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University of North Carolina-Chapel Hill: Dataset Details, ID=GSE72079

Superfund Research Program

Elucidating Risks: From Exposure and Mechanism to Outcome

Center Director: Rebecca C. Fry
Grant Number: P42ES005948
Funding Period: 1992-2018
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Title: Transcriptional profiling of inducible GATA6L-overexpressing HT-29 cells stimulated with TNF

Accession Number: GSE72079

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE72079

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Homo sapiens

Summary: The objective of this study was to investigate the role of GATA6L with or without TNF stimulation. Microarrays were used to capture the transcriptional response to GATA6L overexpression at intermediate times after TNF stimulation.

Publication(s) associated with this dataset:
  • Chitforoushzadeh Z, Ye Z, Sheng Z, LaRue S, Fry RC, Lauffenburger DA, Janes KA. 2016. TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors. Sci Signal 9(431):ra59. doi:10.1126/scisignal.aad3373 PMID:27273097 PMCID:PMC4914393
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