Title: Patterns of aberrant DNA methylation after toxicant-induced malignant transformation (MeDIP-chip dataset 1)

Accession Number: GSE38926

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38926

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Methylation profiling by genome tiling array

Organism(s): Homo sapiens

Summary: Aberrant DNA methylation is frequently observed in cancer. The aim of this study was to determine how DNA methylation is changed after toxicant-induced malignant transformation. This study also puts the DNA methylation changes into context with respect to the aberrant DNA methylation events that occur in bladder and prostate carcinogenesis not associated with toxicant exposure.

Publication(s) associated with this dataset:

• Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher BW. 2013. Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation. Epigenetics 8(10):1080–1088. doi:10.4161/epi.25926 PMID:23974009 PMCID:PMC3891689