 03) | 33905310 | 2021 |
S-allylcysteine induces cytotoxic effects in two human lung cancer cell lines via induction of oxida ... | Orozco-Morales, Mario; Hernández-Pedro, Norma Yanet; Barrios-Bernal, Pedro; Arrieta, Oscar; Ruiz ... | R01ES010563 | Anticancer Drugs (2021 Feb 01) | 33136700 | 2021 |
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity. | Tinkov, Alexey A; Nguyen, Thuy T; Santamaria, Abel; Bowman, Aaron B; Buha Djordjevic, Aleksandr ... | R01ES007331, R01ES010563 | Arch Toxicol (2021 07) | 34028595 | 2021 |
Social injustice in environmental health: A call for fortitude. | Aschner, Michael; Paoliello, Monica M B; Tsatsakis, Aristides; Bowman, Aaron B; Dorea, Jose G; ... | R01ES007331, R01ES010563 | Environ Res (2021 03) | 33373610 | 2021 |
Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells vi ... | Fang, Yuanyuan; Peng, Dongjie; Liang, Yuan; Lu, Lili; Li, Junyan; Zhao, Lin; Ou, Shiyan; Li, ... | R01ES010563 | Biol Trace Elem Res (2021 Sep) | 33156491 | 2021 |
The Effect of Lead Exposure on Autism Development. | Goel, Aanya; Aschner, Michael | R01ES007331, R01ES010563 | Int J Mol Sci (2021 Feb 06) | 33561959 | 2021 |
The Endocannabinoid System in Caenorhabditis elegans. | Estrada-Valencia, Rubén; de Lima, María Eduarda; Colonnello, Aline; Rangel-López, Edgar; Saraiva ... | R01ES007331, R01ES010563 | Rev Physiol Biochem Pharmacol (2021 Aug 17) | 34401955 | 2021 |
The Impact of Environmental Factors on Monogenic Mendelian Diseases. | Tukker, Anke M; Royal, Charmaine D; Bowman, Aaron B; McAllister, Kimberly A | R01ES010563 | Toxicol Sci (2021 Apr 27) | 33677604 | 2021 |
Therapeutic potential of alkaloids in autoimmune diseases: Promising candidates for clinical trials. | Khan, Haroon; Ullah, Hammad; Khattak, Sumaira; Aschner, Michael; Aguilar, Cristobal N; Halimi, ... | R01ES007331, R01ES010563 | Phytother Res (2021 Jan) | 32667693 | 2021 |
Therapeutic potential of marine peptides in glioblastoma: Mechanistic insights. | Ahmed, Salman; Hasan, Muhammad Mohtasheemul; Aschner, Michael; Mirzaei, Hamed; Alam, Waqas; Muk ... | R01ES010563 | Cell Signal (2021 11) | 34487816 | 2021 |
Whole body potassium as a biomarker for potassium uptake using a mouse model. | Tabbassum, Sana; Cheng, Pinjing; Yanko, Frank M; Balachandran, Rekha; Aschner, Michael; Bowman, ... | R01ES007331, R01ES010563 | Sci Rep (2021 Mar 18) | 33737537 | 2021 |
Zinc. | Skalny, Anatoly V; Aschner, Michael; Tinkov, Alexey A | R01ES007331, R01ES010563 | Adv Food Nutr Res (2021) | 34112355 | 2021 |
A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens. | Juttukonda, Lillian J; Beavers, William N; Unsihuay, Daisy; Kim, Kwangho; Pishchany, Gleb; Horn ... | R01ES010563, T32ES007028 | mBio (2020 10 27) | 33109764 | 2020 |
Are we rushing too much? | Aschner, Michael | R01ES007331, R01ES010563 | Food Chem Toxicol (2020 Sep) | 32640328 | 2020 |
Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitiga ... | Pajarillo, Edward; Johnson Jr, James; Rizor, Asha; Nyarko-Danquah, Ivan; Adinew, Getinet; Bornh ... | R01ES007331, R01ES010563, R01ES031282 | J Biol Chem (2020 Nov 13) | 32893191 | 2020 |
Brain manganese and the balance between essential roles and neurotoxicity. | Balachandran, Rekha C; Mukhopadhyay, Somshuvra; McBride, Danielle; Veevers, Jennifer; Harrison, ... | P30ES026529, R01ES010563, R01ES024812, R01ES031401 | J Biol Chem (2020 May 08) | 32188696 | 2020 |
Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies. | Varmazyari, Atefeh; Taghizadehghalehjoughi, Ali; Sevim, Cigdem; Baris, Ozlem; Eser, Gizem; Yild ... | R01ES007331, R01ES010563 | Toxicol Rep (2020) | 32489905 | 2020 |
Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by r ... | Li, Daochuan; Chen, Shen; Li, Qiong; Chen, Liping; Zhang, Haiyan; Li, Huiyao; Yu, Dianke; Zha ... | R01ES007331, R01ES010563 | Part Fibre Toxicol (2020 Jun 05) | 32503629 | 2020 |
Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation ... | Elmazoglu, Zubeyir; Rangel-López, Edgar; Medina-Campos, Omar Noel; Pedraza-Chaverri, José; Túnez ... | R01ES007331, R01ES010563 | Neurochem Int (2020 Nov) | 32781098 | 2020 |
Cephalic Neuronal Vesicle Formation is Developmentally Dependent and Modified by Methylmercury and s ... | Ke, Tao; Santamaria, Abel; Rocha, Joao B T; Tinkov, Alex; Bornhorst, Julia; Bowman, Aaron B; A ... | R01ES007331, R01ES010563 | Neurochem Res (2020 Dec) | 33037975 | 2020 |
Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caeno ... | Ke, Tao; Tsatsakis, Aristidis; Santamaría, Abel; Antunes Soare, Félix Alexandre; Tinkov, Alexey ... | R01ES007331, R01ES010563 | Neurotoxicology (2020 03) | 31935438 | 2020 |
Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis eleg ... | Colonnello, Aline; Aguilera-Portillo, Gabriela; Rubio-López, Leonardo C; Robles-Bañuelos, Benjam ... | R01ES007331, R01ES010563 | Neurotox Res (2020 Feb) | 31773641 | 2020 |
Differential susceptibility of PC12 and BRL cells and the regulatory role of HIF-1α signaling pathwa ... | Liu, Tingting; Gao, Qianqian; Yang, Bobo; Yin, Changsheng; Chang, Jie; Qian, Hai; Xing, Guang ... | R01ES007331, R01ES010563 | Toxicol Lett (2020 Oct 01) | 32461003 | 2020 |
Disparity in Risk Factor Severity for Early Childhood Blood Lead among Predominantly African-America ... | Yeter, Deniz; Banks, Ellen C; Aschner, Michael | R01ES007331, R01ES010563 | Int J Environ Res Public Health (2020 Feb 28) | 32121216 | 2020 |
Drp-1-Dependent Mitochondrial Fragmentation Contributes to Cobalt Chloride-Induced Toxicity in Caeno ... | Zheng, Fuli; Chen, Pan; Li, Huangyuan; Aschner, Michael | R01ES010563 | Toxicol Sci (2020 09 01) | 32617571 | 2020 |
Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunct ... | Zhang, Ziyan; Yan, Jingqi; Bowman, Aaron B; Bryan, Miles R; Singh, Rajat; Aschner, Michael | R01ES007331, R01ES010563 | Autophagy (2020 Aug) | 31690173 | 2020 |
Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposu ... | Ijomone, Omamuyovwi M; Olung, Nzube F; Akingbade, Grace T; Okoh, Comfort O A; Aschner, Michael | R01ES007331, R01ES010563 | J Trace Elem Med Biol (2020 Dec) | 32891009 | 2020 |
Epigenetic influence of environmentally neurotoxic metals. | Ijomone, Omamuyovwi M; Ijomone, Olayemi K; Iroegbu, Joy D; Ifenatuoha, Chibuzor W; Olung, Nzube ... | R01ES007331, R01ES010563 | Neurotoxicology (2020 Dec) | 32882300 | 2020 |
Generating Bacterial Foods in Toxicology Studies with Caenorhabditis elegans. | Ke, Tao; Santamaría, Abel; Tinkov, Alexey A; Bornhorst, Julia; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2020 06) | 32436649 | 2020 |
High throughput fluorimetric assessment of iron traffic and chelation in iron-overloaded Caenorhabdi ... | Espósito, Breno Pannia; Martins, Airton Cunha; de Carvalho, Rodrigo Rodrigues Victor; Aschner, M ... | R01ES007331, R01ES010563 | Biometals (2020 10) | 32979113 | 2020 |
Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and m ... | Pfalzer, Anna C; Wilcox, Jordyn M; Codreanu, Simona G; Totten, Melissa; Bichell, Terry J V; Hal ... | R01ES010563, T32ES007028 | Metallomics (2020 Jul 22) | 32421118 | 2020 |
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular ... | Horning, Kyle J; Joshi, Piyush; Nitin, Rachana; Balachandran, Rekha C; Yanko, Frank M; Kim, Kw ... | R01ES010563, T32ES007028 | J Biol Chem (2020 Mar 20) | 32047113 | 2020 |
Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity. | Taylor, Cherish A; Tuschl, Karin; Nicolai, Merle M; Bornhorst, Julia; Gubert, Priscila; Varão, ... | R01ES007331, R01ES010563, R01ES024812 | J Nutr (2020 Jun 01) | 32211802 | 2020 |
Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms. | Nyarko-Danquah, Ivan; Pajarillo, Edward; Digman, Alexis; Soliman, Karam F A; Aschner, Michael; ... | R01ES007331, R01ES010563, R01ES031282 | Molecules (2020 Dec 12) | 33322668 | 2020 |
Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntin ... | Bryan, Miles R; Nordham, Kristen D; Rose, Daniel I R; O'Brien, Michael T; Joshi, Piyush; Foshag ... | R01ES010563, T32ES007028 | Mol Neurobiol (2020 Mar) | 31797328 | 2020 |
Manganese-induced Mitochondrial Dysfunction Is Not Detectable at Exposures Below the Acute Cytotoxic ... | Warren, Emily B; Bryan, Miles R; Morcillo, Patricia; Hardeman, Keisha N; Aschner, Michael; Bowm ... | R01ES010563 | Toxicol Sci (2020 Aug 01) | 32492146 | 2020 |
Manganese-induced neurodegenerative diseases and possible therapeutic approaches. | Martins Jr, Airton C; Gubert, Priscila; Villas Boas, Gustavo R; Meirelles Paes, Marina; Santamar ... | R01ES007331, R01ES010563 | Expert Rev Neurother (2020 11) | 32799578 | 2020 |
Metal environmental contamination within different human exposure context- specific and non-specific ... | de Andrade, Vanda Lopes; Cota, Madalena; Serrazina, Daniela; Mateus, Maria Luisa; Aschner, Mich ... | R01ES007331, R01ES010563 | Toxicol Lett (2020 May 15) | 31935480 | 2020 |
Metal-induced neurotoxicity in a RAGE-expressing C. elegans model. | Lawes, Michael; Pinkas, Adi; Frohlich, Bailey A; Iroegbu, Joy D; Ijomone, Omamuyovwi M; Aschner ... | R01ES007331, R01ES010563 | Neurotoxicology (2020 09) | 32621835 | 2020 |
Neurotoxicity of e-cigarettes. | Ruszkiewicz, Joanna A; Zhang, Ziyan; Gonçalves, Filipe Marques; Tizabi, Yousef; Zelikoff, Judit ... | R01ES007331, R01ES010563 | Food Chem Toxicol (2020 Apr) | 32145355 | 2020 |
Nicotine and the nicotinic cholinergic system in COVID-19. | Tizabi, Yousef; Getachew, Bruk; Copeland, Robert L; Aschner, Michael | R01ES007331, R01ES010563 | FEBS J (2020 09) | 32790936 | 2020 |
Oleamide Induces Cell Death in Glioblastoma RG2 Cells by a Cannabinoid Receptor-Independent Mechanis ... | Torres-Román, Ana Laura; García-Hernández, Victor Manuel; Rangel-López, Edgar; Ruiz-García, Erik ... | R01ES010563 | Neurotox Res (2020 Dec) | 32930995 | 2020 |
Redox toxicology of environmental chemicals causing oxidative stress. | Zheng, Fuli; Gonçalves, Filipe Marques; Abiko, Yumi; Li, Huangyuan; Kumagai, Yoshito; Aschner, ... | R01ES007331, R01ES010563 | Redox Biol (2020 Jul) | 32336668 | 2020 |
S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidativ ... | Reyes-Soto, Carolina Y; Rangel-López, Edgar; Galván-Arzate, Sonia; Colín-González, Ana Laura; Si ... | R01ES010563 | Neurotox Res (2020 Dec) | 32813208 | 2020 |
Sulfhydryl groups as targets of mercury toxicity. | Ajsuvakova, Olga P; Tinkov, Alexey A; Aschner, Michael; Rocha, João B T; Michalke, Bernhard; Sk ... | R01ES007331, R01ES010563 | Coord Chem Rev (2020 Aug 15) | 32905350 | 2020 |
Thallium Toxicity in Caenorhabditis elegans: Involvement of the SKN-1 Pathway and Protection by S-Al ... | Hurtado-Díaz, María Ester; Estrada-Valencia, Rubén; Rangel-López, Edgar; Maya-López, Marisol; Co ... | R01ES010563 | Neurotox Res (2020 Aug) | 32468422 | 2020 |
The effects of manganese overexposure on brain health. | Miah, Mahfuzur R; Ijomone, Omamuyovwi M; Okoh, Comfort O A; Ijomone, Olayemi K; Akingbade, Grac ... | R01ES007331, R01ES010563 | Neurochem Int (2020 May) | 31972215 | 2020 |
The impact of manganese on neurotransmitter systems. | Soares, Ana Thalita Gonçalves; Silva, Aline de Castro; Tinkov, Alexey A; Khan, Haroon; Santamarí ... | R01ES007331, R01ES010563 | J Trace Elem Med Biol (2020 May 20) | 32480053 | 2020 |
The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Ne ... | Ke, Tao; Santamaria, Abel; Rocha, Joao B T; Tinkov, Alexey A; Lu, Rongzhu; Bowman, Aaron B; As ... | R01ES007331, R01ES010563 | Neurotox Res (2020 Oct) | 32725544 | 2020 |
The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans. | Neumann, Catherine; Baesler, Jessica; Steffen, Gereon; Nicolai, Merle Marie; Zubel, Tabea; Asch ... | R01ES007331, R01ES010563 | J Trace Elem Med Biol (2020 Jan) | 31546209 | 2020 |
The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects ... | Pajarillo, Edward; Rizor, Asha; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563, R01ES031282 | J Biol Chem (2020 Mar 06) | 32001620 | 2020 |
Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious disease ... | Skalny, Anatoly V; Lima, Thania Rios Rossi; Ke, Tao; Zhou, Ji-Chang; Bornhorst, Julia; Alekseen ... | R01ES007331, R01ES010563 | Food Chem Toxicol (2020 Dec) | 33069759 | 2020 |
Transcriptomic and Proteomic Tools in the Study of Hg Toxicity: What Is Missing? | Oliveira, Cláudia S; Segatto, Ana L A; Nogara, Pablo A; Piccoli, Bruna C; Loreto, Élgion L S; A ... | R01ES007331, R01ES010563 | Front Genet (2020) | 32431728 | 2020 |
A review of the alleged health hazards of monosodium glutamate. | Zanfirescu, Anca; Ungurianu, Anca; Tsatsakis, Aristides M; Nițulescu, George M; Kouretas, Demet ... | R01ES007331, R01ES010563 | Compr Rev Food Sci Food Saf (2019 Jul) | 31920467 | 2019 |
Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell l ... | Bryan, Miles R; O'Brien, Michael T; Nordham, Kristen D; Rose, Daniel I R; Foshage, Audra M; Jos ... | R01ES010563, T32ES007028 | Hum Mol Genet (2019 11 15) | 31600787 | 2019 |
Bacteria affect Caenorhabditis elegans responses to MeHg toxicity. | Ke, Tao; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2019 12) | 31542475 | 2019 |
Brain diseases in changing climate. | Ruszkiewicz, Joanna A; Tinkov, Alexey A; Skalny, Anatoly V; Siokas, Vasileios; Dardiotis, Efthi ... | R01ES007331, R01ES010563 | Environ Res (2019 10) | 31416010 | 2019 |
Caenorhabditis elegans and its applicability to studies on restless legs syndrome. | Chen, Pan; Ijomone, Omamuyovwi Meashack; Lee, Kun He; Aschner, Michael | R01ES007331, R01ES010563 | Adv Pharmacol (2019) | 31229169 | 2019 |
Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applicati ... | Queirós, L; Pereira, J L; Gonçalves, F J M; Pacheco, M; Aschner, M; Pereira, P | R01ES007331, R01ES010563 | Crit Rev Toxicol (2019 May) | 31268799 | 2019 |
Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution. | Li, Xiaobo; Cui, Jian; Yang, Hongbao; Sun, Hao; Lu, Runze; Gao, Na; Meng, Qingtao; Wu, Shens ... | R01ES007331, R01ES010563 | Adv Sci (Weinh) (2019 Jun 05) | 31179224 | 2019 |
Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, ch ... | Schetinger, Maria Rosa Chitolina; Peres, Tanara V; Arantes, Letícia P; Carvalho, Fabiano; Dressl ... | R01ES007331, R01ES010563 | Toxicology (2019 Jan 01) | 30336192 | 2019 |
Editorial: Sex and Gene-Dependent Neurotoxicity. | Ruszkiewicz, Joanna A; Aschner, Michael | R01ES007331, R01ES010563 | Front Genet (2019) | 30891065 | 2019 |
Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barr ... | Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James ... | R01ES010563 | J Cereb Blood Flow Metab (2019 11) | 29911470 | 2019 |
Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay. | Farina, Marcelo; Aschner, Michael | R01ES007331, R01ES010563 | Biochim Biophys Acta Gen Subj (2019 12) | 30659883 | 2019 |
Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmer ... | Prince, Lisa M; Aschner, Michael; Bowman, Aaron B | R01ES007331, R01ES010563 | Biochim Biophys Acta Gen Subj (2019 12) | 30742955 | 2019 |
Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuro ... | Joshi, Piyush; Bodnya, Caroline; Ilieva, Ilyana; Neely, M Diana; Aschner, Michael; Bowman, Aar ... | R01ES010563 | Neurotoxicology (2019 12) | 31545971 | 2019 |
Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment. | Chen, Pan; Totten, Melissa; Zhang, Ziyan; Bucinca, Hana; Erikson, Keith; Santamaría, Abel; Bow ... | R01ES007331, R01ES010563 | Expert Rev Neurother (2019 Mar) | 30759034 | 2019 |
LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia. | Kim, Judong; Pajarillo, Edward; Rizor, Asha; Son, Deok-Soo; Lee, Jayden; Aschner, Michael; Lee ... | R01ES010563, R01ES031282 | PLoS One (2019) | 30645642 | 2019 |
MALAT1 rs664589 Polymorphism Inhibits Binding to miR-194-5p, Contributing to Colorectal Cancer Risk, ... | Wu, Shenshen; Sun, Hao; Wang, Yajie; Yang, Xi; Meng, Qingtao; Yang, Hongbao; Zhu, Haitao; Tan ... | R01ES007331, R01ES010563 | Cancer Res (2019 10 15) | 31311811 | 2019 |
Manganese: Its Role in Disease and Health. | Erikson, Keith M; Aschner, Michael | R01ES007331, R01ES010563 | Met Ions Life Sci (2019 Jan 14) | 30855111 | 2019 |
Methylmercury Epigenetics. | Culbreth, Megan; Aschner, Michael | R01ES007331, R01ES010563, T32ES007026 | Toxics (2019 Nov 09) | 31717489 | 2019 |
Natural Products in the Promotion of Healthspan and Longevity. | Niso-Santano, Mireia; González-Polo, Rosa A; Paredes-Barquero, Marta; Fuentes, José M; Aschner, ... | R01ES007331, R01ES010563 | Clin Pharmacol Transl Med (2019) | 31363716 | 2019 |
New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease. | Martins Jr, Airton Cunha; Morcillo, Patricia; Ijomone, Omamuyovwi Meashack; Venkataramani, Vivek ... | R01ES007331, R01ES010563 | Int J Environ Res Public Health (2019 Sep 22) | 31546716 | 2019 |
Organotins in obesity and associated metabolic disturbances. | Tinkov, Alexey A; Ajsuvakova, Olga P; Skalnaya, Margarita G; Skalny, Anatoly V; Aschner, Michae ... | R01ES007331, R01ES010563 | J Inorg Biochem (2019 02) | 30458368 | 2019 |
Overview of the effects of chemical mixtures with endocrine disrupting activity in the context of re ... | Margina, Denisa; Nițulescu, George Mihai; Ungurianu, Anca; Mesnage, Robin; Goumenou, Marina; Sa ... | R01ES007331, R01ES010563 | World Acad Sci J (2019 Jul) | 32346674 | 2019 |
Polyphenols in the treatment of autoimmune diseases. | Khan, Haroon; Sureda, Antoni; Belwal, Tarun; Çetinkaya, Sümeyra; Süntar, İpek; Tejada, Silvia; ... | R01ES007331, R01ES010563 | Autoimmun Rev (2019 Jul) | 31059841 | 2019 |
Post-translational modifications in MeHg-induced neurotoxicity. | Ke, Tao; Gonçalves, Filipe Marques; Gonçalves, Cinara Ludvig; Dos Santos, Alessandra Antunes; Ro ... | R01ES007331, R01ES010563 | Biochim Biophys Acta Mol Basis Dis (2019 08 01) | 30385410 | 2019 |
Role of Astrocytes in Manganese Neurotoxicity Revisited. | Ke, Tao; Sidoryk-Wegrzynowicz, Marta; Pajarillo, Edward; Rizor, Asha; Soares, Félix Alexandre A ... | R01ES007331, R01ES010563, R01ES031282 | Neurochem Res (2019 Nov) | 31571097 | 2019 |
Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease. | Ruszkiewicz, Joanna A; Miranda-Vizuete, Antonio; Tinkov, Alexey A; Skalnaya, Margarita G; Skalny ... | R01ES007331, R01ES010563 | J Mol Neurosci (2019 Feb) | 30604380 | 2019 |
Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity. | Ruszkiewicz, Joanna A; Teixeira de Macedo, Gabriel; Miranda-Vizuete, Antonio; Bowman, Aaron B; B ... | R01ES007331, R01ES010563 | Neurotox Res (2019 Jan) | 30155682 | 2019 |
Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo. | Peres, Tanara V; Horning, Kyle J; Bornhorst, Julia; Schwerdtle, Tanja; Bowman, Aaron B; Aschner ... | R01ES007331, R01ES010563 | Biol Trace Elem Res (2019 Mar) | 30267310 | 2019 |
The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential t ... | Pajarillo, Edward; Rizor, Asha; Lee, Jayden; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563, R01ES031282 | Neuropharmacology (2019 Dec 15) | 30851309 | 2019 |
The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potenti ... | Pajarillo, Edward; Rizor, Asha; Lee, Jayden; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563, R01ES031282 | Biochim Biophys Acta Mol Basis Dis (2019 Aug 01) | 30481588 | 2019 |
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems ... | Rohn, Isabelle; Raschke, Stefanie; Aschner, Michael; Tuck, Simon; Kuehnelt, Doris; Kipp, Anna; ... | R01ES007331, R01ES010563 | Mol Nutr Food Res (2019 May) | 30815971 | 2019 |
Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 p ... | Li, Shao-Jun; Chen, Pan; Peres, Tanara Vieira; Villahoz, Beatriz Ferrer; Zhang, Ziyan; Miah, M ... | R01ES007331, R01ES010563 | Neurotoxicology (2019 09) | 31381933 | 2019 |
Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans. | Baesler, Jessica; Kopp, Johannes F; Pohl, Gabriele; Aschner, Michael; Haase, Hajo; Schwerdtle, ... | R01ES007331, R01ES010563 | J Trace Elem Med Biol (2019 Sep) | 31345364 | 2019 |
17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity. | Pajarillo, Edward; Johnson Jr, James; Kim, Judong; Karki, Pratap; Son, Deok-Soo; Aschner, Mich ... | R01ES010563 | Neurotoxicology (2018 03) | 29183790 | 2018 |
Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK ... | Karki, Pratap; Hong, Peter; Johnson Jr, James; Pajarillo, Edward; Son, Deok-Soo; Aschner, Mich ... | R01ES010563, R01ES031282 | Mol Neurobiol (2018 Jun) | 28812276 | 2018 |
Assessment of occupational exposures to multiple metals with urinary porphyrin profiles. | de Andrade, V Lopes; Mateus, M L; Aschner, M; Dos Santos, Ap Marreilha | R01ES007331, R01ES010563 | J Integr OMICS (2018 Jun) | 30666282 | 2018 |
Association of exposure to manganese and iron with striatal and thalamic GABA and other neurometabol ... | Casjens, Swaantje; Dydak, Urike; Dharmadhikari, Shalmali; Lotz, Anne; Lehnert, Martin; Quetsche ... | R01ES010563 | Neurotoxicology (2018 Jan) | 28803850 | 2018 |
Biomarkers of exposure and effect in a working population exposed to lead, manganese and arsenic. | Serrazina, Daniela C; Lopes De Andrade, Vanda; Cota, Madalena; Mateus, Maria Luísa; Aschner, Mi ... | R01ES007331, R01ES010563 | J Toxicol Environ Health A (2018) | 30296394 | 2018 |
C. elegans as a model in developmental neurotoxicology. | Ruszkiewicz, Joanna A; Pinkas, Adi; Miah, Mahfuzur R; Weitz, Rebecca L; Lawes, Michael J A; Aki ... | R01ES007331, R01ES010563 | Toxicol Appl Pharmacol (2018 09 01) | 29550512 | 2018 |
C. elegans-An Emerging Model to Study Metal-Induced RAGE-Related Pathologies. | Pinkas, Adi; Cunha Martins Jr, Airton; Aschner, Michael | R01ES007331, R01ES010563 | Int J Environ Res Public Health (2018 Jul 04) | 29973513 | 2018 |
DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1 ... | Wu, Shenshen; Meng, Qingtao; Zhang, Chengcheng; Sun, Hao; Lu, Runze; Gao, Na; Yang, Hongbao; ... | R01ES007331, R01ES010563 | Int J Cancer (2018 Jul 15) | 29446085 | 2018 |
Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation. | Unoki, Takamitsu; Akiyama, Masahiro; Kumagai, Yoshito; Gonçalves, Filipe Marques; Farina, Marce ... | R01ES007331, R01ES010563 | Front Genet (2018) | 30271424 | 2018 |
MPO Promoter Polymorphism rs2333227 Enhances Malignant Phenotypes of Colorectal Cancer by Altering t ... | Meng, Qingtao; Wu, Shenshen; Wang, Yajie; Xu, Jin; Sun, Hao; Lu, Runze; Gao, Na; Yang, Hongb ... | R01ES007331, R01ES010563 | Cancer Res (2018 May 15) | 29540402 | 2018 |
Neurodevelopmental Effects of Mercury. | Oliveira, Cláudia S; Nogara, Pablo A; Ardisson-Araújo, Daniel M P; Aschner, Michael; Rocha, Joã ... | R01ES007331, R01ES010563 | Adv Neurotoxicol (2018) | 32346667 | 2018 |
Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier. | Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James ... | R01ES010563 | PLoS One (2018) | 29889872 | 2018 |
Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell sign ... | Bryan, Miles R; Uhouse, Michael A; Nordham, Kristen D; Joshi, Piyush; Rose, Daniel I R; O'Brien ... | R01ES010563 | Neurotoxicology (2018 Jan) | 28780388 | 2018 |
Quinolinic acid and glutamatergic neurodegeneration in Caenorhabditis elegans. | da Silveira, Tássia Limana; Zamberlan, Daniele Coradine; Arantes, Leticia Priscilla; Machado, Ma ... | R01ES007331, R01ES010563 | Neurotoxicology (2018 07) | 29702159 | 2018 |
Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity. | Peres, Tanara V; Arantes, Leticia P; Miah, Mahfuzur R; Bornhorst, Julia; Schwerdtle, Tanja; Bow ... | R01ES007331, R01ES010563 | Neurotox Res (2018 Oct) | 29882004 | 2018 |
Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis ... | Rohn, Isabelle; Marschall, Talke Anu; Kroepfl, Nina; Jensen, Kenneth Bendix; Aschner, Michael; ... | R01ES007331, R01ES010563 | Metallomics (2018 06 20) | 29770420 | 2018 |
System-specific neurodegeneration following glucotoxicity in the C. elegans model. | Pinkas, Adi; Lawes, Michael; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2018 09) | 30036563 | 2018 |
Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutam ... | Johnson Jr, James; Pajarillo, Edward Alain B; Taka, Equar; Reams, Romonia; Son, Deok-Soo; Aschn ... | R01ES010563 | Neurotoxicology (2018 Jan) | 28610743 | 2018 |
Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomita ... | Johnson Jr, James; Pajarillo, Edward; Karki, Pratap; Kim, Judong; Son, Deok-Soo; Aschner, Mich ... | R01ES010563, R01ES031282 | Neurotoxicology (2018 Jul) | 29778792 | 2018 |
Accelerated differentiation of human induced pluripotent stem cells to blood-brain barrier endotheli ... | Hollmann, Emma K; Bailey, Amanda K; Potharazu, Archit V; Neely, M Diana; Bowman, Aaron B; Lippm ... | R01ES010563 | Fluids Barriers CNS (2017 Apr 13) | 28407791 | 2017 |
AGEs/RAGE-Related Neurodegeneration: daf-16 as a Mediator, Insulin as an Ameliorant, and C. elegans ... | Pinkas, Adi; Aschner, Michael | R01ES007331, R01ES010563 | Chem Res Toxicol (2017 Jan 17) | 27704837 | 2017 |
Associations between former exposure to manganese and olfaction in an elderly population: Results fr ... | Casjens, Swaantje; Pesch, Beate; Robens, Sibylle; Kendzia, Benjamin; Behrens, Thomas; Weiss, T ... | R01ES010563 | Neurotoxicology (2017 Jan) | 27865828 | 2017 |
Biomarkers of mercury toxicity: Past, present, and future trends. | Branco, Vasco; Caito, Sam; Farina, Marcelo; Teixeira da Rocha, João; Aschner, Michael; Carvalho ... | R01ES007331, R01ES010563 | J Toxicol Environ Health B Crit Rev (2017) | 28379072 | 2017 |
BXD recombinant inbred strains participate in social preference, anxiety and depression behaviors al ... | López-Granero, Caridad; Antunes Dos Santos, Alessandra; Ferrer, Beatriz; Culbreth, Megan; Chakra ... | R01ES007331, R01ES010563 | Psychoneuroendocrinology (2017 Jun) | 28324704 | 2017 |
Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease. | Di Pardo, Alba; Amico, Enrico; Basit, Abdul; Armirotti, Andrea; Joshi, Piyush; Neely, M Diana; ... | R01ES010563 | Sci Rep (2017 07 13) | 28706199 | 2017 |
Disease-Toxicant Interactions in Parkinson's Disease Neuropathology. | Kwakye, Gunnar F; McMinimy, Rachael A; Aschner, Michael | R01ES007331, R01ES010563 | Neurochem Res (2017 Jun) | 27613618 | 2017 |
From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Hu ... | Neely, M Diana; Davison, Carrie Ann; Aschner, Michael; Bowman, Aaron B | R01ES010563 | Toxicol Sci (2017 Oct 01) | 28962525 | 2017 |
Frontiers in Toxicogenomics in the Twenty-First Century-the Grand Challenge: To Understand How the G ... | Ruden, Douglas M; Gurdziel, Katherine; Aschner, Michael | R01ES007331, R01ES010563 | Front Genet (2017) | 29170679 | 2017 |
Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative ... | Bryan, Miles R; Bowman, Aaron B | R01ES010563 | Adv Neurobiol (2017) | 28889265 | 2017 |
Manganese Control of Glutamate Transporters' Gene Expression. | Lee, Eunsook; Karki, Pratap; Johnson Jr, James; Hong, Peter; Aschner, Michael | R01ES010563 | Adv Neurobiol (2017) | 28828603 | 2017 |
Metals and Circadian Rhythms. | Parmalee, Nancy L; Aschner, Michael | R01ES007331, R01ES010563 | Adv Neurotoxicol (2017) | 30729219 | 2017 |
Neuroprotective and Therapeutic Strategies for Manganese-Induced Neurotoxicity. | Marreilha Dos Santos, A P; Andrade, V; Aschner, M | R01ES007331, R01ES010563 | Clin Pharmacol Transl Med (2017) | 30854510 | 2017 |
Neurotoxic effect of active ingredients in sunscreen products, a contemporary review. | Ruszkiewicz, Joanna A; Pinkas, Adi; Ferrer, Beatriz; Peres, Tanara V; Tsatsakis, Aristides; Asc ... | R01ES007331, R01ES010563 | Toxicol Rep (2017) | 28959646 | 2017 |
Neurotoxicity of fragrance compounds: A review. | Pinkas, Adi; Gonçalves, Cinara Ludvig; Aschner, Michael | R01ES007331, R01ES010563 | Environ Res (2017 Oct) | 28683407 | 2017 |
Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixd ... | Pesch, Beate; Casjens, Swaantje; Weiss, Tobias; Kendzia, Benjamin; Arendt, Marina; Eisele, Lew ... | R01ES010563 | Ann Work Expo Health (2017 Nov 10) | 29136419 | 2017 |
Phenotypic Discordance in Siblings with Identical Compound Heterozygous PARK2 Mutations. | Isaacs, David; Claassen, Daniel; Bowman, Aaron B; Hedera, Peter | R01ES010563 | Brain Sci (2017 Jun 24) | 28672806 | 2017 |
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse mo ... | Bichell, Terry Jo V; Wegrzynowicz, Michal; Tipps, K Grace; Bradley, Emma M; Uhouse, Michael A; ... | R01ES010563, T32ES007028 | Biochim Biophys Acta Mol Basis Dis (2017 06) | 28213125 | 2017 |
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) poten ... | Aschner, Michael; Ceccatelli, Sandra; Daneshian, Mardas; Fritsche, Ellen; Hasiwa, Nina; Hartung ... | R01ES007331, R01ES010563, R01ES014901 | ALTEX (2017) | 27452664 | 2017 |
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease. | Pfalzer, Anna C; Bowman, Aaron B | R01ES010563, T32ES007028 | Curr Environ Health Rep (2017 Jun) | 28417441 | 2017 |
Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain bar ... | Liu, Xinqin; Su, Peng; Meng, Shanshan; Aschner, Michael; Cao, Yupeng; Luo, Wenjing; Zheng, Ga ... | R01ES007331, R01ES010563 | Int J Biol Sci (2017) | 29209140 | 2017 |
Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice throu ... | Li, Xiaobo; Yang, Hongbao; Wu, Shenshen; Meng, Qingtao; Sun, Hao; Lu, Runze; Cui, Jian; Zheng ... | R01ES007331, R01ES010563 | Part Fibre Toxicol (2017 Dec 12) | 29233151 | 2017 |
Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrog ... | Li, Xiaobo; Yang, Hongbao; Sun, Hao; Lu, Runze; Zhang, Chengcheng; Gao, Na; Meng, Qingtao; Wu ... | R01ES007331, R01ES010563 | Proc Natl Acad Sci U S A (2017 Nov 07) | 29078374 | 2017 |
The catecholaminergic neurotransmitter system in methylmercury-induced neurotoxicity. | Farina, Marcelo; Aschner, Michael; da Rocha, João Batista Teixeira | R01ES007331, R01ES010563 | Adv Neurotoxicol (2017) | 32346666 | 2017 |
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Mangane ... | Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; Dos Santos, Ap Marreilha | R01ES007331, R01ES010563 | EC Pharmacol Toxicol (2017) | 31633124 | 2017 |
Toxicology of Lead and Its Damage to Mammalian Organs. | Caito, Samuel; Lopes, Ana Carolina B Almeida; Paoliello, Monica M B; Aschner, Michael | R01ES007331, R01ES010563 | Met Ions Life Sci (2017 Apr 10) | 28731309 | 2017 |
Transcriptional Regulation of Human Transforming Growth Factor-α in Astrocytes. | Karki, Pratap; Johnson Jr, James; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563 | Mol Neurobiol (2017 03) | 26797516 | 2017 |
XRCC1 mediated the development of cervival cancer through a novel Sp1/Krox-20 swich. | Meng, Qingtao; Wang, Shizhi; Tang, Weiyan; Wu, Shenshen; Gao, Na; Zhang, Chengcheng; Cao, Xia ... | R01ES007331, R01ES010563 | Oncotarget (2017 Oct 17) | 29156789 | 2017 |
"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strate ... | Peres, Tanara V; Schettinger, Maria Rosa C; Chen, Pan; Carvalho, Fabiano; Avila, Daiana S; Bowm ... | R01ES010563 | BMC Pharmacol Toxicol (2016 Nov 04) | 27814772 | 2016 |
A Simple Light Stimulation of Caenorhabditis elegans. | Lee, Kun He; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2016 Feb 01) | 26828328 | 2016 |
Advanced Glycation End-Products and Their Receptors: Related Pathologies, Recent Therapeutic Strateg ... | Pinkas, Adi; Aschner, Michael | R01ES007331, R01ES010563 | Chem Res Toxicol (2016 May 16) | 27054356 | 2016 |
Autophagy in Neurodegenerative Diseases and Metal Neurotoxicity. | Zhang, Ziyan; Miah, Mahfuzur; Culbreth, Megan; Aschner, Michael | R01ES007331, R01ES010563 | Neurochem Res (2016 Feb) | 26869037 | 2016 |
Caenorhabditis elegans as a model system to study post-translational modifications of human transthy ... | Henze, Andrea; Homann, Thomas; Rohn, Isabelle; Aschner, Michael; Link, Christopher D; Kleuser, ... | R01ES007331, R01ES010563 | Sci Rep (2016 Nov 21) | 27869126 | 2016 |
Cellular uptake of lead in the blood-cerebrospinal fluid barrier: Novel roles of Connexin 43 hemicha ... | Song, Han; Zheng, Gang; Liu, Yang; Shen, Xue-Feng; Zhao, Zai-Hua; Aschner, Michael; Luo, Wen- ... | R01ES007331, R01ES010563 | Toxicol Appl Pharmacol (2016 Apr 15) | 26926986 | 2016 |
Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in ... | Reckziegel, Patrícia; Chen, Pan; Caito, Sam; Gubert, Priscila; Soares, Félix Alexandre Antunes; ... | R01ES010563 | Arch Toxicol (2016 Mar) | 25579234 | 2016 |
Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human In ... | Tidball, Andrew M; Neely, M Diana; Chamberlin, Reed; Aboud, Asad A; Kumar, Kevin K; Han, Bingy ... | R01ES010563 | PLoS One (2016) | 26982737 | 2016 |
Guarana (Paullinia cupana Mart.) attenuates methylmercury-induced toxicity in Caenorhabditis elegans ... | Arantes, Leticia Priscilla; Peres, Tanara Vieira; Chen, Pam; Caito, Samuel; Aschner, Michael; S ... | R01ES007331, R01ES010563 | Toxicol Res (Camb) (2016 Nov 01) | 28316775 | 2016 |
Involvement of heat shock proteins on Mn-induced toxicity in Caenorhabditis elegans. | Avila, Daiana Silva; Benedetto, Alexandre; Au, Catherine; Bornhorst, Julia; Aschner, Michael | R01ES007331, R01ES010563 | BMC Pharmacol Toxicol (2016 Nov 02) | 27802836 | 2016 |
Linear and Curvilinear Trajectories of Cortical Loss with Advancing Age and Disease Duration in Park ... | Claassen, Daniel O; Dobolyi, David G; Isaacs, David A; Roman, Olivia C; Herb, Joshua; Wylie, S ... | R01ES010563 | Aging Dis (2016 May) | 27330836 | 2016 |
Manganese and aging. | Parmalee, Nancy L; Aschner, Michael | R01ES010563 | Neurotoxicology (2016 Sep) | 27293182 | 2016 |
Methods for the Detection of Autophagy in Mammalian Cells. | Zhang, Ziyan; Singh, Rajat; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2016 08 01) | 27479363 | 2016 |
Null allele mutants of trt-1, the catalytic subunit of telomerase in Caenorhabditis elegans, are les ... | Ijomone, Omamuyovwi M; Miah, Mahfuzur R; Peres, Tanara V; Nwoha, Polycarp U; Aschner, Michael | R01ES010563 | Neurotoxicology (2016 Dec) | 27593554 | 2016 |
Preconditioning of endoplasmic reticulum stress protects against acrylonitrile-induced cytotoxicity ... | Yu, Bai; Wenjun, Zhao; Changsheng, Yin; Yuntao, Fang; Jing, Ma; Ben, Li; Hai, Qian; Guangwei, ... | R01ES007331, R01ES010563 | Neurotoxicology (2016 07) | 27260289 | 2016 |
Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes. | Yuntao, Fang; Chenjia, Guo; Panpan, Zhang; Wenjun, Zhao; Suhua, Wang; Guangwei, Xing; Haifeng, ... | R01ES007331, R01ES010563 | Arch Toxicol (2016 Feb) | 25488884 | 2016 |
Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through ... | Nguyen, Thuy T; Caito, Samuel W; Zackert, William E; West, James D; Zhu, Shijun; Aschner, Mich ... | R01ES007331, R01ES010563, T32ES007028 | Aging (Albany NY) (2016 08) | 27514077 | 2016 |
Sex- and structure-specific differences in antioxidant responses to methylmercury during early devel ... | Ruszkiewicz, Joanna A; Bowman, Aaron B; Farina, Marcelo; Rocha, João B T; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2016 Sep) | 27456245 | 2016 |
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuro ... | Tidball, Andrew M; Bryan, Miles R; Uhouse, Michael A; Kumar, Kevin K; Aboud, Asad A; Feist, Ja ... | R01ES010563 | Hum Mol Genet (2015 Apr 01) | 25489053 | 2015 |
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic mode ... | Chen, Pan; DeWitt, Margaret R; Bornhorst, Julia; Soares, Felix A; Mukhopadhyay, Somshuvra; Bowm ... | R01ES007331, R01ES010563 | Metallomics (2015 Feb) | 25531510 | 2015 |
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-de ... | Chun, Young Wook; Balikov, Daniel A; Feaster, Tromondae K; Williams, Charles H; Sheng, Calvin C ... | R01ES010563 | Biomaterials (2015 Oct) | 26204225 | 2015 |
Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity ... | Dimovasili, Christina; Aschner, Michael; Plaitakis, Andreas; Zaganas, Ioannis | R01ES010563 | Neurochem Int (2015 Sep) | 25837286 | 2015 |
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain ... | Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, ... | R01ES010563 | J Biomech (2015 Nov 05) | 26476764 | 2015 |
Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS. | Crone, Barbara; Aschner, Michael; Schwerdtle, Tanja; Karst, Uwe; Bornhorst, Julia | R01ES007331, R01ES010563 | Metallomics (2015 Jul) | 25996669 | 2015 |
Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurologica ... | Karki, Pratap; Smith, Keisha; Johnson Jr, James; Aschner, Michael; Lee, Eunsook Y | R01ES010563 | Neurochem Res (2015 Feb) | 25064045 | 2015 |
High-resolution multi-photon imaging of morphological structures of caenorhabditis elegans. | Bixel, M Gabriele; Fretham, Stephanie J B; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2015 May) | 26309451 | 2015 |
High-Resolution Multi-Photon Imaging of Morphological Structures of Caenorhabditis elegans. | Bixel, Gabriele M; Fretham, Stephanie J B; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2015 05 04) | 26344221 | 2015 |
Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrom ... | Schumacher, Fabian; Chakraborty, Sudipta; Kleuser, Burkhard; Gulbins, Erich; Schwerdtle, Tanja; ... | R01ES007331, R01ES010563 | Talanta (2015 Nov 01) | 26452793 | 2015 |
Lead, Arsenic, and Manganese Metal Mixture Exposures: Focus on Biomarkers of Effect. | Andrade, V M; Mateus, M L; Batoréu, M C; Aschner, M; Marreilha dos Santos, A P | R01ES010563 | Biol Trace Elem Res (2015 Jul) | 25693681 | 2015 |
Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans. | Chakraborty, Sudipta; Chen, Pan; Bornhorst, Julia; Schwerdtle, Tanja; Schumacher, Fabian; Kleus ... | R01ES007331, R01ES010563 | Metallomics (2015 May) | 25769119 | 2015 |
Manganese homeostasis in the nervous system. | Chen, Pan; Chakraborty, Sudipta; Mukhopadhyay, Somshuvra; Lee, Eunsook; Paoliello, Monica M B; ... | R01ES010563 | J Neurochem (2015 Aug) | 25982296 | 2015 |
Manganese Is Essential for Neuronal Health. | Horning, Kyle J; Caito, Samuel W; Tipps, K Grace; Bowman, Aaron B; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Annu Rev Nutr (2015) | 25974698 | 2015 |
Manganese-induced Neurotoxicity: From C. elegans to Humans. | Chen, Pan; Chakraborty, Sudipta; Peres, Tanara V; Bowman, Aaron B; Aschner, Michael | R01ES007331, R01ES010563 | Toxicol Res (Camb) (2015 Mar 01) | 25893090 | 2015 |
Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features. | Kwakye, Gunnar F; Paoliello, Monica M B; Mukhopadhyay, Somshuvra; Bowman, Aaron B; Aschner, Mic ... | R01ES010563 | Int J Environ Res Public Health (2015 Jul 06) | 26154659 | 2015 |
Mir-203-mediated tricellulin mediates lead-induced in vitro loss of blood-cerebrospinal fluid barrie ... | Su, Peng; Zhao, Fang; Cao, Zipeng; Zhang, Jianbin; Aschner, Michael; Luo, Wenjing | R01ES007331, R01ES010563 | Toxicol In Vitro (2015 Aug) | 25975750 | 2015 |
Mitochondrial Redox Dysfunction and Environmental Exposures. | Caito, Samuel W; Aschner, Michael | R01ES007331, R01ES010563 | Antioxid Redox Signal (2015 Aug 20) | 25826672 | 2015 |
Neuroimaging identifies increased manganese deposition in infants receiving parenteral nutrition. | Aschner, Judy L; Anderson, Adam; Slaughter, James Christopher; Aschner, Michael; Steele, Steven ... | R01ES010563 | Am J Clin Nutr (2015 Dec) | 26561627 | 2015 |
New tools for the quantitative assessment of prodrug delivery and neurotoxicity. | Samuelson, Lynn E; Scherer, Randy L; VanSaun, Michael N; Fan, Kang-Hsien; Dozier, E Ashley; Car ... | R01ES007331, R01ES010563 | Neurotoxicology (2015 Mar) | 25732874 | 2015 |
PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper. | Aboud, Asad A; Tidball, Andrew M; Kumar, Kevin K; Neely, M Diana; Han, Bingying; Ess, Kevin C; ... | R01ES010563 | Neurobiol Dis (2015 Jan) | 25315681 | 2015 |
Protective effects of novel organic selenium compounds against oxidative stress in the nematode Caen ... | Stefanello, Sílvio Terra; Gubert, Priscila; Puntel, Bruna; Mizdal, Caren Rigon; de Campos, Marl ... | R01ES007331, R01ES010563 | Toxicol Rep (2015) | 26726309 | 2015 |
Quantification of Glutathione in Caenorhabditis elegans. | Caito, Samuel W; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2015) | 26309452 | 2015 |
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic ... | Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; S ... | R01ES010563 | Biomicrofluidics (2015 Sep) | 26576206 | 2015 |
RNASeq in C. elegans Following Manganese Exposure. | Parmalee, Nancy L; Maqbool, Shahina B; Ye, Bin; Calder, Brent; Bowman, Aaron B; Aschner, Micha ... | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2015 Aug 06) | 26250396 | 2015 |
Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate trans ... | Karki, Pratap; Smith, Keisha; Johnson Jr, James; Aschner, Michael; Lee, Eunsook | R01ES010563 | Neurochem Int (2015 Sep) | 25128239 | 2015 |
SLC30A10: A novel manganese transporter. | Chen, Pan; Bowman, Aaron B; Mukhopadhyay, Somshuvra; Aschner, Michael | R01ES010563 | Worm (2015 Jul-Sep) | 26430566 | 2015 |
Structural and functional changes in the zebrafish (Danio rerio) skeletal muscle after cadmium expos ... | Avallone, Bice; Agnisola, Claudio; Cerciello, Raimondo; Panzuto, Raffaele; Simoniello, Palma; C ... | R01ES010563 | Cell Biol Toxicol (2015 Dec) | 26715392 | 2015 |
Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB a ... | Karki, Pratap; Kim, Clifford; Smith, Keisha; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook | R01ES007331, R01ES010563 | J Biol Chem (2015 Sep 25) | 26269591 | 2015 |
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal man ... | Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschne ... | R01ES010563 | Metallomics (2015 Feb) | 25599126 | 2015 |
Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures. | Exil, Vernat; Ping, Li; Yu, Yingchun; Chakraborty, Sudipta; Caito, Samuel W; Wells, K Sam; Kar ... | R01ES010563 | PLoS One (2014) | 24787138 | 2014 |
Anthocyanin-rich açaí (Euterpe oleracea Mart.) extract attenuates manganese-induced oxidative stress ... | da Silva Santos, Vivian; Bisen-Hersh, Emily; Yu, Yingchun; Cabral, Ingridy Simone Ribeiro; Nardi ... | R01ES010563 | J Toxicol Environ Health A (2014) | 24617543 | 2014 |
Arsenic and manganese alter lead deposition in the rat. | Andrade, V; Mateus, M L; Santos, D; Aschner, M; Batoreu, M C; Marreilha dos Santos, A P | R01ES010563 | Biol Trace Elem Res (2014 Jun) | 24715659 | 2014 |
Cellular manganese content is developmentally regulated in human dopaminergic neurons. | Kumar, Kevin K; Lowe Jr, Edward W; Aboud, Asad A; Neely, M Diana; Redha, Rey; Bauer, Joshua A; ... | R01ES010563 | Sci Rep (2014 Oct 28) | 25348053 | 2014 |
Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by ... | Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; Marreilha dos Santos, A P | R01ES010563 | Neurotoxicology (2014 Dec) | 25451970 | 2014 |
Considerations on manganese (Mn) treatments for in vitro studies. | Bowman, Aaron B; Aschner, Michael | R01ES010563 | Neurotoxicology (2014 Mar) | 24509086 | 2014 |
Elemental bioimaging of manganese uptake in C. elegans. | Brinkhaus, Sigrid Grosse; Bornhorst, Julia; Chakraborty, Sudipta; Wehe, Christoph A; Niehaus, R ... | R01ES007331, R01ES010563 | Metallomics (2014 Mar) | 24481269 | 2014 |
F3-Isoprostanes as a Measure of in vivo Oxidative Damage in Caenorhabditis elegans. | Nguyen, Thuy T; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2014 Nov 06) | 25378241 | 2014 |
Manganese in human parenteral nutrition: considerations for toxicity and biomonitoring. | Santos, Dinamene; Batoreu, Camila; Mateus, Luisa; Marreilha Dos Santos, A P; Aschner, Michael | R01ES010563 | Neurotoxicology (2014 Jul) | 24184781 | 2014 |
Recent Advances in Mercury Research. | Martinez-Finley, Ebany J; Aschner, Michael | R01ES007331, R01ES010563 | Curr Environ Health Rep (2014 Jun) | 28018837 | 2014 |
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutation ... | Leyva-Illades, Dinorah; Chen, Pan; Zogzas, Charles E; Hutchens, Steven; Mercado, Jonathan M; Sw ... | R01ES007331, R01ES010563 | J Neurosci (2014 Oct 15) | 25319704 | 2014 |
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein ... | Bornhorst, Julia; Chakraborty, Sudipta; Meyer, Sören; Lohren, Hanna; Brinkhaus, Sigrid Grosse; ... | R01ES010563, T32ES007028 | Metallomics (2014 Mar) | 24452053 | 2014 |
The interaction between microglia and neural stem/precursor cells. | Su, Peng; Zhang, Jianbin; Zhao, Fang; Aschner, Michael; Chen, Jingyuan; Luo, Wenjing | R01ES007331, R01ES010563 | Brain Res Bull (2014 Oct) | 25245208 | 2014 |
Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease ... | Karki, Pratap; Webb, Anton; Smith, Keisha; Johnson Jr, James; Lee, Kyuwon; Son, Deok-Soo; Asch ... | R01ES010563 | Mol Cell Biol (2014 Apr) | 24469401 | 2014 |
Acrylonitrile has Distinct Hormetic Effects on Acetyl-Cholinesterase Activity in Mouse Brain and Blo ... | Yuanqing, He; Suhua, Wang; Guangwei, Xing; Chunlan, Ren; Hai, Qian; Wenrong, Xu; Rongzhu, Lu; ... | R01ES007331, R01ES010563 | Dose Response (2013) | 23550232 | 2013 |
cAMP response element-binding protein (CREB) and nuclear factor κB mediate the tamoxifen-induced up- ... | Karki, Pratap; Webb, Anton; Smith, Keisha; Lee, Kyuwon; Son, Deok-Soo; Aschner, Michael; Lee, ... | R01ES010563 | J Biol Chem (2013 Oct 04) | 23955341 | 2013 |
Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stres ... | López-Granero, Caridad; Cañadas, Fernando; Cardona, Diana; Yu, Yingchun; Giménez, Estela; Lozan ... | R01ES007331, R01ES010563 | Toxicol Sci (2013 Jan) | 22986948 | 2013 |
Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential ... | Zimmermann, Luciana T; Santos, Danúbia B; Naime, Aline A; Leal, Rodrigo B; Dórea, José G; Barbo ... | R01ES007331, R01ES010563 | Neurotoxicology (2013 Sep) | 23727015 | 2013 |
Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential p ... | Santos, Dinamene; Batoreu, M Camila; Aschner, Michael; Marreilha dos Santos, Ana P | R01ES010563 | Biol Trace Elem Res (2013 Apr) | 23315311 | 2013 |
Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia. | Caito, Samuel; Yu, Yingchun; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Neurotoxicology (2013 Jul) | 23628792 | 2013 |
Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-d ... | Caito, Samuel W; Valentine, William M; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | J Neurochem (2013 Dec) | 23786526 | 2013 |
Estrogen attenuates manganese-induced glutamate transporter impairment in rat primary astrocytes. | Lee, Eunsook; Sidoryk-Wegrzynowicz, Marta; Farina, Marcelo; Rocha, Joao B T; Aschner, Michael | R01ES010563 | Neurotox Res (2013 Feb) | 22878846 | 2013 |
Evaluation of neurobehavioral and neuroinflammatory end-points in the post-exposure period in rats s ... | Santos, Dinamene; Dinamene, Santos; Batoréu, M Camila; Camila, Batoreu M; Tavares de Almeida, I ... | R01ES010563 | Toxicology (2013 Dec 06) | 24060432 | 2013 |
Hormetic effects of acute methylmercury exposure on grp78 expression in rat brain cortex. | Zhang, Ye; Lu, Rongzhu; Liu, Wenshuai; Wu, Ying; Qian, Hai; Zhao, Xiaowu; Wang, Suhua; Xing, ... | R01ES007331, R01ES010563 | Dose Response (2013) | 23549286 | 2013 |
In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from ... | Peres, Tanara Vieira; Pedro, Daniela Zótico; de Cordova, Fabiano Mendes; Lopes, Mark William; Go ... | R01ES010563 | Biomed Res Int (2013) | 24324973 | 2013 |
Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations. | DeWitt, Margaret R; Chen, Pan; Aschner, Michael | R01ES010563, T32ES007028 | Biochem Biophys Res Commun (2013 Mar 01) | 23357421 | 2013 |
Manganese homeostasis and transport. | Roth, Jerome; Ponzoni, Silvia; Aschner, Michael | R01ES007331, R01ES010563 | Met Ions Life Sci (2013) | 23595673 | 2013 |
Manganese in health and disease. | Avila, Daiana Silva; Puntel, Robson Luiz; Aschner, Michael | R01ES007331, R01ES010563 | Met Ions Life Sci (2013) | 24470093 | 2013 |
Manganese neurotoxicity and the role of reactive oxygen species. | Martinez-Finley, Ebany J; Gavin, Claire E; Aschner, Michael; Gunter, Thomas E | R01ES010563, T32ES007028 | Free Radic Biol Med (2013 Sep) | 23395780 | 2013 |
Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired ... | Maitre, Nathalie L; Aschner, Judy L; Aschner, Michael | R01ES010563 | J Nutr (2013 Apr) | 23515251 | 2013 |
Manganese neurotoxicity: a focus on glutamate transporters. | Karki, Pratap; Lee, Eunsook; Aschner, Michael | R01ES010563 | Ann Occup Environ Med (2013 May 21) | 24472696 | 2013 |
Manganese toxicity in the central nervous system: the glutamine/glutamate-ýý-aminobutyric acid cycle ... | Sidoryk-Wegrzynowicz, M; Aschner, M | R01ES010563 | J Intern Med (2013 May) | 23360507 | 2013 |
Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reve ... | Cordova, Fabiano M; Aguiar Jr, Aderbal S; Peres, Tanara V; Lopes, Mark W; Gonçalves, Filipe M; ... | R01ES007331, R01ES010563 | Arch Toxicol (2013 Jul) | 23385959 | 2013 |
Metal-induced neurodegeneration in C. elegans. | Chen, Pan; Martinez-Finley, Ebany J; Bornhorst, Julia; Chakraborty, Sudipta; Aschner, Michael | R01ES010563, T32ES007028 | Front Aging Neurosci (2013) | 23730287 | 2013 |
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury. | Farina, Marcelo; Avila, Daiana Silva; da Rocha, Joao Batista Teixeira; Aschner, Michael | R01ES007331, R01ES010563 | Neurochem Int (2013 Apr) | 23266600 | 2013 |
Optimization of fluorescence assay of cellular manganese status for high throughput screening. | Kumar, Kevin K; Aboud, Asad A; Patel, Devin K; Aschner, Michael; Bowman, Aaron B | R01ES010563 | J Biochem Mol Toxicol (2013 Jan) | 23169769 | 2013 |
Organochalcogens inhibit mitochondrial complexes I and II in rat brain: possible implications for ne ... | Puntel, Robson Luiz; Roos, Daniel Henrique; Seeger, Rodrigo Lopes; Aschner, Michael; Rocha, Joã ... | R01ES007331, R01ES010563 | Neurotox Res (2013 Aug) | 23224748 | 2013 |
Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegan ... | Chakraborty, Sudipta; Bornhorst, Julia; Nguyen, Thuy T; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Int J Mol Sci (2013 Nov 21) | 24284401 | 2013 |
Role of astrocytes in manganese mediated neurotoxicity. | Sidoryk-Wegrzynowicz, Marta; Aschner, Michael | R01ES010563 | BMC Pharmacol Toxicol (2013) | 23594835 | 2013 |
SyM-BBB: a microfluidic Blood Brain Barrier model. | Prabhakarpandian, Balabhaskar; Shen, Ming-Che; Nichols, Joseph B; Mills, Ivy R; Sidoryk-Wegrzyno ... | R01ES007331, R01ES010563 | Lab Chip (2013 Mar 21) | 23344641 | 2013 |
Urinary delta-ALA: a potential biomarker of exposure and neurotoxic effect in rats co-treated with a ... | Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; dos Santos, A P Marreilha | R01ES010563 | Neurotoxicology (2013 Sep) | 23764341 | 2013 |
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K ... | Lee, Eunsook; Yin, Zhaobao; Sidoryk-Węgrzynowicz, Marta; Jiang, Haiyan; Aschner, Michael | R01ES010563 | Free Radic Biol Med (2012 Mar 15) | 22245093 | 2012 |
Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassi ... | Skowrońska, Marta; Zielińska, Magdalena; Wójcik-Stanaszek, Luiza; Ruszkiewicz, Joanna; Milatovic ... | R01ES007331, R01ES010563 | J Neurochem (2012 Apr) | 22260250 | 2012 |
Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model. | Avila, Daiana Silva; Somlyai, Gábor; Somlyai, Ildikó; Aschner, Michael | R01ES007331, R01ES010563 | Toxicol Lett (2012 Jun 20) | 22561170 | 2012 |
C. elegans and Neurodegeneration In Caenorhabditis Elegans: Anatomy, Life Cycles and Biological Func ... | Martinez-Finley, Ebany J; Chakraborty, Sudipta; Caito, Sam; Fretham, Stephanie; Aschner, Michae ... | R01ES007331, R01ES010563 | Adv Med Biol (2012) | 32346495 | 2012 |
Cellular transport and homeostasis of essential and nonessential metals. | Martinez-Finley, Ebany J; Chakraborty, Sudipta; Fretham, Stephanie J B; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Metallomics (2012 Jul) | 22337135 | 2012 |
Current needs and future directions of occupational safety and heath in a globalized world. | Perera, Frederica P; Li, T Y; Lin, C; Tang, Deliang; Gilbert, Steven G; Kang, Seong-Kyu; Aschn ... | R01ES007331, R01ES010563 | Neurotoxicology (2012 Aug) | 22037493 | 2012 |
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striata ... | Madison, Jennifer L; Wegrzynowicz, Michal; Aschner, Michael; Bowman, Aaron B | R01ES010563 | PLoS One (2012) | 22363539 | 2012 |
Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans. | Caito, Samuel; Fretham, Stephanie; Martinez-Finley, Ebany; Chakraborty, Sudipta; Avila, Daiana; ... | R01ES007331, R01ES010563, T32ES007028 | Front Genet (2012) | 22514555 | 2012 |
GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. | Lee, Eunsook; Sidoryk-Wêgrzynowicz, Marta; Wang, Ning; Webb, Anton; Son, Deok-Soo; Lee, Kyuwon ... | R01ES010563 | J Biol Chem (2012 Aug 03) | 22645130 | 2012 |
In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and i ... | Cordova, Fabiano M; Aguiar Jr, Aderbal S; Peres, Tanara V; Lopes, Mark W; Gonçalves, Filipe M; ... | R01ES010563 | PLoS One (2012) | 22427945 | 2012 |
Manganese alters rat brain amino acids levels. | Santos, Dinamene; Batoreu, M Camila; Almeida, Isabel; Ramos, Ruben; Sidoryk-Wegrzynowicz, M; As ... | R01ES010563 | Biol Trace Elem Res (2012 Dec) | 22971893 | 2012 |
Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover ... | Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Aschner, Michael | R01ES010563 | J Neurochem (2012 Aug) | 22708868 | 2012 |
Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity. | Fretham, Stephanie Jb; Caito, Samuel; Martinez-Finley, Ebany J; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Toxicol Res (Camb) (2012 Jul 01) | 27795823 | 2012 |
New strategies in neuroprotection and neurorepair. | Antonelli, Marta C; Guillemin, Gilles J; Raisman-Vozari, Rita; Del-Bel, Elaine A; Aschner, Mich ... | R01ES007331, R01ES010563 | Neurotox Res (2012 Jan) | 21861211 | 2012 |
Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans ... | Avila, Daiana Silva; Benedetto, Alexandre; Au, Catherine; Manarin, Flávia; Erikson, Keith; Soar ... | R01ES007331, R01ES010563 | Free Radic Biol Med (2012 May 01) | 22406322 | 2012 |
Pathophysiology of manganese-associated neurotoxicity. | Racette, Brad A; Aschner, Michael; Guilarte, Tomas R; Dydak, Ulrike; Criswell, Susan R; Zheng, ... | R01ES010563 | Neurotoxicology (2012 Aug) | 22202748 | 2012 |
Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circul ... | Fike, Candice D; Sidoryk-Wegrzynowicz, Marta; Aschner, Michael; Summar, Marshall; Prince, Lawre ... | R01ES007331, R01ES010563 | Cardiovasc Res (2012 Aug 01) | 22673370 | 2012 |
Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induce ... | Santos, A P Marreilha Dos; Lucas, Rui L; Andrade, Vanda; Mateus, M Luisa; Milatovic, Dejan; Asc ... | R01ES010563 | Toxicol Appl Pharmacol (2012 Feb 1) | 22178737 | 2012 |
The Caenorhabiditis elegans model as a reliable tool in neurotoxicology. | Avila, Daiana; Helmcke, Kirsten; Aschner, Michael | R01ES007331, R01ES010563 | Hum Exp Toxicol (2012 Mar) | 21148196 | 2012 |
The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and ne ... | Santos, Dinamene; Milatovic, Dejan; Andrade, Vanda; Batoreu, M Camila; Aschner, Michael; Marrei ... | R01ES010563 | Toxicology (2012 Feb 26) | 22154916 | 2012 |
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 i ... | Lee, Eunsook; Sidoryk-Wegrzynowicz, Marta; Yin, Zhaobao; Webb, Anton; Son, Deok-Soo; Aschner, ... | R01ES010563 | Glia (2012 Jul) | 22488924 | 2012 |
Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway ... | Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Mingwei, Ni; Aschner, Michael | R01ES010563 | Glia (2011 Nov) | 21812036 | 2011 |
Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms. | Aitlhadj, Layla; Avila, Daiana Silva; Benedetto, Alexandre; Aschner, Michael; Stürzenbaum, Step ... | R01ES010563 | Environ Health Perspect (2011 Jan) | 20797931 | 2011 |
Gender and manganese exposure interactions on mouse striatal neuron morphology. | Madison, Jennifer L; Wegrzynowicz, Michal; Aschner, Michael; Bowman, Aaron B | R01ES010563 | Neurotoxicology (2011 Dec) | 21641932 | 2011 |
Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases. | Martinez-Finley, Ebany J; Avila, Daiana Silva; Chakraborty, Sudipta; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Metallomics (2011 Mar) | 21210060 | 2011 |
Introducing cloned genes into cultured neurons providing novel in vitro models for neuropathology an ... | Farina, Marcelo; Berenguer, Jordi; Pons, Sebastián; da Rocha, João Batista Teixeira; Aschner, M ... | R01ES007331, R01ES010563 | Neuromethods (2011) | 32132768 | 2011 |
Measurement of isoprostanes as markers of oxidative stress. | Milatovic, Dejan; Montine, Thomas J; Aschner, Michael | R01ES007331, R01ES010563 | Methods Mol Biol (2011) | 21815067 | 2011 |
Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase. | Milatovic, Dejan; Jenkins, Jerry W; Hood, Jonathan E; Yu, Yingchun; Rongzhu, Lu; Aschner, Mich ... | R01ES007331, R01ES010563, T32ES007028 | Neurotoxicology (2011 Oct) | 21241737 | 2011 |
Prolactin is a peripheral marker of manganese neurotoxicity. | Marreilha Dos Santos, A P; Lopes Santos, M; Batoréu, Maria C; Aschner, M | R01ES010563 | Brain Res (2011 Mar 25) | 21262206 | 2011 |
Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity. | Milatovic, Dejan; Montine, Thomas J; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2011 Jun) | 21376752 | 2011 |
Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative ... | Milatovic, Dejan; Gupta, Ramesh C; Yu, Yingchun; Zaja-Milatovic, Snjezana; Aschner, Michael | R01ES010563 | Toxicol Appl Pharmacol (2011 Nov 01) | 21684300 | 2011 |
Role of astrocytes in brain function and disease. | Sidoryk-Wegrzynowicz, Marta; Wegrzynowicz, Michal; Lee, Eunsook; Bowman, Aaron B; Aschner, Mich ... | R01ES010563 | Toxicol Pathol (2011 Jan) | 21075920 | 2011 |
Role of manganese in neurodegenerative diseases. | Bowman, Aaron B; Kwakye, Gunnar F; Herrero Hernández, Elena; Aschner, Michael | R01ES010563 | J Trace Elem Med Biol (2011 Dec) | 21963226 | 2011 |
Volume measurements in cultured primary astrocytes. | Aschner, Michael | R01ES007331, R01ES010563 | Methods Mol Biol (2011) | 21815080 | 2011 |
γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases bra ... | Le, Truc M; Jiang, Haiyan; Cunningham, Gary R; Magarik, Jordan A; Barge, William S; Cato, Mari ... | R01ES007331, R01ES010563 | Neurotoxicology (2011 Oct) | 21159318 | 2011 |
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model a ... | Williams, B Blairanne; Kwakye, Gunnar F; Wegrzynowicz, Michal; Li, Daphne; Aschner, Michael; Er ... | R01ES010563 | Toxicol Sci (2010 Sep) | 20547568 | 2010 |
Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic reso ... | Williams, Jason M; Milatovic, Dejan; Gore, John C; Aschner, Michael; Avison, Malcolm J | R01ES010563 | Toxicol Sci (2010 Apr) | 20061340 | 2010 |
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manga ... | Williams, B Blairanne; Li, Daphne; Wegrzynowicz, Michal; Vadodaria, Bhavin K; Anderson, Joel G; ... | R01ES010563 | J Neurochem (2010 Jan) | 19845833 | 2010 |
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic ... | Benedetto, Alexandre; Au, Catherine; Avila, Daiana Silva; Milatovic, Dejan; Aschner, Michael | R01ES010563 | PLoS Genet (2010 Aug 26) | 20865164 | 2010 |
Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation ... | Yin, Zhaobao; Jiang, Haiyan; Lee, Eun-Sook Y; Ni, Mingwei; Erikson, Keith M; Milatovic, Dejan; ... | R01ES010563 | J Neurochem (2010 Mar) | 20002294 | 2010 |
Gene-environment interactions: neurodegeneration in non-mammals and mammals. | Aschner, Michael; Levin, Edward D; Suñol, Cristina; Olopade, James O; Helmcke, Kirsten J; Avila ... | P42ES010356, R01ES007331, R01ES010563 | Neurotoxicology (2010 Sep) | 20359493 | 2010 |
Hormetic effect of methylmercury on Caenorhabditis elegans. | Helmcke, Kirsten J; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Toxicol Appl Pharmacol (2010 Oct 15) | 20691719 | 2010 |
Introduction to the special issue on emerging high throughput and complementary model screens for ne ... | Aschner, M; Crofton, K M; Levin, E D | P42ES010356, R01ES010563 | Neurotoxicol Teratol (2010 Jan-Feb) | 19703556 | 2010 |
Manganese (Mn) and iron (Fe): interdependency of transport and regulation. | Fitsanakis, Vanessa A; Zhang, Na; Garcia, Stephanie; Aschner, Michael | R01ES010563 | Neurotox Res (2010 Aug) | 19921534 | 2010 |
Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediat ... | Sidoryk-Wegrzynowicz, Marta; Lee, Eun-Sook; Ni, Mingwei; Aschner, Michael | R01ES007331, R01ES010563 | Glia (2010 Dec) | 20737472 | 2010 |
Morphometric analysis in neurodegenerative disorders. | Milatovic, Dejan; Montine, Thomas J; Zaja-Milatovic, Snjezana; Madison, Jennifer L; Bowman, Aar ... | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2010 Nov) | 21049492 | 2010 |
Morphometric analysis in neurodegenerative disorders. | Milatovic, Dejan; Montine, Thomas J; Zaja-Milatovic, Snjezana; Madison, Jennifer L; Bowman, Aar ... | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2010 Feb) | 20401325 | 2010 |
Neonatal rat primary microglia: isolation, culturing, and selected applications. | Ni, Mingwei; Aschner, Michael | R01ES007331, R01ES010563 | Curr Protoc Toxicol (2010 Feb) | 20960423 | 2010 |
Rat brain endothelial cells are a target of manganese toxicity. | dos Santos, Ana Paula Marreilha; Milatovic, Dejan; Au, Catherine; Yin, Zhaobao; Batoreu, Maria ... | R01ES010563 | Brain Res (2010 Apr 22) | 20170646 | 2010 |
Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and ... | Exil, Vernat J; Silva Avila, Daiana; Benedetto, Alexandre; Exil, Elizabeth A; Adams, Margaret R ... | R01ES010563 | PLoS One (2010 Dec 03) | 21151927 | 2010 |
A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress ... | Fitsanakis, Vanessa A; Thompson, Kimberly N; Deery, Sarah E; Milatovic, Dejan; Shihabi, Zak K; ... | R01ES010563 | Neurotox Res (2009 Feb) | 19384579 | 2009 |
A model for the analysis of competitive relaxation effects of manganese and iron in vivo. | Zhang, Na; Fitsanakis, Vanessa A; Erikson, Keith M; Aschner, Michael; Avison, Malcolm J; Gore, ... | R01ES007331, R01ES010563 | NMR Biomed (2009 May) | 19137511 | 2009 |
Changes in Dietary Iron Levels Affect Brain Manganese Accumulation and Distribution. | Fitsanakis, Vanessa A; Finkelstein, Yoram; Aschner, Michael | R01ES010563 | Cell Biol Toxicol (2009) | 32390688 | 2009 |
Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes. | Lee, Eun-Sook Y; Sidoryk, Marta; Jiang, Haiyan; Yin, Zhaobao; Aschner, Michael | R01ES010563 | J Neurochem (2009 Jul) | 19453300 | 2009 |
Genetic aspects of behavioral neurotoxicology. | Levin, Edward D; Aschner, Michael; Heberlein, Ulrike; Ruden, Douglas; Welsh-Bohmer, Kathleen A; ... | P42ES010356, R01ES010563 | Neurotoxicology (2009 Sep) | 19647018 | 2009 |
Manganese disrupts astrocyte glutamine transporter expression and function. | Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Albrecht, Jan; Aschner, Michael | R01ES010563 | J Neurochem (2009 Aug) | 19457077 | 2009 |
Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal gangl ... | Stanwood, Gregg D; Leitch, Duncan B; Savchenko, Valentina; Wu, Jane; Fitsanakis, Vanessa A; And ... | R01ES010563 | J Neurochem (2009 Jul) | 19457100 | 2009 |
Methamphetamine Dysregulates Redox Status in Primary Rat Astrocyte and Mesencephalic Neuronal Cultur ... | Ali, S F; Jiang, H; Rongzhu, L; Milatovic, D; Aschner, M | R01ES007331, R01ES010563 | Am J Neuroprot Neuroregen (2009 Jun) | 30627316 | 2009 |
Oxidative damage and neurodegeneration in manganese-induced neurotoxicity. | Milatovic, Dejan; Zaja-Milatovic, Snjezana; Gupta, Ramesh C; Yu, Yingchun; Aschner, Michael | R01ES010563 | Toxicol Appl Pharmacol (2009 Oct 15) | 19607852 | 2009 |
SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese level ... | Au, Catherine; Benedetto, Alexandre; Anderson, Joel; Labrousse, Arnaud; Erikson, Keith; Ewbank, ... | R01ES010563 | PLoS One (2009 Nov 18) | 19924247 | 2009 |
The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabdi ... | Settivari, Raja; Levora, Jennifer; Nass, Richard | R01ES010563 | J Biol Chem (2009 Dec 18) | 19801673 | 2009 |
Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans. | McCaughan, Danny; Au, Catherine; Benedetto, Alexandre; Milatovic, Dejan; Aschner, Judy; Aschner ... | R01ES007331, R01ES010563 | Int J Neuroprot Neuroregener (2008) | 31178919 | 2008 |
Differential deposition of manganese in the rat brain following subchronic exposure to manganese: a ... | Finkelstein, Yoram; Zhang, Na; Fitsanakis, Vanessa A; Avison, Malcolm J; Gore, John C; Aschner, ... | R01ES010563 | Isr Med Assoc J (2008 Nov) | 19070289 | 2008 |
Leaching of trace elements from biological tissue by formalin fixation. | Gellein, Kristin; Flaten, Trond Peder; Erikson, Keith M; Aschner, Michael; Syversen, Tore | R01ES010563 | Biol Trace Elem Res (2008 Mar) | 17952381 | 2008 |
Manganese transport in eukaryotes: the role of DMT1. | Au, Catherine; Benedetto, Alexandre; Aschner, Michael | R01ES010563 | Neurotoxicology (2008 Jul) | 18565586 | 2008 |
Manganese Transport into the Brain: Putative Mechanisms. | Aschner, Michael; Dos Santos, Ana Paula Marreilha; Erikson, Keith M; Zheng, Wei | R01ES007331, R01ES010563 | Met Ions Biol Med (2008 May) | 30595649 | 2008 |
Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese tre ... | Fitsanakis, Vanessa A; Zhang, Na; Anderson, Joel G; Erikson, Keith M; Avison, Malcolm J; Gore, ... | R01ES007331, R01ES010563 | Toxicol Sci (2008 May) | 18234737 | 2008 |
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. | West, Adrian K; Hidalgo, Juan; Eddins, Donnie; Levin, Edward D; Aschner, Michael | P42ES010356, R01ES007331, R01ES010563 | Neurotoxicology (2008 May) | 18313142 | 2008 |
Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures. | Yin, Zhaoobao; Aschner, Judy L; dos Santos, Ana Paula; Aschner, Michael | R01ES010563 | Brain Res (2008 Apr 8) | 18313649 | 2008 |
Effects of manganese on thyroid hormone homeostasis: potential links. | Soldin, O P; Aschner, M | R01ES010563 | Neurotoxicology (2007 Sep) | 17576015 | 2007 |
Manganese induces oxidative impairment in cultured rat astrocytes. | Milatovic, Dejan; Yin, Zhaobao; Gupta, Ramesh C; Sidoryk, Marta; Albrecht, Jan; Aschner, Judy ... | R01ES010563 | Toxicol Sci (2007 Jul) | 17468184 | 2007 |
Manganese neurotoxicity: a focus on the neonate. | Erikson, Keith M; Thompson, Khristy; Aschner, Judy; Aschner, Michael | R01ES010563 | Pharmacol Ther (2007 Feb) | 17084903 | 2007 |
Manganese: recent advances in understanding its transport and neurotoxicity. | Aschner, Michael; Guilarte, Tomás R; Schneider, Jay S; Zheng, Wei | R01ES010563 | Toxicol Appl Pharmacol (2007 Jun 01) | 17466353 | 2007 |
Modulation of cholinergic systems by manganese. | Finkelstein, Yoram; Milatovic, Dejan; Aschner, Michael | R01ES010563 | Neurotoxicology (2007 Sep) | 17920128 | 2007 |
Putative proteins involved in manganese transport across the blood-brain barrier. | Fitsanakis, Vanessa A; Piccola, Greg; Marreilha dos Santos, Ana Paula; Aschner, Judy L; Aschner, ... | R01ES010563 | Hum Exp Toxicol (2007 Apr) | 17615110 | 2007 |
Role of glutathione in determining the differential sensitivity between the cortical and cerebellar ... | Kaur, Parvinder; Aschner, Michael; Syversen, Tore | R01ES010563 | Toxicology (2007 Feb 12) | 17169475 | 2007 |
Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model ... | Fitsanakis, Vanessa A; Piccola, Greg; Aschner, Judy L; Aschner, Michael | R01ES010563 | Neurotoxicology (2006 Jan) | 16169084 | 2006 |
Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primar ... | Erikson, Keith M; Aschner, Michael | R01ES010563 | Neurotoxicology (2006 Jan) | 16140386 | 2006 |
Manganese transport by rat brain endothelial (RBE4) cell-based transwell model in the presence of as ... | Fitsanakis, Vanessa A; Piccola, Greg; Aschner, Judy L; Aschner, Michael | R01ES010563 | J Neurosci Res (2005 Jul 15) | 15948148 | 2005 |
Nutritional aspects of manganese homeostasis. | Aschner, Judy L; Aschner, Michael | R01ES010563 | Mol Aspects Med (2005) | 16099026 | 2005 |
The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by ... | Mutkus, Lysette; Aschner, Judy L; Fitsanakis, Vanessa; Aschner, Michael | R01ES010563 | Biol Trace Elem Res (2005 Dec) | 16286678 | 2005 |
The role of MT in neurological disorders. | Aschner, Michael; West, Adrian K | R01ES007331, R01ES010563 | J Alzheimers Dis (2005 Nov) | 16308482 | 2005 |
Developmental neuropathology of environmental agents. | Costa, Lucio G; Aschner, Michael; Vitalone, Annabella; Syversen, Tore; Soldin, Offie Porat | P30ES007033, R01ES007331, R01ES010563 | Annu Rev Pharmacol Toxicol (2004) | 14744240 | 2004 |
Manganese exposure and induced oxidative stress in the rat brain. | Erikson, Keith M; Dobson, Allison W; Dorman, David C; Aschner, Michael | R01ES007331, R01ES010563 | Sci Total Environ (2004 Dec 01) | 15504526 | 2004 |
Manganese-induced cytotoxicity in dopamine-producing cells. | Stredrick, Denise L; Stokes, Alan H; Worst, Travis J; Freeman, Willard M; Johnson, Elizabeth A; ... | R01ES010563 | Neurotoxicology (2004 Jun) | 15183009 | 2004 |
Neurotoxicology: principles and considerations of in vitro assessment. | Aschner, Michael; Syversen, Tore | R01ES007331, R01ES010563 | Altern Lab Anim (2004 Oct) | 15651915 | 2004 |
Brain barrier systems: a new frontier in metal neurotoxicological research. | Zheng, Wei; Aschner, Michael; Ghersi-Egea, Jean-Francois | P30ES009089, R01ES007331, R01ES010563 | Toxicol Appl Pharmacol (2003 Oct 01) | 14554098 | 2003 |
Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitr ... | Yang, Jian; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2003 Aug) | 12900088 | 2003 |
The Neuron-Glia Unit in Neuropathology: Is it a Double-Edged Sword? | Aschner, Michael; Aschner, Yael; Sonnewald, Ursula | R01ES007331, R01ES010563 | No Junkan Taisha (2003) | 31190696 | 2003 |
Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints. | Weber, Sarah; Dorman, David C; Lash, Lawrence H; Erikson, Keith; Vrana, Kent E; Aschner, Micha ... | R01ES007331, R01ES010563 | Neurotoxicology (2002 Jul) | 12224758 | 2002 |
Effects of manganese on oxidative stress in CATH.a cells. | Worley, Cynthia G; Bombick, David; Allen, Jeffrey W; Suber, R Lee; Aschner, Michael | R01ES007331, R01ES010563 | Neurotoxicology (2002 Jul) | 12224756 | 2002 |
The uptake of manganese in brain endothelial cultures. | Aschner, Michael; Shanker, Gouri; Erikson, Keith; Yang, Jian; Mutkus, Lysette A | R01ES007331, R01ES010563 | Neurotoxicology (2002 Jul) | 12224757 | 2002 |
Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-condition ... | Yang, J; Mutkus, L A; Sumner, D; Stevens, J T; Eldridge, J C; Strandhoy, J W; Aschner, M | R01ES007331, R01ES010563 | Brain Res Mol Brain Res (2001 Dec 16) | 11744161 | 2001 |