Superfund Research Program
Research Support Core: Analytical Core
Project Leader: Keri C. Hornbuckle
Co-Investigator: Hans-Joachim Lehmler
Grant Number: P42ES013661
Funding Period: 2006-2025
Project-Specific Links
Final Progress Reports
The Analytical Core of the ISRP provides assistance to the Project Directors and their staff in measuring PCB congeners and their metabolites in laboratory animals, human blood, plant tissues, water, sediments, air, and other natural and engineered systems. The core also provide advice and assistance in the development of laboratory experiments that involve PCBs, designing field studies for PCBs in the environment, in determining auxiliary measurements (porosity, organic carbon and lipid contents, bulk measurements), and in the interpretation of the PCB data.
In 2009, the Analytical Core assisted the Oxidative Stress and PCB Exposure in Mammalian Cells project by analyzing PCB11 and hydroxylated PCB11 in cell tissues and blood, assisted the Atmospheric Sources of PCB Congeners project by analyzing air samples for all 209 PCBs in over 400 environmental samples; assisted the Phytoremediation to Degrade Airborne PCB Congeners from Soil and Groundwater Sources project by analyzing PCBs and assisting the measurement of OH-PCBs in plant tissue and laboratory media; assisted the Airborne Exposure to Semi-volatile Organic Pollutants project by analyzing PCBs in animal tissues, human blood serum, laboratory solutions and sorbents. The core also collaborated with the Inhalation Toxicology core and the Synthesis Core in developing a synthetic PCB mixture that resembled the PCBs found in Chicago air and by measuring and modeling the volatilization of PCBs from a pure PCB liquid.