Superfund Research Program
Elucidating Risks: From Exposure and Mechanism to Outcome
Center Director: Rebecca C. Fry
Grant Number: P42ES005948
Funding Period: 1992-2018
Program Links
Title: CpG island methylation data from maternal venous blood and infant cord blood samples
Accession Number: GSE67976
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE67976
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Methylation profiling by genome tiling array
Organism(s): Homo sapiens
Summary: The biological mechanism of cadmium's effects is poorly characterized. This data was generated in order to help better understand the epigenetic role that Cadmium plays. We used the MIRA assay and the Affymetrix Human Promoter 1.0R Array in order to measure methylation levels in promoter regions.
Publication(s) associated with this dataset:- Sanders AP, Smeester L, Rojas D, DeBussycher T, Wu MC, Wright FA, Zhou Y, Laine JE, Rager JE, Swamy GK, Ashley-Koch A, Miranda ML, Fry RC. 2013. Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. Epigenetics 9(2):29-38. doi:10.4161/epi.26798 PMID:24169490 PMCID:PMC3962531