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Michigan State University: Dataset Details, ID=GSE97636

Superfund Research Program

TCDD-Elicited Steatosis: The Role of Aryl Hydrocarbon Receptor Regulation in Lipid Uptake, Metabolism, and Transport

Project Leader: Timothy R. Zacharewski
Grant Number: P42ES004911
Funding Period: 2006-2021

Project-Specific Links

Title: AHR ChIP-Seq of male mouse liver following 2 hour TCDD exposure

Accession Number: GSE97636

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE97636

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): ChIP-Seq, Genome binding/occupancy profiling by high throughput sequencing

Organism(s): Mus musculus

Summary: Aryl hydrocarbon receptor ChIP-Seq performed in livers of female mice gavaged with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for 2hrs

Publication(s) associated with this dataset:
  • Nault R, Fader KA, Kirby MP, Ahmed S, Matthews J, Jones AD, Lunt SY, Zacharewski TR. 2016. Pyruvate kinase isoform switching and hepatic metabolic reprogramming by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci 149(2):358-371. doi:10.1093/toxsci/kfv245 PMID:26582802 PMCID:PMC4900217
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