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Your Environment. Your Health.

Program Publications: University of North Carolina-Chapel Hill: Elucidating Risks: From Exposure and Mechanism to Outcome

Superfund Research Program

Elucidating Risks: From Exposure and Mechanism to Outcome

Center Director: Rebecca C. Fry
Grant Number: P42ES005948
Funding Period: 1992-2018
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Publications

2019

  • Meakin C, Martin EM, Szilagyi JT, Nylander-French LA, Fry RC. 2019. Inorganic Arsenic as an Endocrine Disruptor: Modulation of the Glucocorticoid Receptor Pathway in Placental Cells via CpG Methylation. Chem Res Toxicol 32(3):493-499. doi:10.1021/acs.chemrestox.8b00352 PMID:30746931

2018

  • Adebambo OA, Shea D, Fry RC. 2018. Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-beta) pathways in placental JEG-3 trophoblast cells via reactive oxygen species. Toxicol Appl Pharmacol 342:108-115. doi:10.1016/j.taap.2018.01.010 PMID:29408318
  • Archambault JM, Prochazka ST, Cope W, Shea D, Lazaro P. 2018. Polycyclic aromatic hydrocarbons in surface waters, sediments, and unionid mussels: relation to road crossings and implications for chronic mussel exposure. Hydrobiologia 810:465-476. doi:10.1007/s10750-017-3101-y
  • Balik-Meisner M, Truong L, Scholl EH, La Du JK, Tanguay RL, Reif DM. 2018. Elucidating gene-by-environment interactions associated with differential susceptibility to chemical exposure. Environ Health Perspect 126:8. doi:10.1289/ehp2662 PMID:29968567
  • Brewster CS, Sharma VK, Cizmas LH, McDonald TJ. 2018. Occurrence, distribution and composition of aliphatic and polycyclic aromatic hydrocarbons in sediment cores from the Lower Fox River, Wisconsin, US. Environ Sci Pollut Res Int 25(5):4974-4988. doi:10.1007/s11356-017-0819-z PMID:29204943 PMCID:PMC5823782
  • Buttermore EN, Cope W, Kwak TJ, Cooney P, Shea D, Lazaro P. 2018. Contaminants in tropical island streams and their biota. Environ Res 161:615-623. doi:10.1016/j.envres.2017.11.053 PMID:29257981
  • Cichocki JA, Luo Y, Furuya S, Venkatratnam A, Konganti K, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I. 2018. Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice. Toxicol Sci 167(1):126-137. doi:10.1093/toxsci/kfy223 PMID:30202895 PMCID:PMC6317418
  • Dalaijamts C, Cichocki JA, Luo Y, Rusyn I, Chiu WA. 2018. Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice. Toxicol Appl Pharmacol 352:142-152. doi:10.1016/j.taap.2018.05.033 PMID:29857080 PMCID:PMC6051410
  • Fry RC, Martin EM. 2018. Environmental influences on the epigenome: exposure- associated DNA methylation in human populations. Annu Rev Public Health 39:303-333. doi:10.1146/annurev-publhealth-040617-014629 PMID:29328878
  • Gray K. 2018. From content knowledge to community change: A review of representations of environmental health literacy. Int J Environ Res Public Health 15(3):466. doi:10.3390/ijerph15030466 PMID:29518955 PMCID:PMC5877011
  • Haine D. 2018. The exposome: making chemical exposures relevant to biology instruction. Am Biol Teach 80(8):600-607. doi:10.1525/abt.2018.80.8.600
  • Li G, Jima DD, Wright FA, Nobel AB. 2018. HT-eQTL: integrative expression quantitative trait loci analysis in a large number of human tissues. BMC Bioinformatics 19:95. doi:10.1186/s12859-018-2088-3 PMID:29523079
  • Luo Y, Furuya S, Chiu WA, Rusyn I. 2018. Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse. J Toxicol Environ Health A 81:37-52. doi:10.1080/15287394.2017.1408512 PMID:29190187
  • Luo Y, Furuya S, Soldatov VY, Kosyk O, Yoo HS, Fukushima H, Lewis L, Iwata Y, Rusyn I. 2018. Metabolism and toxicity of trichloroethylene and tetrachloroethylene in cytochrome P450 2E1 knockout and humanized transgenic mice. Toxicol Sci doi:10.1093/toxsci/kfy099 PMID:29897530
  • Luo Y, Hsieh N, Soldatow VY, Chiu WA, Rusyn I. 2018. Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strains. Toxicology 409:33-43. doi:10.1016/j.tox.2018.07.012 PMID:30053492 PMCID:PMC6186498
  • McEachran AD, Hedgespeth ML, Newton SR, McMahen R, Strynar M, Shea D, Nichols EG. 2018. Comparison of emerging contaminants in receiving waters downstream of a conventional wastewater treatment plant and a forest-water reuse system. Environ Sci Pollut Res Int doi:10.1007/s11356-018-1505-5 PMID:29460251
  • Smeester L, Fry RC. 2018. Long-Term Health Effects and Underlying Biological Mechanisms of Developmental Exposure to Arsenic. Curr Environ Health Rep 5(1):134-144. doi:10.1007/s40572-018-0184-1 PMID:29411302
  • Tian Z, Vila J, Yu M, Bodnar WM, Aitken MD. 2018. Tracing the biotransformation of polycyclic aromatic hydrocarbons in contaminated soil using stable isotope-assisted metabolomics. Environ Sci Technol Lett 5(2):103-109. doi:10.1021/acs.estlett.7b00554
  • Tilley SK, Martin EM, Smeester L, Joseph RM, Kuban KC, Heeren T, Dammann OU, O'Shea TM, Fry RC. 2018. Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life. PLoS One 13:16. doi:10.1371/journal.pone.0193271 PMID:29513726 PMCID:PMC5841757
  • To K, Fry RC, Reif DM. 2018. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Min 11:12. doi:10.1186/s13040-018-0169-5 PMID:29942350 PMCID:PMC5998548

2017

  • Archambault JM, Bergeron CM, Cope W, Lazaro P, Leonard JA, Shea D. 2017. Assessing toxicity of contaminants in riverine suspended sediments to freshwater mussels. Environ Toxicol Chem 36(2):395-407. doi:10.1002/etc.3540 PMID:27349213 PMCID:PMC5858922
  • Bommarito P, Martin EM, Fry RC. 2017. Effects of prenatal exposure to endocrine disruptors and toxic metals on the fetal epigenome. Epigenomics 9:333-350. doi:10.2217/epi-2016-0112 PMID:28234024
  • Bommarito P, Martin EM, Smeester L, Palys T, Baker E, Karagas MR, Fry RC. 2017. Fetal-sex dependent genomic responses in the circulating lymphocytes of arsenic-exposed pregnant women in New Hampshire. Reprod Toxicol 73:184-195. doi:10.1016/j.reprotox.2017.07.023 PMID:28793237
  • Brooks SA, Fry RC. 2017. Cadmium inhibits placental trophoblast cell migration via miRNA regulation of the transforming growth factor beta (TGF-beta) pathway. Food Chem Toxicol 109:721-726. doi:10.1016/j.fct.2017.07.059 PMID:28774740 PMCID:PMC5656529
  • Chibwe L, Davie-Martin C, Aitken MD, Hoh E, Simonich SL. 2017. Identification of polar transformation products and high molecular weight polycyclic aromatic hydrocarbons (PAHs) in contaminated soil following bioremediation. Sci Total Environ 599-600:1099-1107. doi:10.1016/j.scitotenv.2017.04.190 PMID:28511355
  • Cichocki JA, Furuya S, Konganti K, Luo Y, McDonald TJ, Iwata Y, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I. 2017. Impact of nonalcoholic fatty liver disease on toxicokinetics of tetrachloroethylene in mice. J Pharmacol Exp Ther 361(1):17-28. doi:10.1124/jpet.116.238790 PMID:28148637 PMCID:PMC5363767
  • Cichocki JA, Furuya S, Venkatratnam A, McDonald TJ, Knap A, Wade TL, Sweet S, Chiu WA, Threadgill DW, Rusyn I. 2017. Characterization of variability in toxicokinetics and toxicodynamics of tetrachloroethylene using the collaborative cross mouse population. Environ Health Perspect 125(5):057006. doi:10.1289/ehp788 PMID:28572074 PMCID:PMC5726344
  • Corteselli EM, Aitken MD, Singleton D. 2017. Description of Immundisolibacter cernigliae gen. nov., sp. nov., a high-molecular-weight polycyclic aromatic hydrocarbon-degrading bacterium within the class Gammaproteobacteria, and proposal of Immundisolibacterales ord. nov. and Immundisolibacteraceae fam. nov. Int J Syst Evol Microbiol 67:925-931. doi:10.1099/ijsem.0.001714 PMID:27926817 PMCID:PMC5817195
  • Corteselli EM, Aitken MD, Singleton D. 2017. Rugosibacter aromaticivorans gen nov, sp nov, a bacterium within the family Rhodocyclaceae, isolated from contaminated soil, capable of degrading aromatic compounds. Int J Syst Evol Microbiol 67(2):311-318. doi:10.1099/ijsem.0.001622 PMID:27902243
  • Edrissi B, Taghizadeh K, Moeller BC, Yu R, Kracko D, Doyle-Eisele M, Swenberg JA, Dedon PC. 2017. N6-Formyllysine as a Biomarker of Formaldehyde Exposure: Formation and Loss of N6-Formyllysine in Nasal Epithelium in Long-Term, Low-Dose Inhalation Studies in Rats. Chem Res Toxicol 30(8):1572-1576. doi:10.1021/acs.chemrestox.7b00075 PMID:28692800 PMCID:PMC5807069
  • Franceschini N, Fry RC, Balakrishnan P, Navas-Acien A, Oliver-Williams C, Howard AG, Cole SA, Haack KW, Lange EM, Howard BV, Best LG, Francesconi KA, Umans JG, Tellez-Plaza M. 2017. Cadmium body burden and increased blood pressure in middle-aged American Indians: the Strong Heart Study. J Hum Hypertens 31(3):225-230. doi:10.1038/jhh.2016.67 PMID:27629244 PMCID:PMC5299034
  • Gao L, Mutlu E, Collins LB, Walker N, Hartwell HJ, Olson J, Sun W, Gold A, Ball LM, Swenberg JA. 2017. DNA product formation in female Sprague-Dawley rats following polyhalogenated aromatic hydrocarbon (PHAH) exposure. Chem Res Toxicol 30(3):794-803. doi:10.1021/acs.chemrestox.6b00368 PMID:28207250 PMCID:PMC5363288
  • Grimm FA, Russell WK, Luo Y, Iwata Y, Chiu WA, Roy T, Boogaard PJ, Ketelslegers HB, Rusyn I. 2017. Grouping of petroleum substances as example UVCBs by ion mobility-mass spectrometry to enable chemical composition-based read-across. Environ Sci Technol 51:7197-7207. doi:10.1021/acs.est.6b06413 PMID:28502166 PMCID:PMC5627358
  • Huang MC, Douillet C, Su M, Zhou K, Wu T, Chen W, Galanko JA, Drobna Z, Saunders RJ, Martin EM, Fry RC, Jia W, Styblo M. 2017. Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Arch Toxicol 91(1):189-202. doi:10.1007/s00204-016-1676-0 PMID:26883664 PMCID:PMC4987274
  • Klaus V, Bastek H, Damme K, Collins LB, Frotschl R, Benda N, Lutter D, Ellinger-Ziegelbauer H, Swenberg JA, Dietrich DR, Stemmer K. 2017. Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. Arch Toxicol 91(10):3427-3438. doi:10.1007/s00204-017-1953-6 PMID:28349193 PMCID:PMC5617782
  • Laine JE, Bailey KA, Olshan A, Smeester L, Drobna Z, Styblo M, Douillet C, Garcia-Vargas G, Rubio-Andrade M, Pathmasiri W, McRitchie S, Sumner SJ, Fry RC. 2017. Neonatal metabolomic profiles related to prenatal arsenic exposure. Environ Sci Technol 51(1):625-633. doi:10.1021/acs.est.6b04374 PMID:27997141
  • Martin EM, Smeester L, Bommarito P, Grace MR, Boggess K, Kuban K, Karagas MR, Marsit CJ, O'Shea TM, Fry RC. 2017. Sexual epigenetic dimorphism in the human placenta: implications for susceptibility during the prenatal period. Epigenomics 9(3):267-278. doi:10.2217/epi-2016-0132 PMID:28234023 PMCID:PMC5331919
  • Martin EM, Styblo M, Fry RC. 2017. Genetic and epigenetic mechanisms underlying arsenic-associated diabetes mellitus: a perspective of the current evidence. Epigenomics 9(5):doi:10.2217/epi-2016-0097 PMID:28470093 PMCID:PMC5480787
  • McEachran AD, Shea D, Nichols EG. 2017. Pharmaceuticals in a temperate forest-water reuse system. Sci Total Environ 581-582:705-714. doi:10.1016/j.scitotenv.2016.12.185 PMID:28073640 PMCID:PMC5303553
  • Nakamura J, Shimomoto T, Collins LB, Holley DW, Zhang Z, Barbee JM, Sharma V, Tian X, Kondo T, Uchida K, Yi X, Perkins DO, Willis MS, Gold A, Bultman SJ. 2017. Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes. Sci Rep 7:12. doi:10.1038/s41598-017-11289-8 PMID:28883613 PMCID:PMC5589919
  • Rager JE, Auerbach SS, Chappell G, Martin EM, Thompson CM, Fry RC. 2017. Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort. Chem Res Toxicol 30(10):1911-1920. doi:10.1021/acs.chemrestox.7b00221
  • Shimomoto T, Collins LB, Yi X, Holley DW, Zhang Z, Tian X, Uchida K, Wang C, Horkko S, Bultman SJ, Willis MS, Gold A, Nakamura J. 2017. A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity. PLoS One 12(2):e0172172. doi:10.1371/journal.pone.0172172 PMID:28222187 PMCID:PMC5319763
  • Smeester L, Bommarito P, Martin EM, Recio-Vega R, Gonzalez-Cortes, Olivas-Calderon E, Lantz RC, Fry RC. 2017. Chronic early childhood exposure to arsenic is associated with a TNF-mediated proteomic signaling response. Environ Toxicol Pharmacol 52:183-187. doi:10.1016/j.etap.2017.04.007 PMID:28433805
  • Smeester L, Martin EM, Cable P, Bodnar WM, Boggess K, Vora NL, Fry RC. 2017. Toxic metals in amniotic fluid and altered gene expression in cell‐free fetal RNA. Prenat Diagn 37(13):1364-1366. doi:10.1002/pd.5183 PMID:29111618 PMCID:PMC5766286
  • Tian Z, Gold A, Nakamura J, Zhang Z, Vila J, Singleton D, Collins LB, Aitken MD. 2017. Nontarget Analysis Reveals a Bacterial Metabolite of Pyrene Implicated in the Genotoxicity of Contaminated Soil after Bioremediation. Environ Sci Technol 51(12):7091-7100. doi:10.1021/acs.est.7b01172 PMID:28510420 PMCID:PMC6309544
  • Tian Z, Vila J, Wang H, Bodnar WM, Aitken MD. 2017. Diversity and Abundance of High-Molecular-Weight Azaarenes in PAH-Contaminated Environmental Samples. Environ Sci Technol 51:14047-14054. doi:10.1021/acs.est.7b03319 PMID:29160699
  • Tilley SK, Joseph RM, Kuban KC, Dammann OU, O'Shea TM, Fry RC. 2017. Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes. PLoS One 12(5):e0176953. doi:10.1371/journal.pone.0176953 PMID:28493900 PMCID:PMC5426658
  • Tilley SK, Reif DM, Fry RC. 2017. Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina. Environ Int 101:19-26. doi:10.1016/j.envint.2016.10.006 PMID:28153528 PMCID:PMC5351294
  • Tomlinson MS, Bommarito P, Martin EM, Smeester L, Fichorova RN, Onderdonk AB, Kuban KC, O'Shea TM, Fry RC. 2017. Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes. PLoS One 12:13. doi:10.1371/journal.pone.0188664 PMID:29240761 PMCID:PMC5730116
  • Venkatratnam A, Furuya S, Kosyk O, Gold A, Bodnar WM, Konganti K, Threadgill DW, Gillespie DA, Aylor DL, Wright FA, Chiu WA, Rusyn I. 2017. Editor's Highlight: Collaborative Cross mouse population enables refinements to characterization of the variability in toxicokinetics of trichloroethylene and provides genetic evidence for the role of PPAR pathway in its oxidative metabolism. Toxicol Sci 158(1):48-62. doi:10.1093/toxsci/kfx065 PMID:28369613
  • Vora NL, Smeester L, Boggess K, Fry RC. 2017. Investigating the role of fetal gene expression in preterm birth. Reprod Sci 24:824-828. doi:10.1177/1933719116670038 PMID:27678095
  • Zhang G, Roell K, Truong L, Tanguay RL, Reif DM. 2017. A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicol Appl Pharmacol 314:109-117. doi:10.1016/j.taap.2016.11.010 PMID:27884602 PMCID:PMC5224523
  • Zhou Y, Cichocki JA, Soldatow VY, Scholl EH, Gallins P, Jima DD, Yoo HS, Chiu WA, Wright FA, Rusyn I. 2017. Editor's highlight: comparative dose-response analysis of liver and kidney transcriptomic effects of trichloroethylene and tetrachloroethylene in B6C3F1 mouse. Toxicol Sci 160(1):95-110. doi:10.1093/toxsci/kfx165 PMID:28973375 PMCID:PMC5837274

2016

  • Adrion AC, Nakamura J, Shea D, Aitken MD. 2016. Screening nonionic surfactants for enhanced biodegradation of polycyclic aromatic hydrocarbons remaining in soil after conventional biological treatment. Environ Sci Technol 50(7):3838-3845. doi:10.1021/acs.est.5b05243 PMID:26919662 PMCID:PMC4973855
  • Adrion AC, Singleton D, Nakamura J, Shea D, Aitken MD. 2016. Improving polycyclic aromatic hydrocarbon biodegradation in contaminated soil through low-level surfactant addition after conventional bioremediation. Environ Eng Sci 33(9):659-670. doi:10.1089/ees.2016.0128 PMID:27678476 PMCID:PMC5031096
  • Bailey KA, Smith AH, Tokar EJ, Graziano JH, Kim KW, Navasumrit P, Ruchirawat K, Thiantanawat A, Suk WA, Fry RC. 2016. Mechanisms underlying latent disease risk associated with early-life arsenic exposure: current research trends and scientific gaps. Environ Health Perspect 124(2):170-175. doi:10.1289/ehp.1409360 PMID:26115410 PMCID:PMC4749078
  • Bassig BA, Zhang L, Vermeulen R, Tang X, Li G, Hu W, Guo W, Purdue MP, Yin S, Rappaport SM, Shen M, Ji Z, Qiu C, Ge Y, Hosgood H, Reiss B, Wu B, Xie Y, Li L, Yue F, Freeman LB, Blair AE, Hayes RB, Huang H, Smith MT, Rothman N, Lan Q. 2016. Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene. Carcinogenesis 37(7):692-700. doi:10.1093/carcin/bgw053 PMID:27207665 PMCID:PMC4936387
  • Bommarito P, Fry RC. 2016. Developmental windows of susceptibility to inorganic arsenic: a survey of current toxicologic and epidemiologic data. Toxicol Res (Camb) 5:1503-1511. doi:10.1039/c6tx00234j
  • Brooks SA, Martin EM, Smeester L, Grace MR, Boggess K, Fry RC. 2016. miRNAs as common regulators of the transforming growth factor (TGF)-β pathway in the preeclamptic placenta and cadmium-treated trophoblasts: Links between the environment, the epigenome and preeclampsia. Food Chem Toxicol 98(PtA):50-57. doi:10.1016/j.fct.2016.06.023 PMID:27375191 PMCID:PMC5156314
  • Chappell G, Silva GO, Uehara T, Pogribny IP, Rusyn I. 2016. Characterization of copy number alterations in a mouse model of fibrosis-associated hepatocellular carcinoma reveals concordance with human disease. Cancer Med 5(3):574-585. doi:10.1002/cam4.606 PMID:26778414 PMCID:PMC4799957
  • Chitforoushzadeh Z, Ye Z, Sheng Z, LaRue S, Fry RC, Lauffenburger DA, Janes KA. 2016. TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors. Sci Signal 9(431):ra59. doi:10.1126/scisignal.aad3373 PMID:27273097 PMCID:PMC4914393
  • Cichocki JA, Guyton KZ, Guha N, Chiu WA, Rusyn I, Lash LH. 2016. Target organ metabolism, toxicity, and mechanisms of trichloroethylene and perchloroethylene: key similarities, differences, and data gaps. J Pharmacol Exp Ther 359(1):110-123. doi:10.1124/jpet.116.232629 PMID:27511820 PMCID:PMC5034707
  • Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton K, DeVito MJ, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper SC, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. 2016. The next generation of risk assessment multi-year study-highlights of findings, applications to risk assessment, and future directions. Environ Health Perspect 124(11):1671-1682. doi:10.1289/ehp233 PMID:27091369 PMCID:PMC5089888
  • Drobna Z, Martin EM, Kim K, Smeester L, Bommarito P, Rubio-Andrade M, Garcia-Vargas GG, Styblo M, Zou F, Fry RC. 2016. Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis. Reprod Toxicol 61:28-38. doi:10.1016/j.reprotox.2016.02.017 PMID:26928318 PMCID:PMC4970429
  • Gmeiner WH, Gearhart PJ, Pommier Y, Nakamura J. 2016. F10 cytotoxicity via topoisomerase I cleavage complex repair consistent with a unique mechanism for thymineless death. Future Oncol 12(19):2183-2188. doi:10.2217/fon-2016-0127 PMID:27333295
  • Grimm FA, Iwata Y, Sirenko O, Chappell G, Wright FA, Reif DM, Braisted JA, Gerhold D, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde A, Rusyn I. 2016. A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives. Green Chem 18(16):4407-4419. doi:10.1039/c6gc01147k PMID:28035192 PMCID:PMC5179981
  • Gutierrez T, Berry D, Teske A, Aitken MD. 2016. Clinical features of functional (psychogenic) eye movement disorders. Journal of Neurology, Neurosurgery & Psychiatry 87(12):1389-1392. doi:10.1136/jnnp-2016-313608 PMID:27683918
  • Gutierrez T, Berry D, Teske A, Aitken MD. 2016. Enrichment of fusobacteria in sea surface oil slicks from the Deepwater Horizon oil spill. Microorganisms 4(3):doi:10.3390/microorganisms4030024 PMID:27681918 PMCID:PMC5039584
  • Harrington JM, Young DJ, Fry RC, Weber FX, Sumner S, Levine KE. 2016. Validation of a metallomics analysis of placenta tissue by inductively-coupled plasma mass spectrometry. Biol Trace Elem Res 169(2):164-173. doi:10.1007/s12011-015-0431-3 PMID:26155965 PMCID:PMC4763796
  • Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J. 2016. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget 7(37):59795-59808. doi:10.18632/oncotarget.10928 PMID:27486975
  • Jat P, Serre ML. 2016. Bayesian Maximum Entropy space/time estimation of surface water chloride in Maryland using river distances. Environ Pollut 219:1148-1155. doi:10.1016/j.envpol.2016.09.020 PMID:27616646
  • Korfmacher KS, Pettibone KG, Gray K, Newman OD. 2016. Collaborating for systems change: a social science framework for academic roles in community partnerships. New Solut 26(3):429-457. doi:10.1177/1048291116662680 PMID:27540024 PMCID:PMC5315683
  • Lai Y, Yu R, Hartwell HJ, Moeller BC, Bodnar WM, Swenberg JA. 2016. Measurement of endogenous versus exogenous formaldehyde-induced DNA-protein crosslinks in animal tissues by stable isotope labeling and ultrasensitive mass spectrometry. Cancer Res 76(9):2652-2661. doi:10.1158/0008-5472.CAN-15-2527 PMID:26984759 PMCID:PMC4879886
  • Laine JE, Fry RC. 2016. A systems toxicology-based approach reveals biological pathways dysregulated by prenatal arsenic exposure. Ann Glob Health 82(1):189-196. doi:10.1016/j.aogh.2016.01.015 PMID:27325076 PMCID:PMC4989910
  • Marrone AK, Shpyleva S, Chappell G, Tryndyak VP, Uehara T, Beland FA, Rusyn I, Pogribny IP. 2016. Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice. Mol Carcinog 55(5):808-817. doi:10.1002/mc.22323 PMID:25865624
  • Martin EM, Clapp PW, Rebuli ME, Pawlak EA, Glista-Baker E, Benowitz NL, Fry RC, Jaspers I. 2016. E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke. Am J Physiol 311(1):L135-L144. doi:10.1152/ajplung.00170.2016 PMID:27288488 PMCID:PMC4967187
  • Martin EM, Fry RC. 2016. A cross-study analysis of prenatal exposures to environmental contaminants and the epigenome: support for stress-responsive transcription factor occupancy as a mediator of gene-specific CpG methylation patterning. Environ Epigenet 2(1):doi:10.1093/eep/dvv011 PMID:27066266 PMCID:PMC4824001
  • McEachran AD, Shea D, Bodnar WM, Nichols EG. 2016. Pharmaceutical occurrence in groundwater and surface waters in forests land-applied with municipal wastewater. Environ Toxicol Chem 35(4):898-905. doi:10.1002/etc.3216 PMID:26297815 PMCID:PMC4976290
  • Mendez MA, Gonzalez-Horta C, Sanchez-Ramirez B, Ballinas-Casarrubias L, Ceron RH, Morales DV, Baeza Terrazas FA, Ishida MC, Gutierrez-Torres DS, Saunders RJ, Drobna Z, Fry RC, Buse JB, Loomis D, Garcia-Vargas GG, Styblo M. 2016. Chronic exposure to arsenic and markers of cardiometabolic risk: a cross-sectional study in Chihuahua, Mexico. Environ Health Perspect 124(1):104-111. doi:10.1289/ehp.1408742 PMID:26068977 PMCID:PMC4710594
  • Mishamandani S, Gutierrez T, Berry D, Aitken MD. 2016. Response of the bacterial community associated with a cosmopolitan marine diatom to crude oil shows a preference for the biodegradation of aromatic hydrocarbons. Environ Microbiol 18(6):1817-1833. doi:10.1111/1462-2920.12988 PMID:26184578 PMCID:PMC4970210
  • Mutlu E, Gao L, Collins LB, Walker N, Hartwell HJ, Olson J, Sun W, Gold A, Ball LM, Swenberg JA. 2016. Polychlorinated biphenyls induce oxidative DNA adducts in female Sprague-Dawley rats. Chem Res Toxicol 29(8):1335-1344. doi:10.1021/acs.chemrestox.6b00146 PMID:27436759 PMCID:PMC5020703
  • Rappaport SM. 2016. Genetic factors are not the major causes of chronic diseases. PLoS One 11(4):e0154387. doi:10.1371/journal.pone.0154387 PMID:27105432 PMCID:PMC4841510
  • Rusyn I, Knap A. 2016. Environmental exposures due to natural disasters. Rev Environ Health 31(1):89-92. doi:10.1515/reveh-2016-0010 PMID:26982607 PMCID:PMC4913349
  • Sharma V, Collins LB, Chen T, Herr N, Takeda S, Sun W, Swenberg JA, Nakamura J. 2016. Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget 7(18):25377-25390. doi:10.18632/oncotarget.8298 PMID:27015367 PMCID:PMC5041911
  • Singleton D, Adrion AC, Aitken MD. 2016. Surfactant-induced bacterial community changes correlated with increased polycyclic aromatic hydrocarbon degradation in contaminated soil. Appl Microbiol Biotechnol 100(23):10165-10177. doi:10.1007/s00253-016-7867-z PMID:27695967
  • Singleton D, Dickey AN, Scholl EH, Wright FA, Aitken MD. 2016. Complete genome sequence of a bacterium representing a deep uncultivated lineage within the gammaproteobacteria associated with the degradation of polycyclic aromatic hydrocarbons. Genome Announc 4(5):e01086-e01116. doi:10.1128/genomeA.01086-16 PMID:27795254 PMCID:PMC5054325
  • Sollome JJ, Martin EM, Sethupathy P, Fry RC. 2016. Environmental contaminants and microRNA regulation: transcription factors as regulators of toxicant-altered microRNA expression. Toxicol Appl Pharmacol 312:61-66. doi:10.1016/j.taap.2016.06.009 PMID:27292125 PMCID:PMC5145741
  • Swenberg JA, Lai Y, Yu R, Sharma V, Moeller BC, Hartwell HJ, MacDonald Gibson J, Nakamura J. 2016. The role of endogenous versus exogenous DNA damage in risk assessment. In: Thresholds of genotoxic carcinogens: from mechanisms to regulation. Elsevier, pp.83-102.
  • Tian X, Patel K, Ridpath JR, Chen Y, Zhou Y, Neo D, Clement JM, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA, Nakamura J. 2016. Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium. PLoS One 11(12):e0167503. doi:10.1371/journal.pone.0167503 PMID:27907204 PMCID:PMC5132242
  • Vora NL, Smeester L, Boggess K, Fry RC. 2016. Increased fetal inflammatory gene expression in cell-free fetal RNA is associated with earlier gestational age at birth. Journal of Women's Health 25:977-978.
  • Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. 2016. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature 532(7599):329-333. doi:10.1038/nature17640 PMID:27027282 PMCID:PMC4977844
  • Xu X, Drobna Z, Voruganti VS, Barron K, Gonzalez-Horta C, Sanchez-Ramirez B, Ballinas-Casarrubias L, Ceron RH, Morales DV, Baeza Terrazas FA, Ishida MC, Gutierrez-Torres DS, Saunders RJ, Crandell J, Fry RC, Loomis D, Garcia-Vargas G, Del Razo LM, Styblo M, Mendez MA. 2016. Association between variants in arsenic (+3 oxidation state) methyltranserase (AS3MT) and urinary metabolites of inorganic arsenic: role of exposure level. Toxicol Sci 153(1):112-123. doi:10.1093/toxsci/kfw112 PMID:27370415 PMCID:PMC5808745
  • Zabinski JW, Garcia-Vargas GG, Rubio-Andrade M, Fry RC, MacDonald Gibson J. 2016. Advancing dose-response assessment methods for environmental regulatory impact analysis: a Bayesian belief network approach applied to inorganic arsenic. Environ Sci Technol Lett 3(5):200-204. doi:10.1021/acs.estlett.6b00076 PMID:27747248 PMCID:PMC5063306

2015

  • Abdo N, Wetmore BA, Chappell G, Shea D, Wright FA, Rusyn I. 2015. In vitro screening for population variability in toxicity of pesticide-containing mixtures. Environ Int 85:147-155. doi:10.1016/j.envint.2015.09.012 PMID:26386728 PMCID:PMC4773193
  • Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou Y, Jack J, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif A, Austin CP, Tice RR, Rusyn I, Wright FA. 2015. Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. Environ Health Perspect 123(5):458-466. doi:10.1289/ehp.1408775 PMID:25622337 PMCID:PMC4421772
  • Adebambo OA, Ray PD, Shea D, Fry RC. 2015. Toxicological responses of environmental mixtures: Environmental metal mixtures display synergistic induction of metal-responsive and oxidative stress genes in placental cells. Toxicol Appl Pharmacol 289(3):534-541. doi:10.1016/j.taap.2015.10.005 PMID:26472158 PMCID:PMC4763604
  • Chibwe L, Geier MC, Nakamura J, Tanguay RL, Aitken MD, Massey Simonich SL. 2015. Aerobic bioremediation of PAH contaminated soil results in increased genotoxicity and developmental toxicity. Environ Sci Technol 49(23):13889-13898. doi:10.1021/acs.est.5b00499 PMID:26200254 PMCID:PMC4666737
  • Eduati F, Mangravite LM, Wang T, Tang H, Bare J, Huang R, Norman T, Kellen M, Menden MP, Yang J, Zhan X, Zhong R, Xiao G, Xia M, Abdo N, Kosyk O, Friend S, Dearry A, Simeonov A, Tice RR, Rusyn I, Wright FA, Stolovitzky G, Xie Y. 2015. Prediction of human population responses to toxic compounds by a collaborative competition. Nat Biotechnol 33(9):933-940. PMID:26258538
  • Edwards SE, Maxson P, Miranda ML, Fry RC. 2015. Cadmium levels in a North Carolina cohort: Identifying risk factors for elevated levels during pregnancy. J Expo Sci Environ Epidemiol 25(4):427-432. doi:10.1038/jes.2014.53 PMID:25073434 PMCID:PMC4312255
  • Gona S, Sanders AP, Miranda ML, Fry RC. 2015. Prenatal exposure to cadmium and cotinine and CpG island DNA methylation in mother-infant pairs. Genom Data 5:378-380. doi:10.1016/j.gdata.2015.07.001 PMID:26295018 PMCID:PMC4538703
  • Grimm FA, Iwata Y, Sirenko O, Bittner M, Rusyn I. 2015. High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes. Assay Drug Dev Technol 13(9):529-546. doi:10.1089/adt.2015.659 PMID:26539751 PMCID:PMC4652224
  • Hashimoto K, Takeda S, Swenberg JA, Nakamura J. 2015. Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cells. Mutagenesis 30(6):821-828. doi:10.1093/mutage/gev042 PMID:26085549 PMCID:PMC4723676
  • Hirota K, Yoshikiyo K, Guilbaud G, Tsurimoto T, Murai J, Tsuda M, Phillips LG, Narita T, Nishihara K, Kobayashi K, Yamada K, Nakamura J, Pommier Y, Lehmann A, Sale JE, Takeda S. 2015. The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ. Nucleic Acids Res 43(3):1671-1683. doi:10.1093/nar/gkv023 PMID:25628356 PMCID:PMC4330384
  • Laine JE, Bailey KA, Rubio-Andrade M, Olshan A, Smeester L, Drobna Z, Herring AH, Styblo M, Garcia-Vargas GG, Fry RC. 2015. Maternal arsenic exposure, arsenic methylation efficiency, and birth outcomes in the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Mexico. Environ Health Perspect 123(2):186-192. doi:10.1289/ehp.1307476 PMID:25325819 PMCID:PMC4314242
  • Laine JE, Ray PD, Bodnar WM, Cable PH, Boggess K, Offenbacher S, Fry RC. 2015. Placental cadmium levels are associated with increased preeclampsia risk. PLoS One 10(9):e0139341. doi:10.1371/journal.pone.0139341 PMID:26422011 PMCID:PMC4589375
  • Martin EA, Gonzalez-Horta C, Rager JE, Bailey KA, Sanchez-Ramirez B, Ballinas-Casarrubias L, Ishida MC, Gutierrez-Torres DS, Ceron RH, Morales DV, Baeza Terrazas FA, Saunders RJ, Drobna Z, Mendez MA, Buse JB, Loomis D, Jia W, Garcia-Vargas GG, Del Razo LM, Styblo M, Fry RC. 2015. Metabolomic characteristics of arsenic-associated diabetes in a prospective cohort in Chihuahua, Mexico. Toxicol Sci 144(2):338-346. doi:10.1093/toxsci/kfu318 PMID:25577196 PMCID:PMC4372663
  • Martin EA, Ray PD, Smeester L, Grace MR, Boggess K, Fry RC. 2015. Epigenetics and preeclampsia: defining functional epimutations in the preeclamptic placenta related to the TGF-β pathway. PLoS One 10(10):e0141294. doi:10.1371/journal.pone.0141294 PMID:26510177 PMCID:PMC4624949
  • Ortega-Calvo JJ, Harmsen J, Parsons JR, Semple KT, Aitken MD, Ajao C, Eadsforth C, Galay-Burgos M, Naidu R, Oliver R, Peijnenburg WJ, Rombke J, Streck G, Versonnen B. 2015. From bioavailability science to regulation of organic chemicals. Environ Sci Technol 49(17):10255-10264. doi:10.1021/acs.est.5b02412 PMID:26230485
  • Pearce N, Blair AE, Vineis P, Ahrens W, Andersen A, Anto JM, Armstrong BK, Baccarelli A, Beland FA, Berrington A, Bertazzi PA, Birnbaum LS, Brownson RC, Bucher JR, Cantor KP, Cardis E, Cherrie JW, Christiani DC, Cocco P, Coggon D, Comba P, Demers PA, Dement JM, Douwes J, Eisen EA, Engel LS, Fenske RA, Fleming LE, Fletcher T, Fontham E, Forastiere F, Frentzel-Beyme R, Fritschi L, Gerin M, Goldberg M, Grandjean P, Grimsrud TK, Gustavsson P, Haines A, Hartge P, Hansen J, Hauptmann M, Heederik D, Hemminki K, Hemon D, Hertz-Picciotto I, Hoppin JA, Huff J, Jarvholm B, Kang D, Karagas MR, Kjaerheim K, Kjuus H, Kogevinas M, Kriebel D, Kristensen P, Kromhout H, Laden F, Lebailly P, LeMasters G, Lubin JH, Lynch CF, Lynge E, Mannetje A, McMichael AJ, McLaughlin J, Marrett L, Martuzzi M, Merchant JA, Merler E, Merletti F, Miller A, Mirer F, Monson RR, Nordby K, Olshan A, Parent M, Perera F, Perry MJ, Pesatori AC, Pirastu R, Porta M, Pukkala E, Rice C, Richardson DB, Ritter L, Ritz B, Ronckers CM, Rushton L, Rusiecki JA, Rusyn I, Samet JM, Sandler DP, de Sanjose S, Schernhammer E, Costantini A, Seixas N, Shy C, Siemiatycki J, Silverman DT, Simonato L, Smith AH, Smith MT, Spinelli JJ, Spitz MR, Stallones L, Stayner LT, Steenland K, Stenzel M, Stewart BW, Stewart P, Symanski E, Terracini B, Tolbert PE, Vainio H, Vena J, Vermeulen R, Victora CG, Ward EM, Weinberg CR, Weisenburger DD, Wesseling C, Weiderpass E, Zahm SH. 2015. IARC monographs: 40 years of evaluating carcinogenic hazards to humans. Environ Health Perspect 123(6):507-514. doi:10.1289/ehp.1409149 PMID:25712798 PMCID:PMC4455595
  • Pontel LB, Rosado IV, Burgos-Barragan G, Arends MJ, Chandrasekaran G, Broecker V, Liu L, Swenberg JA, Crossan GP, Patel KJ. 2015. Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen. Mol Cell 60(1):177-188. doi:10.1016/j.molcel.2015.08.020 PMID:26412304 PMCID:PMC4595711
  • Rager JE, Tilley SK, Tulenko SE, Smeester L, Ray PD, Yosim A, Currier JM, Ishida MC, del Carmen Gonzalez-Horta M, Sanchez-Ramirez B, Ballinas-Casarrubias L, Gutierrez-Torres DS, Drobna Z, Del Razo LM, Garcia-Vargas GG, Kim WY, Zhou Y, Wright FA, Styblo M, Fry RC. 2015. Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer. Chem Res Toxicol 28(6):1144-1155. doi:10.1021/tx500393y PMID:26039340 PMCID:PMC4748849
  • Rodgers-Vieira EA, Zhang Z, Adrion AC, Gold A, Aitken MD. 2015. Identification of anthraquinone-degrading bacteria in soil contaminated with polycyclic aromatic hydrocarbons. Appl Environ Microbiol 81(11):3775-3781. doi:10.1128/AEM.00033-15 PMID:25819957 PMCID:PMC4421061
  • Rojas D, Rager JE, Smeester L, Bailey KA, Drobna Z, Rubio-Andrade M, Styblo M, Garcia-Vargas GG, Fry RC. 2015. Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes. Toxicol Sci 143(1):97-106. doi:10.1093/toxsci/kfu210 PMID:25304211 PMCID:PMC4274382
  • Singleton D, Dickey AN, Scholl EH, Wright FA, Aitken MD. 2015. Complete genome sequence of a novel bacterium within the family Rhodocyclaceae that degrades polycyclic aromatic hydrocarbons. Genome Announc 3(2):doi:10.1128/genomeA.00251-15 PMID:25858839 PMCID:PMC4392151
  • Vidal AC, Semenova V, Darrah T, Vengosh A, Huang Z, King K, Nye MD, Fry RC, Skaar D, Maguire R, Murtha A, Schildkraut J, Murphy SK, Hoyo C. 2015. Maternal cadmium, iron and zinc levels, DNA methylation and birth weight. BMC Pharmacol Toxicol 16:20. doi:10.1186/s40360-015-0020-2 PMID:26173596 PMCID:PMC4502530
  • Yoo HS, Bradford BU, Kosyk O, Shymonyak S, Uehara T, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I. 2015. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects. J Toxicol Environ Health A 78(1):15-31. doi:10.1080/15287394.2015.958417 PMID:25424544 PMCID:PMC4281929
  • Yoo HS, Bradford BU, Kosyk O, Uehara T, Shymonyak S, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I. 2015. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects. J Toxicol Environ Health A 78(1):32-49. doi:10.1080/15287394.2015.958418 PMID:25424545 PMCID:PMC4281933
  • Yoo HS, Cichocki JA, Kim S, Venkatratnam A, Iwata Y, Kosyk O, Bodnar WM, Sweet S, Knap A, Wade TL, Campbell J, Clewell H, Melnyk SB, Chiu WA, Rusyn I. 2015. The contribution of peroxisome proliferator-activated receptor alpha to the relationship between toxicokinetics and toxicodynamics of trichloroethylene. Toxicol Sci 147(2):339-349. doi:10.1093/toxsci/kfv134 PMID:26136231 PMCID:PMC4598794
  • Yu R, Lai Y, Hartwell HJ, Moeller BC, Doyle-Eisele M, Bodnar WM, Starr TB, Swenberg JA. 2015. Formation, accumulation, and hydrolysis of endogenous and exogenous formaldehyde-induced DNA damage. Toxicol Sci 146(1):170-182. doi:10.1093/toxsci/kfv079 PMID:25904104 PMCID:PMC4476463
  • Zhou Y, Wright FA. 2015. Hypothesis testing at the extremes: fast and robust association for high-throughput data. Biostatistics 16(3):611-625. doi:10.1093/biostatistics/kxv007 PMID:25792622 PMCID:PMC4804120

2014

  • Bailey KA, Fry RC. 2014. Arsenic-associated changes to the epigenome: what are the functional consequences?. Curr Environ Health Rep 1:22-34. doi:10.1007/s40572-013-0002-8 PMID:24860721 PMCID:PMC4026129
  • Bailey KA, Fry RC. 2014. Long-term health consequences of prenatal arsenic exposure: links to the genome and the epigenome. Rev Environ Health 29(1-2):9-12. doi:10.1515/reveh-2014-0006 PMID:24552957 PMCID:PMC4049250
  • Bailey KA, Laine JE, Rager JE, Sebastian E, Olshan A, Smeester L, Drobna Z, Styblo M, Rubio-Andrade M, Garcia-Vargas GG, Fry RC. 2014. Prenatal arsenic exposure and shifts in the newborn proteome: interindividual differences in tumor necrosis factor (TNF)-responsive signaling. Toxicol Sci 139(2):328-337. doi:10.1093/toxsci/kfu053 PMID:24675094 PMCID:PMC4031624
  • Chappell G, Kutanzi K, Uehara T, Tryndyak VP, Hong H, Hoenerhoff M, Beland FA, Rusyn I, Pogribny IP. 2014. Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice. Int J Cancer 134:2778-2788. doi:10.1002/ijc.28610 PMID:24242335 PMCID:PMC4209252
  • Chiu WA, Campbell J, Clewell H, Zhou Y, Wright FA, Guyton KZ, Rusyn I. 2014. Physiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse. Environ Health Perspect 122(5):456-463. doi:10.1289/ehp.1307623 PMID:24518055 PMCID:PMC4014769
  • Currier JM, Ishida MC, Gonzalez-Horta C, Sanchez-Ramirez B, Ballinas-Casarrubias L, Gutierrez-Torres DS, Ceron RH, Morales DV, Baeza Terrazas FA, Del Razo LM, Garcia-Vargas GG, Saunders RJ, Drobna Z, Fry RC, Matousek T, Buse JB, Mendez MA, Loomis D, Styblo M. 2014. Associations between arsenic species in exfoliated urothelial cells and prevalence of diabetes among residents of Chihuahua, Mexico. Environ Health Perspect 122(10):1088-1094. doi:10.1289/ehp.1307756 PMID:25000461 PMCID:PMC4181927
  • Gutierrez T, Aitken MD. 2014. Role of methylotrophs in the degradation of hydrocarbons during the Deepwater Horizon oil spill. ISME J 8(12):2543-2545. doi:10.1038/ismej.2014.88 PMID:24865772 PMCID:PMC4260708
  • Gutierrez T, Rhodes G, Mishamandani S, Berry D, Whitman WB, Nichols PD, Semple KT, Aitken MD. 2014. Polycyclic aromatic hydrocarbon degradation of phytoplankton-associated Arenibacter spp and description of Arenibacter algicola sp nov, an aromatic hydrocarbon-degrading bacterium. Appl Environ Microbiol 80(2):618-628. doi:10.1128/AEM.03104-13 PMID:24212584 PMCID:PMC3911095
  • Hu J, Adrion AC, Nakamura J, Shea D, Aitken MD. 2014. Bioavailability of (geno)toxic contaminants in polycyclic aromatic hydrocarbon-contaminated soil before and after biological treatment. Environ Eng Sci 31(4):176-182. doi:10.1089/ees.2013.0409 PMID:24803838 PMCID:PMC3993035
  • Johnston JE, Valentiner E, Maxson P, Miranda ML, Fry RC. 2014. Maternal cadmium levels during pregnancy associated with lower birth weight in infants in a North Carolina cohort. PLoS One 9(10):e109661. doi:10.1371/journal.pone.0109661 PMID:25285731 PMCID:PMC4186854
  • Jones MD, Rodgers-Vieira EA, Hu J, Aitken MD. 2014. Association of growth substrates and bacterial genera with benzo[a]pyrene mineralization in contaminated soil. Environ Eng Sci 31(12):689-697. doi:10.1089/ees.2014.0275 PMID:25469077 PMCID:PMC4245834
  • Lash LH, Chiu WA, Guyton KZ, Rusyn I. 2014. Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity. Mutat Res Rev Mutat Res 762:22-36. doi:10.1016/j.mrrev.2014.04.003 PMID:25484616 PMCID:PMC4254735
  • Lu SS, Sobus JR, Sallsten G, Albin M, Pleil JD, Gudmundsson A, Madden MC, Strandberg B, Wierzbicka A, Rappaport SM. 2014. Are urinary PAHs biomarkers of controlled exposure to diesel exhaust?. Biomarkers 19(4):332-339. doi:10.3109/1354750X.2014.910553 PMID:24754404 PMCID:PMC4737554
  • Mishamandani S, Gutierrez T, Aitken MD. 2014. DNA-based stable isotope probing coupled with cultivation methods implicates Methylophaga in hydrocarbon degradation. Front Microbiol 5:76. doi:10.3389/fmicb.2014.00076 PMID:24578702 PMCID:PMC3936186
  • Nakamura J, Mutlu E, Sharma V, Collins LB, Bodnar WM, Yu R, Lai Y, Moeller BC, Lu K, Swenberg JA. 2014. The endogenous exposome. DNA Repair (Amst) 19:3-13. doi:10.1016/j.dnarep.2014.03.031 PMID:24767943 PMCID:PMC4097170
  • Nye MD, Fry RC, Hoyo C, Murphy SK. 2014. Investigating epigenetic effects of prenatal exposure to toxic metals in newborns: Challenges and benefits. Med Epigenet 2:53-59. doi:10.1159/000362336 PMID:24955086 PMCID:PMC4061711
  • Pogribny IP, Rusyn I. 2014. Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma. Cancer Lett 342(2):223-230. doi:10.1016/j.canlet.2012.01.038 PMID:22306342 PMCID:PMC3971756
  • Pottenger LH, Andrews LS, Bachman AN, Boogaard PJ, Cadet J, Embry MR, Farmer PB, Himmelstein MW, Jarabek AM, Martin EA, Mauthe RJ, Persaud R, Preston J, Schoeny R, Skare J, Swenberg JA, Williams GM, Zeiger E, Zhang F, Kim JH. 2014. An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride. Crit Rev Toxicol 44(4):348-391. doi:10.3109/10408444.2013.873768 PMID:24494825
  • Rager JE, Moeller BC, Miller SK, Kracko D, Doyle-Eisele M, Swenberg JA, Fry RC. 2014. Formaldehyde-associated changes in microRNAs: tissue and temporal specificity in the rat nose, white blood cells, and bone marrow. Toxicol Sci 138(1):36-46. doi:10.1093/toxsci/kft267 PMID:24304932 PMCID:PMC3930361
  • Rager JE, Yosim A, Fry RC. 2014. Prenatal exposure to arsenic and cadmium impacts infectious disease-related genes within the glucocorticoid receptor signal transduction pathway. Int J Mol Sci 15(12):22374-22391. doi:10.3390/ijms151222374 PMID:25479081 PMCID:PMC4284714
  • Ray PD, Yosim A, Fry RC. 2014. Incorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challenges. Front Genet 5:201. doi:10.3389/fgene.2014.00201 PMID:25076963 PMCID:PMC4100550
  • Rusyn I, Chiu WA, Lash LH, Kromhout H, Hansen J, Guyton KZ. 2014. Trichloroethylene: mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard. Pharmacol Ther 141(1):55-68. doi:10.1016/j.pharmthera.2013.08.004 PMID:23973663 PMCID:PMC3867557
  • Sanders AP, Desrosiers TA, Warren JL, Herring AH, Enright D, Olshan A, Meyer RE, Fry RC. 2014. Association between arsenic, cadmium, manganese, and lead levels in private wells and birth defects prevalence in North Carolina: a semi-ecologic study. BMC Public Health 14:955. doi:10.1186/1471-2458-14-955 PMID:25224535 PMCID:PMC4190372
  • Sanders AP, Miller SK, Nguyen V, Kotch JB, Fry RC. 2014. Toxic metal levels in children residing in a smelting craft village in Vietnam: A pilot biomonitoring study. BMC Public Health 14:8. doi:10.1186/1471-2458-14-114 PMID:24495283 PMCID:PMC3922956
  • Sharma V, Collins LB, Clement JM, Zhang Z, Nakamura J, Swenberg JA. 2014. Molecular dosimetry of endogenous and exogenous O(6)-methyl-dG and N7-methyl-G adducts following low dose [D3]-methylnitrosourea exposures in cultured human cells. Chem Res Toxicol 27(4):480-482. doi:10.1021/tx5000602 PMID:24628573 PMCID:PMC3998766
  • Shibutani T, Ito S, Toda M, Kanao R, Collins LB, Shibata M, Urabe M, Koseki H, Masuda Y, Swenberg JA, Masutani C, Hanaoka F, Iwai S, Kuraoka I. 2014. Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication. Sci Rep 4:5220. doi:10.1038/srep05220 PMID:24910358 PMCID:PMC4048885
  • Sirenko O, Hesley J, Rusyn I, Cromwell EF. 2014. High-content high-throughput assays for characterizing the viability and morphology of human iPSC-derived neuronal cultures. Assay Drug Dev Technol 12(9-10):536-547. doi:10.1089/adt.2014.592 PMID:25506803 PMCID:PMC4270163
  • Smeester L, Yosim A, Nye MD, Hoyo C, Murphy SK, Fry RC. 2014. Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury. Genes (Basel) 5(2):477-496. doi:10.3390/genes5020477 PMID:24921406 PMCID:PMC4094944
  • Uehara T, Pogribny IP, Rusyn I. 2014. The DEN and CCl4 -induced mouse model of fibrosis and inflammation-associated hepatocellular carcinoma. Curr Protoc Pharmacol 66:14.30.1-14.3010. doi:10.1002/0471141755.ph1430s66 PMID:25181010 PMCID:PMC4214366
  • Wignall JA, Shapiro AJ, Wright FA, Woodruff TJ, Chiu WA, Guyton KZ, Rusyn I. 2014. Standardizing benchmark dose calculations to improve science-based decisions in human health assessments. Environ Health Perspect 122(5):499-505. doi:10.1289/ehp.1307539 PMID:24569956 PMCID:PMC4014768
  • Wright FA, Sullivan PF, Brooks AI, Zou F, Sun W, Xia K, Madar V, Jansen R, Chung W, Zhou Y, Abdellaoui A, Batista S, Butler C, Chen G, Chen T, D'Ambrosio D, Gallins P, Ha MJ, Hottenga JJ, Huang S, Kattenberg M, Kochar J, Middeldorp CM, Qu A, Shabalin AA, Tischfield JA, Todd L, Tzeng J, van Grootheest G, Vink JM, Wang Q, Wang W, Wang W, Willemsen G, Smit JH, de Geus EJ, Yin Z, Penninx BW, Boomsma DI. 2014. Heritability and genomics of gene expression in peripheral blood. Nat Genet 46(5):430-437. doi:10.1038/ng.2951 PMID:24728292 PMCID:PMC4012342
  • Ye W, Paul D, Gao L, Seckute J, Sangaiah R, Jayaraj K, Zhang Z, Kaminski P, Ealick SE, Gold A, Ball LM. 2014. Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites. PLoS One 9(12):e115082. doi:10.1371/journal.pone.0115082 PMID:25521390 PMCID:PMC4270796

2013

  • Ahir B, Sanders AP, Rager JE, Fry RC. 2013. Systems biology and birth defects prevention: Blockade of the glucocorticoid receptor prevents arsenic-induced birth defects. Environ Health Perspect 121(3):332-338. doi:10.1289/ehp.1205659 PMID:23458687 PMCID:PMC3616967
  • Dunlevy SR, Singleton D, Aitken MD. 2013. Biostimulation reveals functional redundancy of anthracene-degrading bacteria in polycyclic aromatic hydrocarbon-contaminated soil. Environ Eng Sci 30(11):697-705. doi:10.1089/ees.2013.0067 PMID:24302851 PMCID:PMC3833303
  • Edrissi B, Taghizadeh K, Moeller BC, Kracko D, Doyle-Eisele M, Swenberg JA, Dedon PC. 2013. Dosimetry of n(6)-formyllysine adducts following [(13)c(2)h2]-formaldehyde exposures in rats. Chem Res Toxicol 26(10):1421-1423. doi:10.1021/tx400320u PMID:24087891 PMCID:PMC3805309
  • Gray WG, Miller CT, Schrefler BA. 2013. Averaging theory for description of environmental problems: what have we learned?. Adv Water Resour 51:123-138. doi:10.1016/j.advwatres.2011.12.005 PMID:23393409 PMCID:PMC3563066
  • Gutierrez T, Berry D, Yang T, Mishamandani S, McKay L, Teske A, Aitken MD. 2013. Role of bacterial exopolysaccharides (EPS) in the fate of the oil released during the Deepwater Horizon Oil Spill. PLoS One 8(6):e67717. doi:10.1371/journal.pone.0067717 PMID:23826336 PMCID:PMC3694863
  • Gutierrez T, Green DH, Nichols PD, Whitman WB, Semple KT, Aitken MD. 2013. Polycyclovorans algicola gen nov, sp nov, an aromatic-hydrocarbon-degrading marine bacterium found associated with laboratory cultures of marine phytoplankton. Appl Environ Microbiol 79(1):205-214. doi:10.1128/AEM.02833-12 PMID:23087039 PMCID:PMC3536080
  • Gutierrez T, Singleton D, Berry D, Yang T, Aitken MD, Teske A. 2013. Hydrocarbon-degrading bacteria enriched by the Deepwater Horizon oil spill identified by cultivation and DNA-SIP. ISME J 7(11):2091-2104. doi:10.1038/ismej.2013.98 PMID:23788333 PMCID:PMC3806270
  • Hira A, Yabe H, Yoshida K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Nakamura J, Kojima S, Ogawa S, Matsuo K, Takata M, Yabe M. 2013. Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Blood 122(18):3206-3209. doi:10.1182/blood-2013-06-507962 PMID:24037726 PMCID:PMC3953058
  • Kushman ME, Kraft AD, Guyton KZ, Chiu WA, Makris SL, Rusyn I. 2013. A systematic approach for identifying, evaluating, and presenting mechanistic evidence in human health assessments. Regul Toxicol Pharmacol 67(2):266-277. doi:10.1016/j.yrtph.2013.08.005 PMID:23959061 PMCID:PMC3818152
  • LePrevost CE, Gray K, Hernandez-Pelletier M, Bouma B, Arellano C, Cope W. 2013. Need for improved risk communication of fish consumption advisories to protect maternal and child health: influence of primary informants. Int J Environ Res Public Health 10(5):1720-1734. doi:10.3390/ijerph10051720 PMID:23629591 PMCID:PMC3709344
  • Lonsdale J, Thomas J, Salvatore M, Phillips R, Lo E, Shad S, Hasz R, Walters G, Garcia F, Young N, Foster B, Moser M, Karasik E, Gillard B, Ramsey K, Sullivan S, Bridge J, Magazine H, Syron J, Fleming J, Siminoff L, Traino H, Mosavel M, Barker L, Jewell S, Rohrer D, Maxim D, Filkins D, Harbach P, Cortadillo E, Berghuis B, Turner L, Hudson E, Feenstra K, Sobin L, Robb J, Branton P, Korzeniewski G, Shive C, Tabor D, Qi L, Groch K, Nampally S, Buia S, Zimmerman A, Smith A, Burges R, Robinson K, Valentino K, Bradbury D, Cosentino M, Diaz-Mayoral N, Kennedy M, Engel T, Williams P, Erickson K, Ardlie K, Winckler W, Getz G, DeLuca D, MacArthur D, Kellis M, Thomson A, Young T, Gelfand E, Donovan M, Meng Y, Grant G, Mash D, Marcus Y, Basile M, Liu J, Zhu J, Tu Z, Cox NJ, Nicolae DL, Gamazon ER, Im HK, Konkashbaev A, Pritchard J, Stevens M, Flutre T, Wen X, Dermitzakis ET, Lappalainen T, Guigo R, Monlong J, Sammeth M, Koller D, Battle A, Mostafavi S, McCarthy M, Rivas M, Maller J, Rusyn I, Nobel AB, Wright FA, Shabalin AA, Feolo M, Sharopova N, Sturcke A, Paschal J, Anderson JM, Wilder EL, Derr LK, Green ED, Struewing JP, Temple G, Volpi S, Boyer JT, Thomson EJ, Guyer MS, Ng C, Abdallah A, Colantuoni D, Insel TR, Koester SE, Little A, Bender PK, Lehner T, Yao Y, Compton CC, Vaught JB, Sawyer S, Lockhart NC, Demchok J, Moore HF. 2013. The Genotype-Tissue Expression (GTEx) project. Nat Genet 45:580-585. doi:10.1038/ng.2653 PMID:23715323 PMCID:PMC4010069
  • Low Y, Sedykh A, Fourches D, Golbraikh A, Whelan M, Rusyn I, Tropsha A. 2013. Integrative chemical-biological read-across approach for chemical hazard classification. Chem Res Toxicol 26(8):1199-1208. doi:10.1021/tx400110f PMID:23848138 PMCID:PMC3818153
  • Moeller BC, Recio L, Green A, Sun W, Wright FA, Bodnar WM, Swenberg JA. 2013. Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure. Toxicol Sci 133(1):1-12. doi:10.1093/toxsci/kft029 PMID:23425604 PMCID:PMC3627555
  • Pachkowski BF, Nakamura J. 2013. A neutral glyoxal gel electrophoresis method for the detection and semi-quantitation of DNA single-strand breaks. Methods Mol Biol 1054:133-143. doi:10.1007/978-1-62703-565-1_8 PMID:23913289
  • Pogribny IP, Rusyn I. 2013. Environmental toxicants, epigenetics, and cancer. Advances in Experimental Medicine and Biology 754:215-232. doi:10.1007/978-1-4419-9967-2_11 PMID:22956504 PMCID:PMC4281087
  • Rager JE, Moeller BC, Doyle-Eisele M, Kracko D, Swenberg JA, Fry RC. 2013. Formaldehyde and epigenetic alterations: microRNA changes in the nasal epithelium of nonhuman primates. Environ Health Perspect 121(3):339-344. doi:10.1289/ehp.1205582 PMID:23322811 PMCID:PMC3621188
  • Reif DM, Sypa M, Lock EF, Wright FA, Wilson A, Cathey T, Judson RR, Rusyn I. 2013. ToxPi GUI: An interactive visualization tool for transparent integration of data from diverse sources of evidence. Bioinformatics 29(3):402-403. doi:10.1093/bioinformatics/bts686 PMID:23202747 PMCID:PMC3988461
  • Rusyn I, Lemon SM. 2013. Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?. Cancer Lett doi:10.1016/j.canlet.2013.06.028 PMID:23871966 PMCID:PMC3844040
  • Sanders AP, Smeester L, Rojas D, DeBussycher T, Wu MC, Wright FA, Zhou Y, Laine JE, Rager JE, Swamy GK, Ashley-Koch A, Miranda ML, Fry RC. 2013. Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. Epigenetics 9(2):29-38. doi:10.4161/epi.26798 PMID:24169490 PMCID:PMC3962531
  • Singleton D, Jones MD, Richardson SD, Aitken MD. 2013. Pyrosequence analyses of bacterial communities during simulated in situ bioremediation of polycyclic aromatic hydrocarbon-contaminated soil. Appl Microbiol Biotechnol 97(18):8381-8391. doi:10.1007/s00253-012-4531-0 PMID:23132343 PMCID:PMC3600395
  • Soldatow VY, LeCluyse EL, Griffith LG, Rusyn I. 2013. In vitro models for liver toxicity testing. Toxicol Res (Camb) 2:23-39. doi:10.1039/C2TX20051A PMID:23495363 PMCID:PMC3593300
  • Starr TB, Swenberg JA. 2013. A novel bottom-up approach to bounding low-dose human cancer risks from chemical exposures. Regul Toxicol Pharmacol 65(3):311-315. doi:10.1016/j.yrtph.2013.01.004 PMID:23352840
  • Swenberg JA, Moeller BC, Lu K, Rager JE, Fry RC, Starr TB. 2013. Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment. Toxicol Pathol 41(2):181-189. doi:10.1177/0192623312466459 PMID:23160431 PMCID:PMC3893912
  • Uehara T, Ainslie GR, Kutanzi K, Pogribny IP, Muskhelishvili L, Izawa T, Yamate J, Kosyk O, Shymoniak S, Bradford BU, Boorman GA, Bataller R, Rusyn I. 2013. Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis. Toxicol Sci 132(1):53-63. doi:10.1093/toxsci/kfs342 PMID:23288052 PMCID:PMC3576012
  • Uehara T, Kosyk O, Jeannot E, Bradford BU, Tech K, Macdonald JM, Boorman GA, Chatterjee S, Mason RP, Melnyk SB, Tryndyak VP, Pogribny IP, Rusyn I. 2013. Acetaminophen-induced acute liver injury in HCV transgenic mice. Toxicol Appl Pharmacol 266(2):224-232. doi:10.1016/j.taap.2012.11.019 PMID:23200774 PMCID:PMC3534780
  • Zeise L, Bois FY, Chiu WA, Hattis D, Rusyn I, Guyton KZ. 2013. Addressing human variability in next-generation human health risk assessments of environmental chemicals. Environ Health Perspect 121:23-31. doi:10.1289/ehp.1205687 PMID:23086705 PMCID:PMC3553440
  • Zhou Y, Barry WT, Wright FA. 2013. Empirical pathway analysis, without permutation. Biostatistics 14(3):573-585. doi:10.1093/biostatistics/kxt004 PMID:23428933 PMCID:PMC3677738
  • Zhou Y, Mayhew G, Sun Z, Xu X, Zou F, Wright FA. 2013. Space–time clustering and the permutation moments of quadratic forms. Stat 2(1):292-302. doi:10.1002/sta4.37 PMID:25210205 PMCID:PMC4157666

2012

  • Birak PS, Miller CT, Hauswirth SC, Rylander SC. 2012. Mobilization of manufactured gas plant tar with alkaline flushing solutions. Environ Sci Technol 46:426-433. doi:10.1021/es202278s PMID:22091957 PMCID:PMC3258375
  • Campbell J, Clewell RA, Gentry PR, Andersen ME, Clewell H. 2012. Physiologically based pharmacokinetic/toxicokinetic modeling. Chapter 18 in: Computational Toxicology: Methods in Molecular Biology. Humana Press, New York, NY. pp.439-499.
  • Guha N, Loomis D, Grosse Y, Secretan-Lauby B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Baan R, Mattock H, Straif K. 2012. Carcinogenicity of trichloroethylene, tetrachloroethylene, some other chlorinated solvents, and their metabolites. Lancet Oncol 13(12):1192-1193. doi:10.1016/S1470-2045(12)70485-0 PMID:23323277
  • Gutierrez T, Aitken MD, Nichols PD, Whitman WB. 2012. Porticoccus hydrocarbonoclasticus sp nov, an aromatic hydrocarbon-degrading bacterium identified in laboratory cultures of marine phytoplankton. Appl Environ Microbiol 78(3):628-637. doi:10.1128/AEM.06398-11 PMID:22139001 PMCID:PMC3264135
  • Hu J, Aitken MD. 2012. Desorption of polycyclic aromatic hydrocarbons from field-contaminated soil to a two-dimensional hydrophobic surface before and after bioremediation. Chemosphere 89:542-547. doi:10.1016/j.chemosphere.2012.05.046 PMID:22704210 PMCID:PMC3412927
  • Hu J, Nakamura J, Richardson SD, Aitken MD. 2012. Evaluating the effects of bioremediation on genotoxicity of polycyclic aromatic hydrocarbon-contaminated soil using genetically engineered, higher eukaryotic cell lines. Environ Sci Technol 46(8):4607-4613. doi:10.1021/es300020e PMID:22443351 PMCID:PMC3348858
  • Jackson AS, Rybak I, Helmig R, Gray WG, Miller CT. 2012. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 9. Transition region models. Adv Water Resour 42:71-90. doi:10.1016/j.advwatres.2012.01.006
  • Jeannot E, Boorman GA, Bradford BU, Shymoniak S, Tumurbaatar B, Weinman SA, Melnyk SB, Tryndyak VP, Pogribny IP, Rusyn I, Kosyk O. 2012. Increased incidence of aflatoxin B1-induced liver tumors in hepatitis virus C transgenic mice. Int J Cancer 130(6):1347-1356. doi:10.1002/ijc.26140 PMID:21500192 PMCID:PMC3161148
  • Jiang R, French JE, Stober V, Kang-Sickel JC, Zou F, Nylander-French LA. 2012. Single-nucleotide polymorphisms associated with skin naphthyl-keratin adduct levels in workers exposed to naphthalene. Environ Health Perspect 120:857-864. doi:10.1289/ehp.1104304 PMID:22391508 PMCID:PMC3385430
  • Lock EF, Abdo N, Huang R, Xia M, Kosyk O, O'Shea SH, Zhou Y, Sedykh A, Tropsha A, Austin CP, Tice RR, Wright FA, Rusyn I. 2012. Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model. Toxicol Sci 126(2):578-588. doi:10.1093/toxsci/kfs023 PMID:22268004 PMCID:PMC3307611
  • Lu K, Craft S, Nakamura J, Moeller BC, Swenberg JA. 2012. Use of LC-MS/MS and stable isotopes to differentiate hydroxymethyl and methyl DNA adducts from formaldehyde and nitrosodimethylamine. Chem Res Toxicol 25(3):664-675. doi:10.1021/tx200426b PMID:22148432 PMCID:PMC3307879
  • Lu K, Gul H, Upton PB, Moeller BC, Swenberg JA. 2012. Formation of hydroxymethyl DNA adducts in rats orally exposed to stable isotope labeled methanol. Toxicol Sci 126(1):28-38. doi:10.1093/toxsci/kfr328 PMID:22157354 PMCID:PMC3289495
  • Luke AM, Nakamura J. 2012. O-hydroxylamine-coupled alkaline gel electrophoresis assay for the detection and measurement of DNA single-strand breaks. Methods Mol Biol 920:307-313. doi:10.1007/978-1-61779-998-3_21 PMID:22941612 PMCID:PMC3664990
  • Messier KP, Akita Y, Serre ML. 2012. Integrating address geocoding, land use regression, and spatiotemporal geostatistical estimation for groundwater tetrachloroethylene. Environ Sci Technol 46(5):2772-2780. doi:10.1021/es203152a PMID:22264162 PMCID:PMC3494280
  • Mutlu E, Jeong Y, Collins LB, Ham AL, Upton PB, Hatch G, Winsett D, Evansky P, Swenberg JA. 2012. A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-oxoethyl)guanine in Sprague–Dawley rats. Chem Res Toxicol 25(2):391-399. doi:10.1021/tx200447w PMID:22211352 PMCID:PMC3288741
  • Nakamura J, Gul H, Tian X, Bultman SJ, Swenberg JA. 2012. Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system. PLoS One 7(3):e33563. doi:10.1371/journal.pone.0033563 PMID:22428069 PMCID:PMC3299801
  • Rager JE, Fry RC. 2012. The aryl hydrocarbon receptor pathway: a key component of the microRNA-mediated AML signalisome. Int J Environ Res Public Health 9:1939-1953. doi:10.3390/ijerph9051939 PMID:22754483 PMCID:PMC3386597
  • Richardson SD, Jones MD, Singleton D, Aitken MD. 2012. Long-term simulation of in situ biostimulation of polycyclic aromatic hydrocarbon-contaminated soil. Biodegradation 23:621-633. doi:10.1007/s10532-012-9538-9 PMID:22311590 PMCID:PMC4752832
  • Sanders AP, Flood K, Chiang S, Herring AH, Wolf L, Fry RC. 2012. Towards prenatal biomonitoring in North Carolina: assessing arsenic, cadmium, mercury, and lead levels in pregnant women. PLoS One 7(3):e31354. doi:10.1371/journal.pone.0031354 PMID:22427803 PMCID:PMC3302877
  • Singleton D, Hu J, Aitken MD. 2012. Heterologous expression of polycyclic aromatic hydrocarbon ring-hydroxylating dioxygenase genes from a novel pyrene-degrading betaproteobacterium. Appl Environ Microbiol 78(10):3552-3559. doi:10.1128/AEM.00173-12 PMID:22427500 PMCID:PMC3346350
  • Wright FA, Shabalin AA, Rusyn I. 2012. Computational tools for discovery and interpretation of expression quantitative trait loci. Pharmacogenomics 13(3):343-352. doi:10.2217/pgs.11.185 PMID:22304583 PMCID:PMC3295835

2011

  • Adami H, Berry CL, Breckenridge CB, Smith LL, Swenberg JA, Trichopoulos D, Weiss NS, Pastoor TP. 2011. Toxicology and epidemiology: improving the science with a framework for combining toxicological and epidemiological evidence to establish causal inference. Toxicol Sci 122(2):223-234. doi:10.1093/toxsci/kfr113 PMID:21561883 PMCID:PMC3155086
  • Birak PS, Newman AP, Richardson SD, Hauswirth SC, Pedit JA, Aitken MD, Miller CT. 2011. Cosolvent flushing for the remediation of PAHs from former manufactured gas plants. J Contam Hydrol 126(1-2):72-84. doi:10.1016/j.jconhyd.2011.07.005 PMID:21871689 PMCID:PMC3200444
  • Bradford BU, Lock EF, Kosyk O, Kim S, Uehara T, Harbourt D, DeSimone MC, Threadgill DW, Tryndyak VP, Pogribny IP, Bleyle L, Koop DR, Rusyn I. 2011. Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicol Sci 120(1):206-217. doi:10.1093/toxsci/kfq362 PMID:21135412 PMCID:PMC3044200
  • Gatti DM, Lu L, Williams RW, Sun W, Wright FA, Threadgill DW, Rusyn I. 2011. MicroRNA expression in the livers of inbred mice. Mutat Res 714:126-133. doi:10.1016/j.mrfmmm.2011.05.007 PMID:21616085 PMCID:PMC3166582
  • Gray WG, Miller CT. 2011. TCAT analysis of capillary pressure in non-equilibrium, two-fluid-phase, porous medium systems. Adv Water Resour 34:770-778. doi:10.1016/j.advwatres.2011.04.001 PMID:21603082 PMCID:PMC3097477
  • Grosse Y, Baan R, Secretan-Lauby B, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Islami F, Galichet L, Straif K. 2011. Carcinogenicity of chemicals in industrial and consumer products, food contaminants and flavourings, and water chlorination byproducts. Lancet Oncol 12(4):328-329. doi:10.1016/S1470-2045(11)70088-2 PMID:21598447
  • Gutierrez T, Singleton D, Aitken MD, Semple KT. 2011. Stable isotope probing of an algal bloom to identify uncultivated members of the Rhodobacteraceae associated with low-molecular-weight polycyclic aromatic hydrocarbon degradation. Appl Environ Microbiol 77(21):7856-7860. doi:10.1128/AEM.06200-11 PMID:21926219 PMCID:PMC3209190
  • Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y. 2011. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333(6047):1300-1303. doi:10.1126/science.1210597 PMID:21778364 PMCID:PMC3495246
  • Jeannot E, Pogribny IP, Beland FA, Rusyn I. 2011. Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells. Cancer Lett 301:161-167. doi:10.1016/j.canlet.2010.11.010 PMID:21168264 PMCID:PMC3035933
  • Jones MD, Crandell DW, Singleton D, Aitken MD. 2011. Stable-isotope probing of the polycyclic aromatic hydrocarbon-degrading bacterial guild in a contaminated soil. Environ Microbiol 13(10):2623-2632. doi:10.1111/j.1462-2920.2011.02501.x PMID:21564459 PMCID:PMC4755288
  • Jones MD, Singleton D, Sun W, Aitken MD. 2011. Multiple DNA extractions coupled with stable-isotope probing of anthracene-degrading bacteria in contaminated soil. Appl Environ Microbiol 77(9):2984-2991. doi:10.1128/AEM.01942-10 PMID:21398486 PMCID:PMC3126383
  • Jung D, Matson CW, Collins LB, Laban G, Stapleton HM, Bickham JW, Swenberg JA, Di Giulio RT. 2011. Genotoxicity in Atlantic killifish (Fundulus heteroclitus) from a PAH-contaminated Superfund site on the Elizabeth River, Virginia. Ecotoxicology 20:1890-1899. doi:10.1007/s10646-011-0727-9 PMID:21706406 PMCID:PMC3203518
  • Kang-Sickel JC, Butler MA, Frame L, Serdar B, Chao YE, Egeghy PP, Rappaport SM, Toennis CA, Li W, Borisova T, French JE, Nylander-French LA. 2011. The utility of naphthyl-keratin adducts as biomarkers for jet-fuel exposure. Biomarkers 16:590-599. doi:10.3109/1354750x.2011.611598 PMID:21961652 PMCID:PMC4174274
  • Koturbash I, Scherhag A, Sexton K, Bodnar WM, Tryndyak VP, Swenberg JA, Beland FA, Pogribny IP, Rusyn I, Latendresse JR. 2011. Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-Butadiene. Environ Health Perspect 119:635-640. doi:10.1289/ehp.1002910 PMID:21147608 PMCID:PMC3094413
  • Lu K, Moeller BC, Doyle-Eisele M, McDonald JD, Swenberg JA. 2011. Molecular dosimetry of N2-hydroxymethyl-dG DNA adducts in rats exposed to formaldehyde. Chem Res Toxicol 24(2):159-161. doi:10.1021/tx1003886 PMID:21155545 PMCID:PMC3128468
  • Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. 2011. Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. Mutat Res 694:65-71. doi:10.1016/j.mrfmmm.2010.08.008 PMID:20851134 PMCID:PMC2992575
  • McHale CM, Zhang L, Lan Q, Vermeulen R, Li G, Hubbard AE, Porter KE, Thomas R, Portier CJ, Shen M, Rappaport SM, Yin S, Rothman N, Smith MT. 2011. Global gene expression profiling of a population exposed to a range of benzene levels. Environ Health Perspect 119:628-634. doi:10.1289/ehp.1002546 PMID:21147609 PMCID:PMC3094412
  • Moeller BC, Lu K, Doyle-Eisele M, McDonald JD, Gigliotti A, Swenberg JA. 2011. Determination of N2-hydroxymethyl-dG adducts in the nasal epithelium and bone marrow of nonhuman primates following 13CD2-formaldehyde inhalation exposure. Chem Res Toxicol 24(2):162-164. doi:10.1021/tx1004166 PMID:21222454 PMCID:PMC3273041
  • Money ES, Sackett DK, Aday DD, Serre ML. 2011. Using river distance and existing hydrography data can improve the geostatistical estimation of fish tissue mercury at unsampled locations. Environ Sci Technol 45(18):7746-7753. doi:10.1021/es2003827 PMID:21842901
  • Richardson SD, Aitken MD. 2011. Desorption and bioavailability of polycyclic aromatic hydrocarbons in contaminated soil subjected to long-term in situ biostimulation. Environ Toxicol Chem 30:2674-2681. doi:10.1002/etc.682 PMID:21932296 PMCID:PMC3215808
  • Richardson SD, Lebron BL, Miller CT, Aitken MD. 2011. Recovery of phenanthrene-degrading bacteria after simulated in situ persulfate oxidation in contaminated soil. Environ Sci Technol 45(2):719-725. doi:10.1021/es102420r PMID:21162560 PMCID:PMC3021091
  • Ridpath JR, Takeda S, Swenberg JA, Nakamura J. 2011. Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action. Environ Mol Mutagen 52(2):153-160. doi:10.1002/em.20595 PMID:20839229 PMCID:PMC3280086
  • Sanders AP, Messier KP, Shehee M, Rudo K, Serre ML, Fry RC. 2011. Arsenic in North Carolina: public health implications. Environ Int 38:10-16. doi:10.1016/j.envint.2011.08.005 PMID:21982028 PMCID:PMC3539775
  • Sedykh A, Zhu H, Tang H, Zhang L, Richard A, Rusyn I, Tropsha A. 2011. Use of in vitro HTS-derived concentration-response data as biological descriptors improves the accuracy of QSAR models of in vivo toxicity. Environ Health Perspect 119(3):364-370. doi:10.1289/ehp.1002476 PMID:20980217 PMCID:PMC3060000
  • Singleton D, Richardson SD, Aitken MD. 2011. Pyrosequence analysis of bacterial communities in aerobic bioreactors treating polycyclic aromatic hydrocarbon-contaminated soil. Biodegradation 22:1061-1073. doi:10.1007/s10532-011-9463-3 PMID:21369833 PMCID:PMC3227512
  • Swenberg JA, Lu K, Moeller BC, Gao L, Upton PB, Nakamura J, Starr TB. 2011. Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment. Toxicol Sci 120(suppl1):S130-S145. doi:10.1093/toxsci/kfq371 PMID:21163908 PMCID:PMC3043087
  • Tan Y, Clewell H, Campbell J, Andersen ME. 2011. Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment. Int J Environ Res Public Health 8(5):1613-1630. doi:10.3390/ijerph8051613 PMID:21655141 PMCID:PMC3108131
  • Wu K, Chiang S, Shih W, Huang CJ, Chen M, Swenberg JA. 2011. The application of mass spectrometry in molecular dosimetry: Ethylene oxide as an example. Mass Spectrom Rev 30(5):733-756. doi:10.1002/mas.20299 PMID:21328599
  • Zhang L, Lan Q, Guo W, Hubbard AE, Li G, Rappaport SM, McHale CM, Shen M, Vermeulen R, Yin S, Rothman N, Smith MT, Ji Z. 2011. Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. Carcinogenesis 32:605-612. doi:10.1093/carcin/bgq286 PMID:21216845 PMCID:PMC3066415
  • Zhang Z, Sangaiah R, Gold A, Ball LM. 2011. Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons. Org Biomol Chem 9:5431-5435. doi:10.1039/C0OB01107J PMID:21670806

2010

  • Anderson DM, McLaughlin RM, Miller CT. 2010. A sharp-interface interpretation of a continuous density model for homogenization of gravity-driven flow in porous media. Physica D 239(19):1855-1866. doi:10.1016/j.physd.2010.06.009
  • Asagoshi K, Tano K, Chastain PD, Adachi N, Sonoda E, Kikuchi K, Koyama H, Nagata K, Kaufman DG, Takeda S, Wilson SH, Watanabe M, Swenberg JA, Nakamura J. 2010. FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells. Mol Cancer Res 8(2):204-215. doi:10.1158/1541-7786.MCR-09-0253 PMID:20145043 PMCID:PMC2824787
  • Boysen G, Collins LB, Liao S, Luke AM, Pachkowski BF, Watters JL, Swenberg JA. 2010. Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine by ultra high pressure liquid chromatography–heat assisted electrospray ionization–tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 878(3-4):375-380. doi:10.1016/j.jchromb.2009.12.004 PMID:20022307 PMCID:PMC5085061
  • Bu S, Huang J, Boyer TH, Miller CT. 2010. An evaluation of solution algorithms and numerical approximation methods for modeling an ion exchange process. J Comput Phys 229(13):4996-5010. doi:10.1016/j.jcp.2010.03.021 PMID:20577570 PMCID:PMC2888111
  • Chastain PD, Nakamura J, Rao S, Chu H, Ibrahim J, Swenberg JA, Kaufman DG. 2010. Abasic sites preferentially form at regions undergoing DNA replication. FASEB J 24(10):3674-80. doi:10.1096/fj.09-145276 PMID:20511393 PMCID:PMC2996904
  • Cowerd RB, Asmar MM, Alderman JM, Alderman EA, Garland AL, Busby WH, Bodnar WM, Rusyn I, Medoff BD, Tisch R, Swenberg JA, Zeisel S, Combs TP, Mayer-Davis E. 2010. Adiponectin lowers glucose production by increasing SOGA. Am J Pathol 177(4):1936-1945. doi:10.2353/ajpath.2010.100363 PMID:20813965 PMCID:PMC2947288
  • De Nazelle A, Arunachalam S, Serre ML. 2010. Bayesian maximum entropy integration of ozone observations and model predictions: an application for attainment demonstration in North Carolina. Environ Sci Technol 44:5707-5713. doi:10.1021/es100228w PMID:20590110 PMCID:PMC2912419
  • Gatti DM, Zhao N, Chesler EJ, Bradford BU, Shabalin AA, Yordanova R, Lu L, Rusyn I. 2010. Sex-specific gene expression in the BXD mouse liver. Physiol Genomics 42(3):456-468. doi:10.1152/physiolgenomics.00110.2009 PMID:20551147 PMCID:PMC2929887
  • Gray WG, Miller CT. 2010. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 8. Interface and common curve dynamics. Adv Water Resour 33:1427-1443. doi:10.1016/j.advwatres.2010.07.002 PMID:21197134 PMCID:PMC3010759
  • Kang-Sickel JC, Stober V, French JE, Nylander-French LA. 2010. Exposure to naphthalene induces naphthyl-keratin adducts in human epidermis in vitro and in vivo. Biomarkers 15:488-497. doi:10.3109/1354750x.2010.485700 PMID:20500019 PMCID:PMC2923669
  • Lu K, Collins LB, Ru H, Bermudez E, Swenberg JA. 2010. Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not Leukemia. Toxicol Sci 116(2):441-451. doi:10.1093/toxsci/kfq061 PMID:20176625 PMCID:PMC2905397
  • Lu K, Ye W, Zhou L, Collins LB, Chen X, Gold A, Ball LM, Swenberg JA. 2010. Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers. J Am Chem Soc 132(10):3388-3399. doi:10.1021/ja908282f PMID:20178313 PMCID:PMC2866014
  • McClure JE, Gray WG, Miller CT. 2010. Beyond anisotropy: examining non-Darcy flow in asymmetric porous media. Transp Porous Media 84(2):535-548. doi:10.1007/s11242-009-9518-7
  • Mutlu E, Collins LB, Stout MD, Upton PB, Daye LR, Winsett D, Hatch G, Evansky P, Swenberg JA. 2010. Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N2,3-ethenoguanine in tissues of adult and weanling rats following exposure to [13C2]-VC. Chem Res Toxicol 23(9):1485-1491. doi:10.1021/tx1001767 PMID:20799743 PMCID:PMC3104734
  • Rusyn I, Gatti DM, Wilshire T, Kleeberger SR, Threadgill DW. 2010. Toxicogenetics: Population-based testing of drug and chemical safety in mouse models. Pharmacogenomics 11(8):1127-1136. doi:10.2217/pgs.10.100 PMID:20704464 PMCID:PMC3035927
  • Sun W, Wright FA. 2010. A geometric interpretation of the permutation p-value and its application in EQTL studies. Annals of Applied Statistics 4:1014-1033. doi:10.1214/09-aoas298
  • Wright D, Gasda S, Farthing MW, Murphy L, Knight S, Brubaker G, Miller CT. 2010. Dense, viscous brine behavior in heterogeneous porous medium systems. J Contam Hydrol 115:46-63. doi:10.1016/j.jconhyd.2010.03.005 PMID:20444520 PMCID:PMC2884067
  • Zhu H, Aitken MD. 2010. Surfactant-enhanced desorption and biodegradation of polycyclic aromatic hydrocarbons in contaminated soil. Environ Sci Technol 44:7260-7265. doi:10.1021/es100112a PMID:20586488 PMCID:PMC2947565
  • Zhu H, Singleton D, Aitken MD. 2010. Effects of nonionic surfactant addition on populations of polycyclic aromatic hydrocarbon-degrading bacteria in a bioreactor treating contaminated soil. Environ Sci Technol 44:7266-7271. doi:10.1021/es100114g PMID:20707373 PMCID:PMC2947603

2009

  • Birak PS, Miller CT. 2009. Dense non-aqueous phase liquids at former manufactured gas plants: challenges to modeling and remediation. J Contam Hydrol 105(3-4):81-98. doi:10.1016/j.jconhyd.2008.12.001 PMID:19176266 PMCID:PMC2742311
  • Bordeerat NK, Georgieva NI, Klapper DG, Collins LB, Cross TJ, Borchers CH, Swenberg JA, Boysen G. 2009. Accurate quantitation of standard peptides used for quantitative proteomics. Proteomics 9(15):3939-3944. doi:10.1002/pmic.200900043 PMID:19637239 PMCID:PMC2766299
  • Boysen G, Pachkowski BF, Nakamura J, Swenberg JA. 2009. The formation and biological significance of N7-guanine adducts. Mutat Res 678(2):76-94. doi:10.1016/j.mrgentox.2009.05.006 PMID:19465146 PMCID:PMC2739241
  • DeSimone MC, Harbourt D, Boysen G, Collins LB, Waldyanatha S, Bradford BU, Threadgill DW, Rusyn I, Kim S. 2009. Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I. 2009. Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mamm Genome 20(7):437-446. doi:10.1007/s00335-009-9199-0 PMID:19609828 PMCID:PMC2745627
  • Gatti DM, Shabalin AA, Lam T, Wright FA, Rusyn I, Nobel AB. 2009. FastMap: fast eQTL mapping in homozygous populations. Bioinformatics 25(4):482-489. doi:10.1093/bioinformatics/btn648 PMID:19091771 PMCID:PMC2642639
  • Gatti DM, Sypa M, Rusyn I, Wright FA, Barry WT. 2009. SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy. Bioinformatics 25(4):541-542. doi:10.1093/bioinformatics/btn655 PMID:19098030 PMCID:PMC2642635
  • Gray WG, Miller CT. 2009. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 5. single-fluid-phase transport. Adv Water Resour 32(5):681-711. doi:10.1016/j.advwatres.2008.10.013 PMID:22563137 PMCID:PMC3342734
  • Hege A, Ross PK, Threadgill DW, Rusyn I. 2009. Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • Jackson AS, Miller CT, Gray WG. 2009. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 6. Two-fluid-phase flow. Adv Water Resour 32(6):779-795. doi:10.1016/j.advwatres.2008.11.010
  • Kim D, Nylander-French LA. 2009. Physiologically-Based Toxicokinetic Models and Their Application in Human Exposure and Internal Dose Assessment. In: Molecular, Clinical and Environmental Toxicology Volume 1. pp.470.
  • Kim S, Boysen G, Swenberg JA, Gold A, Ball LM, Bradford BU, Rusyn I, Collins LB. 2009. Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicology 262(3):230-238. doi:10.1016/j.tox.2009.06.013 PMID:19549554 PMCID:PMC2765814
  • Kim S, Kim D, Pollack GM, Collins LB, Rusyn I. 2009. Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicol Appl Pharmacol 238(1):90-99. doi:10.1016/j.taap.2009.04.019 PMID:19409406 PMCID:PMC2737827
  • Lan Q, Zhang L, Shen M, Jo WJ, Vermeulen R, Li G, Vulpe CD, Lim S, Ren X, Rappaport SM, Berndt SI, Yeager M, Yuenger J, Hayes RB, Linet MS, Yin S, Chanock SJ, Smith MT, Rothman N. 2009. Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity. Carcinogenesis 30(1):50-58. doi:10.1093/carcin/bgn249 PMID:18978339 PMCID:PMC2639030
  • Martinez S, Bradford BU, Kosyk O, Kaiser R, Soldatow VY, Stewart T, Amaral K, Black C, Ferguson S, LeCluyse EL, Rusyn I. 2009. Development of the in vitro toxicogenetic model for hepatotoxicity. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • McHale CM, Zhang L, Lan Q, Li G, Hubbard AE, Forrest MS, Vermeulen R, Chen J, Shen M, Rappaport SM, Yin S, Smith MT, Rothman N. 2009. Changes in the peripheral blood transcriptome associated with occupational benzene exposure identified by cross-comparison on two microarray platforms. Genomics 93(4):343-349. doi:10.1016/j.ygeno.2008.12.006 PMID:19162166 PMCID:PMC2693268
  • Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J. 2009. Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS. Mutat Res 671(1-2):93-99. doi:10.1016/j.mrfmmm.2009.09.006 PMID:19778542 PMCID:PMC2784157
  • Rappaport SM, Kim S, Lan Q, Vermeulen R, Waidyanatha S, Zhang L, Li G, Yin S, Hayes RB, Rothman N, Smith MT. 2009. Evidence that humans metabolize benzene via two pathways. Environ Health Perspect 117:946-952. doi:10.1289/ehp.0800510 PMID:19590688 PMCID:PMC2702411
  • Romanov S, Gatti DM, Tsuchlya M, Zeng M, Medvedev A, Rusyn I. 2009. Profiling of multiple transcription factors activity in mouse liver. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • Ross PK, Woods CG, Bradford BU, Kosyk O, Gatti DM, Cunningham ML, Rusyn I. 2009. Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver. Toxicol Appl Pharmacol 235(2):199-207. doi:10.1016/j.taap.2008.12.011 PMID:19136022 PMCID:PMC2654411
  • Singleton D, Guzman Ramirez L, Aitken MD. 2009. Characterization of a polycyclic aromatic hydrocarbon degradation gene cluster in a phenanthrene-degrading Acidovorax strain. Appl Environ Microbiol 75(9):2613-2620. doi:10.1128/AEM.01955-08 PMID:19270134 PMCID:PMC2681696
  • Sobus JR, Waidyanatha S, McClean MD, Herrick RF, Smith TJ, Garshick E, Laden F, Hart JE, Zheng Y, Rappaport SM. 2009. Urinary naphthalene and phenanthrene as biomarkers of occupational exposure to polycyclic aromatic hydrocarbons. Occup Environ Med 66(2):99-104. doi:10.1136/oem.2008.041418 PMID:19017700 PMCID:PMC2633650
  • Swenberg JA, Starr TB, Albertini R, Walker V. 2009. Response to Keshava et al. Chem Res Toxicol 22(1):10-12. doi:10.1021/tx800438g
  • Ye W, Gold A, Ball LM, Swenberg JA, Lu K. 2009. Formation of S-[1-(N2-deoxyguanosinyl)methyl]glutathione between glutathione and DNA induced by formaldehyde. J Am Chem Soc 131(10):3414-3415. doi:10.1021/ja808048c PMID:19239220 PMCID:PMC3277947
  • Zhao N, Gatti DM, Rusyn I. 2009. Genome-level analysis of genetic regulation of sex-specific gene expression In mouse liver. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • Zhu H, Martin T, Ye L, Sedykh A, Young D, Tropsha A. 2009. Quantitative structure-activity relationship modeling of rat acute toxicity by oral exposure. Chem Res Toxicol 22(12):1913-1921. doi:10.1021/tx900189p PMID:19845371 PMCID:PMC2796713
  • Zhu H, Ye L, Richard A, Golbraikh A, Wright FA, Rusyn I, Tropsha A. 2009. A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents. Environ Health Perspect 117(8):1257-64. PMID:19672406

2008

  • Boyer TH, Miller CT, Singer PC. 2008. Modeling the removal of dissolved organic carbon by ion exchange in a completely mixed flow reactor. Water Res 42(8-9):1897-1906. doi:10.1016/j.watres.2007.11.018 PMID:18082241
  • Brusick D, Small MS, Cavalieri EL, Chakravarti D, Ding X, Longfellow DG, Nakamura J, Rogan EC, Swenberg JA. 2008. Possible genotoxic modes of action for naphthalene. Regul Toxicol Pharmacol 51(2Suppl):S43-S50. doi:10.1016/j.yrtph.2007.12.002 PMID:18194829
  • Chao YE, Zhao Y, Kupper LL, Nylander-French LA. 2008. Quantifying the relative importance of predictors in multiple linear regression analyses for public health studies. J Occup Environ Hyg 5(8):519-529. doi:10.1080/15459620802225481 PMID:18569519
  • Fowler KR, Reese JP, Kees CE, Dennis JE, Kelley CT, Miller CT, Audet C, Booker AJ, Couture G, Darwin RW, Farthing MW, Finkel DE, Gablonsky JM, Gray G, Kolda TG. 2008. A comparison of derivative-free optimization methods for groundwater supply and hydraulic capture community problems. Adv Water Resour 31(5):743-757. doi:10.1016/j.advwatres.2008.01.010
  • Gatti DM, Shabalin AA, Rusyn I, Wright FA, Nobel AB. 2008. Fast association mapping using summation trees. In: 7th Annual Meeting of the Complex Traits Consortium,. Montreal, Canada.
  • Han J, Danell RM, Patel JR, Gumerov DR, Scarlett CO, Speir J, Parker C, Rusyn I, Zeisel S, Borchers CH. 2008. Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry. Metabolomics 4(2):128-140. doi:10.1007/s11306-008-0104-8 PMID:19081807 PMCID:PMC2600444
  • Jeong Y, Walker NJ, Burgin DE, Kissling G, Gupta M, Kupper LL, Birnbaum LS, Swenberg JA. 2008. Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons. Free Radic Biol Med 45(5):585-591. doi:10.1016/j.freeradbiomed.2008.04.043 PMID:18534201 PMCID:PMC2570591
  • Jones MD, Singleton D, Carstensen D, Powell SN, Swanson JS, Pfaender FK, Aitken MD. 2008. Effect of incubation conditions on the enrichment of pyrene-degrading bacteria identified by stable-isotope probing in an aged, PAH-contaminated soil. Microb Ecol 56(2):341-349. doi:10.1007/s00248-007-9352-9 PMID:18165874
  • Kang-Sickel JC, Nam T, Jayaraj K, Ball LM, French JE, Klapper DG, Gold A, Nylander-French LA. 2008. S-arylcysteine-keratin adducts as biomarkers of human dermal exposure to aromatic hydrocarbons. Chem Res Toxicol 21(4):852-858. doi:10.1021/tx7003773 PMID:18361511
  • Kim D, Farthing MW, Miller CT, Nylander-French LA. 2008. Mathematical description of the uptake of hydrocarbons in jet fuel into the stratum corneum of human volunteers. Toxicol Lett 178(3):146-151. doi:10.1016/j.toxlet.2008.03.005 PMID:18423910 PMCID:PMC2443700
  • Kim S, Collins LB, Pollack GM, Rusyn I. 2008. Pharmacokinetic modeling of trichloroethylene metabolism in B6C3F1 mice: Formation and disposition of trichloroacetic add, dichloroacetic add, S-(1,2-dichlorovinyl)glutathlone and S-(1,2-dichlorovlnyl)-L-cystelne. In: NIEHS Superfund Basic Research & Training Program 2008 Annual Meeting. Pacific Grove, CA.
  • Lu K, Boysen G, Swenberg JA, Gao L, Collins LB. 2008. Formaldehyde-induced histone modifications in vitro. Chem Res Toxicol 21(8):1586-1593. doi:10.1021/tx8000576 PMID:18656964
  • Miller CT, Gray WG. 2008. Hydrogeological research, education, and practice: a path to future contributions. Journal of Hydrologic Engineering 13(1):7-12.
  • Miller CT, Gray WG. 2008. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 4. Species transport fundamentals. Adv Water Resour 31(3):577-597. doi:10.1016/j.advwatres.2007.11.004 PMID:19255613 PMCID:PMC2587001
  • Park J, Ball LM, Richardson SD, Zhu H, Aitken MD. 2008. Oxidative mutagenicity of polar fractions from polycyclic aromatic hydrocarbon-contaminated soils. Environ Toxicol Chem 27(11):2207-2215. doi:10.1897/07-572.1 PMID:18517307
  • Pogribny IP, Rusyn I, Beland FA. 2008. Epigenetic aspects of genotoxic and non-genotoxic hepatocarcinogenesis: studies in rodents. Environ Mol Mutagen 49(1):9-15. doi:10.1002/em.20342 PMID:17879298 PMCID:PMC2705440
  • Pogribny IP, Tryndyak VP, Boureiko A, Melnyk SB, Bagnyukova TV, Montgomery B, Rusyn I. 2008. Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver. Mutat Res 644(1-2):17-23. doi:10.1016/j.mrfmmm.2008.06.009 PMID:18639561 PMCID:PMC2571982
  • Powell SN, Singleton D, Aitken MD. 2008. Effects of enrichment with salicylate on bacterial selection and PAH mineralization in a microbial community from a bioreactor treating contaminated soil. Environ Sci Technol 42(11):4099-4105. PMID:18589972
  • Rusyn I, Harrill AH. 2008. Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity. Expert Opin Drug Metab Toxicol 4(11):1379-1389. doi:10.1517/17425255.4.11.1379 PMID:18950280
  • Seyedabbasi MA, Farthing MW, Imhoff PT, Miller CT. 2008. The influence of wettability on NAPL dissolution fingering. Adv Water Resour 31:1687-1696. doi:10.1016/j.advwatres.2008.08.003
  • Singleton D, Richardson SD, Aitken MD. 2008. Effects of enrichment with phthalate on polycyclic aromatic hydrocarbon biodegradation in contaminated soil. Biodegradation 19(4):577-587. PMID:17990065
  • Sobus JR, Pleil JD, Madden CM, Funk WE, Hubbard HE, Rappaport SM. 2008. Identification of surrogate measures of diesel exhaust exposure in chamber study with human subjects. Environ Sci Technol 42:8822-8828. doi:10.1021/es800813v PMID:19192804
  • Swenberg JA, Fryar-Tita E, Jeong Y, Boysen G, Starr TB, Walker V, Albertini R. 2008. Biomarkers in toxicology and risk assessment: informing critical dose-response relationships. Chem Res Toxicol 21(1):253-265. doi:10.1021/tx700408t PMID:18161944
  • Waldyanatha S, Rappaport SM. 2008. Hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoqulnone and 1,4-naphthoquinone in Swiss Webster mice. Chem Biol Interact 172:105-114. PMID:18291356
  • Zhu H, Roper JC, Pfaender FK, Aitken MD. 2008. Effects of anaerobic incubation on the desorption of polycyclic aromatic hydrocarbons from contaminated soils. Environ Toxicol Chem 27(4):837-844. doi:10.1897/07-166.1 PMID:18333673
  • Zhu H, Rusyn I, Richard A, Tropsha A. 2008. Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity. Environ Health Perspect 116(4):506-13. PMID:18414635

2007

  • Carter G, Serre ML, Akita Y. 2007. Spatiotemporal nonattainment assessment of surface water tetrachloroethylene in New Jersey. J Environ Qual 36(2):508-520. PMID:17332255
  • Gray WG, Miller CT. 2007. Consistent thermodynamic formulations for multiscale hydrologic systems: fluid pressures. Water Resour Res 43:
  • Kim D, Andersen ME, Chao YE, Egeghy PP, Rappaport SM, Nylander-French LA. 2007. PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthalene. Environ Health Perspect 115(6):894-901. doi:10.1289/ehp.9778 PMID:17589597 PMCID:PMC1892111
  • Kim D, Andersen ME, Chao YE, Egeghy PP, Rappaport SM, Nylander-French LA. 2007. Prediction of human dermal and inhalation exposures to jet fuel by analysis of a PBTK model. Environ Health Perspect 115(6):894-901.
  • Kim S, Lan Q, Waidyanatha S, Chanock SJ, Johnson BA, Vermeulen R, Smith MT, Zhang L, Li G, Shen M, Yin S, Rothman N, Rappaport SM. 2007. Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations. Pharmacogenet Genomics 17(10):789-801. PMID:17885617
  • Kupper LL, Swenberg JA, Waiters JL, Satia JA, Schroeder JC. 2007. Associations of antioxidant nutrients and oxidative DNA damage in healthy African-American and White adults. Cancer Epidemiol Biomarkers Prev 16(7):1428-1436. doi:10.1158/1055-9965.EPI-06-1030 PMID:17627008
  • Li H, Farthing MW, Dawson CN, Miller CT. 2007. Local discontinuous galerkin approximations of Richards' Equation. Adv Water Resour 30(3):555-575.
  • Li H, Farthing MW, Miller CT. 2007. Adaptive local discontinuous Galerkin approximation to Richards' equation. Adv Water Resour 30(9):1883-1901.
  • Lin Y, Vermeulen R, Tsai CH, Waidyanatha S, Lan Q, Rothman N, Smith MT, Zhang L, Shen M, Li G, Yin S, Kim S, Rappaport SM. 2007. Albumin adducts of electrophilic benzene metabolites in benzene-exposed and control workers. Environ Health Perspect 115(1):28-34. PMID:17366815
  • McClure JE, Adalsteinsson D, Pan C, Gray WG, Miller CT. 2007. Approximation of interfacial properties in multiphase porous medium systems. Adv Water Resour 30(3):354-365.
  • Pan C, Dalla E, Franzosi D, Miller CT. 2007. Pore-scale simulation of entrapped non-aqueous phase liquid dissolution. Adv Water Resour 30(3):623-640.
  • Ridpath JR, Nakamura J, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde J, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA. 2007. Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. Cancer Res 67(23):11117-11122. doi:10.1158/0008-5472.CAN-07-3028 PMID:18056434
  • Rupert CP, Miller CT. 2007. An analysis of polynomial chaos approximations for modeling single-fluid-phase flow in porous medium systems. J Comput Phys 2226(2):2175-2205. PMID:18836519
  • Singleton D, Hunt M, Powell SN, Frontera-Suau R, Aitken MD. 2007. Stable-isotope probing with multiple growth substrates to determine substrate specificity of uncultivated bacteria. J Microbiol Methods 69(1):180-7. PMID:17267058
  • Tano K, Nakamura J, Asagoshi K, Arakawa H, Sonoda E, Braithwaite EK, Prasad R, Buerstedde J, Takeda S, Watanabe M, Wilson SH. 2007. Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. DNA Repair (Amst) 6(6):869-875. PMID:17363341
  • Woods CG, Burns AM, Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, Peters JM, Rusyn I. 2007. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase. Free Radic Biol Med 42(3):335-342. PMID:17210446

2006

  • Chao YE, Kupper LL, Serdar B, Egeghy PP, Rappaport SM, Nylander-French LA. 2006. Dermal exposure to jet fuel JP-8 significantly contributes to the production of urinary naphthols in fuel-cell maintenance workers. Environ Health Perspect 114(2):182-185. PMID:16451852 PMCID:PMC1367829
  • Chastain PD, Nakamura J, Swenberg JA, Kaufman DG. 2006. Nonrandom AP site distribution in highly proliferative cells. FASEB J 20(14):2612-4. PMID:17068113
  • Christman RF, Pfaender FK. 2006. Molecular implications of hydrophobic organic partitioning theory. Acta Hydrochimica et Hydrobiologica 34(4):367-374.
  • DeSimone MC, Harbourt D, Boysen G, Collins LB, Bradford BU, Han J, Swenberg JA, Threadgill DW, Rusyn I. 2006. Multi-strain study of trichoroethylene toxicity in mice. In: Superfund Basic Research Program Annual Meeting, December 11-12. La Jolla, CA.
  • Farthing MW, Kees CE, Jenkins EW, Miller CT. 2006. An evaluation of linearly implicit time discretization methods for approximating Richards' Equation. Chapter 218in: Proceedings of the 16th International Conference on Computational Methods in Water Resources (CMWR XVI), June 19-22. Copenhagen, Denmark.
  • Farthing MW, Kees CE, Russell TF, Miller CT. 2006. An ELLAM approximation for advective dispersive transport with nonlinear sorption. Adv Water Resour 29(5):657-75.
  • Farthing MW, Kees CE, Russell TF, Miller CT. 2006. An ELLAM approximation for advective- dispersive transport with nonlinear equilibrium and nonequilibrium sorption. Chapter 226in: Proceedings of the 16th International Conference on Computational Methods in Water Resources (CMWR XVI), June 19-22. Copenhagen, Denmark.
  • Gray WG, Miller CT. 2006. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 3. Single-fluid-phase flow. Adv Water Resour 29(11):1745-1765.
  • Han J, Harbourt D, Danell RM, Borchers CH, Rusyn I. 2006. High throughput metabolite profiling of serum from trichloroethylene-exposed mice by direct infusion FTICR-MS. In: Superfund Basic Research Program Annual Meeting, December 11-12. La Jolla, CA.
  • Kang-Sickel JC, Gold A, Ball LM, Karupiah J, Nylander-French LA, Parron V, Klapper DG, French JE. 2006. Detection of naphthalene keratin adducts in human skin using ELISA. J Mol Biol 38(Suppl.2):67-68.
  • Kim D, Andersen ME, Nylander-French LA. 2006. A dermatotoxicokinetic model of human exposures to jet fuel. Toxicol Sci 93(1):22-33. doi:10.1093/toxsci/kfl048 PMID:16801332
  • Kim D, Andersen ME, Nylander-French LA. 2006. Dermal absorption and penetration of jet fuel components in humans. Toxicol Lett 165(1):11-21. doi:10.1016/j.toxlet.2006.01.009 PMID:16497449
  • Kim S, Vermeulen R, Waidyanatha S, Johnson BA, Lan Q, Rothman N, Smith MT, Zhang L, Li G, Shen M, Yin S, Rappaport SM. 2006. Using urinary biomarkers to elucidate dose-related patterns of human benzene metabolism. Carcinogenesis 27(4):772-81. PMID:16339183
  • Kim S, Vermeulen R, Waidyanatha S, Johnson BA, Lan Q, Smith MT, Zhang L, Li G, Shen M, Yin S, Rothman N, Rappaport SM. 2006. Modeling human metabolism of benzene following occupational and environmental exposures. Cancer Epidemiol Biomarkers Prev 15(11):2246-52. PMID:17119053
  • Lin Y, McKelvey W, Waidyanatha S, Rappaport SM. 2006. Variability of albumin adducts of 1,4-benzoquinone, a toxic metabolite of benzene, in human volunteers. Biomarkers 11(1):14-27. doi:10.1080/13547500500382975 PMID:16484134
  • McClure JE, Adalsteinsson D, Wildenschild D, Gray WG, Miller CT. 2006. Computation of interfacial areas, common curve lengths, and interfacial curvatures from experimentally derived data. Chapter 224in: Proceedings of the 16th International Conference on Computational Methods in Water Resources (CMWR XVI), June 19-22. Copenhagen, Denmark.
  • Mechanic LM, Millikan RC, Player J, de Cotret AR, Winkel S, Worley K, Heard K, Heard K, Tse CJ, Keku T. 2006. Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study. Carcinogenesis 27(7):1377-1385. doi:10.1093/carcin/bgi330 PMID:16399771
  • Pachkowski BF, Winkel S, Kubota Y, Swenberg JA, Millikan RC, Nakamura J. 2006. XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Res 66(5):2860-2868. doi:10.1158/0008-5472.CAN-05-3388 PMID:16510609
  • Pan C, Luo L, Miller CT. 2006. An evaluation of lattice Boltzmann schemes for porous medium flow simulation. Computers & Fluids 35(8-9):898-909.
  • Pan C, McClure JE, Gray WG, Miller CT. 2006. Lattice boltzmann simulation of non-darcy flow. Chapter 248in: Proceedings of the 16th International Conference on Computational Methods in Water Resources (CMWR XVI), June 19-22. Copenhagen, Denmark.
  • Pleil JD, Funk WE, Rappaport SM. 2006. Residual indoor contamination from world trade center rubble fires as indicated by polycyclic aromatic hydrocarbon profiles. Environ Sci Technol 40(4):1172-1177. PMID:16572771
  • Pravecek TL, Christman RF, Pfaender FK. 2006. Microbial bioavailability of pyrene in three laboratory-contaminated soils under aerobic and anaerobic conditions. J Contam Hydrol 86:72-86. PMID:16574273
  • Reese JP, Long KR, Kelley CT, Gray WG, Miller CT. 2006. Simulating non-darcy flow through porous media using sundance. Chapter 148in: Proceedings of the 16th International Conference on Computational Methods in Water Resources (CMWR XVI), June 19-22. Copenhagen, Denmark.
  • Roper JC, Brown DM, Sullivan MA, Schoonhoven R, Swenberg JA, Pfaender FK. 2006. Epifluorescence microscopy and image analysis of high-level polycyclic aromatic hydrocarbon contamination in soils. Environ Toxicol Chem 25(12):3093-100. PMID:17220076
  • Serdar B, Tornero-Velez R, Echeverria D, Nylander-French LA, Kupper LL, Rappaport SM. 2006. Predictors of occupational exposure to styrene and styrene-7,8-oxide in the reinforced plastics industry. Occup Environ Med 63(10):707-12. PMID:16757507
  • Shen M, Lan Q, Zhang L, Chanock SJ, Li G, Vermeulen R, Rappaport SM, Guo W, Hayes RB, Linet MS, Yin S, Yeager M, Welch R, Forrest MS, Rothman N, Smith MT. 2006. Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity. Carcinogenesis 27(10):2083-2089. doi:10.1093/carcin/bgl061 PMID:16728435
  • Singleton D, Sangaiah R, Gold A, Ball LM, Aitken MD. 2006. Identification and quantification of uncultivated Proteobacteria associated with pyrene degradation in a bioreactor treating PAH-contaminated soil. Environ Microbiol 8(10):1736-1745. doi:10.1111/j.1462-2920.2006.01112.x PMID:16958754
  • Vermeulen R, Lan Q, Li G, Rappaport SM, Kim S, van Wendel de Joode B, Shen M, Bohong X, Smith MT, Zhang L, Yin S, Rothman G. 2006. Assessment of dermal exposure to benzene and toluene in shoe manufacturing by activated carbon cloth patches. J Environ Monit 8(11):1143-8. PMID:17075621
  • Ye W, Sangaiah R, Degen DE, Gold A, Jayaraj K, Koshlap KM, Boysen G, Williams J, Tomer KB, Ball LM. 2006. A 2-iminohydantoin from the oxidation of guanine. Chem Res Toxicol 19(4):506-10. PMID:16608161
  • Yokley K, Tran HT, Pekari K, Rappaport SM, Riihimaki V, Rothman N, Waidyanatha S, Schlosser PM. 2006. Physiologically-based pharmacokinetic modeling of benzene in humans: a Bayesian approach. Risk Anal 26(4):925-43. PMID:16948686
  • Yoshimura M, Kohzaki M, Nakamura J, Asagoshi K, Sonoda E, Hou E, Prasad R, Wilson SH, Tano K, Yasui A, Lan L, Seki M, Wood RD, Arakawa H, Buerstedde J, Hochegger H, Okada T, Hiraoka M, Takeda S. 2006. Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Mol Cell 24(1):115-125. doi:10.1016/j.molcel.2006.07.032 PMID:17018297 PMCID:PMC1868411

2005

  • Canter JA, Kallianpur AR, Parl FF, Millikan RC. 2005. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res 65(17):8028-8033. doi:10.1158/0008-5472.CAN-05-3774 PMID:16140977
  • Chao YE, Gibson RL, Nylander-French LA. 2005. Dermal exposure to jet fuel (JP-8) in US Air Force personnel. Ann Occup Hyg 49(7):639-645. PMID:16006502
  • Gray WG, Miller CT. 2005. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 1. Motivation and overview. Adv Water Resour 28(2):161-180.
  • Henderson AP, Barnes ML, Bleasdale C, Cameron R, Clegg W, Heath SL, Lindstrom AB, Rappaport SM, Waidyanatha S, Watson WP, Golding BT. 2005. Reactions of benzene oxide with thiols including glutathione. Chem Res Toxicol 18(2):265-270. doi:10.1021/tx049781y PMID:15720131
  • Jeong Y, Nakamura J, Upton PB, Swenberg JA. 2005. Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation. Nucleic Acids Res 33(19):6426-6434. doi:10.1093/nar/gki944 PMID:16282591 PMCID:PMC1283527
  • Jeong Y, Sangaiah R, Nakamura J, Pachkowski BF, Ranasinghe A, Gold A, Ball LM, Swenberg JA. 2005. Analysis of M(1)G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry. Chem Res Toxicol 18(1):51-60. PMID:15651849
  • Jeong Y, Swenberg JA. 2005. Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals. Free Radic Biol Med 39(8):1021-1029. PMID:16198229
  • Kim HS, Pfaender FK. 2005. Effects of microbially mediated redox conditions on PAH-soil interactions. Environ Sci Technol 39(23):9189-9196. PMID:16382941
  • Lan Q, Zhang L, Hakim F, Shen M, Memon S, Li G, Vermeulen R, Smith MT, Rappaport SM, Hayes RB, Linet MS, Yin S, Rothman N, Rabkin CS. 2005. Lymphocyte toxicity and T cell receptor excision circles in workers exposed to benzene. Chem Biol Interact 153-154:111-115. PMID:15935806
  • Lan Q, Zhang L, Shen M, Smith MT, Li G, Vermeulen R, Rappaport SM, Forrest MS, Hayes RB, Linet MS, Dosemeci M, Alter BP, Weinberg RS, Yin S, Yeager M, Welch R, Waidyanatha S, Kim S, Chanock SJ, Rothman N. 2005. Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene. Cancer Res 65(20):9574-9581. doi:10.1158/0008-5472.CAN-05-1419 PMID:16230423
  • Li H, Pan C, Miller CT. 2005. Pore-scale investigation of viscous coupling effects for two-phase flow in porous media. Physical Review E 72(2pt2):26705-26719. PMID:16196749
  • Li Y, Millikan RC, Bell DA, Cui L, Tse CJ, Newman B, Conway K. 2005. Polychlorinated biphenyls, cytochrome P450 1A1 (CYP1A1) polymorphisms, and breast cancer risk among African American women and white women in North Carolina: a population-based case-control study. Breast Cancer Research 7(1):R12-R18. PMID:15642161
  • Lin C, Leow H, Huang S, Nakamura J, Swenberg JA, Lin P. 2005. Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells. Chem Res Toxicol 18(2):257-264. PMID:15720130
  • Miller CT, Gray WG. 2005. Thermodynamically constrained averaging theory approach for modeling flow and transport phenomena in porous medium systems: 2. Foundation. Adv Water Resour 28(2):181-202.
  • Olea RA, Christakos G. 2005. Duration of urban mortality for the 14th-century black death epidemic. Human Biology 77(3):291-303. PMID:16392633
  • Pravecek TL, Christman RF, Pfaender FK. 2005. Impact of imposed anaerobic conditions and microbial activity on aqueous-phase solubility of polycyclic aromatic hydrocarbons from soil. Environ Toxicol Chem 24(2):286-293. PMID:15719987
  • Rappaport SM, Waidyanatha S, Yeowell-O'Connell K, Rothman N, Smith MT, Zhang L, Qu Q, Shore R, Li G, Yin S. 2005. Protein adducts as biomarkers of human benzene metabolism. Chem Biol Interact 153-154:103-109. PMID:15935805
  • Singleton D, Powell SN, Sangaiah R, Gold A, Ball LM, Aitken MD. 2005. Stable-isotope probing of bacteria capable of degrading salicylate, naphthalene, or phenanthrene in a bioreactor treating contaminated soil. Appl Environ Microbiol 71(3):1202-1209. doi:10.1128/AEM.71.3.1202-1209.2005 PMID:15746319 PMCID:PMC1065189
  • Waidyanatha S, Rappaport SM. 2005. Investigation of cysteinyl protein adducts of benzene diolepoxide. Chem Biol Interact 153-154:261-266. PMID:15935825
  • Waidyanatha S, Sangaiah R, Rappaport SM. 2005. Characterization and quantification of cysteinyl adducts of benzene diol epoxide. Chem Res Toxicol 18(7):1178-1185. PMID:16022511
  • Wu R, Waidyanatha S, Henderson AP, Serdar B, Zheng Y, Rappaport SM. 2005. Determination of dihydroxynaphthalenes in human urine by gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 826(1-2):206-213. doi:10.1016/j.jchromb.2005.08.022 PMID:16169295
  • Ye W, Sangaiah R, Degen DE, Gold A, Jayaraj K, Koshlap KM, Boysen G, Ball LM. 2005. A 2-Iminohydantoin is the major product from DMDO oxidation of Guanine. In: Superfund Basic Research Program Annual Meeting, January 12-13. New York Academy of Medicine, New York, NY.

2004

  • Casteel MJ, Jayaraj K, Gold A, Ball LM, Sobsey MD. 2004. Photoinactivation of hepatitis A virus by synthetic porphyrins. Photochemistry and Photobiology 80(2):294-300. PMID:15362943
  • Chao YE, Nylander-French LA. 2004. Determination of keratin protein in a tape-stripped skin sample from jet fuel exposed skin. Ann Occup Hyg 48(1):65-73. PMID:14718347
  • Christakos G. 2004. A sociological approach to the state of stochastic hydrogeologys. Stochastic Environmental Research and Risk Assessment 18(4):274-277.
  • Christakos G, Kolovos A, Serre ML, Vukovich F. 2004. Total ozone mapping by integrating databases from remote sensing instruments and empirical models. IEEE Transactions on Geoscience and Remote Sensing 42(5):991-1008.
  • Douaik A, Van Meirvenne M, Toth T, Serre ML. 2004. Space-time mapping of soil salinity using probabilistic bayesian maximum entropy. Stochastic Environmental Research and Risk Assessment 18(4):219-227.
  • Fowler KR, Kelley CT, Miller CT, Kees CE, Darwin RW, Reese JP, Farthing MW, Reed MS. 2004. Solution of a well-field design problem with implicit filtering. Optimization and Engineering 5(2):207-234.
  • Gray WG, Miller CT. 2004. Examination of Darcy's law for flow in porous media with variable porosity. Environ Sci Technol 38(22):5895-5901. PMID:15573587
  • Ham AL, Engelward BP, Koc H, Sangaiah R, Meira LB, Samson LD, Swenberg JA. 2004. New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N-6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo. DNA Repair (Amst) 3(3):257-265. PMID:15177041
  • Hu C, Wu M, Chao M, Pan C, Wang C, Swenberg JA, Wu K. 2004. Comparison of analyses of urinary 8-hydroxy-2 '-deoxyguanosine by isotope-dilution liquid chromatography with electrospray tandem mass spectrometry and by enzyme-linked immunosorbent assay. Rapid Commun Mass Spectrom 18(4):505-510. PMID:14966860
  • Johnson DN, Pedit JA, Miller CT. 2004. Efficient, near-complete removal of DNAPL from three- dimensional, heterogeneous porous media using a novel combination of treatment technologies. Environ Sci Technol 38(19):5149-5156. PMID:15506211
  • Kolovos A, Christakos G, Hristopulos D, Serre ML. 2004. Methods for generating non-separable spatiotemporal covariance models with potential environmental applications. Adv Water Resour 27(8):815-830.
  • Kovitz JL, Christakos G. 2004. Assimilation of fuzzy data by the BME method. Stochastic Environmental Research and Risk Assessment 18(2):79-90.
  • Kovitz JL, Christakos G. 2004. Spatial statistics of clustered data. Stochastic Environmental Research and Risk Assessment 18(3):147-166.
  • Lan Q, Zhang L, Li G, Vermeulen R, Weinberg RS, Dosemeci M, Rappaport SM, Shen M, Alter BP, Wu Y, Kopp W, Waidyanatha S, Rabkin CS, Guo W, Chanock SJ, Hayes RB, Linet MS, Kim S, Yin S, Rothman N, Smith MT. 2004. Hematotoxicity in workers exposed to low levels of benzene. Science 306(5702):1774-1776. doi:10.1126/science.1102443 PMID:15576619 PMCID:PMC1256034
  • Landrigan PJ, Lioy PJ, Thurston G, Berkowitz GS, Chen L, Chillrud SN, Gavett SH, Georgopoulos PG, Geyh AS, Levin SM, Perera F, Rappaport SM, Small C. 2004. Health and environmental consequences of the world trade center disaster. Environ Health Perspect 112(6):731-739. PMID:15121517
  • Law DG, Serre ML, Christakos G, Leone PA, Miller WC. 2004. Spatial analysis and mapping of sexually transmitted diseases to optimise intervention and prevention strategies. Sex Transm Infect 80(4):294-299. PMID:15295129
  • Li Y, Millikan RC, Bell DA, Cui L, Tse CJ, Newman B, Conway K. 2004. Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women. Breast Cancer Research 6(4):R460-R473. PMID:15217514
  • Lin P, Sangaiah R, Ranasinghe A, Ball LM, Swenberg JA, Gold A. 2004. Synthesis of chlorinated and non-chlorinated biphenyl-2,3-and 3,4-catechols and their [H-2(3)]-isotopomers. Org Biomol Chem 2(18):2624-2629. PMID:15351827
  • Mattorano DA, Kupper LL, Nylander-French LA. 2004. Estimating dermal exposure to jet fuel (naphthalene) using adhesive tape strip samples. Ann Occup Hyg 48(2):139-146. PMID:14990435
  • Millikan RC, Player J, de Cotret AR, Moorman P, Pittman G, Vannappagari V, Tse CJ, Keku T. 2004. Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. Breast Cancer Research 6(4):R264-R274. PMID:15217492
  • Pan C, Hilpert M, Miller CT. 2004. Lattice-Boltzmann simulation of two-phase flow in porous media. Water Resour Res 40(1)artno.:W01501.
  • Pan C, Prins JF, Miller CT. 2004. A high-performance lattice Boltzmann implementation to model flow in porous media. Computer Physics Communications 158(2):89-105.
  • Pleil JD, Vette AF, Johnson BA, Rappaport SM. 2004. Air levels of carcinogenic polycyclic aromatic hydrocarbons after the World Trade Center disaster. Proc Natl Acad Sci U S A 101(32):11685-11688. PMID:15280534
  • Pleil JD, Vette AF, Johnson BA, Rappaport SM. 2004. Assaying particle-bound polycyclic aromatic hydrocarbons from archived PM2.5 filters. J Chromatogr A 1033(1):9-17. PMID:15072286
  • Rappaport SM, Kupper LL. 2004. Variability of environmental exposures to volatile organic compounds. J Expo Sci Environ Epidemiol 14(1):92-107. PMID:14726948
  • Rappaport SM, Waidyanatha S, Serdar B. 2004. Naphthalene and its biomarkers as measures of occupational exposure to polycyclic aromatic hydrocarbons. J Environ Monit 6(5):413-416. PMID:15152308
  • Rusyn I, Asakura S, Pachkowski BF, Bradford BU, Denissenko MF, Peters JM, Holland SM, Reddy JK, Cunningham ML, Swenberg JA. 2004. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: Identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer Res 64(3):1050-1057. PMID:14871837
  • Savelieva EA, Demyanov VV, Kanevski MF, Serre ML, Christakos G. 2004. BME application for uncertainty assessment of the Chernobyl fallouts. Geoderma 128(3-4):312-324.
  • Serdar B, Egeghy PP, Gibson RL, Rappaport SM. 2004. Dose-dependent production of urinary naphthols among workers exposed to jet fuel (JP-8). Environ Health Perspect 46(3):234-244. PMID:15307122
  • Slikker W, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K, Andersen ME. 2004. Dose-dependent transitions in mechanisms of toxicity. Toxicol Appl Pharmacol 201(3):203-225. PMID:15582645
  • Swenberg JA. 2004. Toxicological considerations in the application and interpretation of DNA adducts in epidemiological studies. IARC Sci Publ 157:237-246. PMID:15055299
  • Vermeulen R, Li G, Lan Q, Dosemeci M, Rappaport SM, Bohong X, Smith MT, Zhang L, Hayes RB, Linet MS, Mu R, Wang L, Xu J, Yin S, Rothman N. 2004. Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China. Ann Occup Hyg 48(2):105-116. PMID:14990432
  • Waidyanatha S, Rothman N, Li G, Smith MT, Yin S, Rappaport SM. 2004. Rapid determination of six urinary benzene metabolites in occupationally exposed and unexposed subjects. Anal Biochem 327(2):184-199. PMID:15051535
  • Waidyanatha S, Zheng Y, Serdar B, Rappaport SM. 2004. Albumin adducts of naphthalene metabolites as biomarkers of exposure to polycyclic aromatic hydrocarbons. Cancer Epidemiol Biomarkers Prev 13(1):117-124. PMID:14744742
  • Zielinska-Park J, Nakamura J, Swenberg JA, Aitken MD. 2004. Aldehydic DNA lesions in calf thymus DNA and HeLa S3 cells produced by bacterial quinone metabolites of fluoranthene and pyrene. Carcinogenesis 25(9):1727-1733. PMID:15117810

2003

  • Albertini R, Clewell H, Himmelstein MW, Morinello EJ, Olin S, Preston J, Scarano L, Smith MT, Swenberg JA, Tice RR, Travis C. 2003. The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene. Regul Toxicol Pharmacol 37(1):105-132. PMID:12662914
  • Anderson DM, McLaughlin RM, Miller CT. 2003. The averaging of gravity currents in porous media. Physics of Fluids 15(10):2810-2829.
  • Barbin A, Ohgaki H, Nakamura J, Kurrer M, Kleihues P, Swenberg JA. 2003. Endogenous deoxyribonucleic acid (DNA) damage in human tissues: A comparison of ethenobases with aldehydic DNA lesions. Cancer Epidemiol Biomarkers Prev 12(11):1241-1247. PMID:14652288
  • Choi K, Serre ML, Christakos G. 2003. Efficient mapping of California mortality fields at different spatial scales. J Expo Sci Environ Epidemiol 13(2):120-133. PMID:12679792
  • Christakos G. 2003. Another look at the conceptual fundamentals of porous media upscaling. Stochastic Environmental Research and Risk Assessment 17(5):276-290.
  • Christakos G. 2003. Critical conceptualism in environmental modeling and prediction. Environ Sci Technol 37(20):4685-4693. PMID:14594379
  • Christakos G. 2003. Soil behaviour under dynamic loading conditions: experimental procedures and statistical trends. Stochastic Environmental Research and Risk Assessment 17(3):175-190.
  • Christakos G. 2003. The role of conceptual framworks in hydrologic research and development. In: Calibration & Reliability in Groundwater Modelling: A Few Steps Closer to Reality. IAHS Publishing, 277 Oxfordshire, United Kingdom. pp.277-285.
  • Christakos G, Kolovos A, Serre ML, Vukovich F. 2003. Generating high spatial resolution analyses of SBUV stratospheric ozone for calculating the tropospheric ozone residual (TOR). In: Proceedings of the IEEE/IGARRA, 21-25 July. Toulouse, France.
  • Dalla E, Hilpert M, Miller CT, Pitea D. 2003. Modelling the dissolution of non-aqueous phase liquid blobs in sphere packings. Ann Chim 93(7-8):631-638. PMID:12940596
  • Egeghy PP, Hauf-Cabalo L, Gibson RL, Rappaport SM. 2003. Benzene and naphthalene in air and breath as indicators of exposure to jet fuel. Occup Environ Med 60(12):969-976. PMID:14634191
  • Farthing MW, Kees CE, Coffey TS, Kelley CT, Miller CT. 2003. Efficient steady-state solution techniques for variably saturated groundwater flow. Adv Water Resour 26(8):833-849.
  • Farthing MW, Kees CE, Miller CT. 2003. Mixed finite element methods and higher order temporal approximations for variably saturated groundwater flow. Adv Water Resour 26(4):373-394.
  • Gold A, Nam T, Jayaraj K, Sangaiah R, Klapper DG, Ball LM, French JE, Nylander-French LA. 2003. Synthesis of S-aryl-D,L-cysteines and incorporation into keratin sequences. Organic Preparations and Procedures International 35(4):375-382.
  • Hilpert M, Glantz R, Miller CT. 2003. Calibration of a pore-network model by a pore-morphological analysis. Transp Porous Media 51(3):267-285.
  • Hilpert M, Miller CT, Gray WG. 2003. Stability of a fluid-fluid interface in a biconical pore segment. Journal of Colloid and Interface Science 267(2):397-407. PMID:14583218
  • Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH. 2003. Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. DNA Repair (Amst) 2(1):27-48. PMID:12509266
  • Imhoff PT, Farthing MW, Miller CT. 2003. Modeling NAPL dissolution fingering with upscaled mass transfer rate coefficients. Adv Water Resour 26(10):1097-1111.
  • Kanney JF, Miller CT, Barry DA. 2003. Comparison of fully coupled approaches for approximating nonlinear transport and reaction problems. Adv Water Resour 26(4):353-372.
  • Kanney JF, Miller CT, Kelley CT. 2003. Convergence of iterative split-operator approaches for approximating nonlinear reactive transport problems. Adv Water Resour 26(3):247-261.
  • Kees CE, Miller CT, Jenkins EW, Kelley CT. 2003. Versatile two-level Schwarz preconditioners for multiphase flow. Computational Geosciences 7(2):91-114.
  • Kolovos A, Christakos G, Serre ML, Hristopulos D. 2003. Representations of Non-Separable Spatiotemporal Covariance Models. In: Proceedings of the AGU (American Geophysical Union) Fall Meeting, December 8-12. San Francisco, CA.
  • Law AM, Aitken MD. 2003. Bacterial chemotaxis to naphthalene desorbing from a nonaqueous liquid. Appl Environ Microbiol 69(10):5968-5973. PMID:14532051
  • Law DG, Serre ML, Christakos G, Leone PA, Miller WC. 2003. Analyzing and Mapping the Spatial Distribution of Sexually Transmitted Diseases for Public Health Intervention. In: Proceedings of the Congress of the international Society for Sexually Transmitted Disease Research, July 27-30. Ottawa, Canada.
  • Law DG, Serre ML, Leone PA, Miller WC. 2003. Spatiotemporal changes in chlamydial infection patterns and persistence of "the core". In: Proceedings of the Congress of the international Society for Sexually Transmitted Disease Research, July 27-30. Ottawa, Canada.
  • Lee SJ, Serre ML, Christakos G. 2003. Integrating soil pH as a risk factor in the spatial mapping of arsenic distributions in New England groundwater. In: Proceedings of the Superfund Basic Research Program Annual Meeting: Integration Perspectives, November 9-12, 2003. Dartmouth College, Hanover, NH.
  • Li Y, Boysen G, Dicheva ND, Upton PB, Swenberg JA. 2003. Effects of Free Unmodified Purine Basis, Guanine and Adenine, on Ionization of Three N-7 Guanine DNA Adducts Using LC/ESI/MS/MS. In: Proceedings of the American Society of Mass Spectrometry, 51st Annual Conference.
  • Lin P, Nakamura J, Yamaguchi S, Asakura S, Swenberg JA. 2003. Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA. Carcinogenesis 24(6):1133-1141. PMID:12807746
  • Mountcastle SB, Serre ML, Ryder RW, Weir SS. 2003. A geographic analysis of high STI Transmission aresa in Cumberland County, North Carolina. In: Proceedings of the Congress of the international Society for Sexually Transmitted Disease Research, July 27-30. Ottawa, Canada.
  • Nakamura J, Asakura S, Hester SD, de Murcia G, Caldecott KW, Swenberg JA. 2003. Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time. Nucleic Acids Res 31(17):e104. PMID:12930978
  • Nakamura J, Purvis ER, Swenberg JA. 2003. Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells. Nucleic Acids Res 31(6):1790-1795. PMID:12626721
  • Nakamura J, Swenberg JA. 2003. Aldehyde Reactive Probe-Slot Blot Assay to quantitate DNA lesions caused by oxidative stress. In: Methods in Biological Oxidative Stress. Humana Press, pp.109-115.
  • Pachkowski BF, Nakamura J, Li Y, Sangaiah R, Gold A, Swenberg JA. 2003. An LC/MS Approach to the Differentiation of Aldehydic Deoxyribose Lesions. In: Proceedings of the American Association for Cancer Research Annual Meeting, 2003.
  • Savelieva EA, Demyanov VV, Kanevski VM, Serre ML, Christakos G. 2003. BME application for uncertainty assessment of the Chernobyl Fallouts. In: Proceedings Pedometrics 2003, the 5th Conference of the Provisional Commission on Pedometrics of the International Union of Soil Sciences, "Applications of Pedometrics", September 10-12. Reading, United Kingdom.
  • Serdar B, Egeghy PP, Waidyanatha S, Gibson RL, Rappaport SM. 2003. Urinary biomarkers of exposure to jet fuel (JP-8). Environ Health Perspect 111(14):1760-1764. PMID:14594628
  • Serdar B, Waidyanatha S, Zheng Y, Rappaport SM. 2003. Simultaneous determination of urinary 1- and 2-naphthols, 3- and 9-phenanthrols, and 1-pyrenol in coke oven workers. Biomarkers 8(20:93-109. PMID:12775495
  • Serre ML, Christakos G. 2003. Efficient BME estimation of subsurface hydraulic properties using measurements of water table elevation in unidirectional flow. In: Calibration & Reliability in Groundwater Modelling: A Few Steps Closer to Reality. IAHS Publishing, 277 Oxfordshire, United Kingdom. pp.321-327.
  • Serre ML, Christakos G, Kolovos A, Vukovich F. 2003. Imaging ozone distributions across space-time using satellite data and physical information. In: Proceedings of the AGU (American Geophysical Union) Fall Meeting, December 8-12. San Francisco, CA.
  • Serre ML, Christakos G, Li H, Miller CT. 2003. A BME solution of the inverse problem for saturated groundwater flow. Stochastic Environmental Research and Risk Assessment 17(6):354-369.
  • Serre ML, Kolovos A, Christakos G, Modis K. 2003. An application of the holistochastic human exposure methodology to naturally occurring arsenic in Bangladesh drinking water. Risk Anal 23(3):515-528. PMID:12836844
  • Tsai CH, Lin P, Troester MA, Rappaport SM. 2003. Formation and removal of pentachlorophenol-derived protein adducts in rodent liver under acute, multiple, and chronic dosing regimens. Toxicol Sci 73(1):26-35. PMID:12700421
  • Vanderford M, Pfaender FK. 2003. Toxicity, Persistence, and Influence of Pyrene-4,5-Dione on PAH Biodegradation. In: Proceedings of the Battelle Bioremediation Conference.
  • Waidyanatha S, Zheng Y, Rappaport SM. 2003. Determination of polypyclic aromatic hydrocarbons in urine of coke oven workers by headspace solid phase microextraction and gas chromatography-mass spectrometry. Chem Biol Interact 145(2):165-174. PMID:12686493
  • Williams DE, Bailey GS, Reddy A, Hendricks JD, Oganesian A, Orner GA, Pereira CB, Swenberg JA. 2003. The rainbow trout (Oncorhynchus mykiss) tumor model: recent applications in low-dose exposures to tumor initiators and promoters. Toxicol Pathol 31(Suppl.1):58-61. PMID:12597433

2002

  • Barry DA, Prommer H, Miller CT, Engesgaard PK, Brun A, Zheng C. 2002. Modelling the fate of oxidisable organic contaminants in groundwater. Adv Water Resour 25(8):945-983.
  • Christakos G. 2002. On a deductive logic-based spatiotemporal random field theory. Probability Theory and Mathematical Statistics 66:54-65.
  • Christakos G. 2002. On the assimilation of uncertain physical knowledge bases: Bayesian and non-Bayesian techniques. Adv Water Resour 25(8-12):1257-1274.
  • Christakos G. 2002. The study of uncertainty in life support systems. In: Encyclopedia of Life Support Systems. UNESCO, London, United Kingdom.
  • Dalla E, Hilpert M, Miller CT. 2002. Computation of the interfacial area for two-fluid porous medium systems. J Contam Hydrol 56(1-2):25-48. PMID:12076022
  • Egeghy PP, Nylander-French LA, Gwin KK, Hertz-Picciotto I, Rappaport SM. 2002. Self-collected breath sampling for monitoring low-level benzene exposures among automobile mechanics. Ann Occup Hyg 46(5):489-500. PMID:12176763
  • Farthing MW, Kees CE, Miller CT. 2002. Mixed finite element methods and higher order temporal approximations. Adv Water Resour 25(1):85-101.
  • Frontera-Suau R, Jeong K, Park J, Long T, Law A, Walters GW, Aitken MD. 2002. PAH biodegradation and microbial population dynamics in a bench-scale bioreactor treating soil from a former manufactured gas plant. In: Proceedings of The 102nd General Meeting of the American Society for Microbiology, May 19-23. Salt Lake, UT.
  • Hill EH, Kupper LL, Miller CT. 2002. Evaluation of path-length estimators for characterizing multiphase systems using polyenergetic X-ray absorptiometery. Soil Science 167(11):703-719.
  • Imhoff PT, Farthing MW, Gleyzer SN, Miller CT. 2002. The evolving interface between clean and NAPL-contaminated regions in two-dimensional porous media. Water Resour Res 38(6):1093.
  • Kees CE, Miller CT. 2002. Higher order time integration methods for two-phase flow. Adv Water Resour 25(2):159-177.
  • Koc H, Swenberg JA. 2002. Applications of mass spectrometry for quantitation of DNA adducts. J Chromatogr B Analyt Technol Biomed Life Sci 778(1-2):323-343. PMID:12376138
  • Kolovos A, Christakos G, Serre ML, Miller CT. 2002. Computational Bayesian maximum entropy solution of a stochastic advection-reaction equation in the light of site-specific information. Water Resour Res 38(12):1318.
  • Kukich DM, Schoonhoven R, Christman RF, Pfaender FK. 2002. Interactions of Natural Organic Matter with the Mineral Matrix of Soil. In: Proceedings of the International Humic Substances Society Meeting. Boston, MA.
  • Lin P, La DK, Upton PB, Swenberg JA. 2002. Analysis of DNA adducts in rats exposed to pentachlorophenol. Carcinogenesis 23(2):365-369. PMID:11872646
  • Mayer AS, Kelley CT, Miller CT. 2002. Optimal design for problems involving flow and transport in saturated subsurface systems. Adv Water Resour 25(8-12):1233-1256.
  • Miller CT, Gray WG. 2002. Hydrogeological research: just getting started. Ground Water 40(3):224-31;discussion317-9. PMID:12019637
  • Millikan RC. 2002. The changing face of epidemiology in the genomics era. Epidemiology 13(4):472-480. PMID:12094104
  • Morinello EJ, Ham AL, Ranasinghe A, Nakamura J, Upton PB, Swenberg JA. 2002. Molecular dosimetry and repair of N2,3-ethenoguanine in rats exposed to vinyl chloride. Cancer Res 62:5189-5195. PMID:12234983
  • Morinello EJ, Koc H, Ranasinghe A, Swenberg JA. 2002. Differential induction of N2,3-ethenoguanine in rat brain and liver after exposure to vinyl chloride. Cancer Res 62:5183-5188.
  • Nam T, Sangaiah R, Gold A, Lacks GD, Nylander-French LA, French JE. 2002. Synthesis of FMOC-protected S-arylcysteines and modified keratin sequence peptides as specific epitopes as immunogens. Polycyclic Aromatic Compounds 22(3-4):239-248.
  • Pan C, Hilpert M, Miller CT. 2002. Pore-scale modeling of saturated permeabilities in random sphere packings. Physical Review A 64:066702. PMID:11736308
  • Pedit JA, Marx RB, Miller CT, Aitken MD. 2002. Quantitative analysis of experiments on bacterial chemotaxis to naphthalene. Biotechnol Bioeng 78(6):626-634. PMID:11992528
  • Pfaender FK. 2002. Interactions of Soil Mineral Matrices with Soil Organic Carbon and Microorganisms. In: Proceedings of the Workshop on Bound Residues of Organic Compounds in the Soil Environment. Lancaster, United Kingdom.
  • Prommer H, Davis GB, Barry DA, Miller CT. 2002. Modelling the Fate of Petroleum Hydrocarbons in Groundwater. In: Proceedings of the Australian National Environmental Protection Council (NEPC), Site Contamination Technical Workshop, May 13-15. Adelaide, Australia.
  • Rappaport SM, Waidyanatha S, Qu Q, Shore R, Jin X, Cohen B, Chen L, Melikian AA, Li G, Yin S, Yan H, Xu B, Mu R, Li Y, Zhang X, Li K. 2002. Albumin adducts of benzene oxide and 1,4-benzoquinone as measures of human benzene metabolism. Cancer Res 62(5):1330-1337. PMID:11888901
  • Rappaport SM, Yeowell-O'Connell K, Smith MT, Dosemeci M, Hayes RB, Zhang L, Li G, Yin S, Rothman N. 2002. Non-linear production of benzene oxide-albumin adducts with human exposure to benzene. J Chromatogr A 778:367-374. PMID:12376141
  • Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Wu J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. 2002. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A 99(14):6860-6865. PMID:11983862
  • Swenberg JA, Georgieva NI, Ham AL, Koc H, Morinello EJ, Ranasinghe A, Upton PB, Walker V. 2002. Linking pharmacokinetics and biomarker data to mechanism of action in risk assessment. Human and Ecological Risk Assessment: An International Journal 8(6):1315-1338.
  • Swenberg JA, Ham AL, Koc H, La DK, Morinello EJ, Pachkowski BF, Ranasinghe A, Upton PB. 2002. Methods for measuring DNA adducts and abasic sites II: methods for measurement of DNA adducts. Curr Protoc Toxicol Chapter3:Unit3.9. doi:10.1002/0471140856.tx0309s12 PMID:23045080
  • Swenberg JA, Ham AL, McDorman KS, Morinello EJ, Nakamura J, Schoonhoven R. 2002. Methods for measuring DNA adducts and abasic sites I: isolation, purification, and analysis of DNA adducts in intact DNA. Curr Protoc Toxicol Chapter3:Unit3.8. doi:10.1002/0471140856.tx0308s12 PMID:23045079
  • Toraason M, Andersen ME, Bogdanffy MS, Dankovic D, Faustman EM, Foster P, Frederick C, Haber L, Kimmel CA, Lewis S, McClellan R, Melnick R, Mirer F, Morgan K, Schaeffer V, Silbergeld EK, Slikker W, Swenberg JA, Vainio H. 2002. Improving risk assessment: toxicological research needs. Human and Ecological Risk Assessment: An International Journal 8(6):1405-1419. doi:10.1080/20028091057439
  • Troester MA, Lindstrom AB, Waidyanatha S, Kupper LL, Rappaport SM. 2002. Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone. Toxicol Sci 68(2):314-321. PMID:12151627
  • Tsai CH, Lin P, Waidyanatha S, Rappaport SM. 2002. Fractionation of protein adducts in rats and mice dosed with[(14)C]pentachlorophenol. Arch Toxicol 76(11):628-633. PMID:12415425
  • Waidyanatha S, Troester MA, Lindstrom AB, Rappaport SM. 2002. Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats. Chem Biol Interact 141(3):189-210. PMID:12385719

2001

  • Christakos G. 2001. Stochastic modelling in human exposure. In: Encyclopedia of Environmetrics. J. Wiley & Sons, Ltd., Chichester, United Kingdom. pp.1290-1296.
  • Christakos G, Serre ML, Demyanov VV, Kanevski VM, Savelieva EA, Chernov S, Timonin V. 2001. BME analysis of Neural network residual data from the Chernobyl fallout: Bayesian and Non-Bayesian approaches. In: Geostatistics for Environmental Applications. Kluwer Academy Publications, Dordrecht, Netherlands. pp.509-510.
  • Christakos G, Serre ML, Kovitz JL. 2001. BME representations of particulate matter in the state of California. J Geophys Res Atmos 106(D9):9717-9732.
  • D'Or D, Bogaert P, Christakos G. 2001. Applications of BME to soil texture mapping. Stochastic Environmental Research and Risk Assessment 15(1):87-100.
  • Duell EJ, Millikan RC, Pittman G, Winkel S, Lunn RM, Tse CJ, Eaton A, Mohrenweiser HW, Newman B, Bell DA. 2001. Polymorphisms in the DNA repair gene XRCC1 and breast cancer. Cancer Epidemiol Biomarkers Prev 10:217-222. PMID:11303590
  • Ham AL, Zhan C, Koc H, Hass RJ, Swenberg JA. 2001. Analysis of 1,N6-ethenodeoxyguanosine by immunoaffinity/LC/MS/MS. In: Proceedings of the 49th ASMS (American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics. June 4-7. Chicago, IL.
  • Hill EH, Moutier M, Alfaro J, Miller CT. 2001. Remediation of DNAPL pools using dense brine barrier strategies. Environ Sci Technol 35(14):3031-3039. PMID:11478259
  • Hilpert M, McBride JF, Miller CT. 2001. Investigation of the residual-funicular nonwetting-phase-saturation relation. Adv Water Resour 24(2):157-177.
  • Hilpert M, Miller CT. 2001. Pore-morphology-based simulation of drainage in totally wetting porous media. Adv Water Resour 24(3-4):243-255.
  • Hristopulos D, Christakos G. 2001. Practical calculation of non-Gaussian multivariate moments in BME analysis. Math Geol 33(5):543-568.
  • Jenkins EW, Kelley CT, Miller CT, Kees CE. 2001. An aggregation-based domain decomposition preconditioner for groundwater flow. SIAM Journal on Scientific Computing 23:430-441.
  • Kazunga C, Aitken MD, Gold A, Sangaiah R. 2001. Fluoranthene-2,3- and -1,5-diones are novel products from the bacterial transformation of fluoranthene. Environ Sci Technol 35(5):917-922. PMID:11351535
  • Lin P, Nakamura J, Yamaguchi S, La DK, Swenberg JA. 2001. Oxidative damage and direct adducts in calf thymus DNA induced by the pentachlorophenol metabolites, tetrachlorohydroquinone and tetrachloro-1,4-benzoquinone. Carcinogenesis 22(4):627-634. PMID:11285199
  • Lin P, Nakamura J, Yamaguchi S, La DK, Upton PB, Swenberg JA. 2001. Induction of direct adducts, apurinic/apyrimidinic sites and oxidized bases in nuclear DNA of human HeLa S3 tumor cells by tetrachlorohydroquinone. Carcinogenesis 22(4):635-639. PMID:11285200
  • Morinello EJ, Ham AL, Ranasinghe A, Sangaiah R, Swenberg JA. 2001. Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay. Chem Res Toxicol 14(3):327-334. PMID:11258983
  • Nam T, Sangaiah R, Gold A, Lacks GD, Nylander-French LA, French JE. 2001. Synthesis of FMOC-protected S-aryclysteines and modified keratin sequence peptides as specific epitopes as immunogens. In: Proceedings of the 18th International Symposiium on Polycyclic Aromatic Compounds, Sept 9-13. Cincinnati, OH.
  • Nylander-French LA, Lacks GD, Mattorano DA. 2001. Quantification of naphthalene dermal exposure using non-invasive tape stripping of the stratum corneum, extraction, and normalization against keratin. Arbete och Halsa 10:23-24.
  • Roper JC, Pfaender FK. 2001. Pyrene and chrysene fate in surface soil and sand microcosms. Environ Toxicol Chem 20(2):223-230. PMID:11351420
  • Schulz MR, Hertz-Picciotto I, Todd L, Ball LM. 2001. Reconciling animal and human data in a cancer risk assessment of acrylonitrile. Scand J Work Environ Health 27(1):14-20. PMID:11266142
  • Serre ML, Christakos G, Howes J, Gamal A. 2001. Powering an Egyptian air quality information system with the BME space/time analysis toolbox: Results from the Cairo baseline year study. In: Geostatistics for Environmental Applications. Kluwer Academy Publications, Dordrecht, Netherlands. pp.91-100.
  • Taylor DJ, Kupper LL, Rappaport SM, Lyles RH. 2001. A mixture model for occupational exposure mean testing with a limit of detection. Biometrics 57(3):681-699. PMID:11550915
  • Troester MA, Kupper LL, Rappaport SM. 2001. Comparison of non-linear and linear models for estimating haemoglobin adduct stability. Biomarkers 6(4):251-261. PMID:23889277
  • Tsai CH, Lin P, Waidyanatha S, Rappaport SM. 2001. Characterization of metabolic activation of pentachlorophenol to quinones and semiquinones in rodent liver. Chem Biol Interact 134(1):55-71. PMID:11248222
  • Waidyanatha S, Rothman N, Fustinoni S, Smith MT, Hayes RB, Bechtold WE, Dosemeci M, Li G, Yin S, Rappaport SM. 2001. Urinary benzene as a biomarker of exposure among occupationally exposed and unexposed subjects. Carcinogenesis 22:279-286. PMID:11181449
  • Walters GW, Aitken MD. 2001. Surfactant-enhanced solubilization and anaerobic biodegradation of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane (DDT) in contaminated soil. Water Environ Res 73(1):15-23. PMID:11558297
  • Weaver MA, Kupper LL, Taylor DJ, Kromhout H, Susi P, Rappaport SM. 2001. Simultaneous assessment of occupational exposures from multiple worker groups. Occupational Hygiene 45(7):525-542. PMID:11583655
  • Yeowell-O'Connell K, Rothman N, Waidyanatha S, Smith MT, Hayes RB, Li G, Bechtold WE, Dosemeci M, Zhang L, Yin S, Rappaport SM. 2001. Protein adducts of 1,4-benzoquinone and benzene oxide among smokers and nonsmokers exposed to benzene in China. Cancer Epidemiol Biomarkers Prev 10:831-838. PMID:11489749

2000

  • Boivin-Angele S, Lefrancois L, Froment O, Spiethoff A, Bogdanffy MS, Wegener K, Wesch H, Barbin A, Bancel B, Trepo C, Bartsch H, Swenberg JA, Marion M. 2000. Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species. Int J Cancer 85(2):223-227. PMID:10629081
  • Christakos G, Hristopulos D, Bogaert P. 2000. On the physical geometry concept at the basis of space/time geostatistical hydrology. Adv Water Resour 23(8):799-810.
  • Christakos G, Hristopulos D, Kolovos A. 2000. Stochastic flowpath analysis of multiphase flow in random porous media. SIAM Journal on Applied Mathematics 60:1520-1542.
  • Christakos G, Papanicolaou V. 2000. Norm-dependent covariance permissibility of weakly homogeneous spatial random fields. Stochastic Environmental Research and Risk Assessment 14(6):471-478.
  • Christakos G, Serre ML. 2000. BME analysis of spatiotemporal particulate matter distributions in North Carolina. Atmos Environ (1994) 34(20):3393-3406.
  • Christakos G, Serre ML. 2000. Spatiotemporal analysis of environmental exposure-health effect associations. J Expo Sci Environ Epidemiol 10(2):168-187. PMID:10791598
  • Christakos G, Serre ML, Demyanov VV, Timonin V, Kanevski VM, Savelieva EA, Chernov S. 2000. BME analysis of neural network residual data from Chernobyl fallout: Bayesian and non-Bayesian approaches. In: Proceedings of GeoEnv2000 (3rd European Conference on Geostatistics for Environmental Applications).
  • D'Or D, Bogaert P, Christakos G. 2000. Application of BME to soil texture mapping. Stochastic Environmental Research and Risk Assessment 15(1):87-100.
  • Demyanov VV, Kanevski VM, Savelieva EA, Chernov S, Timonin V, Christakos G, Serre ML. 2000. Neural network residual BME analysis of Chernobyl fallout-Part I: Analysis and modelling of non-linear trends in soft data using neural networks. In: Proceedings of GeoEnv2000 (3rd European Conference on Geostatistics for Environmental Applications).
  • Egeghy PP, Tornero-Velez R, Rappaport SM. 2000. Environmental and biological monitoring of benzene during self-service automobile refueling. Environ Health Perspect 108:1195-1202. PMID:11133401
  • Farthing MW, Miller CT. 2000. A comparison of high-resolution, finite-volume, adaptive-stencil schemes for simulating advective-dispersive transport. Adv Water Resour 24:29-48.
  • Gray WG, Miller CT. 2000. Comment on "Dynamics of wetting fronts in porous media". Physical Review A E61:2150-2151. PMID:11046518
  • Ham AL, Ranasinghe A, Koc H, Swenberg JA. 2000. 4-Hydroxy-2-nonenal and ethyl linoleate from N2,3-ethenoguanine under peroxidizing conditions. Chem Res Toxicol 13:1243-1250.
  • Hertz-Picciotto I, Arrighi HM, Hu S. 2000. Does arsenic exposure increase the risk for circulatory disease?. Am J Epidemiol 151(2):174-181. PMID:10645820
  • Holt S, Roy G, Mitra SR, Upton PB, Bogdanffy MS, Swenberg JA. 2000. Deficiency of N-methylpurine-DNA-glycosylase expression in nonparenchymal cells, the target cell for vinyl chloride and vinyl fluoride. DNA Repair (Amst) 460(2):105-115. PMID:10882851
  • Kazunga C, Aitken MD. 2000. Products from the incomplete metabolism of pyrene by polycyclic aromatic hydrocarbon-degrading bacteria. Appl Environ Microbiol 66:1917-1922. PMID:10788360
  • Korte JE, Hertz-Picciotto I, Schulz MR, Ball LM, Duell EJ. 2000. The contribution of benzene to smoking-induced Leukemia. Environ Health Perspect 108(4):333-339. PMID:10753092
  • Kovitz JL, Christakos G, Serre ML. 2000. BME analysis of space/time distributions of PM10 over California. In: Proceedings of ISEA (International Society of Exposure Analysis).
  • Lin P, Sangaiah R, Ranasinghe A, Upton PB, La DK, Gold A, Swenberg JA. 2000. Formation of quinonoid-derived protein adducts in the liver and brain of Sprague-Dawley rats treated with 2,2',5,5'-tetrachlorobiphenyl. Chem Res Toxicol 13(8):710-718. PMID:10956058
  • Marx RB, Aitken MD. 2000. A material-balance approach for modeling bacterial chemotaxis to a consumable substrate in the capillary assay. Biotechnol Bioeng 68(3):308-315. PMID:10745199
  • Miller CT, Hill EH, Moutier M. 2000. Remediation of subsurface systems contaminated with dense organic liquids. Environ Sci Technol 34(4):719-724.
  • Nakamura J, La DK, Swenberg JA. 2000. 5'-Nicked apurinic/apyrimidinic sites are resistant to b-elimination by b-polymerase and are persistent in human cultured cells after oxidative stress. J Biol Chem 275(8):5323-5328.
  • Nylander-French LA. 2000. A tape-stripping method for measuring dermal exposure to multifunctional acrylates. Ann Occup Hyg 44:645-651. PMID:11108786
  • Rusyn I, Denissenko MF, Wong VA, Butterworth BE, Cunningham ML, Upton PB, Thurman RG, Swenberg JA. 2000. Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency. Carcinogenesis 21(12):2141-2145. PMID:11133801
  • Serre ML, Christakos G, Demyanov VV, Kanevski VM, Savelieva EA, Chernov S, Timonin V. 2000. Neural network residual BME analysis of Chernobyl fallout-Part II: Analysis of the soft data residual using the BME method. In: Proceedings of GeoEnv2000 (3rd European Conference on Geostatistics for Environmental Applications).
  • Serre ML, Christakos G, Howes J. 2000. Powering an Egyptian air quality information system with the BME space/time analysis toolbox. In: Proceedings of GeoEnv2000 (3rd European Conference on Geostatistics for Environmental Applications).
  • Swenberg JA, Christova-Gueoguieva NI, Upton PB, Ranasinghe A, Scheller NA, Wu K, Yen T, Hayes RB. 2000. 1,3-butadiene: cancer, mutations, and adducts. Part V: Hemoglobin adducts as biomarkers of 1,3-butadiene exposure and metabolism. HEI Research Report No. 92: 1,3-Butadiene and its metabolites: Interspecies comparison of carcinogenicity, mutagenicity and biomarkers. Part V. Hemoglobin adducts as biomarkers of butadiene exposure and metabolism 92:pp.191-219. PMID:10925842
  • Swenberg JA, Ham AL, Koc H, Morinello EJ, Ranasinghe A, Tretyakova N, Upton PB, Wu K. 2000. DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene. Mutat Res 464(1):77-86. doi:10.1016/S1383-5718(99)00168-0 PMID:10633179
  • Troester MA, Lindstrom AB, Waidyanatha S, Kupper LL, Rappaport SM. 2000. Stability of hemoglobin and albumin adducts of benzene oxide and 1,4-benzoquinone after administration of benzene to F344 rats. Toxicol Sci 54:88-94. PMID:10746935
  • Walker V, Wu K, Upton PB, Ranasinghe A, Scheller NA, Cho M, Vergnes JS, Skopek TR, Swenberg JA. 2000. Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide. Carcinogenesis 21(9):1661-1669. PMID:10964097
  • Williams GA, Miller CT, Kelley CT. 2000. Transformation approaches for simulating flow in variably saturated porous media. Water Resour Res 36(4):923-934.
  • Willson CS, Pau O, Pedit JA, Miller CT. 2000. Mass transfer rate limitation effects on partitioning tracer tests. J Contam Hydrol 45:79-97.

1999

  • Bogaert P, Serre ML, Christakos G. 1999. Efficient computational BME analysis of non-gaussian data in terms of transformation functions. In: Proceedings of the 5th Annual Conference of the International Association for Mathematical Geology. pp.57-62.
  • Chen S, Aitken MD. 1999. Salicylate stimulates the degradation of high-molecular weight polycyclic aromatic hydrocarbons by Pseudomonas saccharophila P15. Environ Sci Technol 33:435-439.
  • Christakos G. 1999. Review of "GeoEnvi-Geostatistics for Environmental Applications," by A. Soares, J. Gomez-Hernandez and R. Froidevaux (eds.). Environmental Geosciences 6:1-4.
  • Christakos G, Hristopulos D, Serre ML. 1999. BME studies of stochastic differential equations representing physical laws-Part I. In: Proceedings of the 5th Annual Conference of the International Association for Mathematical Geology. pp.63-68.
  • Christakos G, Kolovos A. 1999. A study of the spatiotemporal health impacts of ozone exposure. J Expo Sci Environ Epidemiol 9:322-335. PMID:10489157
  • Ham AL, Ranasinghe A, Morinello EJ, Nakamura J, Upton PB, Johnson F, Swenberg JA. 1999. Immunoaffinity/gas chromatography/high resolution mass spectrometry method for the detection of N2,3-ethenoguanine. Chem Res Toxicol 12:1240-1246. PMID:10604874
  • Hilpert M, Miller CT. 1999. Experimental investigation on the resonance of a liquid column in a capillary tube. Journal of Colloid and Interface Science 219:62-68. PMID:10527572
  • Holt S, Bogdanffy MS, Swenberg JA. 1999. The molecular dosimetry and repair of vinyl fluoride-induced DNA adducts. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.335.
  • Hristopulos D, Christakos G. 1999. Renormalization group analysis of permeability scaling. Stochastic Environmental Research and Risk Assessment 13:131-160.
  • Hristopulos D, Christakos G, Serre ML. 1999. Implementation of a space transform approach for solving the three-dimensional flow equation. SIAM Journal on Scientific Computing 20:619-647.
  • Hu S, Hertz-Picciotto I, Siemiatycki J. 1999. When to be skeptical of negative studies: Pitfalls in evaluating occupational risks in population-based case-control studies. Can J Public Health 90(2):138-142. PMID:10349223
  • Imhoff PT, Miller CT. 1999. Nonaqueous phase liquids in the subsurface: Effects of nonaqueous-aqueous mass transfer limitations. In: Groundwater Contamination Control. Computational Mechanics Publications, Southampton, United Kingdom.
  • Ito N, La DK, Holt S, Craft TR, Sills RC, Swenberg JA. 1999. Analysis of ras mutations in forestomach tumors from B6C3F1 mice exposed to 1,2,3-trichloropropane. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.137.
  • Kazunga C, Aitken MD, Gold A. 1999. Primary product of the horseradish peroxidase-catalyzed oxidation of pentachlorophenol. Environ Sci Technol 33:1408-1412.
  • Kees CE, Miller CT. 1999. C++ implementations of numerical methods for solving differential-algebraic equations: design and optimization considerations. Trans Math Softw 25:377-403.
  • La DK, Lin P, Swenberg JA. 1999. Analysis of DNA Adducts in rats chronically exposed to pentachlorophenol. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.330.
  • La DK, Swenberg JA. 1999. The induction of endogenous DNA adducts in tissues of Fischer-344 rats following gavage administration of 1,2,3-trichloropropane. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.131.
  • Lin P, Sangaiah R, Swenberg JA. 1999. Adducts of 2,3,2',5'-tetrachlorobiphenyl-derived ortho-quinone with rat liver proteins after metabolic activation in vitro. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.330.
  • Lin P, Waidyanatha S, Pollack GM, Swenberg JA, Rappaport SM. 1999. Dose-specific production of chlorinated quinone and semiquinone adducts in rodent livers following administration of pentachlorophenol. Toxicol Sci 47(1):126-133. PMID:10048161
  • Lindstrom AB, Yeowell-O'Connell K, Waidyanatha S, McDonald TA, Rappaport SM. 1999. Investigation of benzene oxide in bone marrow and other tissues of F344 rats following metabolism of benzene in vitro and in vivo. Chem Biol Interact 122(1):41-58. PMID:10475614
  • Marion M, Boivin-Angele S. 1999. Vinyl chloride-specific mutations in humans and animals. IARC Sci Publ 150:315-324. PMID:10626231
  • Marx RB, Aitken MD. 1999. Quantification of chemotaxis to naphthalene by Pseudomonas putida G7. Appl Environ Microbiol 65:2847-2852. PMID:10388674
  • Mitro KL, Scheller NA, Ranasinghe A, Swenberg JA. 1999. Quantitation of endogenous N2,3-ethenoguanine in human and rat liver DNA using high resolution mass spectrometry. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.847.
  • Nakamura J. 1999. Determination of spontaneous depurination and endogenous AP sites in organs of F344 rats using ASB method. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.648.
  • Nakamura J, Swenberg JA. 1999. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res 59(11):2522-2526. PMID:10363965
  • Nakamura J, Walker V, Upton PB, Swenberg JA. 1999. Characterization of a newly developed AP site assay that uses an aldehyde reactive probe-Slot-Blot method. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.480.
  • Pastore LM, Hertz-Picciotto I, Beaumont JJ. 1999. Risk of stillbirth from medications, illnesses and medical procedures. Paediatr Perinat Epidemiol 13(4):421-430. PMID:10563361
  • Pfaender FK. 1999. Unanswered Questions: The role of research. Bioavailability: Using what we know, learning what we need. National Environmental Policy Institute, Washington, D.C
  • Rappaport SM, Yeowell-O'Connell K. 1999. Protein adducts as dosimeters of human exposure to styrene, styrene-7, 8-oxide, and benzene. Toxicol Lett 108:117-126. PMID:10511253
  • Serre ML, Christakos G. 1999. BME studies of stochastic differential equations representing physical laws -part II. In: Proceedings of the 5th Annual Conference of the International Association for Mathematical Geology. pp.93-98.
  • Serre ML, Christakos G. 1999. Modern geostatistics: computational BME in the light of uncertain physical knowledge--the Equus Beds study. Stochastic Environmental Research and Risk Assessment 13:1-26.
  • Stringfellow WT, Chen S, Aitken MD. 1999. Induction of PAH degradation in a phenanthrene-degrading pseudomonad. In: Proceedings of the International In Situ and On-site Bioreclamation Symposium. San Diego, CA.
  • Swenberg JA, Bogdanffy MS, Ham AL, Holt S, Kim AH, Morinello EJ, Ranasinghe A, Scheller NA, Upton PB. 1999. Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride- induced carcinogenesis. IARC Sci Publ 150:29-43. PMID:10626206
  • Swenberg JA, Lehman-McKeeman LD. 1999. alpha 2-Urinary globulin-associated nephropathy as a mechanism of renal tubule cell carcinogenesis in male rats. IARC Sci Publ (147):95-118. PMID:10457913
  • Wagoner DB, Christman RF. 1999. Molar mass and size of Norwegian aquatic NOM by light scattering. Environ Int 25:275-284.
  • Williams GA, Miller CT. 1999. An evaluation of temporally adaptive transformation approaches for solving Richards' equation. Adv Water Resour 22:831-840.
  • Willson CS, Hall JL, Imhoff PT, Miller CT. 1999. Factors affecting bank formation during surfactant-enhanced mobilization of residual NAPL. Environ Sci Technol 33(14):2440-2446.
  • Wu K, Ranasinghe A, Upton PB, Scheller NA, Swenberg JA. 1999. Endogenous formation of the major DNA adduct of ethylene oxide in humans, rats, and mice. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.102.
  • Wu K, Ranasinghe A, Upton PB, Walker V, Swenberg JA. 1999. Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl)guanine formation in tissues of rodents. Carcinogenesis 20:1787-1792. PMID:10469625
  • Wu K, Scheller NA, Cho M, Ranasinghe A, Upton PB, Walker V, Swenberg JA. 1999. Molecular dosimetry of hydroxyethyl adducts in DNA and hemoglobin following exposure of rats and mice to ethylene. In: Proceedings of the Ninetieth Annual Meeting of the (AACR) American Association of Cancer Research, 1999. pp.839.
  • Wu K, Scheller NA, Ranasinghe A, Yen T, Sangaiah R, Giese RW, Swenberg JA. 1999. A gas chromatography/electron capture/negative chemical ionization-high resolution mass spectrometry method for analysis of endogenous and exogenous N7-(2-hydroxyethyl)guanine in rodents and its potential for human biological monitoring. Chem Res Toxicol 12(8):722-729. PMID:10458706

1998

  • Aitken MD, Stringfellow WT, Nagel RD, Kazunga C, Chen S. 1998. Characteristics of phenanthrene-degrading bacteria isolated from soils contaminated with polycyclic aromatic hydrocarbons. Can J Microbiol 44(8):743-752. PMID:9830104
  • Cassiani G, Christakos G. 1998. Analysis and estimation of spatial non-homogeneous natural processes using secondary information. Math Geol 30(1):57-76.
  • Christakos G. 1998. Multi-point BME space/time mapping of environmental variables. In: Computational Methods in Water Resources, XII(2): Computational Methods in Surface and Groundwater Transport. Computational Mechanics Publications, Southampton, United Kingdom. pp.289-296.
  • Christakos G. 1998. Spatiotemporal information systems in soil and environmental sciences. Geoderma 85:141-179.
  • Christakos G, Hristopulos D. 1998. Stochastic indicator analysis of contaminated sites. Journal of Applied Probability 34(4):988-1008.
  • Christakos G, Hristopulos D, Li X. 1998. Multiphase flow in heterogeneous porous media: a stochastic differential geometry viewpoint. Water Resour Res 34(1):93-102.
  • Christakos G, Li X. 1998. Bayesian maximum entropy analysis and mapping: A farewell to Kriging estimators?. Math Geol 30(4):435-462.
  • Christakos G, Vyas VM. 1998. A composite spatiotemporal study of ozone distribution over the eastern United States. Atmos Environ (1994) 32(16):2845-2857.
  • Christakos G, Vyas VM. 1998. A novel method for studying population health impacts of spatiotemporal ozone distribution. Soc Sci Med 47(8):1051-1066. PMID:9723851
  • Cistulli CA, Kaufmann WK. 1998. P53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts. Cancer Res 58:1993-2002. PMID:9581844
  • Din-Dzietham R, Hertz-Picciotto I. 1998. Infant mortality differences between Whites and African Americans: the effect of maternal education. Am J Public Health 88(4):651-656. PMID:9551012
  • Guthrie EA, Pfaender FK. 1998. Reduced pyrene bioavailability in microbially active soils. Environ Sci Technol 32(4):501-508.
  • Ham AL, Swenberg JA. 1998. Immunoaffinity (IA) gas chromatography/mass spectometry (GC/MS) method for N2,3-ethenoguanine demonstrates importance of hydrolysis method for adduct quantitation. Fundam Appl Toxicol 42:180.
  • Hertz-Picciotto I, Din-Dzietham R. 1998. Comparisons of infant mortality using a percentile-based method of standardization for birthweight or gestational age. Epidemiology 9(1):61-67. PMID:9430270
  • Holt S, Sangaiah R, Swenberg JA. 1998. Detection of 1,N6-ethenoadenine in rat urine after chloroethylene oxide exposure. Carcinogenesis 19(10):1763-1769. PMID:9806156
  • Holt S, Scheller NA, Mitra SR, Bogdanffy MS, Swenberg JA. 1998. Formation and repair of vinyl fluoride-induced DNA adducts. Fundam Appl Toxicol 42:180.
  • Imhoff PT, Arthur MH, Miller CT. 1998. Complete dissolution of trichloroethylene in saturated porous media. Environ Sci Technol 32(16):2417-2424.
  • Kelley CT, Miller CT, Tocci MD. 1998. Termination of Newton/chord iterations and the method of lines. SIAM Journal on Scientific Computing 19:280-290.
  • Law JM, Bull M, Nakamura J, Swenberg JA. 1998. Molecular dosimetry of DNA adducts in the medaka small fish model. Carcinogenesis 19(3):515-518. PMID:9525288
  • Li Y, Asherova M, Brandt-Rauf PW. 1998. Mutant oncoprotein biomarkers in chemical carcinogenesis. In: Biomarkers: Medical and Workplace Applications. Joseph Henry Press, Washington, DC. pp.345-353.
  • Lindstrom AB, Yeowell-O'Connell K, Waidyanatha S, McDonald TA, Golding BT, Rappaport SM. 1998. Formation of hemoglobin and albumin adducts of benzene oxide in mouse, rat, and human blood. Chem Res Toxicol 11:302-310. PMID:9548800
  • Marion M. 1998. Critical genes as early warning signs: example of vinyl chloride. Toxicol Lett 102/103:603-607. PMID:10022320
  • Miller CT, Christakos G, Imhoff PT, McBride JF, Pedit JA, Trangenstein JA. 1998. Multiphase flow and transport modeling in heterogeneous porous media: Challenges and approaches. Adv Water Resour 21(2):77-120.
  • Miller CT, Gleyzer SN, Imhoff PT. 1998. Numerical modeling of NAPL dissolution fingering in porous media. In: Physical Nonequilibrium in Soils: Modeling and Application. Ann Arbor Press, Ann Arbor, MI.
  • Miller CT, Williams GA, Kelley CT, Tocci MD. 1998. Robust solution of Richards' equation for non-uniform porous media. Water Resour Res 34:2599-2610.
  • Nakamura J, Walker V, Upton PB, Chiang S, Kow YW, Swenberg JA. 1998. Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions. Cancer Res 58(2):222-225. PMID:9443396
  • Ploch SA, Nakamura J, Swenberg JA, Di Giulio RT. 1998. Assessment of AP site formation in isolated hepatocytes from brown bullhead upon treatment with benzo(a)pyrene. Fundam Appl Toxicol 42:82.
  • Ranasinghe A, Ham AL, Morinello EJ, Swenberg JA. 1998. Quantitation of 1, N2-ethenoguanine and N2, 3-ethenoguanine by IAC/GC/ECNCI/HRMS. In: Proceedings of the 46th ASMS (American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics.
  • Ranasinghe A, Scheller NA, Wu K, Upton PB, Swenberg JA. 1998. Application of gas chromatography/electron capture negative chemical ionization/high resolution mass spectrometry for analysis of DNA and protein adducts. Chem Res Toxicol 11:520-526. PMID:9585483
  • Smith SJ, Li Y, Whitley R, Marion M, Partilo S, Carney WP, Brandt-Rauf PW. 1998. Molecular epidemiology of p53 mutations in workers exposed to vinyl chloride. Am J Epidemiol 147(3):302-308. PMID:9482505
  • Tocci MD, Kelley CT, Miller CT, Kees CE. 1998. Inexact Newton methods and the method of lines for solving Richards' equation in two space dimensions. Computational Geosciences 2(4):291-309. doi:10.1023/A:1011562522244
  • Wagoner DB, Christman RF. 1998. Molar masses and radii of humic substances measured by light scattering. Acta Hydrochimica et Hydrobiologica 26(3):191-195.
  • Waidyanatha S, Yeowell-O'Connell K, Rappaport SM. 1998. A new assay for albumin and hemoglobin adducts of 1,2- and 1,4-benzoquinones. Chem Biol Interact 115:117-139. PMID:9826945
  • Yen T, Holt S, Sangaiah R, Gold A, Swenberg JA. 1998. Quantitation of 1,N6 ethenoadenine in rat urine by immunoaffinity extraction combined with liquid chromatography/electrospray ionization mass spectrometry. Chem Res Toxicol 11(7):810-815. PMID:9671544
  • Yeowell-O'Connell K, Rothman N, Smith MT, Hayes RB, Li G, Waidyanatha S, Dosemeci M, Zhang L, Yin S, Titenko-Holland N, Rappaport SM. 1998. Hemoglobin and albumin adducts of benzene oxide among workers exposed to high levels of benzene. Carcinogenesis 19(9):1565-1571. PMID:9771926

1997

  • Barbin A, Froment O, Boivin S, Marion M, Belpoggi F, Maltoni C, Montesano R. 1997. P53 Gene mutation pattern in rat liver tumors induced by vinyl chloride. Cancer Res 57(9):1695-1698. PMID:9135010
  • Bogaert P, Christakos G. 1997. Spatiotemporal analysis and processing of thermometric data over Belgium. J Geophys Res Atmos 102(D22):831-846.
  • Bogaert P, Christakos G. 1997. Stochastic analysis of spatiotemporal solute content measurements using a regressive model. Stochastic Hydrology and Hydraulics 11(4):267-295.
  • Carmichael LM, Christman RF, Pfaender FK. 1997. Desorption and mineralization kinetics of phenanthrene and chrysene in contaminated soils. Environ Sci Technol 31:126-132.
  • Carmichael LM, Pfaender FK. 1997. Polynuclear aromatic hydrocarbon metabolism in soils: relationships to soil characteristics and preexposure. Environ Toxicol Chem 16(4):666-675.
  • Carmichael LM, Pfaender FK. 1997. The effect of inorganic and organic supplements on the microbial degradation of phenanthrene and pyrene in soils. Biodegradation 8:1-13. PMID:9290252
  • Christakos G. 1997. Stochastic Radon operators in porous media hydrodynamics. Quarterly of Applied Mathematics LV:89-112.
  • Christakos G, Lai J. 1997. A study of the breast cancer dynamics in North Carolina. Soc Sci Med 45(10):1503-1517. PMID:9351140
  • Din-Dzietham R, Hertz-Picciotto I. 1997. Relationship of education to the racial gap in neonatal and postneonatal mortality. Arch Pediatr Adolesc Med 151:787-792. PMID:9265879
  • Goldsmith DF, Hertz-Picciotto I. 1997. Criteria for conducting quantitative risk assessments for silica. J Expo Sci Environ Epidemiol 7(3):367-375. PMID:9246598
  • Guthrie EA, Pfaender FK. 1997. Microbial role in regulation of PAH bioavailability. OECD Workshop Mexico on Biotechnology for Water Use and Conservation, Oct. 20, Cocoyoc, Mexico. OECD Proceedings 221-238.
  • Guthrie EA, Pfaender FK. 1997. The fate of pyrene aged in soil. In: Proceedings of the ASI/NATO (Advanced Study Institute/ North Atlantic Treaty Organization) Conference on Bioavailability of Organic Pollutants. Jesenik, Czech Republic.
  • Hertz-Picciotto I, Korte JE, Schulz MR, Chiang T, Ball LM. 1997. Carbon black risk assessment comparison is flawed. Regul Toxicol Pharmacol 26(3):338-339. PMID:9441924
  • Hertz-Picciotto I, Schulz MR, Chiang T, Duell EJ, Korte JE, Ball LM. 1997. What causes bladder cancer in smokers? Questions from a quantitative risk assessment. In: Presented at the Sixteenth Annual Symposium on Polycyclic Aromatic Compounds. Charlotte, NC.
  • Hertz-Picciotto I, Schulz MR, Chiang T, Duell EJ, Korte JE, Ball LM. 1997. What causes lung cancer in smokers? Answers from a quantitative risk assessment. Epidemiology 8:S60.
  • Hristopulos D, Christakos G. 1997. A variational calculation of the effective fluid permeability of heterogeneous media. Physical Review A 55:7288-7298.
  • Hristopulos D, Christakos G. 1997. An analysis of hydraulic conductivity upscaling. Proc. Sec. World Congress of Nonlinear Analysts. Nonlinear Analysis: Theory, Methods & Applications 30(8):4979-4984.
  • Hristopulos D, Christakos G. 1997. Diagrammatic theory of nonlocal effective hydraulic conductivity. Stochastic Hydrology and Hydraulics 11:369-395.
  • Imhoff PT, Frizzell A, Miller CT. 1997. An evaluation of thermal effects on the dissolution of a nonaqueous phase liquid in porous media. Environ Sci Technol 31(6):1615-1622.
  • Kaufmann WK, Byrd LL, Palmieri D, Nims RW, Rice JM. 1997. TGF-± sustains clonal expansion by promoter-dependent, chemically initiated rat hepatocytes. Carcinogenesis 18(18):1381-1387. PMID:9230284
  • Korte JE, Chiang T, Duell EJ, Hertz-Picciotto I, Ball LM. 1997. Does vinyl chloride induce primary liver cancer in smokers?. Epidemiology 8:S60.
  • La DK, Swenberg JA. 1997. Carcinogenic alkylating agents. In: Comprehensive Toxicology, Vol. 12, Chemical Carcinogens and Anticarcinogens. Elsevier Science, Oxford, United Kingdom. pp.111-140.
  • Lin P, Waidyanatha S, Pollack GM, Rappaport SM. 1997. Dosimetry of chlorinated quinone metabolites of pentachlorophenol in the livers of rats and mice based upon measurement of protein adducts. Toxicol Appl Pharmacol 145(2):399-408. PMID:9266814
  • Lindstrom AB, Yeowell-O'Connell K, Waidyanatha S, Golding BT, Tornero-Velez R, Rappaport SM. 1997. Measurement of benzene oxide in the blood of rats following administration of benzene. Carcinogenesis 18:1637-1641. PMID:9276641
  • Pastore LM, Hertz-Picciotto I, Beaumont JJ. 1997. Risk of stillbirth from occupational and residential exposures. J Occup Environ Med 54(7):511-518. PMID:9282129
  • Roper JC, Pfaender FK. 1997. Effect of repeated additions on phenanthrene mineralization and toxicity in soil. In: Proceedings of the Society for Environmental Toxicology and Chemistry Annual Meeting. San Francisco, CA.
  • Scheller NA, Ranasinghe A, Bogdanffy MS, Swenberg JA. 1997. Detection of N2,3-ethenoguanine by GC/HR-MS in brains and kidneys in vinyl fluoride exposed rodents. Fundam Appl Toxicol 36:94.
  • Schulz MR, Chiang T, Korte JE, Duell EJ, Hertz-Picciotto I, Ball LM. 1997. What causes bladder cancer in smokers? Questions from a quantitative risk assessment. Epidemiology 8:S60.
  • Swenberg JA. 1997. Generating data for scientifically-based risk assessment. Fundam Appl Toxicol 36:286.
  • Swenberg JA. 1997. In vivo studies on the formation and repair of DNA adducts. In: Proceedings of Environmental Mutagen Society Meeting, 1997. Minneapolis, MN.
  • Vyas VM, Christakos G. 1997. Spatiotemporal analysis and mapping of sulfate deposition data over the conterminous U.S.A. Atmos Environ (1994) 31:3623-3633.
  • Wagoner DB, Christman RF, Cauchon G, Paulson R. 1997. Molar mass and size of Suwannee River natural organic matter using multi-angle laser light scattering. Environ Sci Technol 31(3):937-941.
  • Wu K, Ranasinghe A, Scheller NA, Upton PB, Swenberg JA. 1997. Mechanism-based risk assessment: utility of DNA adducts in model selection. Fundam Appl Toxicol 36:97.
  • Yen T, Wu K, Holt S, Sangaiah R, Swenberg JA. 1997. Determination of DNA adducts from ethylene oxide and vinyl chloride exposure. In: Proceedings of the 45th AMS (American Society of Microbiology) Conference on Mass Spectrometry and Allied Topics. pp.295.

1996

  • Aitken MD. 1996. Emerging Concepts in the Biodegradation and Bioremediation of Polycyclic Aromatic Hydrocarbons. In: Proceedings of the Ninth Biennial Congress, South African Society for Microbiology. Pretoria, South Africa.
  • Chen S, Kazunga C, Aitken MD. 1996. Co-induction of Low- and High-Molecular Weight PAH Degradation in Pseudomonas saccharophila P15. In: The 96th General Meeting of the American Society for Microbiology. Washington, DC. pp.445.
  • Chiang S, Swenberg JA, Weisman WA, Skopek TR. 1996. Mutagenicity of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line. Carcinogenesis 18(1):31-36. PMID:9054586
  • Christakos G, Bogaert P. 1996. Spatiotemporal analysis of springwater ion processes derived from measurements at the Dyle Basin in Belgium. IEEE Transactions on Geoscience and Remote Sensing 34(3):626-642.
  • Christakos G, Hristopulos D. 1996. Characterization of atmospheric pollution by means of stochastic indicator parameters. Atmos Environ (1994) 30(22):3811-3823.
  • Christakos G, Hristopulos D. 1996. Stochastic indicators for waste site characterization. Water Resour Res 32(8):2563-2578.
  • Christakos G, Raghu VR. 1996. Dynamic stochastic estimation of physical variables. Math Geol 28(3):341-365.
  • Christova-Gueoguieva NI, Yen T, Scheller NA, Holt S, Swenberg JA. 1996. Quantitation of N2,3-ethenoguanine (epsilonG) in rat liver by liquid chromatography-electrospray mass spectrometry. Environ Health Perspect 30(1,part2):235.
  • Grimberg SJ, Miller CT, Aitken MD. 1996. Surfactant-enhanced dissolution of phenanthrene into water for laminar flow conditions. Environ Sci Technol 30(10):2967-2974.
  • Grimberg SJ, Stringfellow WT, Aitken MD. 1996. Quantifying the biodegradation of phenanthrene by Pseudomonas stutzeri P16 in the presence of a nonionic surfactant. Appl Environ Microbiol 62(7):2387-2392. PMID:8779577
  • Guichard Y, El Ghissassi F, Nair J, Bartsch H, Barbin A. 1996. Formation and accumulation of DNA ethenobases in adult Sprague-Dawley rats exposed to vinyl chloride. Carcinogenesis 17(8):1553-1559. PMID:8761409
  • Guthrie EA, Pfaender FK. 1996. Pyrene Mineralization in Pristine Soils Treated with Vegetation or UV light. In: Proceedings of the 96th General Meeting of the American Society of Microbiology. New Orleans, LA.
  • Guthrie EA, Pfaender FK. 1996. The Fate of 14C-Pyrene in Soils and Vegetated Soils. In: Proceedings of the 212th National Meeting of the American Chemical Society, August 25-29, 1996. Orlando, FL.
  • Guthrie EA, Pfaender FK. 1996. The Fate of Pyrene and Chrysene in PAH Mixtures. In: 18th Annual Meeting of the Society of Environmental Toxicology and Chemistry. Washington, DC.
  • Holt S, Swenberg JA. 1996. Age-dependent modulation of tissue-specific repair activity for methylpurine glycosylase. Environ Health Perspect 30(1,part2):236.
  • Imhoff PT, Miller CT. 1996. Dissolution fingering during the solubilization of nonaqueous phase liquids in saturated porous media, 1, Model predictions. Water Resour Res 32(7):1919-1928.
  • Imhoff PT, Thyrum GP, Miller CT. 1996. Dissolution fingering during the solubilization of nonaqueous phase liquids in saturated porous media, 2, Experimental observations. Water Resour Res 32(7):1929-1942.
  • Kazunga C, Aitken MD. 1996. Mineralization and Transformation of High Molecular Weight Polycyclic Aromatic Hydrocarbons by Phenanthrene Degrading Soil Bacteria. In: Proceedings of the Ninth Biennial Congress, South African Society for Microbiology. Pretoria, South Africa.
  • La DK, Schoonhoven R, Ito N, Swenberg JA. 1996. The effects of exposure route on DNA adduct formation and cellular proliferation by 1,2,3-trichloropropane. Toxicol Appl Pharmacol 140(1):108-114. PMID:8806876
  • La DK, Swenberg JA, Ham AL, Koc H, Morinello EJ, Ranasinghe A, Tretyakova N, Upton PB, Wu K. 1996. DNA adducts: Biological markers of exposure and potential applications to risk assessment. Mutat Res 365:129-146. PMID:8898994
  • Lin P, Waidyanatha S, Rappaport SM. 1996. Investigation of liver binding of pentachlorophenol based upon measurement of protein adducts. Biomarkers 1:232-243. PMID:23888990
  • Okuda I, McBride JF, Gleyzer SN, Miller CT. 1996. An investigation of physicochemical transport processes affecting the removal of residual DNAPL by nonionic surfactant solutions. Environ Sci Technol 30(6):1852-1860.
  • Oliver LD, Christakos G. 1996. Boundary condition sensitivity analysis of the stochastic flow equation. Adv Water Resour 19(2):109-120.
  • Pedit JA, Miller CT. 1996. Comment on "A distributed reactivity model for sorption by soils and sediments. 4. Intraparticle heterogeneity and phase-distribution relationships under nonequilibrium conditions". Environ Sci Technol 30(10):3128-3129.
  • Ranasinghe A, Scheller NA, Wu K, Swenberg JA. 1996. GC/ECNCI/MS/MS Analysis of electrophore-labeled DNA adducts. In: Proceedings of the 44th ASMS (American Society for Mass Spectrometry) on Mass Spectrometry and Allied Topics. Portland, OR.
  • Rappaport SM, McDonald TA, Yeowell-O'Connell K. 1996. The use of protein adducts to investigate the disposition of reactive metabolites of benzene. Environ Health Perspect 104(S6):1235-1237. PMID:9118898
  • Roper JC, Pfaender FK. 1996. Pyrene, Chrysene, and Salicylic Acid Fate in Surface Soil Microcosms. In: Proceedings of American Society for Microbiology Annual Meeting, 1996. New Orleans, LA.
  • Scheller NA, Ranasinghe A, Christova-Gueoguieva NI, Yen T, Ham AL, Swenberg JA. 1996. Detection of Endogenous N2,3-ethenoguanine by GC/ECNCI/MS. In: Proceedings of the 44th ASMS (American Society for Mass Spectrometry) on Mass Spectrometry and Allied Topics. Portland, OR. pp.781.
  • Scheller NA, Ranasinghe A, Yen T, Christova-Gueoguieva NI. 1996. Quantitation of endogenous ethenoguanine by GC/ECNCI/HRMS. In: Proceedings of the 44th ASMS (American Society for Mass Spectrometry) on Mass Spectrometry and Allied Topics. Portland, OR.
  • Swenberg JA, La DK, Scheller NA, Wu K. 1996. Dose-response relationships for carcinogens. Toxicol Lett 82-3:751-756. PMID:8597138
  • Swenberg JA, Scheller NA, Ranasinghe A, Upton PB, Christova-Gueoguieva NI, Bogdanffy MS. 1996. Molecular dosimetry of N2,3-ethenoguanine in DNA of vinyl fluoride-exposed rats: relationship to hemangiosarcoma. Environ Health Perspect 30(1,part2):235.
  • Waidyanatha S, Lin P, Rappaport SM. 1996. Characterization of chlorinated adducts of hemoglobin and albumin following administration of pentachlorophenol to rats. Chem Res Toxicol 9(3):647-653. PMID:8728511
  • Yen T, Charles MJ, Voyksner RD. 1996. Processes that affect electrospray ionization-mass spectrometry of nucleobases and nucleosides. J Am Soc Mass Spectrom 7(11):1106-1108. PMID:24203072
  • Yen T, Christova-Gueoguieva NI, Scheller NA, Holt S, Swenberg JA, Charles MJ. 1996. HPLC/ESI/MS May be the Technique of Choice for the Analysis of Certain DNA Adducts. In: Proceedings of the 44th ASMS (American Society for Mass Spectrometry) on Mass Spectrometry and Allied Topics. Portland, OR. pp.780.
  • Yen T, Christova-Gueoguieva NI, Scheller NA, Holt S, Swenberg JA, Charles MJ. 1996. Quantitative analysis of the DNA adduct N2,3-ethenoguanine using liquid chromatography/electrospray ionization mass spectrometry. J Mass Spectrom 31(11):1271-1276. PMID:8946734
  • Yeowell-O'Connell K, McDonald TA, Rappaport SM. 1996. Analysis of hemoglobin adducts of benzene oxide by gas chromatography-mass spectrometry. Anal Biochem 237:49-55. PMID:8660536

1995

  • Arthur MH, Imhoff PT, Miller CT. 1995. Dissolution of nonaqueous phase liquids at low saturation. EOS: Transactions of the American Geophysical Union 76(17):S129.
  • Brandt-Rauf PW, Marion M, De Vivo I. 1995. Mutant p21 protein as a biomarker of chemical carcinogenesis in humans. In: Biomarkers and Occupational Health: Progress and Perspectives. Joseph Henry Press, Washington, DC. pp.163-173.
  • Carmichael LM, Pfaender FK. 1995. Comparison of polycyclic aromatic hydrocarbon degradation in four contaminated soils. In: Proceedings of the Third International Symposium, San Diego, CA on In Situ and On-Site Bioreclamation, Third International Symposium. San Diego, CA.
  • Carmichael LM, Pfaender FK. 1995. The microbial degradation of high molecular weight PAH in soils. In: Proceedings of American Society for Microbiology, 1995 National Meeting.
  • Chiang S, Craft TR, Skopek TR, Swenberg JA. 1995. Mutation spectra of vinyl chloride (VC) and chloroethylene oxide (CEO) at the hprt gene in metabolically-competent human lymphoblastoid lines. International Toxicologist 7(1):46P9.
  • Chiang S, Skopek TR, Swenberg JA. 1995. Mutagenicity of vinyl chloride and its metabolites, and vinyl fluoride in a metabolically competent human lymphoblastoid line. Environ Health Perspect 15(1):79.
  • Chiao C, Zhang Y, Kaufman DG, Kaufmann WK. 1995. Derivation of phenobarbital-responsive immortal rat hepatocytes. Am J Pathol 146(5):1248-1259. PMID:7747817
  • Chiao C, Zhang Y, Kaufman DG, Kaufmann WK. 1995. Phenobarbital modulates the type of cell death by initiated hepatocytes during deprivation of serum in vitro. Hepatology 22(1):297-303. PMID:7601424
  • Christakos G, Hristopulos D, Miller CT. 1995. Stochastic diagrammatic analysis of groundwater flow in heterogeneous soils. Water Resour Res 31(7):1687-1703.
  • Corson D, Pedit JA, Miller CT. 1995. Sorption of naphthalene and phenanthrene by aquifer sands. EOS: Transactions of the American Geophysical Union 76(17):S136.
  • El Ghissassi F, Barbin A, Nair J, Bartsch H. 1995. Formation of 1,N6-ethenoadenine and 3,N4-ethenocytosine by lipid peroxidation products and nucleic acid bases. Chem Res Toxicol 8:278-283. PMID:7766812
  • Guthrie EA, Pfaender FK. 1995. Microbially mediated fate of pyrene and phenanthrene in soil. In: Proceedings of the 95th General Meeting of the American Society of Microbiology. Washington, DC.
  • Guthrie EA, Pfaender FK. 1995. Microbially mediated fate of pyrene and phenanthrene in soil. In: Proceedings of the Third International Symposium, San Diego, CA on In Situ and On-Site Bioreclamation, Third International Symposium. San Diego, CA.
  • Guthrie EA, Pfaender FK. 1995. Microbially mediated incorporation of 14C-pyrene into soil organic matter. In: 17th Annual Meeting, November 17-22.
  • Hertz-Picciotto I. 1995. Epidemiology and quantitative risk assessment: a bridge from science to policy. Am J Public Health 85(4):484-491. PMID:7702110
  • Holt S, Swenberg JA. 1995. Detection of 1,N6-ethenoadenine excreted in rat urine after chloroethylene oxide exposure. Environ Health Perspect 15(1):77.
  • Imhoff PT, Gleyzer SN, McBride JF, Vancho LA, Okuda I, Miller CT. 1995. Cosolvent-enhanced remediation of residual dense nonaqueous phase liquids: experimental investigation. Environ Sci Technol 29(8):1966-1976. PMID:22191343
  • Kumaresan KR, Hang B, Lambert MW. 1995. Human endonucleolytic incision of DNA 3` and 5` to a site-directed psoralen monoadduct and interstrand cross-link. J Biol Chem 270(51):30709-30716. PMID:8530510
  • Nair J, Barbin A, Guichard Y, Bartsch H. 1995. 1,N6-ethenodeoxyadenosine and 3,N4- ethenodeoxycytidine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabelling. Carcinogenesis 16(3):613-617.
  • Oliver LD, Christakos G. 1995. Diagrammatic solutions for hydraulic head moments in 1-D and 2-D Bounded domains. Stochastic Hydrology and Hydraulics 9:269-296.
  • Pedit JA, Miller CT. 1995. Heterogeneous sorption processes in subsurface systems: 2 diffusion modeling approaches. Environ Sci Technol 29(7):1766-1722. PMID:22176448
  • Rappaport SM, Symanski E, Yager JW, Kupper LL. 1995. The relationship between environmental monitoring and biological markers in exposure assessment. Environ Health Perspect 103(supp.3):49-53. PMID:7635112
  • Sarr DH, Kazunga C, Charles MJ, Pavlovich JH, Aitken MD. 1995. Decomposition of tetrachloro-1,4-benzoquinone (p-chloranil) in aqueous solution. Environ Sci Technol 29(11):2735-2740. PMID:22206518
  • Scheller NA, Ranasinghe A, Kim AH, Holt S, Bogdanffy MS, Swenberg JA. 1995. High resolution GC/MS detection of N2,3-ethenoguanine in livers of control and vinyl fluoride-exposed B6C3F1 mice. International Toxicologist 7(1):6P21.
  • Scheller NA, Sangaiah R, Ranasinghe A, Amarnath V, Gold A, Swenberg JA. 1995. Synthesis of [4,5,6,8-13C4]guanine, a reagent for the production of internal standards of guanyl DNA adducts. Chem Res Toxicol 8(3):333-337. PMID:7578918
  • Stringfellow WT, Aitken MD. 1995. Competitive metabolism of naphthalene, methylnaphthalenes and fluorene by phenanthrene-degrading pseudomonads. Appl Environ Microbiol 61:357-362. PMID:7887615
  • Stringfellow WT, Chen S, Aitken MD. 1995. Induction of PAH degradation in a phenanthrene-degrading pseudomonad. In: Microbial Processes for Bioremediation. Battelle Press, Columbus, OH. pp.83-89.
  • Swenberg JA. 1995. Bioassay design and MTD setting: old methods and new approaches. Regul Toxicol Pharmacol 21:44-51. PMID:7784635
  • Swenberg JA. 1995. Carcinogenesis. In: Patty's Industrial Hygiene and Toxicology, 3rd edition, Volume 4, Part B. Wiley and Sons, New York, NY. pp.255-273.
  • Szatkowski A, Imhoff PT, Miller CT. 1995. Development of a correlation for aqueous-vapor phase mass transfer in porous media. J Contam Hydrol 18(1):85-106.
  • Thompkins J, Guthrie EA, Pfaender FK. 1995. Toxicity evaluation of PAH mixtures using microtox. In: 17th Annual Meeting, November 17-22.
  • Yang A, Miller CT. 1995. Random sphere packings for examination of pore-scale characteristics. EOS: Transactions of the American Geophysical Union 76(17):S129.
  • Yen T, Christova-Gueoguieva NI, Scheller NA, Swenberg JA, Charles MJ. 1995. Quantitative analysis of DNA adducts by using HPLC/ESI-MS. In: Proceedings of the 43rd ASMS (American Society for Mass Spectrometry) Conference on Mass Spectrometry and Allied Topics. pp.497.
  • Zhang Y, Chiao C, Byrd LL, Kaufman DG, Kaufmann WK. 1995. Liver tumor promotion and the suppression of p53-dependent cell cycle checkpoint function. In: Liver Regeneration and Carcinogenesis: molecular and cellular mechanisms. Academic Press,
  • Tedder DW, ed. 1995. Practical considerations in the application of enzyme-catalyzed oxidation. In: Emerging Technologies in Hazardous Waste Management VII. American Chemical Society, Washington, DC. pp.418-420.

1991

  • Christakos G. 1991. A theory of spatiotemporal random fields and its application to space-time data processing. IEEE Trans Syst Man Cybern 21(4):861-875.
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